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Toxication of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and analogs by monoamine oxidase. A structure-reactivity relationship study Maret, G.; el Tayar, Nabil; Carrupt, Pierre-Alain; Testa, Bernard; ... Baird, M. 1990
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The MPTP story: MAO activates tetrahydropyridine derivatives to toxins causing parkinsonism Maret, G.; Testa, Bernard; Jenner, P.; el Tayar, Nabil; Carrupt, Pierre-Alain 1990
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Molecular electrostatic potentials for characterizing drug-biosystem interactions Carrupt, Pierre-Alain; el Tayar, Nabil; Karlen, A.; Testa, Bernard 1991
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Ionization behavior and ionization-dependent conformation of raclopride, a dopamine-D2 receptor antagonist Carrupt, Pierre-Alain; Tsai, Ruey-Shiuan; el Tayar, Nabil; Testa, Bernard; ... Hogberg, Thomas 1991
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Percutaneous penetration of drugs: a quantitative structure-permeability relationship study el Tayar, Nabil; Tsai, Ruey-Shiuan; Testa, Bernard; Carrupt, Pierre-Alain; ... Leo, A. 1991
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Partitioning of solutes in different solvent systems: the contribution of hydrogen-bonding capacity and polarity el Tayar, Nabil; Tsai, Ruey-Shiuan; Testa, Bernard; Carrupt, Pierre-Alain; Leo, A. 1991
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Structure lipophilicity relationships of zwitterionic amino-acids Tsai, Ruey-Shiuan; Testa, Bernard; el Tayar, Nabil; Carrupt, Pierre-Alain 1991
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Morphine 6-Glucuronide and Morphine 3-Glucuronide As Molecular Chameleons with Unexpected Lipophilicity Carrupt, Pierre-Alain; Testa, Bernard; Bechalany, A.; el Tayar, Nabil; ... Perrissoud, D. 1991
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Electronic and Conformational Effects on the Lipophilicity of Isomers and Analogs of the Neurotoxin 1-Methyl-4-Phenylpyridinium (Mpp+) Altomare, Cosimo; Carrupt, Pierre-Alain; el Tayar, Nabil; Testa, Bernard; Nagatsu, T. 1991
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Quantitative structure-affinity relationships of dopamine D2 receptor antagonists - a comparison between orthopramides and 6-methoxysalicylamides de Paulis, Tomas; el Tayar, Nabil; Carrupt, Pierre-Alain; Testa, Bernard; Van de Waterbeemd, Hans 1991
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Octan-1-Ol-water partition-coefficients of zwitterionic alpha-amino-acids - determination by centrifugal partition chromatography and factorization into steric hydrophobic and polar components el Tayar, Nabil; Tsai, Ruey-Shiuan; Carrupt, Pierre-Alain; Testa, Bernard 1992
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The hydrogen-bonding of drugs : Its experimental-determination and role in pharmacokinetics and pharmacodynamics Testa, Bernard; el Tayar, Nabil; Altomare, Cosimo; Carrupt, Pierre-Alain; ... Carotti, Angelo 1992
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Physicochemical properties and transport behavior of piribedil : considerations on its membrane-crossing potential Tsai, Ruey-Shiuan; el Tayar, Nabil; Carrupt, Pierre-Alain; Testa, Bernard 1992
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Solvatochromic analysis of the retention mechanism of 2 novel stationary phases used for measuring lipophilicity by Rp-Hplc Vallat, P.; Fan, W. Z.; el Tayar, Nabil; Carrupt, Pierre-Alain; Testa, Bernard 1992
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Quantitative structure-metabolism relationship analyses of MAO-mediated toxication of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and analogues Altomare, Cosimo; Carrupt, Pierre-Alain; Gaillard, Patrick; el Tayar, Nabil; ... Carotti, Angelo 1992
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Polar intermolecular interactions encoded in partition-coefficients :an indirect estimation of hydrogen-bond parameters of polyfunctional solutes el Tayar, Nabil; Testa, Bernard; Carrupt, Pierre-Alain 1992
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Chirality in drug research - stereomania, stereophobia, or stereophilia Testa, Bernard; Carrupt, Pierre-Alain; Christiansen, L. H.; Christoffersen, P.; Reist, Marianne 1993
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Lipophilicity and hydrogen-bonding capacity : their role in drug-binding and disposition Testa, Bernard; el Tayar, Nabil; Altomare, Cosimo; Carrupt, Pierre-Alain; Tsai, Ruey-Shiuan 1993
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Physicochemical and structural-properties of nonsteroidal antiinflammatory oxicams Tsai, Ruey-Shiuan; Carrupt, Pierre-Alain; el Tayar, Nabil; Giroud, Y.; ... Tillement, J. P. 1993
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Measurement of partition-coefficients using centrifugal partition chromatography : method development and application to the determination of solute structural-properties Tsai, Ruey-Shiuan; Carrupt, Pierre-Alain; Testa, Bernard 1993
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