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Environmental and T cell-intrinsic factors limit the expansion of neonatal follicular T helper cells but may be circumvented by specific adjuvants Mastelic-Gavillet, Beatris; Kamath, Arun; Fontannaz, Paola; Tougne, Chantal; ... Siegrist, Claire-Anne 2012
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Vaccine effectiveness in older individuals: what has been learned from the influenza-vaccine experience Lang, Pierre-Olivier; Govind, Sheila; Mitchell, Wayne A; Siegrist, Claire-Anne; Aspinall, Richard 2011
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Early life T cell responses to pneumococcal conjugates increase with age and determine the polysaccharide-specific antibody response and protective efficacy Jakobsen, Håvard; Hannesdottir, Solveig; Bjarnarson, Stefania P; Schulz, Dominique; ... Jonsdottir, Ingileif 2006
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Hepatitis B immunisation induces higher antibody and memory Th2 responses in new-borns than in adults Ota, Martin OC; Vekemans, Johan; Schlegel Heueter, Susanna; Fielding, Katherine; ... Marchant, Arnaud 2004
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Unresponsiveness to lymphoid-mediated signals at the neonatal follicular dendritic cell precursor level contributes to delayed germinal center induction and limitations of neonatal antibody responses to T-dependent antigens Pihlgren Bosch, Maria Astrid Louise; Tougne, Chantal; Bozzotti, Paola; Fulurija, Alma; ... Siegrist, Claire-Anne 2003
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CpG-motifs enhance initial and sustained primary tetanus-specific antibody secreting cell responses in spleen and bone marrow, but are more effective in adult than in neonatal mice Pihlgren Bosch, Maria Astrid Louise; Tougne, Chantal; Schallert, Nadine; Bozzotti, Paola; ... Siegrist, Claire-Anne 2003
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Generation of adult-like antibody avidity profiles after early-life immunization with protein vaccines Schallert, Nadine; Pihlgren Bosch, Maria Astrid Louise; Kovarik, Jiri; Roduit, Caroline Monique; ... Lambert, Paul Henri 2002
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Adjuvant effects of CpG oligodeoxynucleotides on responses against T-independent type 2 antigens Kovarik, Jiri; Bozzotti, P; Tougne, Chantal; Davis, HL; ... Siegrist, Claire-Anne 2001
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Age-associated decline in cdk1 activity delays cell cycle progression of human T lymphocytes Quadri Defilippis, Rafael; Arbogast, Agnès; Phelouzat Taramarcaz, Marie-Anne; Boutet, S; ... Proust, Jacques 1998
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CpG DNA can induce strong Th1 humoral and cell-mediated immune responses against hepatitis B surface antigen in young mice Brazolot Millan, C L; Weeratna, R; Krieg, A M; Siegrist, Claire-Anne; Davis, H L 1998