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Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stress Kirkpatrick, Clare; Wiederkehr, Andreas; Baquie, Mathurin; Akhmedov, Dmitry; ... Wollheim, Claes 2011
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Immunohistochemical assessment of Pax8 expression during pancreatic islet development and in human neuroendocrine tumors Lorenzo, Petra I; Jimenez Moreno, Carmen M; Delgado, Irene; Cobo-Vuilleumier, Nadia; ... Gauthier, Benoît 2011
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The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {beta}-cells against stress-induced apoptosis Baquie, Mathurin; St-Onge, Luc; Kerr-Conte, Julie; Cobo-Vuilleumier, Nadia; ... Gauthier, Benoît 2011
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In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice Hu He, Kai Hui; Lorenzo, Petra I; Brun, Thierry; Jimenez Moreno, Carmen M; ... Gauthier, Benoît 2011
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PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression Gauthier, Benoît; Wiederkehr, Andreas; Baquie, Mathurin; Dai, Chunhua; ... Wollheim, Claes 2009
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Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression Serre Beinier, Véronique; Bosco, Domenico; Zulianello, Laurence; Charollais, Anne; ... Meda, Paolo 2009
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Synaptotagmin VII splice variants alpha, beta, and delta are expressed in pancreatic beta-cells and regulate insulin exocytosis Gauthier, Benoît; Duhamel, Dominique L.; Iezzi, Mariella; Theander, Sten; ... Wollheim, Claes 2008
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The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1 Brun, Thierry; He, Kai Hui Hu; Lupi, Roberto; Boehm, Bernhard; ... Gauthier, Benoît 2008
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A focus on the role of Pax4 in mature pancreatic islet beta-cell expansion and survival in health and disease Brun, Thierry; Gauthier, Benoît 2008
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Synaptotagmins bind calcium to release insulin Gauthier, Benoît; Wollheim, Claes 2008
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A new conditional mouse mutant reveals specific expression and functions of connexin36 in neurons and pancreatic beta-cells Wellershaus, Kerstin; Degen, Joachim; Deuchars, Jim; Theis, Martin; ... Willecke, Klaus 2008
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Pancreatic insulin content regulation by the estrogen receptor ER alpha Alonso-Magdalena, Paloma; Ropero, Ana B.; Carrera, M Pilar; Cederroth, Christopher; ... Nadal, Angel 2008
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The transcription factor PAX4 acts as a survival gene in INS-1E insulinoma cells Brun, Thierry; Duhamel, Dominique; Hu He, Kaihui; Wollheim, Claes; Gauthier, Benoît 2007
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Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets Maedler, Kathrin; Schumann, Desiree M; Sauter, Nadine; Ellingsgaard, Helga; ... Donath, Marc Y 2006
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Characterization of two distinct liver progenitor cell subpopulations of hematopoietic and hepatic origins Corcelle, Véronique; Stieger, B; Gjinovci, Aslan; Wollheim, Claes; Gauthier, Benoît 2006
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Micro-ARN: ribo-régulateurs de l'homéostasie du glucose Gauthier, Benoît; Wollheim, Claes 2006
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MicroRNAs: 'ribo-regulators' of glucose homeostasis Gauthier, Benoît; Wollheim, Claes 2006
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The diabetes-linked transcription factor PAX4 promotes {beta}-cell proliferation and survival in rat and human islets Brun, Thierry; Franklin, Isobel; St-Onge, Luc; Biason-Lauber, Anna; ... Gauthier, Benoît 2004
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Foxa2 (HNF3beta) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin release Wang, Haiyan; Gauthier, Benoît; Hagenfeldt-Johansson, Kerstin Arlette; Iezzi-Bakhtiari, Mariella; Wollheim, Claes 2002
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Hepatic nuclear factor-3 (HNF-3 or Foxa2) regulates glucagon gene transcription by binding to the G1 and G2 promoter elements Gauthier, Benoît; Schwitzgebel Luscher, Valérie; Zaiko, Maia; Mamin, Aline; ... Philippe, Jacques 2002