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MHC class II molecules enhance Toll-like receptor mediated innate immune responses Frei, Remo; Steinle, Johanna; Birchler, Thomas; Loeliger, Susanne; ... Lauener, R. P. 2010
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Transcriptional regulation of matrix metalloproteinase-1 and collagen 1A2 explains the anti-fibrotic effect exerted by proteasome inhibition in human dermal fibroblasts Goffin, Laurence; Seguin-Estevez, Queralt; Alvarez, Montserrat; Reith, Walter; Chizzolini, Carlo 2010
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MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity Irla, Magali; Kupfer, Natalia; Suter, Tobias; Lissilaa, Rami; ... Hugues, Stéphanie 2010
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RFX3 governs growth and beating efficiency of motile cilia in mouse and controls the expression of genes involved in human ciliopathies El Zein, Loubna; Ait-Lounis, Aouatef; Morlé, Laurette; Thomas, Joëlle; ... Durand, Bénédicte 2009
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Nucleosome eviction from MHC class II promoters controls positioning of the transcription start site Leimgruber, Elisa; Seguin-Estevez, Queralt; Dunand-Sauthier, Isabelle; Rybtsova, Natalia; ... Reith, Walter 2009
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MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells Ceppi, Maurizio; Pereira, P. M.; Dunand-Sauthier, Isabelle; Barras, Emmanuele; ... Pierre, Philippe 2009
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The transcription factor RFX protects MHC class II genes against epigenetic silencing by DNA methylation Seguin-Estevez, Queralt; De Palma, Raffaele; Krawczyk, Michal; Leimgruber, Elisa; ... Reith, Walter 2009
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Pancreatic inactivation of c-Myc decreases acinar mass and transdifferentiates acinar cells into adipocytes in mice Bonal, Claire; Thorel, Fabrizio; Ait-Lounis, Aouatef; Reith, Walter; ... Herrera, Pedro Luis 2009
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Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis Carobbio, Stefania; Frigerio, Francesca; Rubi, Blanca; Vetterli, Laurene; ... Maechler, Pierre 2009
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The NLR gene family: a standard nomenclature Ting, Jenny P.-Y.; Lovering, Ruth C.; Alnemri, Emad S.; Bertin, John; ... Ward, Peter A. 2008
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New dimensions of CIITA Reith, Walter; Boss, Jeremy M. 2008
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Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity Irla, Magali; Hugues, Stéphanie; Gill, Jason; Nitta, Takeshi; ... Reith, Walter 2008
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Identification of CIITA regulated genetic module dedicated for antigen presentation Krawczyk, Michal; Seguin Estévez, Maria Queralt; Leimgruber, Elisa; Sperisen, Peter; ... Reith, Walter 2008
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Expression of RAB4B, a protein governing endocytic recycling, is co-regulated with MHC class II genes Krawczyk, Michal; Leimgruber, Elisa; Seguin-Estevez, Queralt; Dunand-Sauthier, Isabelle; ... Reith, Walter 2007
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Transcription-coupled deposition of histone modifications during MHC class II gene activation Rybtsova, Natalia; Leimgruber, Elisa; Seguin-Estevez, Queralt; Dunand-Sauthier, Isabelle; ... Reith, Walter 2007
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Novel function of the ciliogenic transcription factor RFX3 in development of the endocrine pancreas Ait-Lounis, Aouatef; Baas, Dominique; Barras, Emmanuele; Benadiba, Carine; ... Reith, Walter 2007
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The assembly and maintenance of heterochromatin initiated by transgene repeats are independent of the RNA interference pathway in mammalian cells Wang, Fangwei; Koyama, Naoki; Nishida, Hiroko; Haraguchi, Tokuko; ... Tsukamoto, Toshiro 2006
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Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts Fineschi, Serena; Reith, Walter; Guerne, P. A.; Dayer, Jean-Michel; Chizzolini, Carlo 2006
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TGFbeta receptor II gene deletion in leucocytes prevents cerebral vasculitis in bacterial meningitis Malipiero, Ursula; Koedel, Uwe; Pfister, H. W.; Leveen, Per; ... Fontana, Adriano 2006
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Functional CD8+ but not CD4+ T cell responses develop independent of thymic epithelial MHC Martinic, M. M.; van den Broek, M. F.; Rulicke, Thomas; Huber, Christoph; ... Zinkernagel, R. M. 2006
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Revisiting the specificity of the MHC class II transactivator CIITA in vivo Otten, L. A.; Leibundgut-Landmann, Salomé; Huarte, Joachim; Kos-Braun, I. C.; ... Reith, Walter 2006
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Circulating, soluble forms of major histocompatability complex antigens are not exosome-associated MacKay, P. A.; Leibundgut-Landmann, Salomé; Koch, Norbert; Dunn, A. C.; ... McLellan, A. D. 2006
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Regulation of MHC class II expression, a unique regulatory system identified by the study of a primary immunodeficiency disease Krawczyk, Michal; Reith, Walter 2006
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A deficiency in RFX3 causes hydrocephalus associated with abnormal differentiation of ependymal cells Baas, Dominique; Meiniel, A.; Benadiba, Carine; Bonnafe, E.; ... Durand, Bénédicte 2006
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New functions of the major histocompatibility complex class II-specific transcription factor RFXANK revealed by a high-resolution mutagenesis study Krawczyk, Michal; Masternak, Krzysztof; Zufferey, Madeleine; Barras, Emmanuele; Reith, Walter 2005
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Regulation of MHC class II gene expression by the class II transactivator Reith, Walter; Leibundgut-Landmann, Salomé; Waldburger, Jean-Marc 2005
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Long distance control of MHC class II expression by multiple distal enhancers regulated by regulatory factor X complex and CIITA Krawczyk, Michal; Peyraud, Nicolas; Rybtsova, Natalia; Masternak, Krzysztof; ... Reith, Walter 2004
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MHC class II expression is differentially regulated in plasmacytoid and conventional dendritic cells Leibundgut-Landmann, Salomé; Waldburger, Jean-Marc; Reis e Sousa, Caetano; Acha-Orbea, Hans; Reith, Walter 2004
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The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification Bonnafe, E.; Touka, M.; Ait-Lounis, Aouatef; Baas, Dominique; ... Reith, Walter 2004
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In vivo, RFX5 binds differently to the human leucocyte antigen-E, -F, and -G gene promoters and participates in HLA class I protein expression in a cell type-dependent manner Rousseau, Philippe; Masternak, Krzysztof; Krawczyk, Michal; Reith, Walter; ... Moreau, Philippe 2004
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The S box of major histocompatibility complex class II promoters is a key determinant for recruitment of the transcriptional co-activator CIITA Muhlethaler-Mottet, Annick; Krawczyk, Michal; Masternak, Krzysztof; Spilianakis, Charalambos; ... Reith, Walter 2004
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Mini-review: Specificity and expression of CIITA, the master regulator of MHC class II genes LeibundGut-Landmann, Salomé; Waldburger, Jean-Marc; Krawczyk, Michal; Otten, L. A.; ... Reith, Walter 2004
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Promoter IV of the class II transactivator gene is essential for positive selection of CD4+ T cells Waldburger, Jean-Marc; Rossi, Simona; Hollander, Georg; Rodewald, H. R.; ... Acha-Orbea, Hans 2003
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Deregulated MHC class II transactivator expression leads to a strong Th2 bias in CD4+ T lymphocytes Otten, L. A.; Tacchini-Cottier, Fabienne; Lohoff, Michael; Annunziato, Francesco; ... Acha-Orbea, Hans 2003
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ComPLEXIN new targets for CIITA Reith, Walter 2003
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Chromatin remodeling and extragenic transcription at the MHC class II locus control region Masternak, Krzysztof; Peyraud, Nicolas; Krawczyk, Michal; Barras, Emmanuele; Reith, Walter 2003
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RFX1 and NF-1 associate with P sequences of the human growth hormone locus in pituitary chromatin Norquay, L. D.; Yang, Xiaoyang; Sheppard, Patricia; Gregoire, Scott; ... Cattini, P. A. 2003
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The brain as an immune privileged site: dendritic cells of the central nervous system inhibit T cell activation Suter, Tobias; Biollaz, Gregoire; Gatto, Dominique; Bernasconi, Luca; ... Fontana, Adriano 2003
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TGFbeta directs gene expression of activated microglia to an anti-inflammatory phenotype strongly focusing on chemokine genes and cell migratory genes Paglinawan, Rey; Malipiero, Ursula; Schlapbach, Ralph; Frei, Karl; ... Fontana, Adriano 2003
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Promoter-specific functions of CIITA and the MHC class II enhanceosome in transcriptional activation Masternak, Krzysztof; Reith, Walter 2002
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Direct genetic correction as a new method for diagnosis and molecular characterization of MHC class II deficiency Matheux, Franck; Ikinciogullari, Aydan; Zapata, D. A.; Barras, Emmanuele; ... Villard, Jean 2002
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Selective abrogation of major histocompatibility complex class II expression on extrahematopoietic cells in mice lacking promoter IV of the class II transactivator gene Waldburger, Jean-Marc; Suter, T.; Fontana, Adriano; Acha-Orbea, Hans; Reith, Walter 2001
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Maturation of dendritic cells is accompanied by rapid transcriptional silencing of class II transactivator (CIITA) expression Landmann, S.; Muhlethaler-Mottet, Annick; Bernasconi, Luca; Suter, T.; ... Reith, Walter 2001
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Expression of the three human major histocompatibility complex class II isotypes exhibits a differential dependence on the transcription factor RFXAP Peretti, M.; Villard, Jean; Barras, Emmanuele; Zufferey, Madeleine; Reith, Walter 2001
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Primary immunodeficiency mutation databases Vihinen, M.; Arredondo-Vega, F. X.; Casanova, J. L.; Etzioni, A.; ... Smith, C. I. 2001
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The bare lymphocyte syndrome and the regulation of MHC expression Reith, Walter; Mach, Bernard 2001
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A functionally essential domain of RFX5 mediates activation of major histocompatibility complex class II promoters by promoting cooperative binding between RFX and NF-Y Villard, Jean; Peretti, M.; Masternak, Krzysztof; Barras, Emmanuele; ... Reith, Walter 2000
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Dissection of functional NF-Y-RFX cooperative interactions on the MHC class II Ea promoter Caretti, G.; Cocchiarella, F.; Sidoli, C.; Villard, Jean; ... Mantovani, R. 2000
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Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding Gajiwala, K. S.; Chen, H.; Cornille, F.; Roques, B. P.; ... Burley, S. K. 2000
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CIITA leucine-rich repeats control nuclear localization, in vivo recruitment to the major histocompatibility complex (MHC) class II enhanceosome, and MHC class II gene transactivation Hake, S. B.; Masternak, Krzysztof; Kammerbauer, C.; Janzen, C.; ... Steimle, Viktor 2000
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