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Chronic fructose renders pancreatic beta-cells hyper-responsive to glucose-stimulated insulin secretion through extracellular ATP signaling Bartley, Clarissa; Brun, Thierry; Oberhauser, Lucie; Grimaldi, Mariagrazia; ... Maechler, Pierre 2019
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Successful pregnancy and delivery after simultaneous islet-kidney transplantation Assalino, Michela; Podetta, Michèle; Mischler, Sandrine; Francini, Katyuska; ... Berney, Thierry 2018
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Islet transplantation versus insulin therapy in patients with type 1 diabetes with severe hypoglycaemia or poorly controlled glycaemia after kidney transplantation (TRIMECO): a multicentre, randomised controlled trial Lablanche, Sandrine; Vantyghem, Marie-Christine; Kessler, Laurence; Wojtusciszyn, Anne; ... Benhamou, Pierre-Yves 2018
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NLRP3 inflammasome is expressed and regulated in human islets Lebreton, Fanny; Berishvili Berney, Ekaterine; Parnaud, Géraldine; Rouget, Caroline; ... Lavallard, Vanessa 2018
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A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-Cells Buenaventura, Teresa; Kanda, Nisha; Douzenis, Phoebe C; Jones, Ben; ... Tomas Catala, Alejandra Del Don 2018
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Pancreas preservation fluid microbial contamination is associated with poor islet isolation outcomes - a multi centre cohort study Meier, Raphaël; Andrey, Diego Olivier; Sun, Pamela; Niclauss, Nadja; ... Berney, Thierry 2018
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LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus Cobo-Vuilleumier, Nadia; Lorenzo, Petra I; Rodríguez, Noelia García; Herrera Gómez, Irene de Gracia; ... Gauthier, Benoit R 2018
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Pancreatic α- and β-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression Petrenko, Volodymyr; Saini, Camille; Morele Giovannoni, Laurianne; Gobet, Cedric; ... Dibner, Charna 2017
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Cell rearrangement in transplanted human islets Lavallard, Vanessa; Armanet, Mathieu; Parnaud, Géraldine; Meyer, Jérémy; ... Bosco, Domenico 2016
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Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose Johnston, Natalie R; Mitchell, Ryan K; Haythorne, Elizabeth; Pessoa, Maria Paiva; ... Hodson, David J 2016
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Sorcin Links Pancreatic β-Cell Lipotoxicity to ER Ca2+ Stores Marmugi, Alice; Parnis, Julia; Chen, Xi; Carmichael, LeAnne; ... Leclerc, Isabelle 2016
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Asymmetrical distribution of δ and PP cells in human pancreatic islets Barbieux, Charlotte; Parnaud, Géraldine; Lavallard, Vanessa; Brioudes, Estelle; ... Bosco, Domenico 2016
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Activation of nicotinic acetylcholine receptors decreases apoptosis in human and female murine pancreatic islets Klee, Philippe; Bosco, Domenico; Guerardel, Audrey; Somm, Emmanuel; ... Schwitzgebel Luscher, Valérie 2016
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Cadherin Engagement Improves Insulin Secretion of Single Human β-Cells Parnaud, Géraldine; Lavallard, Vanessa; Bedat, Benoît; Matthey-Doret, David; ... Bosco, Domenico 2015
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Human islet distribution programme for basic research: activity over the last 5 years Nano, Rita; Bosco, Domenico; Kerr-Conte, Julie A; Karlsson, Marie; ... Piemonti, Lorenzo 2015
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Inflammatory Chemokines MIP-1δ and MIP-3α Are Involved in the Migration of Multipotent Mesenchymal Stromal Cells Induced by Hepatoma Cells Lejmi, Esma; Perriraz-Mayer, Nadja; Clement, Sophie; Morel, Philippe; ... Gonelle-Gispert, Carmen 2015
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Slow potentials encode intercellular coupling and insulin demand in pancreatic beta cells Lebreton, Fanny; Pirog, Antoine; Belouah, Isma; Bosco, Domenico; ... Lang, Jochen 2015
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Diabetogenic milieus induce specific changes in mitochondrial transcriptome and differentiation of human pancreatic islets Brun, Thierry; Li, Ning; Jourdain, Alexis; Gaudet, Pascale; ... Maechler, Pierre 2015
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Five-Year Metabolic, Functional, and Safety Results of Patients With Type 1 Diabetes Transplanted With Allogenic Islets Within the Swiss-French GRAGIL Network Lablanche, Sandrine; Borot, Sophie; Wojtusciszyn, Anne; Bayle, Francois; ... Benhamou, Pierre-Yves 2015
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Enhancement of islet engraftment and achievement of long-term islet allograft survival by Toll-like receptor 4 blockade Giovannoni, Laurianne; Muller, Yannick; Lacotte, Stéphanie; Parnaud, Géraldine; ... Berney, Thierry 2015
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The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes Belgardt, Bengt-Frederik; Ahmed, Kashan; Spranger, Martina; Latreille, Mathieu; ... Stoffel, Markus 2015
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Proteasome dysfunction mediates high glucose-induced apoptosis in rodent beta cells and human islets Broca, Christophe; Varin, Elodie; Armanet, Mathieu Pierre Jean; Tourrel-Cuzin, Cécile; ... Wojtusciszyn, Anne 2014
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Incretin-modulated beta cell energetics in intact islets of Langerhans Hodson, David J; Tarasov, Andrei I; Gimeno Brias, Silvia; Mitchell, Ryan K; ... Rutter, Guy A 2014
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Hypoxia lowers SLC30A8/ZnT8 expression and free cytosolic Zn(2+) in pancreatic beta cells Gerber, Philipp A; Bellomo, Elisa A; Hodson, David J; Meur, Gargi; ... Rutter, Guy A 2014
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Islet of Langerhans isolation from pediatric and juvenile donor pancreases Meier, Raphaël; Sert, Ismail; Morel, Philippe; Muller, Yannick; ... Berney, Thierry 2014
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ADCY5 Couples Glucose to Insulin Secretion in Human Islets Hodson, David J; Mitchell, Ryan K; Marselli, Lorella; Pullen, Timothy J; ... Rutter, Guy A 2014
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Impact of anti-insulin antibodies on islet transplantation outcome: data from the GRAGIL Network Lablanche, Sandrine; Borot, Sophie; Thaunat, Olivier; Bayle, Francois; ... Benhamou, Pierre Y 2014
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Calcineurin inhibitor-free immunosuppressive regimen in type 1 diabetes patients receiving islet transplantation: single-group phase 1/2 trial Maffi, Paola; Berney, Thierry; Nano, Rita; Niclauss, Nadja; ... Piemonti, Lorenzo 2014
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Survival of free and encapsulated human and rat islet xenografts transplanted into the mouse bone marrow Meier, Raphaël; Seebach, Jorg Dieter; Morel, Philippe; Mahou, Redouan; ... Muller, Yannick 2014
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Lipotoxicity disrupts incretin-regulated human β cell connectivity Hodson, David J; Mitchell, Ryan K; Bellomo, Elisa A; Sun, Gao; ... Rutter, Guy A 2013
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Cell-type, allelic and genetic signatures in the human pancreatic beta cell transcriptome Nica, Alexandra; Ongen, Halit; Irminger, Jean-Claude; Bosco, Domenico; ... Dermitzakis, Emmanouil 2013
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Losartan, an angiotensin II type 1 receptor blocker, protects human islets from glucotoxicity through the phospholipase C pathway Madec, Anne-Marie; Cassel, Roméo; Dubois, Séverine; Ducreux, Sylvie; ... Thivolet, Charles 2013
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Quantification of islet loss and graft functionality during immune rejection by 3-tesla MRI in a rat model Borot, Sophie; Crowe, Lindsey A; Parnaud, Géraldine; Ris, Frédéric; ... Berney, Thierry 2013
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Endocrine secretory reserve and proinsulin processing in recipients of islet of langerhans versus whole pancreas transplants Elkhafif, Nabeel; Borot, Sophie; Morel, Philippe; Demuylder-Mischler, Sandrine; ... Berney, Thierry 2013
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Transplanted human pancreatic islets after long-term insulin independence Muller, Y D; Gupta, Sajal; Morel, Philippe; Borot, Sophie; ... Berney, Thierry 2013
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Autonomous and self-sustained circadian oscillators displayed in human islet cells Pulimeno, Pamela; Mannic, Tiphaine; Sage, D; Giovannoni, Laurianne; ... Dibner, Charna 2013
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Pancreatic magnetic resonance imaging after manganese injection distinguishes type 2 diabetic and normoglycemic patients Botsikas, Diomidis; Terraz, Sylvain; Vinet, Laurent; Lamprianou, Smaragda; ... Montet, Xavier Cédric Rodolphe 2012
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Comparative impact on islet isolation and transplant outcome of the preservation solutions Institut Georges Lopez-1, University of Wisconsin, and Celsior Niclauss, Nadja; Wojtusciszyn, Anne; Morel, Philippe; Demuylder-Mischler, Sandrine; ... Berney, Thierry 2012
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A novel method for quantitative monitoring of transplanted islets of langerhans by positive contrast magnetic resonance imaging Crowe, L A; Ris, Frédéric; Nielles-Vallespin, S; Speier, P; ... Vallée, Jean-Paul 2011
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Taspoglutide, a novel human once-weekly GLP-1 analogue, protects pancreatic β-cells in vitro and preserves islet structure and function in the Zucker diabetic fatty rat in vivo Uhles, S; Wang, Haiyan; Bénardeau, A; Prummer, M; ... Sebokova, E 2011
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Islet autotransplantation after extended pancreatectomy for focal benign disease of the pancreas Ris, Frédéric; Niclauss, Nadja; Morel, Philippe; Demuylder-Mischler, Sandrine; ... Berney, Thierry 2011
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Connexins: key mediators of endocrine function Bosco, Domenico; Haefliger, Jacques-Antoine; Meda, Paolo 2011
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Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass Esterházy, Daria; Stützer, Ina; Wang, Haiyan; Rechsteiner, Markus P; ... Stoffel, Markus 2011
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The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {beta}-cells against stress-induced apoptosis Baquie, Mathurin; St-Onge, Luc; Kerr-Conte, Julie; Cobo-Vuilleumier, Nadia; ... Gauthier, Benoît 2011
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Rapamycin impairs proliferation of transplanted islet β cells Niclauss, Nadja; Bosco, Domenico; Morel, Philippe; Giovannoni, Laurianne; ... Parnaud, Géraldine 2011
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Influence of donor age on islet isolation and transplantation outcome Niclauss, Nadja; Bosco, Domenico; Morel, Philippe; Demuylder-Mischler, Sandrine; ... Berney, Thierry 2011
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Impact of the number of infusions on 2-year results of islet-after-kidney transplantation in the GRAGIL network Borot, Sophie; Niclauss, Nadja; Wojtusciszyn, Anne; Brault, Coralie; ... Berney, Thierry 2011
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Cadherin engagement protects human β-cells from apoptosis Parnaud, Géraldine; Gonelle-Gispert, Carmen; Morel, Philippe; Giovannoni, Laurianne; ... Bosco, Domenico 2011
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Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism Vetterli, Laurene Marine; Brun, Thierry; Giovannoni, Laurianne; Bosco, Domenico; Maechler, Pierre 2011
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Combined pancreatic islet-lung transplantation: a novel approach to the treatment of end-stage cystic fibrosis Kessler, L.; Bakopoulou, S.; Kessler, R.; Massard, G.; ... Berney, Thierry 2010
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