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An Online Four-Dimensional HIC×SEC-IM×MS Methodology for Proof-of-Concept Characterization of Antibody Drug Conjugates Ehkirch, Antony; D'Atri, Valentina; Rouviere, Florent; Hernandez-Alba, Oscar; ... Cianferani, Sarah 2018
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Characterization of 30 therapeutic antibodies and related products by size exclusion chromatography: Feasibility assessment for future mass spectrometry hyphenation Goyon, Alexandre; D'Atri, Valentina; Colas, Olivier; Fekete, Szabolcs; ... Guillarme, Davy 2017
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Comprehensive study on the effects of sodium and potassiumadditives in size exclusion chromatographic separations of proteinbiopharmaceuticals Goyon, Alexandre; Beck, Alain; Veuthey, Jean-Luc; Guillarme, Davy; Fekete, Szabolcs 2017
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Determination of size variants by CE-SDS for approved therapeutic antibodies: Key implications of subclasses and light chain specificities Wagner, Elsa; Colas, Olivier; Chenu, Stéphane; Goyon, Alexandre; ... Beck, Alain 2020
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Development of a lc–ms/ms method for the determination of isomeric glutamyl peptides in food ingredients Desfontaine, Vincent; Goyon, Alexandre; Veuthey, Jean-Luc; Charve, Joséphine; Guillarme, Davy 2018
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Development of an innovative salt-mediated pH gradient cation exchange chromatography method for the characterization of therapeutic antibodies Goyon, Alexandre; McDonald, Daniel; Fekete, Szabolcs; Guillarme, Davy; Stella, Cinzia 2020
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Évaluation de méthodes chromatographiques et électrophorétiques pour la caractérisation de protéines thérapeutiques Goyon, Alexandre 2019
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Extending the limits of size exclusion chromatography: Simultaneousseparation of free payloads and related species from antibody drugconjugates and their aggregates Goyon, Alexandre; Sciascera, Luca; Clarke, Adrien; Guillarme, Davy; Pell, Reinhard 2018
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From proof of concept to the routine use of an automated and robust multi-dimensional liquid chromatography mass spectrometry workflow applied for the charge variant characterization of therapeutic antibodies Goyon, Alexandre; Dai, Lu; Chen, Tao; Wei, Bingchuan; ... Stella, Cinzia 2020
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High-resolution separation of monoclonal antibodies mixtures and their charge variants by an alternative and generic CZE method Goyon, Alexandre; Francois, Yannis Nicolas; Colas, Olivier; Beck, Alain; ... Guillarme, Davy 2018
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Non-invasive targeted iontophoretic delivery of cetuximab to skin Lapteva, Maria; Sallam, Marwa A.; Goyon, Alexandre; Guillarme, Davy; ... Kalia, Yogeshvar 2020
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Protocols for the analytical characterization of therapeutic monoclonal antibodies. I - Non-denaturing chromatographic techniques Goyon, Alexandre; D'Atri, Valentina; Bobaly, Balazs; Wagner-Rousset, Elsa; ... Guillarme, Davy 2017
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Protocols for the analytical characterization of therapeutic monoclonal antibodies. II – Enzymatic and chemical sample preparation Bobaly, Balazs; Goyon, Alexandre; D'Atri, Valentina; Colas, Olivier; ... Guillarme, Davy 2017
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Protocols for the analytical characterization of therapeutic monoclonal antibodies. III – Denaturing chromatographic techniques hyphenated to mass spectrometry D'Atri, Valentina; Goyon, Alexandre; Bobaly, Balazs; Beck, Alain; ... Guillarme, Davy 2018
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Size Exclusion Chromatography of Protein Biopharmaceuticals: Past, Present and Future Fekete, Szabolcs; Goyon, Alexandre; Veuthey, Jean-Luc; Guillarme, Davy 2018
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Streamlined Characterization of an Antibody–Drug Conjugate by Two-Dimensional and Four-Dimensional Liquid Chromatography/Mass Spectrometry Goyon, Alexandre; Kim, Michael; Dai, Lu; Cornell, Christopher; ... Stella, Cinzia 2019
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The importance of system band broadening in modern size exclusion chromatography Goyon, Alexandre; Guillarme, Davy; Fekete, Szabolcs 2017
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Unraveling the mysteries of modern size exclusion chromatography – the way to achieve confident characterization of therapeutic proteins Goyon, Alexandre; Fekete, Szabolcs; Beck, Alain; Veuthey, Jean-Luc; Guillarme, Davy 2018