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Computer-assisted UHPLC–MS method development and optimization for the determination of 24 antineoplastic drugs used in hospital pharmacy Guichard, Nicolas; Fekete, Szabolcs; Guillarme, Davy; Bonnabry, Pascal; Fleury, Sandrine 2019
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Is hydrophobic interaction chromatography the most suitable technique to characterize site-specific antibody-drug conjugates? D'Atri, Valentina; Pell, Reinhard; Clarke, Adrian; Guillarme, Davy; Fekete, Szabolcs 2019
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Recent Advances in Chromatography for Pharmaceutical Analysis D'Atri, Valentina; Fekete, Szabolcs; Clarke, Adrian; Veuthey, Jean-Luc; Guillarme, Davy 2019
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Orthogonal Middle-up Approaches for Characterization of the Glycan Heterogeneity of Etanercept by Hydrophilic Interaction Chromatography Coupled to High-Resolution Mass Spectrometry D'Atri, Valentina; Nováková, Lucie; Fekete, Szabolcs; Stoll, Dwight; ... Guillarme, Davy 2019
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A scoring approach for multi-platform acquisition in metabolomics Pezzatti, Julian; Gonzalez Ruiz, Victor; Codesido Sanchez, Santiago; Gagnebin, Yoric; ... Rudaz, Serge 2019
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A generic workflow for the characterization of therapeutic monoclonal antibodies—application to daratumumab Duivelshof, Bastiaan; Fekete, Szabolcs; Guillarme, Davy; D'Atri, Valentina 2019
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Monoclonal antibody N-glycosylation profiling using capillary electrophoresis – Mass spectrometry: Assessment and method validation Giorgetti, Jérémie; D'Atri, Valentina; Canonge, Julie; Lechner, Antony; ... François, Yannis-Nicolas 2018
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Influence of connection tubing in modern size exclusionchromatography and its impact on the characterization of mAbs Fekete, Szabolcs; Guillarme, Davy 2018
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Current possibilities of liquid chromatography for the characterization of antibody-drug conjugates Bobaly, Balazs; Fleury, Sandrine; Beck, Alain; Veuthey, Jean-Luc; ... Fekete, Szabolcs 2018
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Improved separation by at-column dilution in preparative hydrophilicinteraction chromatography Jaffuel, Geoffrey; Chappuis, Laura; Guillarme, Davy; Turlings, Ted C.J.; Glauser, Gaétan 2018
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Adding a new separation dimension to MS and LC–MS: What is the utility of ion mobility spectrometry? D'Atri, Valentina; Causson, Tim; Hernandez-Alba, Oscar; Mutabazi, Aline; ... Guillarme, Davy 2018
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An Online Four-Dimensional HIC×SEC-IM×MS Methodology for Proof-of-Concept Characterization of Antibody Drug Conjugates Ehkirch, Antony; D'Atri, Valentina; Rouviere, Florent; Hernandez-Alba, Oscar; ... Cianferani, Sarah 2018
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Extending the limits of size exclusion chromatography: Simultaneousseparation of free payloads and related species from antibody drugconjugates and their aggregates Goyon, Alexandre; Sciascera, Luca; Clarke, Adrien; Guillarme, Davy; Pell, Reinhard 2018
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Systematic evaluation of matrix effects in supercritical fluid chromatography versus liquid chromatography coupled to mass spectrometry for biological samples Desfontaine, Vincent; Capetti, France4sca; Nicoli, Raul; Kuuranne, Tiia; ... Guillarme, Davy 2018
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Development of a lc–ms/ms method for the determination of isomeric glutamyl peptides in food ingredients Desfontaine, Vincent; Goyon, Alexandre; Veuthey, Jean-Luc; Charve, Joséphine; Guillarme, Davy 2018
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Characterization of an antibody-drug conjugate by hydrophilic interaction chromatography coupled to mass spectrometry D'Atri, Valentina; Fekete, Szabolcs; Stoll, Dwight; Lauber, Matthew; ... Guillarme, Davy 2018
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Natural compounds analysis using liquid and supercritical fluid chromatography hyphenated to mass spectrometry: Evaluation of a new design of atmospheric pressure ionization source Ciclet, Olivier; Barron, Denis; Bajic, Steve; Veuthey, Jean-Luc; ... Grand-Guillaume-Perrenoud, Alexandre 2018
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What are the current solutions for interfacing supercritical fluid chromatography and mass spectrometry? Guillarme, Davy; Desfontaine, Vincent; Heinisch, Sabine; Veuthey, Jean-Luc 2018
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Size Exclusion Chromatography of Protein Biopharmaceuticals: Past, Present and Future Fekete, Szabolcs; Goyon, Alexandre; Veuthey, Jean-Luc; Guillarme, Davy 2018
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Implementation of a generic liquid chromatographic methoddevelopment workflow: Application to the analysis ofphytocannabinoids and Cannabis sativa extracts Fekete, Szabolcs; Sadat-Noorbakhsh, Vida; Schelling, Cédric; Molnar, Imre; ... Veuthey, Jean-Luc 2018
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Utility of a high coverage phenyl-bonding and wide-pore superficially porous particle for the analysis of monoclonal antibodies and relatedproducts Bobaly, Balazs; Lauber, Matthew; Beck, Alain; Guillarme, Davy; Fekete, Szabolcs 2018
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Hyphenation of size exclusion chromatography to native ion mobility mass spectrometry for the analytical characterization of therapeutic antibodies and related products Ehkirch, Antony; Hernandez-Alba, Oscar; Colas, Olivier; Guillarme, Davy; Cianférani, Sarah 2018
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Development of Comprehensive Online Two-Dimensional Liquid Chromatography/Mass Spectrometry Using Hydrophilic Interaction and Reversed-Phase Separations for Rapid and Deep Profiling of Therapeutic Antibodies Stoll, Dwight R.; Harmes, David C.; Staples, Gregory O.; Potter, Oscar G.; ... Beck, Alain 2018
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New developments and possibilities of wide-pore superficially porous particle technology applied for the liquid chromatographic analysis of therapeutic proteins Bobaly, Balazs; Veuthey, Jean-Luc; Guillarme, Davy; Fekete, Szabolcs 2018
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Applicability of supercritical fluid chromatography–mass spectrometry to metabolomics. I – Optimization of separation conditions for the simultaneous analysis of hydrophilic and lipophilic substances Desfontaine, Vincent; Losacco, Gioacchino Luca; Gagnebin, Yoric; Pezzatti, Julian; ... Guillarme, Davy 2018
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Unraveling the mysteries of modern size exclusion chromatography – the way to achieve confident characterization of therapeutic proteins Goyon, Alexandre; Fekete, Szabolcs; Beck, Alain; Veuthey, Jean-Luc; Guillarme, Davy 2018
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First inter-laboratory study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities Dispas, Amandine; Marini, Roland; Desfontaine, Vincent; Veuthey, Jean-Luc; ... Hubert, Philippe 2018
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Apparent efficiency of serially coupled columns in isocratic and gradient elution modes Fekete, Szabolcs; Codesido Sanchez, Santiago; Rudaz, Serge; Guillarme, Davy; Horváth, Krisztián 2018
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Editorial for the special issue entitled “supercritical fluid chromatography – mass spectrometry” Guillarme, Davy; Veuthey, Jean-Luc 2018
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An attempt to characterize the human Chorionic Gonadotropin protein by reversed phase liquid chromatography coupled with high-resolution mass spectrometry at the intact level Camperi, Julien; Combes, Audrey; Guibourdenche, Jean; Guillarme, Davy; ... Delaunay, Nathalie 2018
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High-resolution separation of monoclonal antibodies mixtures and their charge variants by an alternative and generic CZE method Goyon, Alexandre; Francois, Yannis Nicolas; Colas, Olivier; Beck, Alain; ... Guillarme, Davy 2018
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Tips, Tricks, and Troubleshooting for Separations of Biomolecules, Part I: Contemporary Reversed-Phase Protein Separations Fekete, Szabolcs; Guillarme, Davy; Stoll, Dwight R. 2018
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Tips, Tricks, and Troubleshooting for Separations of Biomolecules, Part 1: Contemporary Reversed-Phase Protein Separations Fekete, Szabolcs; Guillarme, Davy; Stoll, Dwight R. 2018
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Protocols for the analytical characterization of therapeutic monoclonal antibodies. III – Denaturing chromatographic techniques hyphenated to mass spectrometry D'Atri, Valentina; Goyon, Alexandre; Bobaly, Balazs; Beck, Alain; ... Guillarme, Davy 2018
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Characterizing various monoclonal antibodies with milder reversed phase chromatography conditions Bobaly, Balazs; D'Atri, Valentina; Lauber, Matthew; Beck, Alain; ... Fekete, Szabolcs 2018
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HPLC Teaching Assistant: A New Tool for Learning and Teaching Liquid Chromatography, Part 1 Guillarme, Davy; Veuthey, Jean-Luc 2017
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Optimization of non-linear gradient in hydrophobic interaction chromatography for the analytical characterization of antibody-drug conjugates Bobaly, Balazs; Randazzo, Giuseppe Marco; Rudaz, Serge; Guillarme, Davy; Fekete, Szabolcs 2017
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The importance of system band broadening in modern size exclusion chromatography Goyon, Alexandre; Guillarme, Davy; Fekete, Szabolcs 2017
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Separation of antibody drug conjugate species by RPLC: A genericmethod development approach Fekete, Szabolcs; Molnar, Imre; Guillarme, Davy 2017
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Development of a fast workflow to screen the charge variants of therapeutic antibodies Wagner-Rousset, Elsa; Fekete, Szabolcs; Morel-Chevillet, Laura; Colas, Olivier; ... Beck, Alain 2017
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Hyphenated Detectors: Mass Spectrometry Desfontaine, Vincent; Veuthey, Jean-Luc; Guillarme, Davy 2017
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Optimized selection of liquid chromatography conditions for widerange analysis of natural compounds Periat, Aurélie Claudine; Guillarme, Davy; Veuthey, Jean-Luc; Boccard, Julien; ... Grand-Guillaume Perrenoud, Alexandre 2017
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Antineoplastic drugs and their analysis: a state of the art review Guichard, Nicolas; Guillarme, Davy; Bonnabry, Pascal; Fleury-Souverain, Sandrine 2017
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Alternative Strategies to Reversed-Phase Liquid Chromatography for the Analysis of Pharmaceutical Compounds Guillarme, Davy; Veuthey, Jean-Luc 2017
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Achievable separation performance and analysis time in current liquid chromatographic practice for monoclonal antibody separations Fekete, Szabolcs; Veuthey, Jean-Luc; Guillarme, Davy 2017
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A systematic investigation of sample diluents in modern supercritical fluid chromatography Desfontaine, Vincent; Tarafder, Abhijit; Hill, Jason; Fairchild, Jacob; ... Guillarme, Davy 2017
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Computer-Assisted Method Development for Small and Large Molecules Fekete, Szabolcs; Kormàni, Robert; Guillarme, Davy 2017
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UHPLC, Part 2: Benefits Dong, Michael W.; Guillarme, Davy 2017
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Comprehensive study on the effects of sodium and potassiumadditives in size exclusion chromatographic separations of proteinbiopharmaceuticals Goyon, Alexandre; Beck, Alain; Veuthey, Jean-Luc; Guillarme, Davy; Fekete, Szabolcs 2017
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UHPLC, Part II: Benefits Dong, Michael W.; Guillarme, Davy 2017
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