| | Title | Authors / Editors | Date |
|
unige:851 |
A focus on the role of Pax4 in mature pancreatic islet beta-cell expansion and survival in health and disease |
Brun, Thierry; Gauthier, Benoît |
2008 |
|
unige:55257 |
Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1 |
Schwitzgebel Luscher, Valérie; Mamin, Aline; Brun, Thierry; Ritz, Beate Andréa; ... Philippe, Jacques |
2003 |
|
unige:137262 |
AMPK profiling in rodent and human pancreatic beta-cells under nutrient-rich metabolic stress |
Brun, Thierry; Jimenez-Sanchez, Cécilia; Madsen, Jesper Grud Skat; Hadadi, Noushin; ... Maechler, Pierre |
2020 |
|
unige:89722 |
Beta-cell mitochondrial carriers and the diabetogenic stress response |
Brun, Thierry; Maechler, Pierre |
2016 |
|
unige:36468 |
Changes in mitochondrial carriers exhibit stress-specific signatures in INS-1Eβ-cells exposed to glucose versus fatty acids |
Brun, Thierry; Scarcia, Pasquale; Li, Ning; Gaudet, Pascale; ... Maechler, Pierre |
2013 |
|
unige:116616 |
Chronic fructose renders pancreatic beta-cells hyper-responsive to glucose-stimulated insulin secretion through extracellular ATP signaling |
Bartley, Clarissa; Brun, Thierry; Oberhauser, Lucie; Grimaldi, Mariagrazia; ... Maechler, Pierre |
2019 |
|
unige:77865 |
Diabetogenic milieus induce specific changes in mitochondrial transcriptome and differentiation of human pancreatic islets |
Brun, Thierry; Li, Ning; Jourdain, Alexis; Gaudet, Pascale; ... Maechler, Pierre |
2015 |
|
unige:25005 |
In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice |
Hu He, Kai Hui; Lorenzo, Petra I; Brun, Thierry; Jimenez Moreno, Carmen M; ... Gauthier, Benoît |
2011 |
|
unige:116614 |
L’exposition des cellules bêta au fructose potentialise la sécrétion d’insuline via une signalisation par l’ATP |
Brun, Thierry; Bartley, Clarissa; Maechler, Pierre |
2019 |
|
unige:145502 |
Mitochondrial carriers regulating insulin secretion profiled in human islets upon metabolic stress |
Jiménez-Sánchez, Cecilia; Brun, Thierry; Maechler, Pierre |
2020 |
|
unige:28014 |
Mitochondrial dysfunction in pancreatic β cells |
Supale, Sachin; Li, Ning; Brun, Thierry; Maechler, Pierre |
2012 |
|
unige:28039 |
NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion |
Li, Ning; Li, Bin; Brun, Thierry; Deffert-Delbouille, Christine; ... Maechler, Pierre |
2012 |
|
unige:127987 |
Palmitate and oleate modify membrane fluidity and kinase activities of INS-1E β-cells alongside altered metabolism-secretion coupling |
Oberhauser, Lucie; Granziera, Sabrina; Colom Diego, Adai; Goujon, Antoine; ... Maechler, Pierre |
2020 |
|
unige:20682 |
Peroxisome proliferator-activated receptor alpha (PPARalpha) protects against oleate-induced INS-1E beta cell dysfunction by preserving carbohydrate metabolism |
Frigerio, Francesca; Brun, Thierry; Bartley, C.; Usardi, A.; ... Maechler, Pierre |
2010 |
|
unige:104839 |
Regulation of acetyl-CoA carboxylase gene expression by nutrients in the pancreatic β-cell |
Brun, Thierry |
1994 |
|
unige:25240 |
Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism |
Vetterli, Laurene Marine; Brun, Thierry; Giovannoni, Laurianne; Bosco, Domenico; Maechler, Pierre |
2011 |
|
unige:20510 |
Role of mitochondria in beta-cell function and dysfunction |
Maechler, Pierre; Li, Ning; Casimir, Marina Shamini; Vetterli, Laurene Marine; ... Brun, Thierry |
2010 |
|
unige:765 |
The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1 |
Brun, Thierry; He, Kai Hui Hu; Lupi, Roberto; Boehm, Bernhard; ... Gauthier, Benoît |
2008 |
|
unige:34542 |
The diabetes-linked transcription factor PAX4 promotes {beta}-cell proliferation and survival in rat and human islets |
Brun, Thierry; Franklin, Isobel; St-Onge, Luc; Biason-Lauber, Anna; ... Gauthier, Benoît |
2004 |
|
unige:33453 |
The transcription factor PAX4 acts as a survival gene in INS-1E insulinoma cells |
Brun, Thierry; Duhamel, Dominique; Hu He, Kaihui; Wollheim, Claes; Gauthier, Benoît |
2007 |
Brun, Thierry
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