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Bioactivation of the narcotic drug codeine in human liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation (cytochrome P-450 dbl/bufI) Dayer, Pierre; Desmeules, Jules Alexandre; Leemann, Thierry; Striberni, Rita 1988
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Impact of environmental and genetic factors on codeine analgesia Desmeules, Jules Alexandre; Gascon, Marie-Paule; Dayer, P; Magistris, M 1991
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In vitro forecasting of drugs that may interfere with codeine bioactivation Dayer, Pierre; Desmeules, Jules Alexandre; Striberni, Rita 1992
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Opposite effects of axon damage on heat shock proteins (hsp 70) and ubiquitin contents in motor neurons of neuropathic rats Lantéri-Minet, M; Desmeules, Jules Alexandre; Menetrey, Danila 1993
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The highly selective delta agonist BUBU induces an analgesic effect in normal and arthritic rat and this action is not affected by repeated administration of low doses of morphine Desmeules, Jules Alexandre; Kayser, V; Gacel, G; Guilbaud, Georges Silvain; Roques, B P 1993
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Selective opioid receptor agonists modulate mechanical allodynia in an animal model of neuropathic pain Desmeules, Jules Alexandre; Kayser, V; Guilbaud, Georges Silvain 1993
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The pharmacology of tramadol Dayer, P; Collart Leemann, Laurence; Desmeules, Jules Alexandre 1994
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Differential action of morphine and various opioid agonists on thermal allodynia and hyperalgesia in mononeuropathic rats Lee, S; Kayser, v; Desmeules, Jules Alexandre; Guilbaud, Georges Silvain 1994
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Pericardite recidivante induite par la mesalazine (5-ASA) Desmeules, Jules Alexandre; Vogt-Ferrier, Nicole Barbara; Loizeau, Sylviane; Angelillo-Scherrer, A; Dayer, P 1994
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Evaluation de la douleur chronique des patients d'age geriatrique Desmeules, Jules Alexandre; Allaz, Anne-Françoise; Binyet, S; Piguet, Valérie; ... Dayer, P 1994
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Arret de travail et comportement-maladie chez des patients souffrant de douleurs chroniques Allaz, Anne-Françoise; Binyet, S; Desmeules, Jules Alexandre; Piguet, Valérie; Dayer, P 1994
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Time-course of nociceptive disorders induced by chronic loose ligatures of the rat sciatic nerve and changes of the acetylcholinesterase transport along the ligated nerve Filliatreau, G; Attal, N; Hässig, R; Guilbaud, Georges Silvain; ... DiGiamberardino, L 1994
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Quelle posologie antalgique du paracetamol? Piguet, Valérie; Desmeules, Jules Alexandre; Collart Leemann, Laurence; Dayer, P 1994
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Facteurs predictifs d'une resistance au traitement des douleurs neuropathiques Desmeules, Jules Alexandre; Constantin, C; Allaz, Anne-Françoise; Piguet, Valérie; ... Dayer, P 1994
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Influence of the sympathetic nervous system in the development of abnormal pain-related behaviours in a rat model of neuropathic pain Desmeules, Jules Alexandre; Kayser, V; Weil-Fuggaza, J; Bertrand, A; Guilbaud, Georges Silvain 1995
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Systemic clonidine differentially modulates the abnormal reactions to mechanical and thermal stimuli in rats with peripheral mononeuropathy Kayser, V; Desmeules, Jules Alexandre; Guilbaud, Georges Silvain 1995
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Stereoselective interaction between piroxicam and acenocoumarol Bonnabry, Pascal; Desmeules, Jules Alexandre; Rudaz, Serge; Leemann, T.; ... Dayer, Pierre 1996
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Contribution of monoaminergic modulation to the analgesic effect of tramadol Desmeules, Jules Alexandre; Piguet, Valérie; Collart Leemann, Laurence; Dayer, Pierre 1996
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Atteintes hepatiques medicamenteuses, il faut y penser ! Oestreicher, M; Desmeules, Jules Alexandre; Giostra, Emiliano; Gross, B; ... Dayer, P 1996
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Pharmacologie du tramadol Dayer, Pierre; Desmeules, Jules Alexandre; Collart Leemann, Laurence 1997
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Influence du sexe sur la plainte douloureuse Piguet, Valérie; Desmeules, Jules Alexandre; Allaz, Anne-Françoise; Kondo-Oestreicher, M; ... Dayer, P 1998
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Use of the label "litigation neurosis" in patients with somatoform pain disorder Allaz, Anne-Françoise; Vannotti, M; Desmeules, Jules Alexandre; Piguet, Valérie; ... Dayer, Pierre 1998
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Influences génétiques et environnementales sur la neuromodulation et l’effet antinociceptif du dextromethorphan Oestreicher, M; Desmeules, Jules Alexandre; Piguet, Valérie; Allaz, Anne-Françoise; Dayer, P 1998
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Sodium stibogluconate (pentostan) overdose in a patient with acquired immunodeficiency syndrome Reymond, Jane Madelaine; Desmeules, Jules Alexandre 1998
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Lack of acetaminophen ceiling effect on R-III nociceptive flexion reflex Piguet, Valérie; Desmeules, Jules Alexandre; Dayer, Pierre 1998
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Facteurs associes aux douleurs cancereuses refractaires Piguet, Valérie; Desmeules, Jules Alexandre; Allaz, Anne-Françoise; Kondo Oestreicher, M; Dayer, P 1998
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Rhabdomyolysis after correction of hyponatremia due to psychogenic polydipsia possibly complicated by clozapine Wicki, Jacques; Rutschmann, Olivier Thierry; Burri, Haran Kumar; Vecchietti, Gianluca; Desmeules, Jules Alexandre 1998
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Anaphylactic shock induced by intraurethral use of chlorhexidine Wicki, J; Deluze, Christophe; Cirafici, L; Desmeules, Jules Alexandre 1999
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Contribution of cytochrome P-4502D6 phenotype to the neuromodulatory effects of dextromethorphan Desmeules, Jules Alexandre; Oestreicher, M K; Piguet, Valérie; Allaz, Anne-Françoise; Dayer, Pierre 1999
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The tramadol option Desmeules, Jules Alexandre 2000
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Effet analgesique des opiaces en usage cutane: quelle est leur efficacite? Rollason Gumprecht, Victoria; Desmeules, Jules Alexandre; Vogt-Ferrier, Nicole Barbara 2001
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Hepatitis associated with Kava, a herbal remedy for anxiety Escher, Marc; Desmeules, Jules Alexandre; Giostra, Emiliano; Mentha, Gilles 2001
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Advances with analgesics and NSAIDs for the treatment of spinal disorders Desmeules, Jules Alexandre; Cedraschi, Christine; Piguet, Valérie; Allaz, Anne-Françoise; Dayer, Pierre 2002
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Drug-induced epidermolysis bullosa acquisita with antibodies to type VII collagen Delbaldo, Catherine Suzanne; Chen, Meilin; Friedli, André; Prins, Christa; ... Borradori, Luca 2002
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Clinical pharmacology and rationale of analgesic combinations Desmeules, Jules Alexandre; Rollason Gumprecht, Victoria; Piguet, Valérie; Dayer, Pierre 2003
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Neurophysiologic evidence for a central sensitization in patients with fibromyalgia Desmeules, Jules Alexandre; Cedraschi, Christine; Rapiti Aylward, Elisabetta; Baumgartner, E; ... Vischer, T L 2003
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Rofecoxib interaction with oral anticoagulant acenocoumarol Girardin, François; Siegenthaler, Michèle Andrée; De Moerloose, Philippe; Desmeules, Jules Alexandre 2003
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Influence du cycle mentruel sur le seuil de la douleur expérimentale Besson, M.; Piguet, Valérie; Desmeules, Jules Alexandre; Kondo Ostreicher, Mitsuko; ... Dayer, P. 2004
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SIADH consecutive to ciprofloxacin intake Adler, Dan Elie; Voide, Cathy; Thorens, Jean-Benoit; Desmeules, Jules Alexandre 2004
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Fibromyalgia: a randomised, controlled trial of a treatment programme based on self management Cedraschi, Christine; Desmeules, Jules Alexandre; Rapiti Aylward, Elisabetta; Baumgartner, E; ... Vischer, T L 2004
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QT interval prolongation in patients on methadone with concomitant drugs Piguet, Valérie; Desmeules, Jules Alexandre; Ehret, Georg Benedikt; Stoller, Rudolf; Dayer, Pierre 2004
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Codeine intoxication associated with ultrarapid CYP2D6 metabolism Gasche, Yvan; Daali, Youssef; Fathi, Marc; Chiappe, Alberto; ... Desmeules, Jules Alexandre 2004
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Polymorphisme génétique et interactions médicamenteuses: leur importance dans le traitement de la douleur Samer, Caroline Flora; Piguet, Valérie; Dayer, Pierre; Desmeules, Jules Alexandre 2005
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Sélection d'un médicament dans une classe thérapeutique donnée : l'exemple des «inhibiteurs de l'HMG-CoA réductase» Girardin, François; Desmeules, Jules Alexandre; Dayer, Pierre 2005
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Systemic allergic reaction and diffuse bone pain after exposure to a preparation of betamethasone Ehret, Georg Benedikt; Deluze, Christophe; Dayer, Pierre; Desmeules, Jules Alexandre 2005
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Le traitement de l'hypertension artérielle : un défi pour le praticien Seboe, Paul; Pechere, Antoinette; Desmeules, Jules Alexandre; Dayer, Pierre 2005
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CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis Vuilleumier, Nicolas; Rossier, Michel; Chiappe, Alberto; Degoumois, Florence; ... Hochstrasser, Denis 2006
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Prise en charge médicamenteuse des troubles psychologiques et comportementaux lies à la démence Gillabert, Cédric François; Desmeules, Jules Alexandre; Vogt-Ferrier, Nicole Barbara; Dayer, Pierre 2006
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Entre sel et gènes ou pharmacogénomique des antihypertenseurs Ernandez, Thomas; Pechere, Antoinette; Dayer, Pierre; Desmeules, Jules Alexandre 2006
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Drug-induced long QT syndrome in injection drug users receiving methadone: high frequency in hospitalized patients and risk factors Ehret, Georg Benedikt; Voide, Cathy; Gex-Fabry, Marianne; Chabert, Jocelyne; ... Desmeules, Jules Alexandre 2006
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