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The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity Echeverria, Pablo Christian; Bhattacharya, Kaushik; Joshi, Abhinav; Wang, Tai; Picard, Didier 2019
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Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling Segala, Grégory; Bennesch, Marcela; Mohammadi Ghahhari, Nastaran; Pandey, Deo Prakash; ... Picard, Didier 2019
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AF291 and AE391 single-chain antibodies recognize the HA tag by Western blotting Keszei, Zsofia; Picard, Didier 2019
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AI179 single-chain antibody recognizes the Myc tag by Western blotting Keszei, Zsofia; Picard, Didier 2019
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A scoring approach for multi-platform acquisition in metabolomics Pezzatti, Julian; Gonzalez Ruiz, Victor; Codesido Sanchez, Santiago; Gagnebin, Yoric; ... Rudaz, Serge 2019
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Luminescence resonance energy transfer between genetically encoded donor and acceptor for protein-protein interaction studies in the molecular chaperone HSP70/HSP90 complexes Bhattacharya, Kaushik; Bernasconi, Lilia; Picard, Didier 2018
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ERα activity depends on interaction and target site corecruitment with phosphorylated CREB1 Berto, Mélissa; Jean, Valérie; Zwart, Wilbert; Picard, Didier 2018
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Methods to validate Hsp90 inhibitor specificity, to identify off-target effects, and to rethink approaches for further clinical development Neckers, Len; Blagg, Brian; Haystead, Timothy; Trepel, Jane B.; ... Picard, Didier 2018
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Defective glucocorticoid receptor signaling and keratinocyte-autonomous defects contribute to skin phenotype of mouse embryos lacking the Hsp90 co-chaperone p23 Madon-Simon, Marta; Grad, Iwona; Bayo, Pilar; Pérez, Paloma; Picard, Didier 2017
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Cytosolic Hsp90α and its mitochondrial isoform Trap1 are differentially required in a breast cancer model Vartholomaiou, Evangelia; Madon-Simon, Marta; Hagmann, Stéphane; Muhlebach, Guillaume; ... Picard, Didier 2017
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Dendrogenin A drives LXR to trigger lethal autophagy in cancers Segala, Grégory; David, Marion; de Medina, Philippe; Poirot, Mathias C.; ... Silvente-Poirot, Sandrine 2017
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Secreted dual reporter assay with Gaussia luciferase and the red fluorescent protein mCherry Wider, Diana; Picard, Didier 2017
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Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson’s disease Fitzgerald, Julia C.; Zimprich, Alexander; Carvajal Berrio, Daniel A.; Schindler, Kevin M.; ... Krüger, Rejko 2017
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H2B monoubiquitination: t'ub or not t'ub for inducible enhancers Segala, Grégory; Picard, Didier 2017
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Long-Lasting and Fast-Acting in Vivo Efficacious Antiplasmodial Azepanylcarbazole Amino Alcohol Abla, Nada; Bashyam, Sridevi; Charman, Susan A.; Greco, Béatrice; ... Spangenberg, Thomas 2017
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A genetic polymorphism repurposes the G-protein coupled and membrane-associated estrogen receptor GPER to a transcription factor-like molecule promoting paracrine signaling between stroma and breast carcinoma cells Pupo, Marco; Bodmer, Alexandre; Berto, Mélissa; Maggiolini, Marcello; ... Picard, Didier 2017
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LSD1 engages a corepressor complex for the activation of the estrogen receptor α by estrogen and cAMP Bennesch, Marcela; Segala, Grégory; Wider, Diana; Picard, Didier 2016
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Monoubiquitination of Histone H2B Blocks Eviction of Histone Variant H2A.Z from Inducible Enhancers Segala, Grégory; Bennesch, Marcela; Pandey, Deo Prakash; Hulo, Nicolas; Picard, Didier 2016
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GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response De Marco, Paola; Lappano, Rosamaria; Francesco, Ernestina Marianna De; Cirillo, Francesca; ... Maggiolini, Marcello 2016
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Unusual Suspects in the Twilight Zone Between the Hsp90 Interactome and Carcinogenesis Vartholomaiou, Evangelia; Echeverria, Pablo Christian; Picard, Didier 2016
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A remodeled Hsp90 molecular chaperone ensemble with the novel co-chaperone Aarsd1 is required for muscle differentiation Echeverria, Pablo Christian; Briand, Pierre André; Picard, Didier 2016
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Inhibition of Plasmodium falciparum Hsp90 Contributes to the Antimalarial Activities of Aminoalcohol-carbazoles Wang, Tai; Mäser, Pascal; Picard, Didier 2016
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Minireview: Tipping the balance: ligand-independent activation of steroid receptors Bennesch, Marcela; Picard, Didier 2015
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Differences in Conformational Dynamics between Plasmodium falciparum and Human Hsp90 Orthologues Enable the Structure-Based Discovery of Pathogen-Selective Inhibitors Wang, Tai; Bisson, William Henry; Mäser, Pascal; Scapozza, Leonardo; Picard, Didier 2014
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Mitochondrial oxidative phosphorylation TRAP(1)ped in tumor cells Rasola, Andrea; Neckers, Len; Picard, Didier 2014
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A global view of the proteome perturbations by Hsp90 inhibitors Echeverria, Pablo Christian; Picard, Didier 2014
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Overview of molecular chaperones in health and disease Wang, Tai; Echeverria, Pablo Christian; Picard, Didier 2014
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Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis Yoshida, Soichiro; Tsutsumi, Shinji; Muhlebach, Guillaume; Sourbier, Carole; ... Neckers, Leonard 2013
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The Human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter Hasan, Uzma A.; Zannetti, Claudia; Parroche, Peggy; Goutagny, Nadège; ... Tommasino, Massimo 2013
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Dynamic Impacts of the Inhibition of the Molecular Chaperone Hsp90 on the T-Cell Proteome Have Implications for Anti-Cancer Therapy Fierro-Monti, Ivo; Echeverria, Pablo Christian; Racle, Julien; Hernandez, Celine; ... Quadroni, Manfredo 2013
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Preface to Hsp90 Picard, Didier 2012
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The Cholesterol Metabolite 25-Hydroxycholesterol Activates Estrogen Receptor α-Mediated Signaling in Cancer Cells and in Cardiomyocytes Lappano, Rosamaria; Recchia, Anna Grazia; De Francesco, Ernestina Marianna; Angelone, Tommaso; ... Maggiolini, Marcello 2011
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Detection of changes in gene regulatory patterns, elicited by perturbations of the Hsp90 molecular chaperone complex, by visualizing multiple experiments with an animation Echeverria, Pablo Christian; Forafonov, Fedor; Pandey, Deo Prakash; Muhlebach, Guillaume; Picard, Didier 2011
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Influenza Virus Infection Induces the Nuclear Relocalization of the Hsp90 Co-Chaperone p23 and Inhibits the Glucocorticoid Receptor Response Ge, Xingyi; Rameix-Welti, Marie-Anne; Gault, Elyanne; Chase, Geoffrey; ... Naffakh, Nadia 2011
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An Interaction Network Predicted from Public Data as a Discovery Tool: Application to the Hsp90 Molecular Chaperone Machine Echeverria, Pablo Christian; Bernthaler, Andreas; Dupuis, Pierre Marcel Jean; Mayer, Bernd; Picard, Didier 2011
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CARM1 mediates the ligand-independent and tamoxifen-resistant activation of the estrogen receptor alpha by cAMP Carascossa, Sophie; Dudek, Peter; Cenni, Bruno; Briand, Pierre-André; Picard, Didier 2010
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Multidirectional interplay between nuclear receptors and microRNAs Pandey, Deo Prakash; Picard, Didier 2010
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Molecular chaperones, essential partners of steroid hormone receptors for activity and mobility Echeverria, Pablo Christian; Picard, Didier 2010
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The molecular chaperone Hsp90alpha is required for meiotic progression of spermatocytes beyond pachytene in the mouse Grad, Iwona; Cederroth, Christopher; Walicki, Joël Jonathan; Grey, Corinne; ... Picard, Didier 2010
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The unfolding stories of GPR30, a new membrane-bound estrogen receptor Maggiolini, Marcello; Picard, Didier 2010
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Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF Pandey, Deo Prakash; Lappano, Rosamaria; Albanito, Lidia; Madeo, Antonio; ... Picard, Didier 2009
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The complementation of yeast with human or Plasmodium falciparum Hsp90 confers differential inhibitor sensitivities Wider, Diana; Péli-Gulli, Marie-Pierre; Briand, Pierre-André; Tatu, Utpal; Picard, Didier 2009
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miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA Pandey, Deo Prakash; Picard, Didier 2009
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A stress protein interface of innate immunity Picard, Didier 2008
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Genomics of signaling crosstalk of estrogen receptor alpha in breast cancer cells Dudek, Peter; Picard, Didier 2008
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p23/Sba1p protects against Hsp90 inhibitors independently of its intrinsic chaperone activity Forafonov, Fedor; Toogun, Oyetunji A.; Grad, Iwona; Suslova, Elena; ... Picard, Didier 2008
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Epidermal growth factor induces G protein-coupled receptor 30 expression in estrogen receptor-negative breast cancer cells Albanito, Lidia; Sisci, Diego; Aquila, Saveria; Brunelliere, Angèle; ... Maggiolini, Marcello 2008
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The exception that reinforces the rule: crosspriming by cytosolic peptides that escape degradation Lev, Avital; Takeda, Kazuyo; Zanker, Damien; Maynard, Jason C.; ... Yewdell, Jonathan W. 2008
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The glucocorticoid responses are shaped by molecular chaperones Grad, Iwona; Picard, Didier 2007
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Molecular and clinical characteristics in 46 families affected with Peutz-Jeghers syndrome Mehenni, Hamid; Resta, Nicoletta; Guanti, Ginevra; Mota-Vieira, Louisa; ... Picard, Didier 2007
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