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Model-Informed Precision Dosing: Background, Requirements, Validation, Implementation, and Forward Trajectory of Individualizing Drug Therapy Darwich, Adam S; Polasek, Thomas M; Aronson, Jeffrey K; Ogungbenro, Kayode; ... Rostami-Hodjegan, Amin 2021
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Mesoporous Silica Nanoparticles as pH-Responsive Carrier for the Immune-Activating Drug Resiquimod Enhance the Local Immune Response in Mice Wagner, Julia; Gößl, Dorothée; Ustyanovska, Natasha; Xiong, Mengyao; ... Bourquin, Carole 2021
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Safety of the Geneva Cocktail, a Cytochrome P450 and P-Glycoprotein Phenotyping Cocktail, in Healthy Volunteers from Three Different Geographic Origins Rollason, Victoria; Mouterde, Médéric; Daali, Youssef; Čížková, Martina; ... Desmeules, Jules Alexandre 2020
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Optimized low‐dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment Zoetemelk, Marloes; Ramzy, George Mourad; Rausch, Magdalena; Kossler, Thibaud; ... Nowak-Sliwinska, Patrycja 2020
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Comparing Dried Blood Spots and Plasma Concentrations for Busulfan Therapeutic Drug Monitoring in Children Dilo, Ana; Daali, Youssef; Desmeules, Jules Alexandre; Chalandon, Yves; ... Ansari Djaberi, Marc Georges 2020
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Is pain temporary and glory forever? Detection of tramadol using dried blood spot in cycling competitions Salamin, Olivier; Garcia, Arnaud; Gonzalez Ruiz, Victor; Rossi, Francesca; ... Rudaz, Serge 2020
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Contribution of exome sequencing to the identification of genes involved in the response to clopidogrel in cardiovascular patients Fontana, Pierre; Ibberson, Mark; Stevenson, Brian; Wigger, Leonore; ... Reny, Jean-Luc 2020
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Impact of enantiomer-specific changes in pharmacokinetics between infants and adults on the target concentration of racemic ketorolac: A pooled analysis Cloesmeijer, Michael E; van Esdonk, Michiel J; Lynn, Anne M; Smits, Anne Claudine Catherine; ... Mian, Paola 2020
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Modern approaches for the phenotyping of cytochrome P450 enzymes in children Magliocco, Gaëlle; Daali, Youssef 2020
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Bioavailability of Vortioxetine After a Roux-en-Y Gastric Bypass Vandenberghe, Frederik; Gilet, Patricia; Daali, Youssef; Favre, Lucien Ody; Eap, Chin Bin 2020
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GABAergic modulation of secondary hyperalgesia: A randomized controlled 4-way crossover trial with the α2-subunit preferring GABA positive allosteric modulator, N-desmethyl-clobazam in healthy volunteers Matthey, Alain; Daali, Youssef; Curtin, François; Poncet, Antoine; ... Besson, Marie 2020
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Deep proteomics and phosphoproteomics reveal novel biological pathways perturbed by morphine, morphine-3-glucuronide and morphine-6-glucuronide in human astrocytes Dozio, Vito; Daali, Youssef; Desmeules, Jules Alexandre; Sanchez, Jean-Charles 2020
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Mixing Drugs and Genetics: A Complex Hemorrhagic Cocktail Barbolini, Laura; Terrier, Jean; Marti, Christophe; Samer, Caroline Flora; ... Reny, Jean-Luc 2020
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Evaluation of Phenotypic and Genotypic Variations of Drug Metabolising Enzymes and Transporters in Chronic Pain Patients Facing Adverse Drug Reactions or Non-Response to Analgesics: A Retrospective Study Rollason, Victoria; Lloret-linaret, Célia; Ing Lorenzini, Kuntheavy; Daali, Youssef; ... Desmeules, Jules Alexandre 2020
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Impact of acute inflammation on cytochromes P450 activity assessed by the Geneva Cocktail Lenoir, Camille; Daali, Youssef; Rollason, Victoria; Curtin, François; ... Samer, Caroline Flora 2020
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CYP450 activities before and after Roux-en-Y gastric bypass: correlation with their intestinal and liver content Lloret-Linares, Célia; Daali, Youssef; Abbara, Chadi; Carette, Claire; ... Declèves, Xavier 2019
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Physiologically-based pharmacokinetic modeling for the prediction of CYP2D6-mediated gene-drug-drug interactions Storelli, Flavia; Desmeules, Jules Alexandre; Daali, Youssef 2019
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Towards personalized antithrombotic treatments: focus on P2Y12 inhibitors and direct oral anticoagulants Terrier, Jean; Daali, Youssef; Fontana, Pierre; Csajka, Chantal; Reny, Jean-Luc 2019
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Variables of interest to predict glomerular filtration rate in preterm newborns in the first days of life Wilhelm-Bals, Alexandra Marina; Combescure, Christophe; Chehade, Hassib; Daali, Youssef; Parvex, Paloma Maria 2019
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Drug-induced expression of the RNA-binding protein HuR attenuates the adaptive response to BRAF inhibition in melanoma Merat, Rastine; Bugi, Aurore; Wrobel, Ludovic; Py, Céline; ... Liaudet, Nicolas 2019
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