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 TitleAuthors / EditorsDate
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DDR1 role in fibrosis and its pharmacological targeting Moll, Solange; Desmoulière, Alexis; Moeller, Marcus J; Pache, Jean-Claude; ... Prunotto, Marco 2019
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Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancer Nowak-Sliwinska, Patrycja; Scapozza, Leonardo; Ruiz Altaba, Ariel 2019
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Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets Trofimov, Valentin; Kicka, Sébastien; Mucaria, Sabrina; Hanna, Nabil; ... Soldati, Thierry 2018
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Modeling and resistant alleles explain the selectivity of antimalarial compound 49c towards apicomplexan aspartyl proteases Mukherjee, Budhaditya; Tessaro, Francesca; Vahokoski, Juha; Kursula, Inari; ... Soldati-Favre, Dominique 2018
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Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy Gayi, Elinam; Neff, Laurence Anne; Massana Muñoz, Xènia; Ismail, Hesham; ... Scapozza, Leonardo 2018
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Autoregulation of Class II Alpha PI3K Activity by Its Lipid-Binding PX-C2 Domain Module Wang, Haibin; Lo, Wen-Ting; Vujičić Žagar, Andreja; Gulluni, Federico; ... Vadas, Oscar 2018
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Identification of novel anti-bacterial compounds from a chemically highly diverse pathways-based library using phenotypic screens in amoebae host models Kicka, Sébastien; Hanna, Nabil; Chiriano, Gianpaolo; Harrison, Christopher; ... Soldati, Thierry 2018
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Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model Ouertatani, Hajer; Kicka, Sébastien; Chiriano, Gianpaolo; Harrison, Christopher F; ... Cosson, Pierre 2017
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In silico driven design and synthesis of rhodanine derivatives as novel antibacterials targeting the enoyl reductase InhA Slepikas, Liudas; Chiriano, Gianpaolo; Perozzo, Remo; Tardy, Sébastien; ... Scapozza, Leonardo 2016
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A novel biocompatible hyaluronic acid-chitosan hybrid hydrogel for osteoarthrosis therapy Kaderli, Sema Gwendolyn; Boulocher, C; Pillet, Eric François Alfred; Watrelot-Virieux, D; ... Jordan, Olivier 2015
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A subsetofN-substituted phenothiazines inhibits NADPH oxidases Seredenin, Tamara; Chiriano, Gianpaolo; Filippova, Aleksandra; Nayernia, Zeynab; ... Jaquet, Vincent 2015
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Adrenergic antagonists restrict replication of Legionella Harrison, Christopher F; Kicka, Sébastien; Kranjc Pietrucci, Agata; Finsel, Ivo; ... Hilbi, Hubert 2015
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Amoebae-Based Screening Reveals a Novel Family of Compounds Restricting Intracellular Legionella pneumophila Harrison, Christopher F.; Chiriano, Gianpaolo; Finsel, Ivo; Manske, Christian; ... Hilbi, Hubert 2015
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Establishment and validation of whole-cell based fluorescence assays to identify anti-mycobacterial compounds using the Acanthamoeba castellanii-Mycobacterium marinum host-pathogen system Kicka, Sébastien; Trofimov, Valentin; Harrison, Christopher; Ouertatani, Hajer; ... Soldati, Thierry 2014
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Differences in Conformational Dynamics between Plasmodium falciparum and Human Hsp90 Orthologues Enable the Structure-Based Discovery of Pathogen-Selective Inhibitors Wang, Tai; Bisson, William Henry; Mäser, Pascal; Scapozza, Leonardo; Picard, Didier 2014
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Diapocynin, a Dimer of the NADPH Oxidase Inhibitor Apocynin, Reduces ROS Production and Prevents Force Loss in Eccentrically Contracting Dystrophic Muscle Ismail, Hesham; Scapozza, Leonardo; Ruegg, Urs; Dorchies, Olivier 2014
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Synthesis and in vitro evaluation of a novel radioligand for αvβ3 integrin receptor imaging: [18F]FPPA-c(RGDfK) Monaco, Alessandra; Zoete, Vincent; Alghisi, Gian Carlo; Rüegg, Curzio; ... Seimbille, Yann 2013
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The pharmaceutical biochemistry group: where pharmaceutical chemistry meets biology and drug delivery Kalia, Yogeshvar; Perozzo, Remo; Scapozza, Leonardo 2012
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Noninvasive transdermal iontophoretic delivery of biologically active human basic fibroblast growth factor Dubey, Sachin Kumar; Perozzo, Remo; Scapozza, Leonardo; Kalia, Yogeshvar 2011
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NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action Jaquet, Vincent; Marcoux, Julien; Forest, Eric; Leidal, Kevin; ... Bedard, Karen 2011
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