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AEB071 (sotrastaurin) does not exhibit toxic effects on human islets in vitro, nor after transplantation into immunodeficient mice Merani, Shaheed; McCall, Michael; Pawlick, Rena L; Edgar, Ryan L; ... Shapiro, A M James 2011
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Detecting rejection after mouse Islet transplantation utilizing islet protein-stimulated ELISPOT. Toso, Christian; Pawlick, Rena; Lacotte, Stéphanie; Edgar, Ryan; ... Shapiro, A M James 2011
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The caspase inhibitor IDN-6556 (PF3491390) improves marginal mass engraftment after islet transplantation in mice McCall, Michael; Toso, Christian; Emamaullee, Juliet; Pawlick, Rena; ... Shapiro, A M James 2011
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Liraglutide, a long-acting human glucagon-like peptide 1 analogue, improves human islet survival in culture Toso, Christian; McCall, Michael; Emamaullee, Juliet; Merani, Shaheed; ... Shapiro, A M James 2010
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Caspase inhibitor therapy synergizes with costimulation blockade to promote indefinite islet allograft survival Emamaullee, Juliet A.; Davis, Joy; Pawlick, Rena; Toso, Christian; ... Shapiro, A M James 2010
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Porcine marginal mass islet autografts resist metabolic failure over time and are enhanced by early treatment with liraglutide Emamaullee, Juliet A.; Merani, Shaheed; Toso, Christian; Kin, Tatsuya; ... Shapiro, A M James 2009
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Inhibition of Th17 cells regulates autoimmune diabetes in NOD mice Emamaullee, Juliet A.; Davis, Joy; Merani, Shaheed; Toso, Christian; ... Shapiro, A M James 2009
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The caspase selective inhibitor EP1013 augments human islet graft function and longevity in marginal mass islet transplantation in mice Emamaullee, Juliet A.; Davis, Joy; Pawlick, Rena; Toso, Christian; ... Shapiro, A M James 2008