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Selective affinity-based probe for oncogenic kinases suitable for live cell imaging Zambaldo, Claudio; Sadhu, Kalyan K.; Karthikeyan, Ganesan; Barluenga, Sofia; ... Winssinger, Nicolas 2013
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Self-Assembled Antibody Multimers through Peptide Nucleic Acid Conjugation Kazane, Stephanie A.; Axup, Jun Y.; Kim, Chan Hyuk; Ciobanu, Mihai; ... Smider, Vaughn V. 2013
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Discovery of an entropically-driven small molecule streptavidin binder from nucleic acid-encoded libraries Daguer, Jean-Pierre; Ciobanu, Mihai; Barluenga, Sofia; Winssinger, Nicolas 2012
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Synthesis of deguelin–biotin conjugates and investigation into deguelin’s interactions Garcia, José; Barluenga, Sofia; Gorska, Katarzyna; Sasse, Florenz; Winssinger, Nicolas 2012
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Expanding the Scope of PNA-Encoded Synthesis (PES): Mtt-Protected PNA Fully Orthogonal to Fmoc Chemistry and a Broad Array of Robust Diversity-Generating Reactions Chouikhi, Dalila; Ciobanu, Mihai; Zambaldo, Claudio; Duplan, Vincent; ... Winssinger, Nicolas 2012
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Asymmetric Synthesis of Pochonin E and F, Revision of Their Proposed Structure, and Their Conversion to Potent Hsp90 Inhibitors Karthikeyan, Ganesan; Zambaldo, Claudio; Barluenga, Sofia; Zoete, Vincent; ... Winssinger, Nicolas 2012
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Diversity-Oriented Synthesis of Diverse Polycyclic Scaffolds Inspired by the Logic of Sesquiterpene Lactones Biosynthesis Valot, Gaëlle; Garcia, José; Duplan, Vincent; Serba, Christelle; ... Winssinger, Nicolas 2012
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Selection of a synthetic glycan oligomer from a library of DNA-templated fragments against DC-SIGN and inhibition of HIV gp120 binding to dendritic cells Ciobanu, Mihai; Huang, Kuo-Ting; Daguer, Jean-Pierre; Barluenga, Sofia; ... Winssinger, Nicolas 2011
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DNA-templated release of functional molecules with an azide-reduction-triggered immolative linker Gorska, Katarzyna; Manicardi, Alex; Barluenga, Sofia; Winssinger, Nicolas 2011
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DNA-templated combinatorial assembly of small molecule fragments amenable to selection/amplification cycles Daguer, Jean Pierre; Ciobanu, Mihai; Alvarez, Susana; Barluenga, Sofia; Winssinger, Nicolas 2011
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Cysteine Mapping in Conformationally Distinct Kinase Nucleotide Binding Sites: Application to the Design of Selective Covalent Inhibitors Leproult, Emeline; Barluenga, Sofia; Moras, Dino; Wurtz, Jean-Marie; Winssinger, Nicolas 2011
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Combinatorial Self-Assembly of Glycan Fragments into Microarrays Huang, Kuo-Ting; Gorska, Katarzyna; Alvarez, Susana; Barluenga, Sofia; Winssinger, Nicolas 2011
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Metathesis Reactions in Solid-Phase Organic Synthesis Barluenga, Sofia; Dakas, Pierre-Yves; Jogireddy, Rajamalleswaramma; Valot, Gaële; Winssinger, Nicolas 2010
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Clickable peptide nucleic acids (cPNA) with tunable affinity Chouikhi, Dalila; Barluenga, Sofia; Winssinger, Nicolas 2010
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Concise Modular Asymmetric Synthesis of Deguelin, Tephrosin and Investigation into Their Mode of Action Garcia, José; Barluenga, Sofia; Beebe, Kristin; Neckers, Len; Winssinger, Nicolas 2010
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In Vivo Efficacy of Natural Product-Inspired Irreversible Kinase Inhibitors Barluenga, Sofia; Jogireddy, Rajamalleswaramma; Koripelly, Girish K.; Winssinger, Nicolas 2010
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Molecular Editing of Kinase-Targeting Resorcylic Acid Lactones (RAL): Fluoroenone RAL Jogireddy, Rajamalleswaramma; Barluenga, Sofia; Winssinger, Nicolas 2010
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The HSP90 binding mode of a radicicol-like E-oxime determined by docking, binding free energy estimations, and NMR 15N chemical shifts Spichty, Martin; Taly, Antoine; Hagn, Franz; Kessler, Horst; ... Karplus, Martin 2009
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Synthesis of pochoxime prodrugs as potent HSP90 inhibitors Wang, Cuihua; Barluenga, Sofia; Koripelly, Girish K.; Fontaine, Jean-Gonzague; ... Winssinger, Nicolas 2009
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Hsp90 Inhibition with Resorcylic Acid Lactones (RALs) Winssinger, Nicolas; Fontaine, Jean-Gonzague; Barluenga, Sofia 2009
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High-Throughput Synthesis of Natural Products Winssinger, Nicolas; Barluenga, Sofia; Dakas, Pierre-Yves 2009
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Inhibition of HSP90 with Pochoximes: SAR and Structure-Based Insights Barluenga, Sofia; Fontaine, Jean-Gonzague; Wang, Cuihua; Aouadi, Kais; ... Winssinger, Nicolas 2009
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Synthesis of a Resorcylic Acid Lactone (RAL) Library Using Fluorous-Mixture Synthesis and Profile of its Selectivity Against a Panel of Kinases Jogireddy, Rajamalleswaramma; Dakas, Pierre-Yves; Valot, Gaëlle; Barluenga, Sofia; Winssinger, Nicolas 2009
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Divergent Syntheses of Resorcylic Acid Lactones: L-783277, LL-Z1640-2, and Hypothemycin Dakas, Pierre-Yves; Jogireddy, Rajamalleswaramma; Valot, Gaëlle; Barluenga, Sofia; Winssinger, Nicolas 2009
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Chemical Technologies: Probing Biology with Small Molecules Winssinger, Nicolas; Pianowski, Zbigniew; Barluenga, Sofia 2008
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Resorcylic acid lactones: A pluripotent scaffold with therapeutic potential Barluenga, Sofia; Dakas, Pierre-Yves; Boulifa, Mehdi; Moulin, Emilie; Winssinger, Nicolas 2008
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Diversity-oriented synthesis of novel polycyclic scaffolds using polymer-bound reagents García-Cuadrado, Domingo; Barluenga, Sofia; Winssinger, Nicolas 2008
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Divergent Synthesis of a Pochonin Library Targeting HSP90 and In Vivo Efficacy of an Identified Inhibitor Barluenga, Sofia; Wang, Cuihua; Fontaine, Jean-Gonzague; Aouadi, Kaïss; ... Winssinger, Nicolas 2008
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Chemistry and biology of resorcylic acid lactones Winssinger, Nicolas; Barluenga, Sofia 2007
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Modular Synthesis of Radicicol A and Related Resorcylic Acid Lactones, Potent Kinase Inhibitors Dakas, Pierre-Yves; Barluenga, Sofia; Totzke, Frank; Zirrgiebel, Ute; Winssinger, Nicolas 2007
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Modular Asymmetric Synthesis of Aigialomycin D, a Kinase-Inhibitory Scaffold Barluenga, Sofia; Dakas, Pierre-Yves; Ferandin, Yoan; Meijer, Laurent; Winssinger, Nicolas 2006
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Diversity-Oriented Synthesis of Pochonins and Biological Evaluation against a Panel of Kinases Moulin, Emilie; Barluenga, Sofia; Totzke, Frank; Winssinger, Nicolas 2006
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Concise Synthesis of Pochonin A, an HSP90 Inhibitor Moulin, Emilie; Barluenga, Sofia; Winssinger, Nicolas 2005
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Solution- and Solid-Phase Synthesis of Radicicol (Monorden) and Pochonin C Barluenga, Sofia; Moulin, Emilie; Lopez, Pilar; Winssinger, Nicolas 2005
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Design, Synthesis, and Biological Evaluation of HSP90 Inhibitors Based on Conformational Analysis of Radicicol and Its Analogues Moulin, Emilie; Zoete, Vincent; Barluenga, Sofia; Karplus, Martin; Winssinger, Nicolas 2005
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Modular Asymmetric Synthesis of Pochonin C Barluenga, Sofia; Lopez, Pilar; Moulin, Emilie; Winssinger, Nicolas 2004
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Synthesis of the macrocyclic core of sanglifehrin A Nicolaou, K. C.; Ohshima, Takashi; Murphy, Fiona; Barluenga, Sofia; ... Winssinger, Nicolas 1999
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Polymer-supported selenium reagents for organic synthesis Nicolaou, K. C.; Pastor, Joaquín; Barluenga, Sofia; Winssinger, Nicolas 1998