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Tumor Suppressor PTEN Regulates Negatively Sertoli Cell Proliferation, Testis Size, and Sperm Production In Vivo Neirijnck, Yasmine; Kuhne, Françoise; Mayere, Chloé; Pavlova, Ekaterina; ... Nef, Serge 2019
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Bi-allelic Mutations in ARMC2 Lead to Severe Astheno-Teratozoospermia Due to Sperm Flagellum Malformations in Humans and Mice Coutton, Charles; Martinez, Guillaume; Kherraf, Zine-Eddine; Amiri-Yekta, Amir; ... Ray, Pierre F 2019
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The ReproGenomics Viewer: a multi-omics and cross-species resource compatible with single-cell studies for the reproductive science community Darde, Thomas A; Lecluze, Estelle; Lardenois, Aurélie; Stevant, Isabelle; ... Chalmel, Frédéric 2019
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Dissecting Cell Lineage Specification and Sex Fate Determination in Gonadal Somatic Cells Using Single-Cell Transcriptomics Stevant, Isabelle; Kuhne, Françoise; Greenfield, Andy; Chaboissier, Marie-Christine; ... Nef, Serge 2019
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Genetic Control of Gonadal Sex Determination and Development Stevant, Isabelle; Nef, Serge 2019
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Semen quality of young men in Switzerland: a nationwide cross‐sectional population‐based study Rahban, Rita; Priskorn, L.; Senn, Alfred Paul; Stettler, Eric; ... Nef, Serge 2019
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Genetic resistance to DEHP-induced transgenerational endocrine disruption Stenz, Ludwig; Rahban, Rita; Prados, Julien; Nef, Serge; Giacobino, Ariane 2019
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Creation of knock out and knock in mice by CRISPR/Cas9 to validate candidate genes for human male infertility, interest, difficulties and feasibility Kherraf, Zine-Eddine; Conne, Béatrice; Amiri-Yekta, Amir; Kent, Marie Christou; ... Ray, Pierre F 2018
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Steroid profiles in both blood serum and seminal plasma are not correlated and do not reflect sperm quality: Study on the male reproductive health of fifty young Swiss men Zufferey, Fanny; Rahban, Rita; Garcia, Arnaud; Gagnebin, Yoric; ... Rossier, Michel F 2018
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PATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice Christou-Kent, Marie; Kherraf, Zine-Eddine; Amiri-Yekta, Amir; Le Blévec, Emilie; ... Arnoult, Christophe 2018
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Insulin/IGF1 signalling regulates the mitochondrial biogenesis markers in steroidogenic cells of prepubertal testis, but not ovary Radovic, Sava M; Starovlah, Isidora M; Cap, Ivan; Miljkovic, Dejan; ... Andric, Silvana A 2018
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The impact of new technologies in our understanding of testis formation and function Nef, Serge; Wilhelm, Dagmar 2018
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A Case of Two Sisters Suffering from 46,XY Gonadal Dysgenesis and Carrying a Mutation of a Novel Candidate Sex-Determining Gene STARD8 on the X Chromosome Ilaslan, Erkut; Calvel, Pierre; Nowak, Dominika; Szarras-Czapnik, Maria; ... Kusz-Zamelczyk, Kamila 2018
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Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human Coutton, Charles; Conne, Béatrice; Escoffier Breancon, Jessica; Nef, Serge 2018
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A brief history of sex determination Stevant, Isabelle; Papaioannou, Marilena D; Nef, Serge 2018
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Single cell transcriptome sequencing: A new approach for the study of mammalian sex determination Stevant, Isabelle; Nef, Serge 2018
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Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells Neirijnck, Yasmine; Calvel, Pierre; Kilcoyne, Karen R; Kuhne, Françoise; ... Nef, Serge 2018
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NRG1 signalling regulates the establishment of Sertoli cell stock in the mouse testis Gregoire, Elodie P; Stevant, Isabelle; Chassot, Anne-Amandine; Martin, Luc; ... Chaboissier, Marie-Christine 2018
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ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling Harris, Abigail; Siggers, Pam; Corrochano, Silvia; Warr, Nick; ... Greenfield, Andy 2018
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Deciphering Cell Lineage Specification during Male Sex Determination with Single-Cell RNA Sequencing Stevant, Isabelle; Neirijnck, Yasmine; Borel, Christelle; Escoffier Breancon, Jessica; ... Nef, Serge 2018
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Testicular Dysgenesis Syndrome and Long-Lasting Epigenetic Silencing of Mouse Sperm Genes Involved in the Reproductive System after Prenatal Exposure to DEHP. Stenz, Ludwig; Escoffier Breancon, Jessica; Rahban, Rita; Nef, Serge; Giacobino, Ariane 2017
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Sertoli Cell Number Defines and Predicts Germ and Leydig Cell Population Sizes in the Adult Mouse Testis Rebourcet, Diane; Darbey, Annalucia; Monteiro, Ana; Soffientini, Ugo; ... O'Shaughnessy, Peter J 2017
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SPINK2 deficiency causes infertility by inducing sperm defects in heterozygotes and azoospermia in homozygotes Kherraf, Zine-Eddine; Christou-Kent, Marie; Karaouzene, Thomas; Amiri-Yekta, Amir; ... Arnoult, Christophe 2017
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MPC1-like Is a Placental Mammal-specific Mitochondrial Pyruvate Carrier Subunit Expressed in Postmeiotic Male Germ Cells Vanderperre, Benoît; Cermakova, Kristina; Escoffier Breancon, Jessica; Kaba, Mayis; ... Martinou, Jean-Claude 2016
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Homozygous mutation of PLCZ1 leads to defective human oocyte activation and infertility that is not rescued by the WW-binding protein PAWP. Escoffier Breancon, Jessica; Lee, Hoi Chang; Yassine, Sandra; Zouari, Raoudha; ... Arnoult, Christophe 2016
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Sequential transcriptional waves direct the differentiation of newborn neurons in the mouse neocortex Telley, Ludovic; Govindan, Subashika; Prados, Julien; Stevant, Isabelle; ... Jabaudon, Denis 2016
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Stress-activated miR-21/miR-21* in hepatocytes promotes lipid and glucose metabolic disorders associated with high-fat diet consumption Calo, Nicolas Virgile; Ramadori, Pierluigi; Sobolewski, Cyril; Romero, Yannick; ... Foti, Michelangelo 2016
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Research resource: the dynamic transcriptional profile of sertoli cells during the progression of spermatogenesis Zimmermann, Céline; Stevant, Isabelle; Borel, Christelle; Conne, Béatrice; ... Nef, Serge 2015
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DICER Regulates the Formation and Maintenance of Cell-Cell Junctions in the Mouse Seminiferous Epithelium Korhonen, Hanna Maria; Yadav, Ram Prakash; Da Ros, Matteo; Chalmel, Frédéric; ... Kotaja, Noora 2015
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A Case of Wiedemann-Steiner Syndrome Associated with a 46,XY Disorder of Sexual Development and Gonadal Dysgenesis Calvel, Pierre; Kusz-Zamelczyk, Kamila; Makrythanasis, Periklis; Janecki, Damian; ... Jaruzelska, Jadwiga 2015
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Autocrine Action of IGF2 Regulates Adult β-Cell Mass and Function Modi, Honey; Jacovetti, Cecile; Tarussio, David; Metref, Salima; ... Thorens, Bernard 2015
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Loss of Function Mutation in the Palmitoyl-Transferase HHAT Leads to Syndromic 46,XY Disorder of Sex Development by Impeding Hedgehog Protein Palmitoylation and Signaling Callier, Patrick; Calvel, Pierre; Matevossian, Armine; Makrythanasis, Periklis; ... Nef, Serge 2014
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Sertoli cells control peritubular myoid cell fate and support adult Leydig cell development in the prepubertal testis Rebourcet, D.; O'Shaughnessy, P. J.; Pitetti, Jean-Luc; Monteiro, A.; ... Smith, L. B. 2014
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The emerging role of insulin-like growth factors in testis development and function Griffeth, Richard J; Bianda, Vanessa; Nef, Serge 2014
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Germ cell-specific targeting of DICER or DGCR8 reveals a novel role for endo-siRNAs in the progression of mammalian spermatogenesis and male fertility Zimmermann, Céline; Romero, Yannick; Warnefors, Maria; Bilican, Adem; ... Nef, Serge 2014
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An Essential Role for Insulin and IGF1 Receptors in Regulating Sertoli Cell Proliferation, Testis Size, and FSH Action in Mice Pitetti, Jean-Luc; Calvel, Pierre; Zimmermann, Céline; Conne, Béatrice; ... Nef, Serge 2013
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Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice Pitetti, Jean-Luc; Calvel, Pierre; Romero, Yannick; Conne, Béatrice; ... Nef, Serge 2013
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Cellular source and mechanisms of high transcriptome complexity in the mammalian testis Soumillon, Magali; Necsulea, Anamaria; Weier, Manuela; Brawand, David; ... Kaessmann, Henrik 2013
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DNA Methylation Profiling of the Fibrinogen Gene Landscape in Human Cells and during Mouse and Zebrafish Development Vorjohann, Silja; Pitetti, Jean-Luc; Nef, Serge; Gonelle-Gispert, Carmen; ... Neerman Arbez, Marguerite 2013
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The Glucocorticoid-induced leucine zipper (GILZ) Is essential for spermatogonial survival and spermatogenesis Romero, Yannick; Vuandaba, Mavunza Livia; Suarez, P; Grey, C; ... Nef, Serge 2012
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Petits ARN non condants et spermatogenèse Romero, Yannick; Calvel, Pierre; Nef, Serge 2012
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Short-term treatment with bisphenol-A leads to metabolic abnormalities in adult male mice Batista, Thiago M; Alonso-Magdalena, Paloma; Vieira, Elaine; Amaral, Maria Esmeria C; ... Nadal, Angel 2012
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Soy, phytoestrogens and their impact on reproductive health Cederroth, Christopher Robin; Zimmermann, Céline; Nef, Serge 2012
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Prevention of Diabetes in db/db Mice by Dietary Soy Is Independent of Isoflavone Levels Zimmermann, Céline; Cederroth, Christopher R; Bourgoin, Lucie; Foti, Michelangelo; Nef, Serge 2012
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Dicer1 depletion in male germ cells leads to infertility due to cumulative meiotic and spermiogenic defects Romero, Yannick; Meikar, Oliver; Papaioannou, Marilena D; Conne, Béatrice; ... Nef, Serge 2011
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Beta- and gamma-cytoplasmic actins are required for meiosis in mouse oocytes Brockmann, Céline Denise; Huarte, Joachim; Dugina, Vera; Challet, Ludivine; ... Vassalli, Jean-Dominique 2011
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Hematopoietic prostaglandin D synthase (H-Pgds) is expressed in the early embryonic gonad and participates to the initial nuclear translocation of the SOX9 protein Moniot, Brigitte; Farhat, Andalib; Aritake, Kosuke; Declosmenil, Faustine; ... Boizet-Bonhoure, Brigitte 2011
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Dicer is required for haploid male germ cell differentiation in mice Korhonen, Hanna M; Meikar, Oliver; Yadav, Ram Prakash; Papaioannou, Marilena D; ... Kotaja, Noora 2011
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Loss of Dicer in Sertoli cells has a major impact on the testicular proteome of mice Papaioannou, Marilena D; Lagarrigue, Mélanie; Vejnar, Charles; Rolland, Antoine D; ... Nef, Serge 2011
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The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {beta}-cells against stress-induced apoptosis Baquie, Mathurin; St-Onge, Luc; Kerr-Conte, Julie; Cobo-Vuilleumier, Nadia; ... Gauthier, Benoît 2011
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