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A New Anti-CXCR4 Antibody That Blocks the CXCR4/SDF-1 Axis and Mobilizes Effector Cells Broussas, Matthieu; Boute, Nicolas; Akla, Barbara; Berger, Sven; ... Klinguer-Hamour, Christine 2016
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An Online Four-Dimensional HIC×SEC-IM×MS Methodology for Proof-of-Concept Characterization of Antibody Drug Conjugates Ehkirch, Antony; D'Atri, Valentina; Rouviere, Florent; Hernandez-Alba, Oscar; ... Cianferani, Sarah 2018
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Analysis of antibody-drug conjugates by comprehensive on-line two-dimensional hydrophobic interaction chromatography x reversed phase liquid chromatography hyphenated to high resolution mass spectrometry. I − Optimization of separation conditions Sarrut, Morgane; Corgier, Amélie; Fekete, Szabolcs; Guillarme, Davy; ... Heinisch, Sabine 2016
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Analysis of recombinant monoclonal antibodies in hydrophilicinteraction chromatography: A generic method developmentapproach Bobaly, Balazs; D'Atri, Valentina; Beck, Alain; Guillarme, Davy; Fekete, Szabolcs 2017
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Anticorps monoclonaux biosimilaires Beck, Alain; Guillarme, Davy; Fleury-Souverain, Sandrine; Bodier-Montagutelli, Elsa; Respaud, Renaud 2019
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Characterization of 30 therapeutic antibodies and related products by size exclusion chromatography: Feasibility assessment for future mass spectrometry hyphenation Goyon, Alexandre; D'Atri, Valentina; Colas, Olivier; Fekete, Szabolcs; ... Guillarme, Davy 2017
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Characterization of an antibody-drug conjugate by hydrophilic interaction chromatography coupled to mass spectrometry D'Atri, Valentina; Fekete, Szabolcs; Stoll, Dwight; Lauber, Matthew; ... Guillarme, Davy 2018
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Characterizing various monoclonal antibodies with milder reversed phase chromatography conditions Bobaly, Balazs; D'Atri, Valentina; Lauber, Matthew; Beck, Alain; ... Fekete, Szabolcs 2018
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Comparison of originator and biosimilar therapeutic monoclonal antibodies using comprehensive two-dimensional liquid chromatography coupled with time-of-flight mass spectrometry Sorensen, Matthew; Harmes, David C.; Stoll, Dwight R.; Staples, Gergory O.; ... Beck, Alain 2016
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Comprehensive study on the effects of sodium and potassiumadditives in size exclusion chromatographic separations of proteinbiopharmaceuticals Goyon, Alexandre; Beck, Alain; Veuthey, Jean-Luc; Guillarme, Davy; Fekete, Szabolcs 2017
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Coupling non-denaturing chromatography to mass spectrometry for the characterization of monoclonal antibodies and related products Farsang, Evelin; Guillarme, Davy; Veuthey, Jean-Luc; Beck, Alain; ... Fekete, Szabolcs 2020
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Current possibilities of liquid chromatography for the characterization of antibody-drug conjugates Bobaly, Balazs; Fleury, Sandrine; Beck, Alain; Veuthey, Jean-Luc; ... Fekete, Szabolcs 2018
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Cutting-edge multi-level analytical and structural characterization of antibody-drug conjugates: present and future Beck, Alain; D'Atri, Valentina; Ehkirch, Anthony; Fekete, Szabolcs; ... Cianférani, Sarah 2019
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Determination of size variants by CE-SDS for approved therapeutic antibodies: Key implications of subclasses and light chain specificities Wagner, Elsa; Colas, Olivier; Chenu, Stéphane; Goyon, Alexandre; ... Beck, Alain 2020
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Development of a fast workflow to screen the charge variants of therapeutic antibodies Wagner-Rousset, Elsa; Fekete, Szabolcs; Morel-Chevillet, Laura; Colas, Olivier; ... Beck, Alain 2017
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Development of Comprehensive Online Two-Dimensional Liquid Chromatography/Mass Spectrometry Using Hydrophilic Interaction and Reversed-Phase Separations for Rapid and Deep Profiling of Therapeutic Antibodies Stoll, Dwight R.; Harmes, David C.; Staples, Gregory O.; Potter, Oscar G.; ... Beck, Alain 2018
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Drug Loading and Distribution of ADCs After Reduction or IdeS Digestion and Reduction Wagner-Rousset, Elsa; Colas, Olivier; François, Yannis-Nicolas; Heinisch, Sabine; ... Beck, Alain 2020
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Glycan-Mediated Technology for Obtaining Homogeneous Site-Specific Conjugated Antibody-Drug Conjugates: Synthesis and Analytical Characterization by Using Complementary Middle-up LC/HRMS Analysis Duivelshof, Bastiaan; Deslignière, Evolène; Hernandez-Alba, Oscar; Ehkirch, Anthony; ... D'Atri, Valentina 2020
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Glycosylation of biosimilars: Recent advances in analytical characterization and clinical implications Duivelshof, Bastiaan; Jiskoot, Wim; Beck, Alain; Veuthey, Jean-Luc; ... D'Atri, Valentina 2019
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High-resolution separation of monoclonal antibodies mixtures and their charge variants by an alternative and generic CZE method Goyon, Alexandre; Francois, Yannis Nicolas; Colas, Olivier; Beck, Alain; ... Guillarme, Davy 2018
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