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NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice Zhang, Hongbo; Ryu, Dongryeol; Wu, Yibo; Gariani, Karim; ... Auwerx, Johan 2016
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Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice Gariani, Karim; Menzies, Keir J; Ryu, Dongryeol; Wegner, Casey J; ... Auwerx, Johan 2016
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NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation Ryu, Dongryeol; Zhang, Hongbo; Ropelle, Eduardo R; Sorrentino, Vincenzo; ... Auwerx, Johan 2016
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Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease Gariani, Karim; Ryu, Dongryeol; Menzies, Keir J; Yi, Hyon-Seung; ... Auwerx, Johan 2017
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An integrated systems genetics and omics toolkit to probe gene function Li, Hao; Wang, Xu; Rukina, Daria; Huang, Qingyao; ... Auwerx, Johan 2018
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Genetic regulation of plasma lipid species and their association with metabolic phenotypes Jha, Pooja; McDevitt, Molly T; Halilbasic, Emina; Williams, Evan G; ... Auwerx, Johan 2018
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Systems Analyses Reveal Physiological Roles and Genetic Regulators of Liver Lipid Species Jha, Pooja; McDevitt, Molly T; Gupta, Rahul; Quiros, Pedro M; ... Pagliarini, David J 2018
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De novo NAD+ synthesis enhances mitochondrial function and improves health Katsyuba, Elena; Mottis, Adrienne; Zietak, Marika; De Franco, Francesca; ... Auwerx, Johan 2018
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Nicotinamide pathway-dependent Sirt1 activation restores calcium homeostasis to achieve neuroprotection in spinocerebellar ataxia type 7 Stoyas, Colleen A; Bushart, David D; Switonski, Pawel M; Ward, Jacqueline M; ... La Spada, Albert R 2020
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Differential role of nicotinamide adenine dinucleotide deficiency in acute and chronic kidney disease Faivre, Anna; Katsyuba, Elena; Verissimo, Thomas; Lindenmeyer, Maja; ... De Seigneux Matthey, Sophie 2021