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Lipolysis and alpha-aminoisobutyric acid uptake in isolated fat cells. Effects of insulin and lipolytic agents Vassalli, Jean-Dominique; Jeanrenaud, B. 1970
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Long-term exposure of isolated pancreatic islets to mannoheptulose: evidence for insulin degradation in the beta cell Halban, Philippe A.; Wollheim, C. B.; Blondel, B.; Renold, A. E. 1980
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Intracellular degradation of insulin stores by rat pancreatic islets in vitro. An alternative pathway for homeostasis of pancreatic insulin content Halban, Philippe A.; Wollheim, Claes 1980
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Insulin resistance is accompanied by impairment of amylase-gene expression in the exocrine pancreas of the obese Zucker rat Trimble, E. R.; Bruzzone, R.; Belin, Dominique 1986
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Spontaneous reassociation of dispersed adult rat pancreatic islet cells into aggregates with three-dimensional architecture typical of native islets Halban, Philippe A.; Powers, S. L.; George, K. L.; Bonner-Weir, S. 1987
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Molecular strategies for the treatment of diabetes Ferber, S.; Schnedl, W. J.; BeltrandelRio, H.; Irminger, J. C.; ... Newgard, C. B. 1994
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Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line Wang, Haiyan; Maechler, Pierre; Hagenfeldt-Johansson, Kerstin Arlette; Wollheim, Claes 1998
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Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis Maechler, Pierre; Wollheim, Claes 1999
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What couples glycolysis to mitochondrial signal generation in glucose-stimulated insulin secretion? Ishihara, Hisamitsu; Wollheim, Claes 2000
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GAD65-mediated glutamate decarboxylation reduces glucose-stimulated insulin secretion in pancreatic beta cells Rubi, Blanca; Ishihara, Hisamitsu; Hegardt, F G; Wollheim, Claes; Maechler, Pierre 2001
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The NC2 alpha and beta subunits play different roles in vivo Creton, Sandrine; Svejstrup, Jesper Q; Collart, Martine 2002
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Effect of rosiglitazone on the differential expression of diabetes-associated proteins in pancreatic islets of C57Bl/6 lep/lep mice Sanchez, Jean-Charles; Converset, Véronique; Nolan, Anna; Schmid, Gerhard; ... Cawthorne, Michael A 2002
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Phosphorylation of SNAP-25 on serine-187 is induced by secretagogues in insulin-secreting cells, but is not correlated with insulin secretion Gonelle-Gispert, Carmen; Costa, Maria; Takahashi, Masami; Sadoul, Karin; Halban, Philippe A. 2002
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Presynaptic remodeling contributes to activity-dependent synaptogenesis Nikonenko, Irina; Jourdain, Pascal; Muller, Dominique 2003
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Frequency and thermal effects on the enhancement of transdermal transport by sonophoresis Merino, Gustavo; Kalia, Yogeshvar; Delgado Charro, Maria Begona; Potts, Russell O; Guy, Richard H. 2003
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Assessment of hepatic glucose metabolism by indirect calorimetry in combination with a non-invasive technique using naturally enriched 13C glucose in healthy children and adolescents Selz, Roxane; Jornayvaz, François; Tappy, Luc; Woringer, Virgile; Theintz, Gérald E 2004
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Metabolism of oral glucose in children born small for gestational age: evidence for an impaired whole body glucose oxidation Jornayvaz, François; Selz, Roxane; Tappy, Luc; Theintz, Gerald E 2004
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The Ccr4-Not complex independently controls both Msn2-dependent transcriptional activation--via a newly identified Glc7/Bud14 type I protein phosphatase module--and TFIID promoter distribution Lenssen, Eve; James, Nicole; Pedruzzi, Ivo; Dubouloz, Frédérique; ... De Virgilio, Claudio 2005
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Does chasing selected 'Fox' to the nucleus prevent diabetes? Wang, Haiyan; Wollheim, Claes 2005
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A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling Knight, Zachary A; Gonzalez, Beatriz; Feldman, Morri E; Zunder, Eli R; ... Shokat, Kevan M 2006
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Effect of chronic hypoglycaemia on glucose concentration and glycogen content in rat brain: A localized 13C NMR study Lei, Hongxia; Gruetter, Rolf 2006
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MicroRNAs: 'ribo-regulators' of glucose homeostasis Gauthier, Benoît; Wollheim, Claes 2006
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Minireview: implication of mitochondria in insulin secretion and action Wiederkehr, Andreas; Wollheim, Claes 2006
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Brain energy metabolism and neurotransmission at near-freezing temperatures: in vivo (1)H MRS study of a hibernating mammal Henry, Pierre-Gilles; Russeth, Kevin P; Tkac, Ivan; Drewes, Lester R; ... Gruetter, Rolf 2007
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The right stuff: beta-cell channels, cycles, and sensors Halban, Philippe A. 2008
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Functional significance of repressor element 1 silencing transcription factor (REST) target genes in pancreatic beta cells Martin, David; Allagnat, F.; Chaffard, Gaelle; Caille, D.; ... Haefliger, J-A. 2008
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Synaptotagmin VII splice variants alpha, beta, and delta are expressed in pancreatic beta-cells and regulate insulin exocytosis Gauthier, Benoît; Duhamel, Dominique L.; Iezzi, Mariella; Theander, Sten; ... Wollheim, Claes 2008
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Munc 18-1 and granuphilin collaborate during insulin granule exocytosis Tomas Catala, Alejandra Del Don; Meda, Paolo; Regazzi, Romano; Pessin, Jeffrey E.; Halban, Philippe A. 2008
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Clusterin increases post-ischemic damages in organotypic hippocampal slice cultures Hakkoum, David; Imhof, Anouk; Vallet, Philippe; Boze, Helène; ... Giannakopoulos, Panteleimon 2008
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The endocannabinoid system and the control of glucose homeostasis Nogueiras, Rubén; Rohner-Jeanrenaud, Françoise; Woods, S C.; Tschöp, Matthias H. 2008
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Effects of gastric bypass and gastric banding on glucose kinetics and gut hormone release Rodieux, Frédérique; Giusti, Vittorio; D'Alessio, David A; Suter Ortiz, Michèle Seraphine; Tappy, Luc 2008
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Nuclear receptor agonists improve insulin responsiveness in cultured cardiomyocytes through enhanced signaling and preserved cytoskeletal architecture Montessuit, Christophe Albert; Papageorgiou, Irène; Lerch, René 2008
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Transient oxidative stress damages mitochondrial machinery inducing persistent beta-cell dysfunction Li, Ning; Brun, Thierry; Cnop, Miriam; Cunha, Daniel A.; ... Maechler, Pierre 2009
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Porcine marginal mass islet autografts resist metabolic failure over time and are enhanced by early treatment with liraglutide Emamaullee, Juliet A.; Merani, Shaheed; Toso, Christian; Kin, Tatsuya; ... Shapiro, A M James 2009
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Matrix alkalinization: a novel mitochondrial signal for sustained pancreatic beta-cell activation Wiederkehr, Andreas; Park, Kyu-Sang; Dupont, Olivier; Demaurex, Nicolas; ... Wollheim, Claes 2009
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Low- and high-density lipoproteins modulate function, apoptosis, and proliferation of primary human and murine pancreatic beta-cells Rütti, Sabine; Ehses, Jan A.; Sibler, Rahel A.; Prazak, Richard; ... von Eckardstein, Arnold 2009
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Mitochondrial glutamate carrier GC1 as a newly identified player in the control of glucose-stimulated insulin secretion Casimir, Marina Shamini; Lasorsa, Francesco M.; Rubi, Blanca; Caille, Dorothée; ... Maechler, Pierre 2009
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Host-derived glucose and its transporter in the obligate intracellular pathogen Toxoplasma gondii are dispensable by glutaminolysis Blume, Martin; Rodriguez-Contreras, Dayana; Landfear, Scott; Fleige, Tobias; ... Gupta, Nishith 2009
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Dynamin-related protein 1 mediates high glucose induced pancreatic beta cell apoptosis Men, Xiuli; Wang, Haiyan; Li, Mi; Cai, Hanqing; ... Lou, Jinning 2009
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Requirement for aralar and its Ca2+-binding sites in Ca2+ signal transduction in mitochondria from INS-1 clonal beta-cells Mármol, Patricia; Pardo, Beatriz; Wiederkehr, Andreas; del Arco, Araceli; ... Satrústegui, Jorgina 2009
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PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression Gauthier, Benoît; Wiederkehr, Andreas; Baquie, Mathurin; Dai, Chunhua; ... Wollheim, Claes 2009
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Alteration of brain glycogen turnover in the conscious rat after 5h of prolonged wakefulness Morgenthaler, Florence D; Lanz, Bernard R; Petit, Jean-Marie; Frenkel, Hanne; ... Gruetter, Rolf 2009
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The rate-limiting step for glucose transport into the hypothalamus is across the blood-hypothalamus interface Poitry-Yamate, Carole; Lei, Hongxia; Gruetter, Rolf 2009
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Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis Sumara, Grzegorz; Formentini, Ivan; Collins, Stephan; Sumara, Izabela; ... Ricci, Romeo 2009
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Hepatitis C virus and type 2 diabetes Negro, Francesco; Alaei, Mahnaz 2009
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PPARdelta is a fatty acid sensor that enhances mitochondrial oxidation in insulin-secreting cells and protects against fatty acid-induced dysfunction Ravnskjaer, Kim; Frigerio, Francesca; Boergesen, Michael; Nielsen, Tina; ... Mandrup, Susanne 2010
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Saturated fatty acid-induced insulin resistance is associated with mitochondrial dysfunction in skeletal muscle cells Hirabara, Sandro M.; Curi, Rui; Maechler, Pierre 2010
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Role of mitochondria in beta-cell function and dysfunction Maechler, Pierre; Li, Ning; Casimir, Marina Shamini; Vetterli, Laurene Marine; ... Brun, Thierry 2010
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Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation Wallin, Tina; Ma, Zuheng; Ogata, Hirotaka; Jørgensen, Ingrid Hals; ... Björklund, Anneli 2010
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Quantification of brain glycogen concentration and turnover through localized 13C NMR of both the C1 and C6 resonances van Heeswijk, Ruud B; Morgenthaler, Florence D; Xin, Lijing; Gruetter, Rolf 2010
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