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Oropharyngeal decontamination decreases incidence of ventilator-associated pneumonia. A randomized, placebo-controlled, double-blind clinical trial Pugin, Jérôme; Auckenthaler, Raymond; Lew, Daniel Pablo; Suter, Peter 1991
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CD14-dependent endotoxin internalization via a macropinocytic pathway Poussin, Carine Anne; Foti, Michelangelo; Carpentier, Jean-Louis; Pugin, Jérôme 1998
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The lectin-like domain of tumor necrosis factor-α increases membrane conductance in microvascular endothelial cells and peritoneal macrophages Hribar, Marusa; Bloc, Alain André Leon; Van Der Goot Grunberg, Françoise G.; Fransen, Lucie; ... Lucas, Rudolf 1999
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Membrane interaction of TNF is not sufficient to trigger increase in membrane conductance in mammalian cells Van Der Goot Grunberg, Françoise G.; Pugin, Jérôme; Hribar, Marusa; Fransen, Lucie; ... Lucas, Rudolf 1999
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Diagnostic value of procalcitonin, interleukin-6, and interleukin-8 in critically ill patients admitted with suspected sepsis Harbarth, Stéphan Juergen; Holeckova, K.; Froidevaux, C.; Pittet, Didier; ... Pugin, Jérôme 2001
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Inappropriate initial antimicrobial therapy and its effect on survival in a clinical trial of immunomodulating therapy for severe sepsis Harbarth, Stéphan Juergen; Garbino, Jorge; Pugin, Jérôme; Romand, Jacques-André; ... Pittet, Didier 2003
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Acute portal hemodynamics and cytokine changesfollowing selective transarterial chemoembolization in patients with cirrhosis and hepatocellular carcinoma Spahr, Laurent François Joséph; Becker, Christoph; Pugin, Jérôme; Majno, Pietro; Hadengue, Antoine 2003
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Role of Toll-like receptor 4 on pancreatic and pulmonary injury in a mice model of acute pancreatitis associated with endotoxemia Pastor, Catherine; Pugin, Jérôme; Kwak, Brenda; Chanson, Marc; ... Frossard, Jean-Louis 2004
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Utilité du dosage plasmatique de la procalcitonine chez l'adulte et chez l'enfant Gervaix, Alain; Pugin, Jérôme 2005
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Lack of effect of combination antibiotic therapy on mortality in patients with pneumococcal sepsis Harbarth, Stéphan Juergen; Garbino, Jorge; Pugin, Jérôme; Romand, Jacques-André; Pittet, Didier 2005
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Evaluation of rapid screening and pre-emptive contact isolation for detecting and controlling methicillin-resistant Staphylococcus aureus in critical care: an interventional cohort study Harbarth, Stéphan Juergen; Masuet-Aumatell, Cristina; Schrenzel, Jacques; Francois, Patrice; ... Pittet, Didier 2006
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Use of procalcitonin to shorten antibiotic treatment duration in septic patients: a randomized trial Nobre, Vandack; Harbarth, Stéphan Juergen; Graf, Jean-Daniel; Rohner, Peter; Pugin, Jérôme 2008
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Increased release of sMD-2 during human endotoxemia and sepsis: a role for endothelial cells Wolfs, Tim G.A.M.; Dunn-Siegrist, Irène; van't Veer, Cornelis; Hodin, Caroline M.I.M.; ... Buurman, Wim A. 2008
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Role of proinflammatory activity contained in gastric juice from intensive care unit patients to induce lung injury in a rabbit aspiration model Brégeon, Fabienne; Papazian, Laurent; Delpierre, Stéphane; Kajikawa, Osamu; ... Pugin, Jérôme 2008
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Year in review in Intensive Care Medicine, 2007. I. Experimental studies. Clinical studies: brain injury and neurology, renal failure and endocrinology Antonelli, Massimo; Azoulay, Elie; Bonten, Marc; Chastre, Jean; ... Zhang, Haibo 2008
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Year in review in Intensive Care Medicine, 2007. II. Haemodynamics, pneumonia, infections and sepsis, invasive and non-invasive mechanical ventilation, acute respiratory distress syndrome Antonelli, Massimo; Azoulay, Elie; Bonten, Marc; Chastre, Jean; ... Zhang, Haibo 2008
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Year in review in Intensive Care Medicine, 2007. III. Ethics and legislation, health services research, pharmacology and toxicology, nutrition and paediatrics Antonelli, Massimo; Azoulay, Elie; Bonten, Marc; Chastre, Jean; ... Zhang, Haibo 2008
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Pour un moratoire sur l'utilisation des hydroxyéthylamidons Brochard, Laurent; Schortgen, F.; Brun-Buisson, C.; Dreyfuss, D.; ... Richard, J.-C. M. 2008
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Cyclic stretch of human lung cells induces an acidification and promotes bacterial growth Pugin, Jérôme; Dunn-Siegrist, Irène; Dufour, Julien; Tissières, Pierre; ... Comte, Rachel 2008
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Dear SIRS, the concept of "alarmins" makes a lot of sense! Pugin, Jérôme 2008
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Profiling genes in the ICU: are we there yet? Pugin, Jérôme 2008
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Soluble MD-2 is an acute-phase protein and an opsonin for Gram-negative bacteria Tissières, Pierre; Dunn-Siegrist, Irène; Schaeppi, Michela; Elson, Greg; ... Pugin, Jérôme 2008
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Cooperation between PU.1 and CAAT/enhancer-binding protein beta is necessary to induce the expression of the MD-2 gene Tissières, Pierre; Araud, Tanguy; Ochoda, Agnieszka; Drifte Roduit, Geneviève Sophie; ... Pugin, Jérôme 2009
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The role of MD-2 in the opsonophagocytosis of Gram-negative bacteria Tissières, Pierre; Pugin, Jérôme 2009
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Year in review in Intensive Care Medicine, 2008: I. Brain injury and neurology, renal failure and endocrinology, metabolism and nutrition, sepsis, infections and pneumonia Antonelli, Massimo; Azoulay, Elie; Bonten, Marc; Chastre, Jean; ... Zhang, Haibo 2009
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Year in review in Intensive Care Medicine, 2008: II. Experimental, acute respiratory failure and ARDS, mechanical ventilation and endotracheal intubation Antonelli, Massimo; Azoulay, Elie; Bonten, Marc; Chastre, Jean; ... Zhang, Haibo 2009
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Year in review in Intensive Care Medicine, 2008: III. Paediatrics, ethics, outcome research and critical care organization, sedation, pharmacology and miscellanea Antonelli, Massimo; Azoulay, Elie; Bonten, Marc; Chastre, Jean; ... Zhang, Haibo 2009
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Long-term prognosis after acute kidney injury requiring renal replacement therapy Triverio, Pierre-Alain; Martin, Pierre-Yves; Romand, Jacques-André; Pugin, Jérôme; ... Saudan, Patrick 2009
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Year in review in Intensive Care Medicine 2010: I. Acute renal failure, outcome, risk assessment and ICU performance, sepsis, neuro intensive care and experimentals Antonelli, Massimo; Azoulay, Elie; Bonten, Marc; Chastre, Jean; ... Zhang, Haibo 2011
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Year in review in Intensive Care Medicine 2010: II. Pneumonia and infections, cardiovascular and haemodynamics, organization, education, haematology, nutrition, ethics and miscellanea Antonelli, Massimo; Azoulay, Elie; Bonten, Marc; Chastre, Jean; ... Zhang, Haibo 2011
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Mild-stretch mechanical ventilation upregulates toll-like receptor 2 and sensitizes the lung to bacterial lipopeptide Charles, Pierre-Emmanuel; Tissières, Pierre; Barbar, Saber Davide; Croisier, Delphine; ... Pugin, Jérôme 2011
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Severe leptospirosis with multiple organ failure successfully treated by plasma exchange and high-volume hemofiltration Bourquin, Vincent; Ponte, Belen; Hirschel, Bernard; Pugin, Jérôme; ... Saudan, Patrick 2011
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Toll-like receptor activation of human cells by synthetic triacylated lipid A-like molecules Dunn-Siegrist, Irène; Tissières, Pierre; Drifte Roduit, Geneviève Sophie; Bauer, Jacques; ... Pugin, Jérôme 2012
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The search for diagnostic markers in sepsis: many miles yet to go Calfee, Carolyn S; Pugin, Jérôme 2012
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How tissue injury alarms the immune system and causes a systemic inflammatory response syndrome Pugin, Jérôme 2012
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Innate immune deficiency of extremely premature neonates can be reversed by interferon-γ Tissières, Pierre; Ochoda, Agnieszka; Dunn-Siegrist, Irène; Drifte Roduit, Geneviève Sophie; ... Pugin, Jérôme 2012
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Epoetin administrated after cardiac surgery: effects on renal function and inflammation in a randomized controlled study De Seigneux Matthey, Sophie; Ponte, Belen; Weiss, Lucien; Pugin, Jérôme; ... Saudan, Patrick 2012
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Innate immune functions of immature neutrophils in patients with sepsis and severe systemic inflammatory response syndrome Drifte Roduit, Geneviève Sophie; Dunn-Siegrist, Irène; Tissières, Pierre; Pugin, Jérôme 2013
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Role of biomarkers in the management of antibiotic therapy: an expert panel review II: clinical use of biomarkers for initiation or discontinuation of antibiotic therapy Quenot, Jean-Pierre; Luyt, Charles-Edouard; Roche, Nicolas; Chalumeau, Martin; ... Brun-Buisson, Christian 2013
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Role of biomarkers in the management of antibiotic therapy: an expert panel review: I - currently available biomarkers for clinical use in acute infections Dupuy, Anne-Marie; Philippart, François; Péan, Yves; Lasocki, Sigismond; ... Brun-Buisson, Christian 2013
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Increased FGF21 plasma levels in humans with sepsis and SIRS. Gariani, Karim; Drifte Roduit, Geneviève Sophie; Dunn-Siegrist, Irène; Pugin, Jérôme; Jornayvaz, François 2013
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Traitement du choc septique par épuration extracorporelle de l’endotoxine circulante Gisselbaek, Mia; Pugin, Jérôme; Pavlovic, Gordana 2013
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Use of high-volume haemodiafiltration in patients with refractory septic shock and acute kidney injury Bourquin, Vincent; Ponte, Belen; Pugin, Jérôme; Martin, Pierre-Yves; Saudan, Patrick 2013
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Selective antibody intervention of Toll-like receptor 4 activation through Fc γ receptor tethering Shang, Limin; Daubeuf, Bruno; Triantafilou, Martha; Olden, Robin; ... Elson, Greg 2014
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Adrenomedullin: a vasodilator to treat sepsis? Pugin, Jérôme 2014
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Challenges in the culture-independent analysis of oral and respiratory samples from intubated patients Lazarevic, Vladimir; Gaia, Nadia; Emonet, Stéphane Paul; Girard, Myriam; ... Schrenzel, Jacques 2014
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Efficacy and safety of citrate-based anticoagulation compared to heparin in patients with acute kidney injury requiring continuous renal replacement therapy: a randomized controlled trial Stucker, Fabien Jérôme; Ponte, Belen; Tataw, James; Martin, Pierre-Yves; ... Saudan, Patrick 2015
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Augmented renal clearance, low β-lactam concentrations and clinical outcomes in the critically ill: An observational prospective cohort study Csaki Huttner, Angela; Von Dach, Elodie; Renzoni, Adriana Maria; Huttner, Benedikt; ... Harbarth, Stéphan Juergen 2015
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Clinical features and viral kinetics in a rapidly cured patient with Ebola virus disease: a case report Schibler, Manuel; Vetter, Pauline; Cherpillod, Pascal; Petty, Tom J; ... Kaiser, Laurent 2015
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Sepsis chez le sujet âgé : quelles spécificités ? Roux, Xavier; Huttner, Benedikt; Pugin, Jérôme; Prendki, Virginie; Reny, Jean-Luc 2016
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