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Bioactivation of the narcotic drug codeine in human liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation (cytochrome P-450 dbl/bufI) Dayer, Pierre; Desmeules, Jules Alexandre; Leemann, Thierry; Striberni, Rita 1988
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Impact of environmental and genetic factors on codeine analgesia Desmeules, Jules Alexandre; Gascon, Marie-Paule; Dayer, P; Magistris, M 1991
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In vitro forecasting of drugs that may interfere with codeine bioactivation Dayer, Pierre; Desmeules, Jules Alexandre; Striberni, Rita 1992
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Opposite effects of axon damage on heat shock proteins (hsp 70) and ubiquitin contents in motor neurons of neuropathic rats Lantéri-Minet, M; Desmeules, Jules Alexandre; Menetrey, Danila 1993
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The highly selective delta agonist BUBU induces an analgesic effect in normal and arthritic rat and this action is not affected by repeated administration of low doses of morphine Desmeules, Jules Alexandre; Kayser, V; Gacel, G; Guilbaud, Georges Silvain; Roques, B P 1993
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Selective opioid receptor agonists modulate mechanical allodynia in an animal model of neuropathic pain Desmeules, Jules Alexandre; Kayser, V; Guilbaud, Georges Silvain 1993
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The pharmacology of tramadol Dayer, P; Collart Leemann, Laurence; Desmeules, Jules Alexandre 1994
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Differential action of morphine and various opioid agonists on thermal allodynia and hyperalgesia in mononeuropathic rats Lee, S; Kayser, v; Desmeules, Jules Alexandre; Guilbaud, Georges Silvain 1994
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Pericardite recidivante induite par la mesalazine (5-ASA) Desmeules, Jules Alexandre; Vogt-Ferrier, Nicole Barbara; Loizeau, Sylviane; Angelillo-Scherrer, A; Dayer, P 1994
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Evaluation de la douleur chronique des patients d'age geriatrique Desmeules, Jules Alexandre; Allaz, Anne-Françoise; Binyet, S; Piguet, Valérie; ... Dayer, P 1994
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Arret de travail et comportement-maladie chez des patients souffrant de douleurs chroniques Allaz, Anne-Françoise; Binyet, S; Desmeules, Jules Alexandre; Piguet, Valérie; Dayer, P 1994
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Time-course of nociceptive disorders induced by chronic loose ligatures of the rat sciatic nerve and changes of the acetylcholinesterase transport along the ligated nerve Filliatreau, G; Attal, N; Hässig, R; Guilbaud, Georges Silvain; ... DiGiamberardino, L 1994
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Quelle posologie antalgique du paracetamol? Piguet, Valérie; Desmeules, Jules Alexandre; Collart Leemann, Laurence; Dayer, P 1994
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Facteurs predictifs d'une resistance au traitement des douleurs neuropathiques Desmeules, Jules Alexandre; Constantin, C; Allaz, Anne-Françoise; Piguet, Valérie; ... Dayer, P 1994
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Influence of the sympathetic nervous system in the development of abnormal pain-related behaviours in a rat model of neuropathic pain Desmeules, Jules Alexandre; Kayser, V; Weil-Fuggaza, J; Bertrand, A; Guilbaud, Georges Silvain 1995
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Systemic clonidine differentially modulates the abnormal reactions to mechanical and thermal stimuli in rats with peripheral mononeuropathy Kayser, V; Desmeules, Jules Alexandre; Guilbaud, Georges Silvain 1995
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Stereoselective interaction between piroxicam and acenocoumarol Bonnabry, Pascal; Desmeules, Jules Alexandre; Rudaz, Serge; Leemann, T.; ... Dayer, Pierre 1996
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Contribution of monoaminergic modulation to the analgesic effect of tramadol Desmeules, Jules Alexandre; Piguet, Valérie; Collart Leemann, Laurence; Dayer, Pierre 1996
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Atteintes hepatiques medicamenteuses, il faut y penser ! Oestreicher, M; Desmeules, Jules Alexandre; Giostra, Emiliano; Gross, B; ... Dayer, P 1996
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Pharmacologie du tramadol Dayer, Pierre; Desmeules, Jules Alexandre; Collart Leemann, Laurence 1997
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