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A case report of cholinergic rebound syndrome following abrupt low-dose clozapine discontinuation in a patient with type I bipolar affective disorder Galova, Andréa; Berney, Patricia Elisabeth; Desmeules, Jules Alexandre; Sergentanis, Ioannis; Besson, Marie 2019
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Safety issues of pharmacological acute pain treatment in children Rodieux, Frédérique; Piguet, Valérie; Desmeules, Jules Alexandre; Samer, Caroline Flora 2019
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Physiologically-based pharmacokinetic modeling for the prediction of CYP2D6-mediated gene-drug-drug interactions Storelli, Flavia; Desmeules, Jules Alexandre; Daali, Youssef 2019
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Phenotyping of human CYP450 enzymes by endobiotics: current knowledge and methodological approaches Magliocco, Gaëlle; Thomas, Aurélien; Desmeules, Jules Alexandre; Daali, Youssef 2019
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When the Safe Alternative Is Not That Safe: Tramadol Prescribing in Children Rodieux, Frédérique; Vutskits, Laszlo; Posfay Barbe, Clara; Habre, Walid; ... Samer, Caroline Flora 2018
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Prescription des opioïdes chez les patients vulnérables : les enfants et les personnes âgées. Recommandations pratiques Rodieux, Frédérique; Lloret-Linares, Célia; Piguet, Valérie; Desmeules, Jules Alexandre 2018
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Gestion de la douleur aiguë chez les patients sous traitements de substitution aux opioïdes Manguzzi, Elena; Wainstein, Laura; Desmeules, Jules Alexandre; Broers, Barbara 2018
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Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software Marsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef 2018
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Genotype-sensitive reversible and time-dependent CYP2D6 inhibition in human liver microsomes Storelli, Flavia; Desmeules, Jules Alexandre; Daali, Youssef 2018
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Severe and persistent morphine-induced respiratory depression associated with ATP-Binding Cassette Subfamily B Member 1 and catechol-O-methyltransferase genetic defects: A case report Aebischer, Gaspard; Ing Lorenzini, Kuntheavy; Tomala, Simon; Desmeules, Jules Alexandre; ... Samer, Caroline Flora 2018
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Complex Drug-Drug-Gene-Disease Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical Perspectives Storelli, Flavia; Samer, Caroline Flora; Reny, Jean-Luc; Desmeules, Jules Alexandre; Daali, Youssef 2018
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Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites Marsousi, Niloufar; Daali, Youssef; Fontana, Pierre; Reny, Jean-Luc; ... Samer, Caroline Flora 2018
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Phenotypic Assessment of Drug Metabolic Pathways and P-Glycoprotein in Patients Treated With Antidepressants in an Ambulatory Setting Lloret-Linares, Célia; Bosilkovska Weisskopf, Marija; Daali, Youssef; Gex-Fabry, Marianne; ... Besson, Marie 2018
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PIM-Check: development of an international prescription-screening checklist designed by a Delphi method for internal medicine patients Desnoyer, Aude; Blanc, Anne-Laure; Pourcher, Valérie; Besson, Marie; ... Guignard, Bertrand 2017
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"Late" Withdrawal Syndrome after Carbamazepine In Utero Exposure in a CYP2C9 Slow Metabolizer Newborn Passia, Evangelia; Rock, Nathalie; Pfister, Riccardo; Ing Lorenzini, Kuntheavy; ... Samer, Caroline Flora 2017
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Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective study Lloret-Linares, Célia; Rollason Gumprecht, Victoria; Ing Lorenzini, Kuntheavy; Samer, Caroline Flora; ... Besson, Marie 2017
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Hepatocyte Concentrations of Indocyanin Green (ICG) Reflects Transfer Rates Across Membrane Transporters Cusin, Fabien; Azevedo, Liliana; Bonnaventure, Pierre; Desmeules, Jules Alexandre; ... Pastor, Catherine 2017
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Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferases Romand, Stéphanie Anne; Spaggiari, Dany; Marsousi, Niloufar; Samer, Caroline Flora; ... Rudaz, Serge 2017
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Usefulness of PBPK Modeling in Incorporation of Clinical Conditions in Personalized Medicine Marsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef 2017
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Impact of CYP2D6 functional allelic variations on phenoconversion and drug-drug interactions Storelli, Flavia; Matthey, Alain; Lenglet, Sébastien; Thomas, Aurélien; ... Daali, Youssef 2017
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Exploring venlafaxine pharmacokinetic variability with a phenotyping approach, a multicentric french-swiss study (MARVEL study) Lloret-Linares, Célia; Daali, Youssef; Chevret, Sylvie; Nieto, Isabelle; ... Bellivier, Frank 2017
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Meta-xylene: identification of a new antigenic entity in hypersensitivity reactions to local anesthetics Ing Lorenzini, Kuntheavy; Gay-Crosier Chabry, Fabienne; Piguet, Claude; Desmeules, Jules Alexandre 2016
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Prescriptions médicamenteuses potentiellement inappropriées en gériatrie: quels outils utiliser pour les détecter? Desnoyer, Aude; Guignard, Bertrand; Lang, Pierre-Olivier; Desmeules, Jules Alexandre; ... Bonnabry, Pascal 2016
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Le coût, ce n’est pas tout…à propos des médicaments génériques Piguet, Valérie; D'Incau, Stéphanie; Besson, Marie; Desmeules, Jules Alexandre; Cedraschi, Christine 2016
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Snapshot of the prescribing practice for the clopidogrel and esomeprazole coprescription and cost evaluation of the application guidelines Vernaz-Hegi, Nathalie; Rollason Gumprecht, Victoria; Adlere, Liene; Combescure, Christophe; ... Desmeules, Jules Alexandre 2016
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Severe Vincristine-Induced Neuropathic Pain in a CYP3A5 Nonexpressor With Reduced CYP3A4/5 Activity: Case Study Bosilkovska Weisskopf, Marija; Ing Lorenzini, Kuntheavy; Uppugunduri Satyanarayana, Chakradhara Rao; Desmeules, Jules Alexandre; ... Escher, Monica 2016
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Pharmacogenomics of Oral Antithrombotic Drugs Storelli, Flavia; Daali, Youssef; Desmeules, Jules Alexandre; Reny, Jean-Luc; Fontana, Pierre 2016
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Intestinal permeability and P-glycoprotein-mediated efflux transport of ticagrelor in Caco-2 monolayer cells Marsousi, Niloufar; Doffey-Lazeyras, Fabienne; Rudaz, Serge; Desmeules, Jules Alexandre; Daali, Youssef 2016
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The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesia Ralvenius, William T; Acuña, Mario A; Benke, Dietmar; Matthey, Alain; ... Besson, Marie 2016
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Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approach Marsousi, Niloufar; Samer, Caroline Flora; Fontana, Pierre; Reny, Jean-Luc; ... Daali, Youssef 2016
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Evaluation of Mutual Drug-Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method Bosilkovska Weisskopf, Marija; Samer, Caroline Flora; Deglon, Julien; Thomas, Aurélien; ... Daali, Youssef 2016
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Rivaroxaban-Induced Hemorrhage Associated with ABCB1 Genetic Defect Ing Lorenzini, Kuntheavy; Daali, Youssef; Fontana, Pierre; Desmeules, Jules Alexandre; Samer, Caroline Flora 2016
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Assessing the affective load in the narratives of women suffering from fibromyalgia: the clinicians' appraisal Cedraschi, Christine; Girard, Elodie Laure; Piguet, Valérie; Desmeules, Jules Alexandre; Allaz, Anne-Françoise 2015
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Providing Quality Therapeutics in Switzerland: Role of the Stakeholders and Recent Incentives for Further Improvements Besson, Marie; Samer, Caroline Flora; Rollason Gumprecht, Victoria; Dayer, Pierre; Desmeules, Jules Alexandre 2015
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A phase IIa randomized clinical study testing GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis associated endogenous retrovirus in multiple sclerosis patients - a twelve month follow-up Derfuss, Tobias; Curtin, François; Guebelin, Claudia; Bridel, Claire; ... Lalive d'Epinay, Patrice 2015
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Prescribing Generic Medication in Chronic Musculoskeletal Pain Patients: An Issue of Representations, Trust, and Experience in a Swiss Cohort Piguet, Valérie; D'Incau, Stéphanie; Besson, Marie; Desmeules, Jules Alexandre; Cedraschi, Christine 2015
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Prescription d’antidépresseurs dans le traitement de la douleur : rôle de la pharmacogénétique Rodieux, Frédérique; Piguet, Valérie; Berney, Patricia Elisabeth; Desmeules, Jules Alexandre; Besson, Marie 2015
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Cannabinoïdes médicaux dans les douleurs chroniques : aspects pharmacologiques Ing Lorenzini, Kuntheavy; Broers, Barbara; Lalive d'Epinay, Patrice; Dayer, Pierre; ... Piguet, Valérie 2015
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Is pholcodine a dangerous cough suppressant? Ing Lorenzini, Kuntheavy; Desmeules, Jules Alexandre; Piguet, Valérie 2015
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Use of metamizole in children and the risk of agranulocytosis: Is the benefit worth the risk? Rollason Gumprecht, Victoria; Desmeules, Jules Alexandre 2015
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A phase IIa randomised clinical study of GNbAC1, a humanised monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus in multiple sclerosis patients Derfuss, Tobias; Curtin, François; Guebelin, Claudia; Bridel, Claire; ... Lalive d'Epinay, Patrice 2015
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The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised double-blind, placebo-controlled phase 1/2 trial Csaki Huttner, Angela; Dayer, Julie-Anne; Yerly Ferrillo, Sabine; Combescure, Christophe; ... Siegrist, Claire-Anne 2015
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P-glycoprotein: a clue to vitamin K antagonist stabilization Gschwind, Liliane; Rollason Gumprecht, Victoria; Boehlen, Françoise; Rebsamen, Michela; ... Desmeules, Jules Alexandre 2015
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Drug-related problems identification in general internal medicine: The impact and role of the clinical pharmacist and pharmacologist Guignard, Bertrand; Bonnabry, Pascal; Perrier, Arnaud; Dayer, Pierre; ... Samer, Caroline Flora 2015
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GABAergic modulation in central sensitization in humans: a randomized placebo-controlled pharmacokinetic-pharmacodynamic study comparing clobazam with clonazepam in healthy volunteers Besson, Marie; Matthey, Alain; Daali, Youssef; Poncet, Antoine; ... Desmeules, Jules Alexandre 2015
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Evidence-Based Choice of P2Y12 Inhibitors in End Stage Renal Disease Patients: A Mini-Review Bouatou, Yassine; Samer, Caroline Flora; Fontana, Pierre; Daali, Youssef; Desmeules, Jules Alexandre 2015
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Markers of Individual Drug Metabolism: Towards the Development of a Personalized Antidepressant Prescription Lloret-Linares, Celia; Bellivier, Frank; Haffen, Emmanuel; Aubry, Jean-Michel; ... Besson, Marie 2015
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Impact of clinical decision support guidelines on therapeutic drug monitoring of gentamicin in newborns Fonzo-Christe, Caroline Cécile; Guignard, Bertrand; Zaugg, Claudia; Coehlo, Ana; ... Bonnabry, Pascal 2014
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Snapshot of Prescribing Practice for Clopidogrel and Esomeprazole Co-Prescription and Cost Evaluation of Guidelines Application Vernaz, Nathalie; Rollason Gumprecht, Victoria; Adlere, Liene; Bonnabry, Pascal; Desmeules, Jules Alexandre 2014
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Improving the primary care physicians' decision making for fibromyalgia in clinical practice: development and validation of the Fibromyalgia Detection (FibroDetect®) screening tool Baron, Ralf; Perrot, Serge; Guillemin, Isabelle; Alegre, Cayetano; ... Arnould, Benoit 2014
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