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 TitleAuthors / EditorsDate
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Overcoming the neonatal limitations of inducing germinal centers through liposome-based adjuvants including c-type lectin agonists trehalose dibehenate or curdlan Vono, Maria; Eberhardt, Christiane Sigrid; Mohr, Elodie; Auderset, Floriane; ... Siegrist, Claire-Anne 2018
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The Nucleoprotein Is Required for Lymphocytic Choriomeningitis Virus-Based Vaccine Vector Immunogenicity Darbre, Stéphanie; Johnson, Susan; Kallert, Sandra; Lambert, Paul Henri; ... Pinschewer, Daniel 2015
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Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection Sommerstein, Rami; Flatz, Lukas Roland; Remy, Mélissa; Malinge, Pauline; ... Pinschewer, Daniel 2015
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Protective efficacy of individual CD8+ T cell specificities in chronic viral infection Johnson, Susan; Bergthaler, Andréas; Graw, Frederik; Flatz, Lukas Roland; ... Pinschewer, Daniel 2015
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Needle-free and adjuvant-free epicutaneous boosting of pertussis immunity: Preclinical proof of concept Mastelic-Gavillet, Beatris; Mondoulet, Lucie; Dhelft, Véronique; Eberhardt, Christiane Sigrid; ... Siegrist, Claire-Anne 2015
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MF59 Mediates Its B Cell Adjuvanticity by Promoting T Follicular Helper Cells and Thus Germinal Center Responses in Adult and Early Life Mastelic-Gavillet, Beatris; Eberhardt, Christiane Sigrid; Auderset, Floriane; Castellino, Flora; ... Siegrist, Claire-Anne 2015
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Functional limitations of plasmacytoid dendritic cells limit type I interferon, T cell responses and virus control in early life Belnoue, Elodie; Fontannaz, Paola; Rochat, Anne-Françoise; Tougne, Chantal; ... Siegrist, Claire-Anne 2013
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Synchronization of dendritic cell activation and antigen exposure is required for the induction of Th1/Th17 responses Kamath, Arun; Mastelic-Gavillet, Beatris; Christensen, Dennis; Rochat, Anne-Françoise; ... Siegrist, Claire-Anne 2012
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Homing and adhesion patterns determine the cellular composition of the bone marrow plasma cell niche Belnoue, Elodie; Tougne, Chantal; Rochat, Anne-Françoise; Lambert, Paul Henri; ... Siegrist, Claire-Anne 2012
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A cationic vaccine adjuvant based on a saturated quaternary ammonium lipid have different in vivo distribution kinetics and display a distinct CD4 T cell-inducing capacity compared to its unsaturated analog Christensen, Dennis; Henriksen-Lacey, Malou; Kamath, Arun; Lindenstrøm, Thomas; ... Agger, Else Marie 2012
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Environmental and T cell-intrinsic factors limit the expansion of neonatal follicular T helper cells but may be circumvented by specific adjuvants Mastelic-Gavillet, Beatris; Kamath, Arun; Fontannaz, Paola; Tougne, Chantal; ... Siegrist, Claire-Anne 2012
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Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity Flatz, Lukas; Hegazy, A. N.; Bergthaler, Andréas; Verschoor, Admar; ... Pinschewer, Daniel 2010
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Mode of action of adjuvants: implications for vaccine safety and design Mastelic-Gavillet, Beatris; Ahmed, Sohail; Egan, William M.; Del Giudice, Giuseppe; ... Lambert, Paul Henri 2010
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Frequent failure of adolescent booster responses to tetanus toxoid despite infant immunization: waning of infancy-induced immune memory? Posfay Barbe, Clara; Kobela, Marie; Sottas, Cédric Ernest; Grillet, Stéphane; ... Siegrist, Claire-Anne 2010
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Coalition of advocates to vaccinate of Western European citizens aged 60 years and older Michel, Jean-Pierre; Chidiac, Christian; Grubeck-Loebenstein, Beatrix; Johnson, Robert W.; ... Werner, Hans-Martin 2009
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Global safety of vaccines: strengthening systems for monitoring, management and the role of GACVS Autran, Brigitte; Asturias, Edwin J.; Evans, Stephen; Hartigan-Go, Kenneth; ... Wood, David 2009
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Advocating vaccination of adults aged 60 years and older in Western Europe: statement by the Joint Vaccine Working Group of the European Union Geriatric Medicine Society and the International Association of Gerontology and Geriatrics-European Region Michel, Jean-Pierre; Chidiac, Christian; Grubeck-Loebenstein, Beatrix; Johnson, Robert W.; ... Werner, Hans-Martin 2009
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A liposome-based mycobacterial vaccine induces potent adult and neonatal multifunctional T cells through the exquisite targeting of dendritic cells Kamath, Arun; Rochat, Anne-Françoise; Christensen, Dennis; Agger, Else Marie; ... Siegrist, Claire-Anne 2009
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Intradermal vaccine delivery: will new delivery systems transform vaccine administration? Lambert, Paul Henri; Laurent, Philippe E. 2008
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Protective anti-mycobacterial T cell responses through exquisite in vivo activation of vaccine-targeted dendritic cells Kamath, Arun; Valenti, Mario Paolo; Rochat, Anne-Françoise; Agger, Else Marie; ... Siegrist, Claire-Anne 2008
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Adult-like anti-mycobacterial T cell and in vivo dendritic cell responses following neonatal immunization with Ag85B-ESAT-6 in the IC31 adjuvant Kamath, Arun; Rochat, Anne-Françoise; Valenti, Mario Paolo; Agger, Else Marie; ... Siegrist, Claire-Anne 2008
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Protracted course of lymphocytic choriomeningitis virus WE infection in early life: induction but limited expansion of CD8+ effector T cells and absence of memory CD8+ T cells Belnoue, Elodie; Fontannaz, Paola; Grillet, Stéphane; Lambert, Paul Henri; Siegrist, Claire-Anne 2007
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Predominant influence of environmental determinants on the persistence and avidity maturation of antibody responses to vaccines in infants Marchant, Arnaud; Pihlgren Bosch, Maria Astrid Louise; Goetghebuer, Tessa; Weiss, Helen A; ... Siegrist, Claire-Anne 2006
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Reduced ability of neonatal and early-life bone marrow stromal cells to support plasmablast survival Pihlgren Bosch, Maria Astrid Louise; Friedli, Mathieu; Tougne, Chantal; Rochat, Anne-Françoise; ... Siegrist, Claire-Anne 2006
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Can successful vaccines teach us how to induce efficient protective immune responses? Lambert, Paul Henri; Liu, Margaret; Siegrist, Claire-Anne 2005
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The immunomodulating properties of human respiratory syncytial virus and immunostimulating complexes containing Quillaja saponin components QH-A, QH-C and ISCOPREP703 Hu, Ke-Fei; Regner, Matthias; Siegrist, Claire-Anne; Lambert, Paul Henri; ... Morein, Bror 2005
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Vaccine safety controversies and the future of vaccination programs François, Guido; Duclos, Philippe; Margolis, Harold; Lavanchy, Daniel; ... Van Damme, Pierre 2005
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Safety and efficacy of immune-stimulating complex-based antigen delivery systems for neonatal immunisation against respiratory syncytial virus infection Regner, Matthias; Culley, Fiona; Fontannaz, Paola; Hu, Kefei; ... Siegrist, Claire-Anne 2004
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Co-administration of CpG oligonucleotides enhances the late affinity maturation process of human anti-hepatitis B vaccine response Siegrist, Claire-Anne; Pihlgren Bosch, Maria Astrid Louise; Tougne, Chantal; Efler, Sue M; ... Lambert, Paul Henri 2004
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Influence of complement C3 amount on IgG responses in early life: immunization with C3b-conjugated antigen increases murine neonatal antibody responses Pihlgren Bosch, Maria Astrid Louise; Fulurija, Alma; Villiers, Marie-Bernadette; Tougne, Chantal; ... Siegrist, Claire-Anne 2004
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Hepatitis B immunisation induces higher antibody and memory Th2 responses in new-borns than in adults Ota, Martin OC; Vekemans, Johan; Schlegel Heueter, Susanna; Fielding, Katherine; ... Marchant, Arnaud 2004
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A global perspective on vaccine safety and public health: the Global Advisory Committee on Vaccine Safety Folb, Peter I; Bernatowska, Ewa; Chen, Robert; Clemens, John; ... Wimalaratne, Omala 2004
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Partial activation of neonatal CD11c+ dendritic cells and induction of adult-like CD8+ cytotoxic T cell responses by synthetic microspheres Regner, Matthias; Martinez, Javier; Belnoue, Elodie; Sun, Cheng Min; ... Siegrist, Claire-Anne 2004
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Unresponsiveness to lymphoid-mediated signals at the neonatal follicular dendritic cell precursor level contributes to delayed germinal center induction and limitations of neonatal antibody responses to T-dependent antigens Pihlgren Bosch, Maria Astrid Louise; Tougne, Chantal; Bozzotti, Paola; Fulurija, Alma; ... Siegrist, Claire-Anne 2003
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CpG-motifs enhance initial and sustained primary tetanus-specific antibody secreting cell responses in spleen and bone marrow, but are more effective in adult than in neonatal mice Pihlgren Bosch, Maria Astrid Louise; Tougne, Chantal; Schallert, Nadine; Bozzotti, Paola; ... Siegrist, Claire-Anne 2003
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CD4-independent protective cytotoxic T cells induced in early life by a non-replicative delivery system based on virus-like particles Martinez, Javier; Regner, Matthias; Kovarik, Jiri; Zarei Haller, Shohreh; ... Siegrist, Claire-Anne 2003
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Generation of adult-like antibody avidity profiles after early-life immunization with protein vaccines Schallert, Nadine; Pihlgren Bosch, Maria Astrid Louise; Kovarik, Jiri; Roduit, Caroline Monique; ... Lambert, Paul Henri 2002
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Immunogenicity and protective efficacy of neonatal vaccination against Bordetella pertussis in a murine model: evidence for early control of pertussis Roduit, Caroline Monique; Bozzotti, Paola; Mielcarek, Nathalie; Lambert, Paul Henri; ... Siegrist, Claire-Anne 2002
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Influence of Mycobacterium bovis bacillus Calmette-Guérin on antibody and cytokine responses to human neonatal vaccination Ota, Martin O C; Vekemans, Johan; Schlegel Heueter, Susanna; Fielding, Katherine; ... Marchant, Arnaud 2002
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Delayed and deficient establishment of the long-term bone marrow plasma cell pool during early life Pihlgren Bosch, Maria Astrid Louise; Schallert, N; Tougne, Chantal; Bozzotti, P; ... Siegrist, Claire-Anne 2001
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Induction of adult-like antibody, Th1, and CTL responses to measles hemagglutinin by early life murine immunization with an attenuated vaccinia-derived NYVAC(K1L) viral vector Kovarik, Jiri; Gaillard, Muriel; Martinez, Javier; Bozzotti, P; ... Siegrist, Claire-Anne 2001
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Adjuvant effects of CpG oligodeoxynucleotides on responses against T-independent type 2 antigens Kovarik, Jiri; Bozzotti, P; Tougne, Chantal; Davis, HL; ... Siegrist, Claire-Anne 2001
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CpG oligodeoxynucleotides can circumvent the Th2 polarization of neonatal responses to vaccines but may fail to fully redirect Th2 responses established by neonatal priming Kovarik, Jiri; Bozzotti, P; Love-Homan, L; Pihlgren Bosch, Maria Astrid Louise; ... Siegrist, Claire-Anne 1999
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Combining DNA and protein vaccines for early life immunization against respiratory syncytial virus in mice Martinez, Javier; Lin, Xiao; Kovarik, Jiri; Klein, Michael Joséph; ... Siegrist, Claire-Anne 1999
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Antigen-Presentation Systems, Immunomodulators, and Immune Responses to Vaccines Siegrist, Claire-Anne; Lambert, Paul Henri 1999
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Influence of maternal antibodies on vaccine responses: inhibition of antibody but not T cell responses allows successful early prime-boost strategies in mice Siegrist, Claire-Anne; Barrios-Janko, Christy; Martinez, Javier; Brandt, Christian; ... Lambert, Paul Henri 1998
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Induction of neonatal TH1 and CTL responses by live viral vaccines: a role for replication patterns within antigen presenting cells? Siegrist, Claire-Anne; Saddallah, F; Tougne, Chantal; Martinez, Javier; ... Lambert, Paul Henri 1998
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Immunity in early life : an introduction [Proceedings of the International Symposium on Immunity in Early Life. Annecy, France, 17-19 November 1997] Siegrist, Claire-Anne; Dodet, B; Lambert, Paul Henri 1998
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Determinants of infant responses to vaccines in presence of maternal antibodies Siegrist, Claire-Anne; Cordova Mesa, Marco; Brandt-Schaichet, Catheine; Barrios-Janko, Christy; ... Lambert, Paul Henri 1998
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New challenges for global immunization Lambert, Paul Henri; Siegrist, Claire-Anne 1998
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