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An Integrative Multi-Omics Workflow to Address Multifactorial Toxicology Experiments Gonzalez Ruiz, Victor; Schvartz, Domitille; Sandstrom Von Tobel, Jenny; Pezzatti, Julian; ... Rudaz, Serge 2019
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A scoring approach for multi-platform acquisition in metabolomics Pezzatti, Julian; Gonzalez Ruiz, Victor; Codesido Sanchez, Santiago; Gagnebin, Yoric; ... Rudaz, Serge 2019
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Steroid profiles in both blood serum and seminal plasma are not correlated and do not reflect sperm quality: Study on the male reproductive health of fifty young Swiss men Zufferey, Fanny; Rahban, Rita; Garcia, Arnaud; Gagnebin, Yoric; ... Rossier, Michel F 2018
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Metabolomics in chronic kidney disease: Strategies for extended metabolome coverage Gagnebin, Yoric; Boccard, Julien; Ponte, Bélen; Rudaz, Serge 2018
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Dynamics of Metabolite Induction in Fungal Co-cultures by Metabolomics at Both Volatile and Non-volatile Levels Azzollini, Antonio; Boggia, Lorenzo; Boccard, Julien; Sgorbini, Barbara; ... Wolfender, Jean-Luc 2018
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Optimized selection of liquid chromatography conditions for widerange analysis of natural compounds Periat, Aurélie Claudine; Guillarme, Davy; Veuthey, Jean-Luc; Boccard, Julien; ... Grand-Guillaume Perrenoud, Alexandre 2017
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Indirect quantitative structure-retention relationship for steroid identification: A chemometric challenge at "Chimiométrie 2016" Randazzo, Giuseppe Marco; Vigneau, Evelyne; Courcoux, Philippe; Harrouet, Corentin; ... Rudaz, Serge 2017
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Steroid profiling in H295R cells to identify chemicals potentially disrupting the production of adrenal steroids Strajhar, Petra; Tonoli, David; Jeanneret, Fabienne; Imhof ., Raphaella M; ... Odermatt, Alex 2017
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Metabolomic analysis of urine samples by UHPLC-QTOF-MS: Impact of normalization strategies Gagnebin, Yoric; Tonoli, David; Lescuyer, Pierre; Ponte, Belen; ... Rudaz, Serge 2017
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Systematic evaluation of matrix effects in hydrophilic interaction chromatography versus reversed phase liquid chromatography coupled to mass spectrometry Periat, Aurélie Claudine; Kohler, Isabelle; Thomas, Aurélien; Nicoli, Raul; ... Guillarme, Davy 2016
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Prediction of retention time in reversed-phase liquid chromatography as a tool for steroid identification Randazzo, Giuseppe Marco; Tonoli, David; Hambye, Stéphanie; Guillarme, Davy; ... Rudaz, Serge 2016
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Evaluation and identification of dioxin exposure biomarkers in human urine by high-resolution metabolomics, multivariate analysis and in vitro synthesis Jeanneret, Fabienne; Tonoli, David; Hochstrasser, Denis; Saurat, Jean-Hilaire; ... Rudaz, Serge 2016
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Ultra-high performance supercritical fluid chromatography coupled with quadrupole-time-of-flight mass spectrometry as a performingtool for bioactive analysis Grand-Guillaume-Perrenoud, Alexandre; Guillarme, Davy; Boccard, Julien; Veuthey, Jean-Luc; ... Moco, Sofia 2016
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Exploring Omics data from designed experiments using analysis of variance multiblock Orthogonal Partial Least Squares Boccard, Julien; Rudaz, Serge 2016
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High-throughput identification of monoclonal antibodies after compounding by UV spectroscopy coupled to chemometrics analysis Jacoulet, Emmanuel; Boccard, Julien; Taverna, Myriam; Santos Azevedos, Andrea; ... Smadja, Claire 2016
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Longitudinal monitoring of endogenous steroids in human serum by UHPLC-MS/MS as a tool to detect testosterone abuse in sports Ponzetto, Federico; Mehl, Florence; Boccard, Julien; Baume, Norbert; ... Nicoli, Raul 2016
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Evaluation of steroidomics by liquid chromatography hyphenated to mass spectrometry as a powerful analytical strategy for measuring human steroid perturbations Jeanneret, Fabienne; Tonoli, David; Rossier, Michel; Saugy, Martial; ... Rudaz, Serge 2016
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Statistical Correlations between HPLC Activity-Based Profiling Results and NMR/MS Microfraction Data to Deconvolute Bioactive Compounds in Mixtures Bertrand, Samuel; Azzollini, Antonio; Nievergelt-Meier, Andreas; Boccard, Julien; ... Wolfender, Jean-Luc 2016
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Steroidomic Footprinting Based on Ultra-High Performance Liquid Chromatography Coupled with Qualitative and Quantitative High- Resolution Mass Spectrometry for the Evaluation of Endocrine Disrupting Chemicals in H295R Cells Tonoli, David; Furstenberger, Cornelia; Boccard, Julien; Hochstrasser, Denis; ... Rudaz, Serge 2015
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Integrating metabolomic data from multiple analytical platforms for a comprehensive characterisation of lemon essential oils Mehl, Florence; Marti, Guillaume; Merle, Philippe; Delort, Estelle; ... Boccard, Julien 2015
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Differentiation of lemon essential oil based on volatile and non-volatile fractions with various analytical techniques: a metabolomic approach Mehl, Florence; Marti, Guillaume; Boccard, Julien; Debrus, Benjamin; ... Rudaz, Serge 2014
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Comprehensive profiling and marker identification in non-volatile citrus oil residues by mass spectrometry and nuclear magnetic resonance Marti, Guillaume; Boccard, Julien; Mehl, Florence; Debrus, Benjamin; ... Wolfender, Jean-Luc 2014
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Untargeted profiling of urinary steroid metabolites after testosterone ingestion: opening new perspectives for antidoping testing Boccard, Julien; Badoud, Flavia; Jan, Nicolas; Nicoli, Raul; ... Saugy, Martial 2014
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Systematic comparison of sensitivity between hydrophilic interaction liquid chromatography and reversed phase liquid chromatography coupled with mass spectrometry Periat, Aurélie Claudine; Boccard, Julien; Veuthey, Jean-Luc; Rudaz, Serge; Guillarme, Davy 2013
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Human urinary biomarkers of dioxin exposure: Analysis by metabolomics and biologically driven data dimensionality reduction Jeanneret, Fabienne; Boccard, Julien; Badoud, Flavia; Sorg, Olivier; ... Rudaz, Serge 2013
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Analysis of basic compounds by supercritical fluid chromatography: Attempts to improve peak shape and maintain mass spectrometry compatibility Grand-Guillaume-Perrenoud, Alexandre; Boccard, Julien; Veuthey, Jean-Luc; Guillarme, Davy 2012
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New Insights in Pharmaceutical Analysis Guillarme, Davy; Schappler, Julie; Boccard, Julien; Veuthey, Jean-Luc; Rudaz, Serge 2012
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Method development for pharmaceutics: Some solutions for tuning selectivity in reversed phase and hydrophilic interaction liquid chromatography Ruta, Josephine; Boccard, Julien; Cabooter, Deirdre; Rudaz, Serge; ... Guillarme, Davy 2012
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Analyse métabolomique dans l'urine par UHPLC-QTOF-MSE : profilage des stéroïdes appliqué au dépistage antidopage Boccard, Julien; Badoud, Flavia; Grata, Elia; Ouertani, Samia; ... Rudaz, Serge 2012
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A steroidomic approach for biomarkers discovery in doping control Boccard, Julien; Badoud, Flavia; Grata, Elia; Ouertani, Samia; ... Rudaz, Serge 2011
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Analytical aspects in doping control: Challenges and perspectives Badoud, Flavia; Guillarme, Davy; Boccard, Julien; Grata, Elia; ... Veuthey, Jean-Luc 2011
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Quantification of glucuronidated and sulfated steroids in human urine by ultra-high pressure liquid chromatography quadrupole time-of-flight mass spectrometry Badoud, Flavia; Grata, Elia; Boccard, Julien; Guillarme, Davy; ... Saugy, Martial 2011
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Standard machine learning algorithms applied to UPLC-TOF/MS metabolic fingerprinting for the discovery of wound biomarkers in Arabidopsis thaliana Boccard, Julien; Kalousis, Alexandros; Hilario, Mélanie; Lantéri, Pierre; ... Rudaz, Serge 2010
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Mass spectrometry-based metabolomics oriented by correlation analysis for wound-induced molecule discovery: identification of a novel jasmonate glucoside Glauser, Gaétan; Boccard, Julien; Rudaz, Serge; Wolfender, Jean-Luc 2010
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Knowledge discovery in metabolomics: An overview of MS data handling Boccard, Julien; Veuthey, Jean-Luc; Rudaz, Serge 2010
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MS-based Plant Metabolomic Approaches for Biomarker Discovery Wolfender, Jean-Luc; Glauser, Gaétan; Boccard, Julien; Rudaz, Serge 2009
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Metabolite profiling of plant extracts by ultra-high-pressure liquid chromatography at elevated temperature coupled to time-of-flight mass spectrometry Grata, Elia; Guillarme, Davy; Glauser, Gaétan; Boccard, Julien; ... Wolfender, Jean-Luc 2009
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Breast cancer resistance protein (BCRP/ABCG2): new inhibitors and QSAR studies by a 3D linear solvation energy approach Nicolle, Edwige; Boccard, Julien; Guilet, David; Dijoux-Franca, Marie-Geneviève; ... Boumendjel, Ahcène 2009
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A 3D linear solvation energy model to quantify the affinity of flavonoid derivatives toward P-glycoprotein Boccard, Julien; Bajot, Fania; Di Pietro, Attilio; Rudaz, Serge; ... Carrupt, Pierre-Alain 2009
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Knowledge discovery in pharmaceutical sciences, from metabolomics to molecular modelling Boccard, Julien 2009
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Highlights of Analytical Chemistry in Switzerland: Plant Metabolomics – Strategies for Biomarker Detection, Isolation, and Identification Grata, Elia; Boccard, Julien; Glauser, Gaétan; Guillarme, Davy; ... Rudaz, Serge 2008
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UPLC-TOF-MS for plant metabolomics. A powerful tool for discriminating stress states in plants and detecting low level wound-biomarkers Glauser, Gaétan; Grata, Elia; Boccard, Julien; Marsden-Edwards, E.; ... Wolfender, Jean-Luc 2008
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Optimized liquid chromatography-mass spectrometry approach for the isolation of minor stress biomarkers in plant extracts and their identification by capillary nuclear magnetic resonance Glauser, Gaétan; Guillarme, Davy; Grata, Elia; Boccard, Julien; ... Wolfender, Jean-Luc 2008
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Antimitotic and antiproliferative activities of chalcones: forward structure-activity relationship Boumendjel, Ahcène; Boccard, Julien; Carrupt, Pierre-Alain; Nicolle, Edwige; ... Dumontet, Charles 2008
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UPLC-TOF-MS for plant metabolomics: a sequential approach for wound marker analysis in Arabidopsis thaliana Grata, Elia; Boccard, Julien; Guillarme, Davy; Glauser, Gaétan; ... Rudaz, Serge 2008
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Multivariate data analysis of rapid LC-TOF/MS experiments from Arabidopsis thaliana stressed by wounding Boccard, Julien; Grata, Elia; Thiocone, Aly; Gauvrit, Jean-Yves; ... Rudaz, Serge 2007
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Development of a two-step screening ESI-TOF-MS method for rapid determination of significant stress-induced metabolome modifications in plant leaf extracts: the wound response in Arabidopsis thaliana as a case study Grata, Elia; Boccard, Julien; Glauser, Gaétan; Carrupt, Pierre-Alain; ... Rudaz, Serge 2007
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Synergy at the 'Ecole de Pharmacie Geneve-Lausannel': Methodology developments for the treatment of complex metabolomic datasets with data mining Thiocone, Aly; Grata, Elia; Boccard, Julien; Carrupt, Pierre-Alain; ... Wolfender, Jean-Luc 2005
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CD40-CD40 ligand disruption does not prevent hyperoxia-induced injury Barazzone, Constance; Donati, Yves Richard; Boccard, Julien; Rochat, Anne-Françoise; ... Piguet, Pierre-François 2002