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A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets Marchetti, P; Lupi, R; Bugliani, Marco; Kirkpatrick, Clare; ... Dotta, F 2012
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A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling Knight, Zachary A; Gonzalez, Beatriz; Feldman, Morri E; Zunder, Eli R; ... Shokat, Kevan M 2006
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A role for cytosolic isocitrate dehydrogenase as a negative regulator of glucose signaling for insulin secretion in pancreatic ß-cells Guay, Claudiane; Joly, Erik; Pepin, Emilie; Barbeau, Annie; ... Prentki, Marc 2013
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A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-Cells Buenaventura, Teresa; Kanda, Nisha; Douzenis, Phoebe C; Jones, Ben; ... Tomas Catala, Alejandra Del Don 2018
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Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2 Feldman, Morris E; Apsel, Beth; Lempiainen, Aino; Loewith, Robbie Joséph; ... Shokat, Kevan M 2009
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Adenovirus-mediated silencing of synaptotagmin 9 inhibits Ca2+-dependent insulin secretion in islets Iezzi-Bakhtiari, Mariella; Eliasson, Lena; Fukuda, Mitsunori; Wollheim, Claes 2005
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Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation Phelps, Edward A; Cianciaruso, Chiara; Santo-Domingo, Jaime; Pasquier, Miriella; ... Baekkeskov, Steinunn 2017
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AEB-071 has minimal impact on onset of autoimmune diabetes in NOD mice Merani, S.; Edgar, R. L.; Toso, Christian; Emamaullee, J.; ... Shapiro, A M. J. 2009
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Alpha cell-specific Men1 ablation triggers the transdifferentiation of glucagon-expressing cells and insulinoma development Lu, Jieli; Herrera, Pedro Luis; Carreira, Christine; Bonnavion, Remy; ... Zhang, C. X. 2010
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An arginine to cysteine(252) mutation in insulin receptors from a patient with severe insulin resistance inhibits receptor internalisation but preserves signalling events Hamer, Isabelle; Foti, Michelangelo; Emkey, R; Cordier-Bussat, M; ... Carpentier, J-L 2002
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Beta-cell-targeted expression of a dominant-negative hepatocyte nuclear factor-1 alpha induces a maturity-onset diabetes of the young (MODY)3-like phenotype in transgenic mice Hagenfeldt-Johansson, K. A.; Herrera, Pedro Luis; Wang, Haiyan; Gjinovci, A.; ... Wollheim, Claes 2001
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Biochemical quantification of total brain glycogen concentration in rats under different glycemic states Morgenthaler, Florence; Koski, Dee M; Kraftsik, Rudolf; Henry, Pierre-Gilles; Gruetter, Rolf 2006
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Calcium-induced insulin release in monolayer culture of the endocrine pancreas. Studies with ionophore A23187 Wollheim, Claes; Blondel, B; Trueheart, P A; Renold, A E; Sharp, G W 1975
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Chronic mTOR inhibition by rapamycin induces muscle insulin resistance despite weight loss in rats Deblon, Nicolas; Bourgoin, Lucie; Veyrat-Durebex, Christelle; Peyrou, Marion; ... Foti, Michelangelo 2012
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Connexin implication in the control of the murine beta-cell mass Klee, Philippe; Lamprianou, Smaragda; Charollais, Anne; Caille, Dorothée; ... Meda, Paolo 2011
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Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice Cantley, James; Selman, Colin; Shukla, Deepa; Abramov, A. Y.; ... Withers, D. J. 2009
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Differential rates of conversion of rat proinsulins I and II. Evidence for slow cleavage at the B-chain/C-peptide junction of proinsulin II Sizonenko, S. V.; Halban, Philippe A. 1991
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Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice Berglund, Eric D; Vianna, Claudia R; Donato, Jose (Jr); Kim, Mi Hwa; ... Elmquist, Joel K 2012
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Evidence against a direct role of klotho in insulin resistance Lorenzi, Olivier; Veyrat-Durebex, Christelle; Wollheim, Claes; Villemin, Pascal; ... Vischer, Ulrich Max 2010
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Expression and localisation of synaptotagmin isoforms in endocrine beta-cells: their function in insulin exocytosis Gut, A; Kiraly-Borri, Catherine Eva; Fukuda, M; Mikoshiba, K; ... Lang, Jochen 2001
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