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Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety Samer, Caroline Flora; Daali, Youssef; Wagner, M.; Hopfgartner, Gerard; ... Desmeules, Jules Alexandre 2010
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The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone Samer, Caroline Flora; Daali, Youssef; Wagner, M.; Hopfgartner, Gerard; ... Desmeules, Jules Alexandre 2010
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Ritonavir inhibits the two main prasugrel bioactivation pathways in vitro: a potential drug-drug interaction in HIV patients Daali, Youssef; Ancrenaz, Virginie; Bosilkovska Weisskopf, Marija; Dayer, Pierre; Desmeules, Jules Alexandre 2011
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How organic anions accumulate in hepatocytes lacking Mrp2: evidence in rat liver Millet, Philippe; Moulin, Marcelle; Stieger, Bruno; Daali, Youssef; Pastor, Catherine 2011
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HZ166, a novel GABAA receptor subtype-selective benzodiazepine site ligand, is antihyperalgesic in mouse models of inflammatory and neuropathic pain Di Lio, Alessandra; Benke, Dietmar; Besson, Marie; Desmeules, Jules Alexandre; ... Zeilhofer, Hanns Ulrich 2011
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A randomized, controlled trial validates a peripheral supra-additive antihyperalgesic effect of a paracetamol-ketorolac combination Ing Lorenzini, Kuntheavy; Besson, Marie; Daali, Youssef; Salomon, Denis; ... Desmeules, Jules Alexandre 2011
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Automated system for on-line desorption of dried blood spots applied to LC/MS/MS pharmacokinetic study of flurbiprofen and its metabolite Deglon, Julien; Thomas, Aurélien; Daali, Youssef; Lauer, Estelle; ... Staub, Christian 2011
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Validation of the simplified UVB model to assess the pharmacodynamics of analgesics in healthy human volunteers Ing Lorenzini, Kuntheavy; Besson, Marie; Daali, Youssef; Salomon, Denis; ... Desmeules, Jules Alexandre 2012
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Analgesics in patients with hepatic impairment: pharmacology and clinical implications Bosilkovska Weisskopf, Marija; Walder, Bernhard; Besson, Marie; Daali, Youssef; Desmeules, Jules Alexandre 2012
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Transcriptional regulation of CYP2C19 and its role in altered enzyme activity Uppugunduri Satyanarayana, Chakradhara Rao; Daali, Youssef; Desmeules, Jules Alexandre; Dayer, Pierre; ... Ansari Djaberi, Marc Georges 2012
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NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion Li, Ning; Li, Bin; Brun, Thierry; Deffert-Delbouille, Christine; ... Maechler, Pierre 2012
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Influence of the paraoxonase-1 Q192R genetic variant on clopidogrel responsiveness and recurrent cardiovascular events: a systematic review and meta-analysis Reny, Jean-Luc; Combescure, Christophe; Daali, Youssef; Fontana, Pierre 2012
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The paraoxonase-1 pathway is not a major bioactivation pathway of clopidogrel in vitro Ancrenaz, Virginie; Desmeules, Jules Alexandre; James, Richard William; Fontana, Pierre; ... Daali, Youssef 2012
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A simplified method for busulfan monitoring using dried blood spot in combination with liquid chromatography/tandem mass spectrometry Ansari Djaberi, Marc Georges; Uppugunduri Satyanarayana, Chakradhara Rao; Deglon, Julien; Théorêt, Yves; ... Daali, Youssef 2012
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Pharmacokinetic-pharmacodynamic modelling of opioids in healthy human volunteers. A minireview Ing Lorenzini, Kuntheavy; Daali, Youssef; Dayer, Pierre; Desmeules, Jules Alexandre 2012
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Liver kidney microsomal type 1 antibodies reduce the CYP2D6 activity in patients with chronic hepatitis C virus infection Girardin, François; Daali, Youssef; Gex-Fabry, Marianne; Rebsamen, Michela; ... Desmeules, Jules Alexandre 2012
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Oral flurbiprofen metabolic ratio assessment using a single-point dried blood spot Daali, Youssef; Samer, Caroline Flora; Deglon, Julien; Thomas, Aurélien; ... Desmeules, Jules Alexandre 2012
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Serotonin syndrome following drug-drug interactions and CYP2D6 and CYP2C19 genetic polymorphisms in an HIV-infected patient Lorenzini, Kuntheavy I.; Calmy, Alexandra; Ambrosioni Czyrko, Juan; Assouline, Benjamin; ... Samer, Caroline Flora 2012
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Influence of CYP2D6 activity on pre-emptive analgesia by the N-methyl-D-aspartate antagonist dextromethorphan in a randomized controlled trial of acute pain Ehret, Georg Benedikt; Daali, Youssef; Chabert, Jocelyne; Rebsamen, Michela; ... Desmeules, Jules Alexandre 2013
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Antihyperalgesic Effect of the GABA(A) Ligand Clobazam in a Neuropathic Pain Model in Mice: A Pharmacokinetic-Pharmacodynamic Study Besson, Marie; Daali, Youssef; Di Lio, Alessandra; Dayer, Pierre; ... Desmeules, Jules Alexandre 2013
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