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 TitleAuthors / EditorsDate
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Electronic and Conformational Effects on the Lipophilicity of Isomers and Analogs of the Neurotoxin 1-Methyl-4-Phenylpyridinium (Mpp+) Altomare, Cosimo; Carrupt, Pierre-Alain; el Tayar, Nabil; Testa, Bernard; Nagatsu, T. 1991
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The hydrogen-bonding of drugs : Its experimental-determination and role in pharmacokinetics and pharmacodynamics Testa, Bernard; el Tayar, Nabil; Altomare, Cosimo; Carrupt, Pierre-Alain; ... Carotti, Angelo 1992
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Quantitative structure-metabolism relationship analyses of MAO-mediated toxication of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and analogues Altomare, Cosimo; Carrupt, Pierre-Alain; Gaillard, Patrick; el Tayar, Nabil; ... Carotti, Angelo 1992
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Lipophilicity and hydrogen-bonding capacity : their role in drug-binding and disposition Testa, Bernard; el Tayar, Nabil; Altomare, Cosimo; Carrupt, Pierre-Alain; Tsai, Ruey-Shiuan 1993
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Enantiomeric resolution of sulfoxides on a Dach-Dnb chiral stationary-phase : a quantitative structure-enantioselective retention relationship (Qserr) study Altomare, Cosimo; Carotti, Angelo; Cellamare, S.; Fanelli, F.; ... Testa, Bernard 1993
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Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) McNaught, K. S.; Thull, Ulrike; Carrupt, Pierre-Alain; Altomare, Cosimo; ... Marsden, C. D. 1995
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Inhibition of monoamine oxidase by isoquinoline derivatives. Qualitative and 3D-quantitative structure-activity relationships Thull, Ulrike; Kneubuhler, S.; Gaillard, Patrick; Carrupt, Pierre-Alain; ... McNaught, K. S. 1995
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Inhibition of alpha-ketoglutarate dehydrogenase by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) McNaught, K. S.; Altomare, Cosimo; Cellamare, S.; Carotti, Angelo; ... Marsden, C. D. 1995
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X-ray crystal structure, partitioning behavior, and molecular modeling study of piracetam-type nootropics: insights into the pharmacophore Altomare, Cosimo; Cellamare, S.; Carotti, Angelo; Casini, G.; ... Testa, Bernard 1995
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Inhibition of monoamine oxidase-B by 5H-indeno[1,2-c]pyridazines: biological activities, quantitative structure-activity relationships (QSARs) and 3D-QSARs Kneubuhler, S.; Thull, Ulrike; Altomare, Cosimo; Carta, V.; ... Testa, Bernard 1995
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Effects of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mitochondrial respiration McNaught, K. S.; Thull, Ulrike; Carrupt, Pierre-Alain; Altomare, Cosimo; ... Marsden, C. D. 1996
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Inhibition of [3H]dopamine uptake into striatal synaptosomes by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine McNaught, K. S.; Thull, Ulrike; Carrupt, Pierre-Alain; Altomare, Cosimo; ... Marsden, C. D. 1996
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Nigral cell loss produced by infusion of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine McNaught, K. S.; Thull, Ulrike; Carrupt, Pierre-Alain; Altomare, Cosimo; ... Marsden, C. D. 1996
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Toxicity to PC12 cells of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine McNaught, K. S.; Thull, Ulrike; Carrupt, Pierre-Alain; Altomare, Cosimo; ... Marsden, C. D. 1996
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Isoquinoline derivatives as endogenous neurotoxins in the aetiology of Parkinson's disease McNaught, K. S.; Carrupt, Pierre-Alain; Altomare, Cosimo; Cellamare, S.; ... Marsden, C. D. 1998
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Inhibition of monoamine oxidase-B by condensed pyridazines and pyrimidines: Effects of lipophilicity and structure-activity relationships Altomare, Cosimo; Cellamare, S.; Summo, L.; Catto, M.; ... Stoeckli-Evans, H. 1998
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Reversible inhibition of MAO-A and B by diazoheterocyclic compounds: Development of QSAR/CoMFA models Altomare, Cosimo; Carieri, A.; Cellamare, S.; Summo, L.; ... Testa, Bernard 2000
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Inhibition of monoamine oxidases by functionalized coumarin derivatives: biological activities, QSARs, and 3D-QSARs Gnerre, Carmela; Catto, M.; Leonetti, F.; Weber, P.; ... Testa, Bernard 2000
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Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase Bruhlmann, C.; Ooms, F.; Carrupt, Pierre-Alain; Testa, Bernard; ... Carotti, Angelo 2001