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 TitleAuthors / EditorsDate
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Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software Marsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef 2018
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Hepatocyte Concentrations of Indocyanin Green (ICG) Reflects Transfer Rates Across Membrane Transporters Cusin, Fabien; Azevedo, Liliana; Bonnaventure, Pierre; Desmeules, Jules Alexandre; ... Pastor, Catherine 2017
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Plasma concentrations of transdermal fentanyl and buprenorphine in pigs (Sus scrofa domesticus) Osorio Lujan, Suzanne; Habre, Walid; Daali, Youssef; Pan, Zhaoxin; Kronen, Peter W 2017
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The Association of Combined GSTM1 and CYP2C9 Genotype Status with the Occurrence of Hemorrhagic Cystitis in Pediatric Patients Receiving Myeloablative Conditioning Regimen Prior to Allogeneic Hematopoietic Stem Cell Transplantation Uppugunduri, Chakradhara Rao S; Storelli, Flavia; Mlakar, Vid; Huezo-Diaz Curtis, Patricia; ... Ansari Djaberi, Marc Georges 2017
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Usefulness of PBPK Modeling in Incorporation of Clinical Conditions in Personalized Medicine Marsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef 2017
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Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future Darwich, A S; Ogungbenro, K; Vinks, A A; Powell, J R; ... Rostami-Hodjegan, A 2017
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Impact of CYP2D6 functional allelic variations on phenoconversion and drug-drug interactions Storelli, Flavia; Matthey, Alain; Lenglet, Sébastien; Thomas, Aurélien; ... Daali, Youssef 2017
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Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective study Lloret-Linares, Célia; Rollason Gumprecht, Victoria; Ing Lorenzini, Kuntheavy; Samer, Caroline Flora; ... Besson, Marie 2017
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Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferases Romand, Stéphanie Anne; Spaggiari, Dany; Marsousi, Niloufar; Samer, Caroline Flora; ... Rudaz, Serge 2017
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Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis Seredenin, Tamara; Nayernia, Zeynab; Sorce, Silvia; Maghzal, Ghassan J; ... Jaquet, Vincent 2016
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The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesia Ralvenius, William T; Acuña, Mario A; Benke, Dietmar; Matthey, Alain; ... Besson, Marie 2016
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An extensive cocktail approach for rapid risk assessment of in vitro CYP450 direct reversible inhibition by xenobiotic exposure Spaggiari, Dany; Daali, Youssef; Rudaz, Serge 2016
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Pharmacogenomics of Oral Antithrombotic Drugs Storelli, Flavia; Daali, Youssef; Desmeules, Jules Alexandre; Reny, Jean-Luc; Fontana, Pierre 2016
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Aspirin response: Differences in serum thromboxane B2 levels between clinical studies Brun, Charlotte; Daali, Youssef; Combescure, Christophe; Zufferey Bakos, Anne; ... Frelinger, Andrew L (3rd) 2016
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Severe Vincristine-Induced Neuropathic Pain in a CYP3A5 Nonexpressor With Reduced CYP3A4/5 Activity: Case Study Bosilkovska Weisskopf, Marija; Ing Lorenzini, Kuntheavy; Uppugunduri Satyanarayana, Chakradhara Rao; Desmeules, Jules Alexandre; ... Escher, Monica 2016
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Intestinal permeability and P-glycoprotein-mediated efflux transport of ticagrelor in Caco-2 monolayer cells Marsousi, Niloufar; Doffey-Lazeyras, Fabienne; Rudaz, Serge; Desmeules, Jules Alexandre; Daali, Youssef 2016
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Detection of busulfan adducts on proteins Acosta Martin, Adelina Elena; Antinori Malaspina, Paola; Uppugunduri Satyanarayana, Chakradhara Rao; Daali, Youssef; ... Lescuyer, Pierre 2016
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Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approach Marsousi, Niloufar; Samer, Caroline Flora; Fontana, Pierre; Reny, Jean-Luc; ... Daali, Youssef 2016
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Evaluation of Mutual Drug-Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method Bosilkovska Weisskopf, Marija; Samer, Caroline Flora; Deglon, Julien; Thomas, Aurélien; ... Daali, Youssef 2016
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Rivaroxaban-Induced Hemorrhage Associated with ABCB1 Genetic Defect Ing Lorenzini, Kuntheavy; Daali, Youssef; Fontana, Pierre; Desmeules, Jules Alexandre; Samer, Caroline Flora 2016
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