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Cloning and functional characterization of mammalian homologues of the COPII component Sec23 Paccaud, Jean-Pierre; Reith, Walter; Carpentier, J. L.; Ravazzola, M.; ... Orci, Lelio 1996
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pH-independent and -dependent cleavage of proinsulin in the same secretory vesicle Orci, Lelio; Halban, Philippe A.; Perrelet, Alain; Amherdt, M.; ... Anderson, R. G. 1994
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Conversion of proinsulin to insulin occurs coordinately with acidification of maturing secretory vesicles Orci, Lelio; Ravazzola, M.; Amherdt, M.; Madsen, O.; ... Anderson, R. G. 1986
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Tris(hydroxymethyl)aminomethane inhibits the synthesis and processing of proinsulin in isolated rat pancreatic islets without affecting release of insulin stores Halban, Philippe A.; Amherdt, M.; Orci, Lelio; Renold, A. E. 1986
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Evidence for polarization of plasma membrane domains in pancreatic endocrine cells Lombardi, Tommaso; Montesano, Roberto; Wohlwend, Annelise Isabelle; Amherdt, M.; ... Orci, Lelio 1985
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Direct identification of prohormone conversion site in insulin-secreting cells Orci, Lelio; Ravazzola, M.; Amherdt, M.; Madsen, O.; ... Perrelet, A. 1985
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Proinsulin modified by analogues of arginine and lysine is degraded rapidly in pancreatic B-cells Halban, Philippe A.; Amherdt, M.; Orci, Lelio; Renold, A. E. 1984
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Nonconverted, amino acid analog-modified proinsulin stays in a Golgi-derived clathrin-coated membrane compartment Orci, Lelio; Halban, Philippe A.; Amherdt, M.; Ravazzola, M.; ... Perrelet, Alain 1984
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Insulin, not C-peptide (proinsulin), is present in crinophagic bodies of the pancreatic B-cell Orci, Lelio; Ravazzola, M.; Amherdt, M.; Yanaihara, C.; ... Perrelet, Alain 1984
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A clathrin-coated, Golgi-related compartment of the insulin secreting cell accumulates proinsulin in the presence of monensin Orci, Lelio; Halban, Philippe A.; Amherdt, M.; Ravazzola, M.; ... Perrelet, A. 1984