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A clathrin-coated, Golgi-related compartment of the insulin secreting cell accumulates proinsulin in the presence of monensin Orci, Lelio; Halban, Philippe A.; Amherdt, M.; Ravazzola, M.; ... Perrelet, A. 1984
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Differential rates of conversion of rat proinsulins I and II. Evidence for slow cleavage at the B-chain/C-peptide junction of proinsulin II Sizonenko, S. V.; Halban, Philippe A. 1991
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Inhibition of proinsulin to insulin conversion in rat islets using arginine and lysine analogs. Lack of effect on rate of release of modified products Halban, Philippe A. 1982
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Insulin, not C-peptide (proinsulin), is present in crinophagic bodies of the pancreatic B-cell Orci, Lelio; Ravazzola, M.; Amherdt, M.; Yanaihara, C.; ... Perrelet, Alain 1984
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Kinetics of proinsulin conversion in human islets Sizonenko, Stéphane; Irminger, J. C.; Buehler, Leo Hans; Deng, Shaoping; ... Halban, Philippe A. 1993
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Nonconverted, amino acid analog-modified proinsulin stays in a Golgi-derived clathrin-coated membrane compartment Orci, Lelio; Halban, Philippe A.; Amherdt, M.; Ravazzola, M.; ... Perrelet, Alain 1984
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pH-independent and -dependent cleavage of proinsulin in the same secretory vesicle Orci, Lelio; Halban, Philippe A.; Perrelet, Alain; Amherdt, M.; ... Anderson, R. G. 1994
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Processing of proinsulin by furin, PC2, and PC3 in (co) transfected COS (monkey kidney) cells Vollenweider, F.; Kaufmann, J.; Irminger, J. C.; Halban, Philippe A. 1995
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Processing of proinsulin by transfected hepatoma (FAO) cells Vollenweider, F.; Irminger, Jean-Claude; Gross, D. J.; Villa-Komaroff, L.; Halban, Philippe A. 1992
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Proinsulin modified by analogues of arginine and lysine is degraded rapidly in pancreatic B-cells Halban, Philippe A.; Amherdt, M.; Orci, Lelio; Renold, A. E. 1984
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Proinsulin processing in the rat insulinoma cell line INS after overexpression of the endoproteases PC2 or PC3 by recombinant adenovirus Irminger, Jean-Claude; Meyer, K.; Halban, Philippe A. 1996
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Proinsulin processing in the regulated and the constitutive secretory pathway Halban, Philippe A. 1994
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Proteolytic maturation of insulin is a post-Golgi event which occurs in acidifying clathrin-coated secretory vesicles Orci, Lelio; Ravazzola, M.; Storch, M. J.; Anderson, R. G.; ... Perrelet, A. 1987
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Stimulation by ATP of proinsulin to insulin conversion in isolated rat pancreatic islet secretory granules. Association with the ATP-dependent proton pump Rhodes, C. J.; Lucas, C. A.; Mutkoski, R. L.; Orci, Lelio; Halban, Philippe A. 1987
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Substrate specificity of proinsulin conversion in the constitutive pathway of transfected FAO (hepatoma) cells Vollenweider, F.; Irminger, J. C.; Halban, Philippe A. 1993
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Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells Wang, Haiyan; Iezzi, M.; Theander, Sten; Antinozzi, P. A.; ... Wollheim, Claes 2005