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Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points-Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC) International Clopidogrel Pharmacogenomics Consortium 2018
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Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder Reinbold, Céline S; Forstner, Andreas J; Hecker, Julian; Fullerton, Janice M; ... Cichon, Sven 2018
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Maternal eating disorders affect offspring cord blood DNA methylation: a prospective study Kazmi, Nabila; Gaunt, Tom R; Relton, Caroline; Micali, Nadia 2017
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Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa Duncan, Laramie; Yilmaz, Zeynep; Gaspar, Helena; Walters, Raymond; ... Bulik, Cynthia M 2017
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Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study Hou, Liping; Heilbronner, Urs; Degenhardt, Franziska; Kelsoe, John R; ... Schulze, Thomas G 2016
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Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior Cornelis, Marilyn C; Kacprowski, Tim; Menni, Cristina; Gustafsson, Stefan; ... Ingelsson, E 2016
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An integrated genomic-transcriptomic approach supports a role for the proto-oncogene BCL3 in atherosclerosis Marchetti, Giovanna; Girelli, Domenico; Zerbinati, Carlotta; Lunghi, Barbara; ... Martinelli, Nicola 2015
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Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans GTEx Consortium 2015
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Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors van de Bunt, Martijn; Manning Fox, Jocelyn E; Dai, Xiaoqing; Barrett, Amy; ... Gloyn, Anna L 2015
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Post-Transcriptional Regulation of Renalase Gene by miR-29 and miR-146 MicroRNAs: Implications for Cardiometabolic Disorders Kalyani, Ananthamohan; Sonawane, Parshuram J; Khan, Abrar Ali; Subramanian, Lakshmi; ... Mahapatra, Nitish R 2015
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The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study Winkler, Thomas W; Justice, Anne E; Graff, Mariaelisa; Barata, Llilda 2015
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Genetic studies of body mass index yield new insights for obesity biology Locke, Adam E; Kahali, Bratati; Berndt, Sonja I; Justice, Anne E; ... Mach, François 2015
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Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation Tsaprouni, Loukia G; Yang, Tsun-Po; Bell, Jordana; Dick, Katherine J; ... Deloukas, Panos 2014
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High risk population isolate reveals low frequency variants predisposing to intracranial aneurysms Kurki, Mitja I; Gaál, Emília Ilona; Kettunen, Johannes; Lappalainen, Tuuli Emilia; ... Jääskeläinen, Juha E 2014
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Putative cis-regulatory drivers in colorectal cancer Ongen, Halit; Andersen, Claus L; Bramsen, Jesper B; Oster, Bodil; ... Dermitzakis, Emmanouil 2014
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Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants Pasquali, Lorenzo; Gaulton, Kyle J; Rodríguez-Seguí, Santiago A; Mularoni, Loris; ... Ferrer, Jorge 2014
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SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease Ramirez, Alfredo; van der Flier, Wiesje M; Herold, Christine; Ramonet, David 2014
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Predicting stroke through genetic risk functions: the CHARGE Risk Score Project Ehret, Georg Benedikt 2014
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Genetic implication of a novel thiamine transporter in human hypertension International Consortium for Blood Pressure Genome-Wide Association Studies 2014
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Exome sequencing identifies putative drivers of progression of transient myeloproliferative disorder to AMKL in infants with Down syndrome Nikolaev, Sergey Igorievich; Santoni, Federico; Vannier, Anne; Falconnet, Emilie; ... Antonarakis, Stylianos 2013
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A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease Holmans, Peter; Moskvina, Valentina; Jones, Lesley; Sharma, Manu; ... Morris, Huw R 2013
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Gene expression changes with age in skin, adipose tissue, blood and brain Glass, Daniel; Viñuela, Ana; Davies, Matthew N; Ramasamy, Adaikalavan; ... Spector, Tim D 2013
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Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls Brenner, Darren R; Brennan, Paul; Boffetta, Paolo; Amos, Christopher I; ... Hung, Rayjean J 2013
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Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations O'Seaghdha, Conall M; Guessous, Idris; Köttgen, Anna; Wallaschofski, Henri; ... Bochud, Murielle 2013
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A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A. Lane, Jérôme; Boehlen, Françoise 2013
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A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study Peters, Ulrike; North, Kari E; Sethupathy, Praveen; Buyske, Steve; ... Kooperberg, Charles 2013
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Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations Franceschini, Nora 2013
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Discovery and refinement of loci associated with lipid levels Global Lipids Genetics Consortium 2013
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Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression Trudu, Matteo; Janas, Sylvie; Lanzani, Chiara; Debaix, Huguette; ... Rampoldi, Luca 2013
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Loci influencing blood pressure identified using a cardiovascular gene-centric array Ganesh, Santhi K; Tragante, Vinicius; Guo, Wei 2013
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Extensive natural variation for cellular hydrogen peroxide release is genetically controlled Attar Cohen, Homa; Bedard, Karen; Migliavacca Voeffray, Eugenia Linda; Gagnebin, Maryline; ... Antonarakis, Stylianos 2012
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Extent, causes, and consequences of small RNA expression variation in human adipose tissue Parts, Leopold; Hedman, Åsa K; Keildson, Sarah; Knights, Andrew J; ... Lindgren, Cecilia M 2012
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The Brisbane Systems Genetics Study: genetical genomics meets complex trait genetics Powell, Joseph E; Henders, Anjali K; McRae, Allan F; Caracella, Anthony; ... Montgomery, Grant W 2012
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Analysis of case-control association studies with known risk variants Zaitlen, Noah; Pasaniuc, Bogdan; Patterson, Nick; Pollack, Samuela; ... Price, Alkes L 2012
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Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population Bell, Jordana T; Tsai, Pei-Chien; Yang, Tsun-Po; Pidsley, Ruth; ... Deloukas, Panos 2012
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Genetic control of gene expression in whole blood and lymphoblastoid cell lines is largely independent Powell, Joseph E; Henders, Anjali K; McRae, Allan F; Wright, Margaret J; ... Visscher, Peter M 2012
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An integrated encyclopedia of DNA elements in the human genome ENCODE Project Consortium 2012
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Genome-wide linkage and copy number variation analysis reveals 710 kb duplication on chromosome 1p31.3 responsible for autosomal dominant omphalocele Radhakrishna, Uppala; Nath, Swapan K; McElreavey, Ken; Ratnamala, Uppala; ... Butler, Merlin G 2012
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Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis Paternoster, Lavinia; Standl, Marie 2012
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An integrated map of genetic variation from 1,092 human genomes 1000 Genomes Project Consortium 2012
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Large-scale replication and heterogeneity in Parkinson disease genetic loci Sharma, Manu 2012
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Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysis Tansey, Katherine E; Guipponi, Michel; Perroud, Nader Ali; Bondolfi, Guido; ... Uher, Rudolf 2012
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A multi-SNP locus-association method reveals a substantial fraction of the missing heritability Ehret, Georg Benedikt; Lamparter, David; Hoggart, Clive J.; Whittaker, John C.; ... Kutalik, Zoltán 2012
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Genome-wide profiling of blood pressure in adults and children Taal, Hendrik R; Verwoert, Germaine C; Demirkan, Ayse; Janssens, A Cecile J W; ... van Duijn, Cornelia 2012
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Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection Patin, Etienne; Kutalik, Zoltán; Guergnon, Julien; Bibert, Stéphanie; ... Abel, Laurent 2012
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Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes Small, Kerrin S; Hedman, Asa K; Grundberg, Elin; Nica, Alexandra; ... Dermitzakis, Emmanouil 2011
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From expression QTLs to personalized transcriptomics Montgomery, Stephen; Dermitzakis, Emmanouil 2011
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Identification of cis- and trans-regulatory variation modulating microRNA expression levels in human fibroblasts Borel, Christelle; Deutsch Escalante, Samuel; Letourneau, Audrey; Migliavacca Voeffray, Eugenia Linda; ... Antonarakis, Stylianos 2011
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Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population Saad, Mohamad; Lesage, Suzanne; Saint-Pierre, Aude; Corvol, Jean-Christophe; ... Brice, Alexis 2011
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Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus Jacquemont, Sébastien 2011
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