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Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points-Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC) International Clopidogrel Pharmacogenomics Consortium 2018
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Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder Reinbold, Céline S; Forstner, Andreas J; Hecker, Julian; Fullerton, Janice M; ... Cichon, Sven 2018
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Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI Gong, J; Nishimura, K K; Fernandez-Rhodes, L; Haessler, J; ... Peters, U 2018
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A comprehensive evaluation of the genetic architecture of sudden cardiac arrest SCD working group of the CHARGE Consortium 2018
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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits Evangelou, Evangelos; Warren, Helen R; Mosen-Ansorena, David; Mifsud, Borbala; ... Caulfield, Mark J 2018
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PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity van Setten, Jessica; Brody, Jennifer A; Jamshidi, Yalda; Swenson, Brenton R; ... Sotoodehnia, Nona 2018
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Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries Collaboration 2018
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A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure Sung, Yun J.; Winkler, Thomas W.; de las Fuentes, Lisa; Bentley, Amy R.; ... Chasman, Daniel I. 2018
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Maternal eating disorders affect offspring cord blood DNA methylation: a prospective study Kazmi, Nabila; Gaunt, Tom R; Relton, Caroline; Micali, Nadia 2017
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Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa Duncan, Laramie; Yilmaz, Zeynep; Gaspar, Helena; Walters, Raymond; ... Bulik, Cynthia M 2017
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Molecular pathways associated with blood pressure and hexadecanedioate levels Menni, Cristina; Metrustry, Sarah J; Ehret, Georg Benedikt; Dominiczak, Anna F; ... Valdes, Ana M 2017
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Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations Yoneyama, S; Yao, J; Guo, X; Fernandez-Rhodes, L; ... North, K E 2017
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Genetic loci associated with heart rate variability and their effects on cardiac disease risk Nolte, Ilja M; Munoz, M Loretto; Tragante, Vinicius; Snieder, Harold; de Geus, Eco J C 2017
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New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals CHARGE EXOME BP Consortium, CHD Exome+ Consortium, Exome BP Consortium, GoT2D:T2DGenes Consortium, The UK Biobank Cardio-Metabolic Traits Consortium Blood Pressure Working Group 2017
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Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation Hoffmann, Thomas J; Ehret, Georg Benedikt; Nandakumar, Priyanka; Ranatunga, Dilrini; ... Risch, Neil 2017
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Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study Hou, Liping; Heilbronner, Urs; Degenhardt, Franziska; Kelsoe, John R; ... Schulze, Thomas G 2016
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Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior Cornelis, Marilyn C; Kacprowski, Tim; Menni, Cristina; Gustafsson, Stefan; ... Ingelsson, E 2016
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The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals Ehret, Georg Benedikt; Ferreira, Teresa; Morris, Andrew P; Newton-Cheh, Christopher; Munroe, Patricia B 2016
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Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci Liu, Chunyu; Kraja, Aldi T; Smith, Jennifer A; Brody, Jennifer A; ... Chasman, Daniel I 2016
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An integrated genomic-transcriptomic approach supports a role for the proto-oncogene BCL3 in atherosclerosis Marchetti, Giovanna; Girelli, Domenico; Zerbinati, Carlotta; Lunghi, Barbara; ... Martinelli, Nicola 2015
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Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans GTEx Consortium 2015
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Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors van de Bunt, Martijn; Manning Fox, Jocelyn E; Dai, Xiaoqing; Barrett, Amy; ... Gloyn, Anna L 2015
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Post-Transcriptional Regulation of Renalase Gene by miR-29 and miR-146 MicroRNAs: Implications for Cardiometabolic Disorders Kalyani, Ananthamohan; Sonawane, Parshuram J; Khan, Abrar Ali; Subramanian, Lakshmi; ... Mahapatra, Nitish R 2015
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The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study Winkler, Thomas W; Justice, Anne E; Graff, Mariaelisa; Barata, Llilda 2015
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Genetic studies of body mass index yield new insights for obesity biology Locke, Adam E; Kahali, Bratati; Berndt, Sonja I; Justice, Anne E; ... Mach, François 2015
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Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation Tsaprouni, Loukia G; Yang, Tsun-Po; Bell, Jordana; Dick, Katherine J; ... Deloukas, Panos 2014
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High risk population isolate reveals low frequency variants predisposing to intracranial aneurysms Kurki, Mitja I; Gaál, Emília Ilona; Kettunen, Johannes; Lappalainen, Tuuli Emilia; ... Jääskeläinen, Juha E 2014
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Putative cis-regulatory drivers in colorectal cancer Ongen, Halit; Andersen, Claus L; Bramsen, Jesper B; Oster, Bodil; ... Dermitzakis, Emmanouil 2014
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Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants Pasquali, Lorenzo; Gaulton, Kyle J; Rodríguez-Seguí, Santiago A; Mularoni, Loris; ... Ferrer, Jorge 2014
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SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease Ramirez, Alfredo; van der Flier, Wiesje M; Herold, Christine; Ramonet, David 2014
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Predicting stroke through genetic risk functions: the CHARGE Risk Score Project Ehret, Georg Benedikt 2014
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Genetic implication of a novel thiamine transporter in human hypertension International Consortium for Blood Pressure Genome-Wide Association Studies 2014
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Exome sequencing identifies putative drivers of progression of transient myeloproliferative disorder to AMKL in infants with Down syndrome Nikolaev, Sergey Igorievich; Santoni, Federico; Vannier, Anne; Falconnet, Emilie; ... Antonarakis, Stylianos 2013
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A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease Holmans, Peter; Moskvina, Valentina; Jones, Lesley; Sharma, Manu; ... Morris, Huw R 2013
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Gene expression changes with age in skin, adipose tissue, blood and brain Glass, Daniel; Viñuela, Ana; Davies, Matthew N; Ramasamy, Adaikalavan; ... Spector, Tim D 2013
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Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls Brenner, Darren R; Brennan, Paul; Boffetta, Paolo; Amos, Christopher I; ... Hung, Rayjean J 2013
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Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations O'Seaghdha, Conall M; Guessous, Idris; Köttgen, Anna; Wallaschofski, Henri; ... Bochud, Murielle 2013
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A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A. Lane, Jérôme; Boehlen, Françoise 2013
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A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study Peters, Ulrike; North, Kari E; Sethupathy, Praveen; Buyske, Steve; ... Kooperberg, Charles 2013
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Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations Franceschini, Nora 2013
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Discovery and refinement of loci associated with lipid levels Global Lipids Genetics Consortium 2013
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Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression Trudu, Matteo; Janas, Sylvie; Lanzani, Chiara; Debaix, Huguette; ... Rampoldi, Luca 2013
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Loci influencing blood pressure identified using a cardiovascular gene-centric array Ganesh, Santhi K; Tragante, Vinicius; Guo, Wei 2013
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Extensive natural variation for cellular hydrogen peroxide release is genetically controlled Attar Cohen, Homa; Bedard, Karen; Migliavacca Voeffray, Eugenia Linda; Gagnebin, Maryline; ... Antonarakis, Stylianos 2012
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Extent, causes, and consequences of small RNA expression variation in human adipose tissue Parts, Leopold; Hedman, Åsa K; Keildson, Sarah; Knights, Andrew J; ... Lindgren, Cecilia M 2012
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The Brisbane Systems Genetics Study: genetical genomics meets complex trait genetics Powell, Joseph E; Henders, Anjali K; McRae, Allan F; Caracella, Anthony; ... Montgomery, Grant W 2012
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Analysis of case-control association studies with known risk variants Zaitlen, Noah; Pasaniuc, Bogdan; Patterson, Nick; Pollack, Samuela; ... Price, Alkes L 2012
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Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population Bell, Jordana T; Tsai, Pei-Chien; Yang, Tsun-Po; Pidsley, Ruth; ... Deloukas, Panos 2012
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Genetic control of gene expression in whole blood and lymphoblastoid cell lines is largely independent Powell, Joseph E; Henders, Anjali K; McRae, Allan F; Wright, Margaret J; ... Visscher, Peter M 2012
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An integrated encyclopedia of DNA elements in the human genome ENCODE Project Consortium 2012
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