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 TitleAuthors / EditorsDate
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 A focus on the role of Pax4 in mature pancreatic islet beta-cell expansion and survival in health and disease Brun, Thierry; Gauthier, Benoît 2008
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 Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1 Schwitzgebel Luscher, Valérie; Mamin, Aline; Brun, Thierry; Ritz, Beate Andréa; ... Philippe, Jacques 2003
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 AMPK profiling in rodent and human pancreatic beta-cells under nutrient-rich metabolic stress Brun, Thierry; Jimenez-Sanchez, Cécilia; Madsen, Jesper Grud Skat; Hadadi, Noushin; ... Maechler, Pierre 2020
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 Beta-cell mitochondrial carriers and the diabetogenic stress response Brun, Thierry; Maechler, Pierre 2016
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 Changes in mitochondrial carriers exhibit stress-specific signatures in INS-1Eβ-cells exposed to glucose versus fatty acids Brun, Thierry; Scarcia, Pasquale; Li, Ning; Gaudet, Pascale; ... Maechler, Pierre 2013
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 Chronic fructose renders pancreatic beta-cells hyper-responsive to glucose-stimulated insulin secretion through extracellular ATP signaling Bartley, Clarissa; Brun, Thierry; Oberhauser, Lucie; Grimaldi, Mariagrazia; ... Maechler, Pierre 2019
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 Diabetogenic milieus induce specific changes in mitochondrial transcriptome and differentiation of human pancreatic islets Brun, Thierry; Li, Ning; Jourdain, Alexis; Gaudet, Pascale; ... Maechler, Pierre 2015
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 Ectopic expression of the beta-cell specific transcription factor Pdx1 inhibits glucagon gene transcription Ritz-Laser, B.; Gauthier, B. R.; Estreicher, A.; Mamin, Aline; ... Philippe, Jacques 2003
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 Glucolipotoxicity promotes the capacity of the glycerolipid/NEFA cycle supporting the secretory response of pancreatic beta cells Oberhauser, Lucie; Jiménez-Sánchez, Cecilia; Madsen, Jesper Grud Skat; Duhamel, Dominique; ... Maechler, Pierre 2022
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 In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice Hu He, Kai Hui; Lorenzo, Petra I; Brun, Thierry; Jimenez Moreno, Carmen M; ... Gauthier, Benoît 2011
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 L'exposition des cellules bêta au fructose potentialise la sécrétion d'insuline via une signalisation par l'ATP Brun, Thierry; Bartley, Clarissa; Maechler, Pierre 2019
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 Mitochondrial carriers regulating insulin secretion profiled in human islets upon metabolic stress Jiménez-Sánchez, Cecilia; Brun, Thierry; Maechler, Pierre 2020
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 Mitochondrial dysfunction in pancreatic β cells Supale, Sachin; Li, Ning; Brun, Thierry; Maechler, Pierre 2012
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 NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion Li, Ning; Li, Bin; Brun, Thierry; Deffert-Delbouille, Christine; ... Maechler, Pierre 2012
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 Palmitate and oleate modify membrane fluidity and kinase activities of INS-1E β-cells alongside altered metabolism-secretion coupling Oberhauser, Lucie; Granziera, Sabrina; Colom Diego, Adai; Goujon, Antoine; ... Maechler, Pierre 2020
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 Peroxisome proliferator-activated receptor alpha (PPARalpha) protects against oleate-induced INS-1E beta cell dysfunction by preserving carbohydrate metabolism Frigerio, Francesca; Brun, Thierry; Bartley, C.; Usardi, A.; ... Maechler, Pierre 2010
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 Regulation of acetyl-CoA carboxylase gene expression by nutrients in the pancreatic β-cell Brun, Thierry 1994
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 Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism Vetterli, Laurene Marine; Brun, Thierry; Giovannoni, Laurianne; Bosco, Domenico; Maechler, Pierre 2011
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 Role of mitochondria in beta-cell function and dysfunction Maechler, Pierre; Li, Ning; Casimir, Marina Shamini; Vetterli, Laurene Marine; ... Brun, Thierry 2010
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 The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1 Brun, Thierry; He, Kai Hui Hu; Lupi, Roberto; Boehm, Bernhard; ... Gauthier, Benoît 2008
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