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Degradation of pork insulin and biosynthetic human insulin in vitro and in vivo: a comparative study Halban, Philippe A.; Duckworth, W. C. 1981
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An excitatory effect of vasopressin on neuronal firing in the hippocampus: structure-activity studies Muhlethaler, Michel; Dreifuss, Jean-Jacques 1982
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Vasopressin excites hippocampal neurones Muhlethaler, Michel; Dreifuss, Jean-Jacques; Gahwiler, B. H. 1982
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Characterization of a uterine-type oxytocin receptor in the rat hippocampus Muhlethaler, Michel; Sawyer, W. H.; Manning, M. M.; Dreifuss, Jean-Jacques 1983
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The influence of aromatic substituents on the binding of substituted benzamides to dopamine D-2 receptors: congruent QSAR and MEP analyses Testa, Bernard; el Tayar, Nabil; Carrupt, Pierre-Alain; Van de Waterbeemd, Hans; ... Marsden, C. D. 1987
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Mapping the main immunogenic region and toxin-binding site of the nicotinic acetylcholine receptor Barkas, T.; Mauron, A; Roth, B.; Alliod, C.; ... Ballivet, M. 1987
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Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists el Tayar, Nabil; Carrupt, Pierre-Alain; Van de Waterbeemd, Hans; Testa, Bernard 1988
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Oxidation of rat insulin II, but not I, leads to anomalous elution profiles upon HPLC analysis of insulin-related peptides Gross, D.; Skvorak, A.; Hendrick, G.; Weir, G.; ... Halban, Philippe A. 1988
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DESBASE, a multiparameter substituent database Van de Waterbeemd, Hans; Carrupt, Pierre-Alain; el Tayar, Nabil 1989
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Pattern recognition study of QSAR substituent descriptors Van de Waterbeemd, Hans; el Tayar, Nabil; Carrupt, Pierre-Alain; Testa, Bernard 1989
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Multivariate data analyses of QSAR parameters Van de Waterbeemd, Hans; Testa, Bernard; Carrupt, Pierre-Alain; el Tayar, Nabil 1989
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Lipophilicity and conformational behaviour of substituted xanthines Walther, B.; Carrupt, Pierre-Alain; Van de Waterbeemd, Hans; el Tayar, Nabil; Testa, Bernard 1989
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Beta-adrenoceptor modeling based on MEP studies el Tayar, Nabil; Van de Waterbeemd, Hans; Carrupt, Pierre-Alain; Testa, Bernard 1989
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A unique signature identifies a family of zinc-dependent metallopeptidases Jongeneel, C Victor; Bouvier, Jacques; Bairoch, Amos Marc 1989
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Stereoelectronic study of zetidoline, a dopamine D2 receptor antagonist Collin, S.; Evrard, G.; Vercauteren, D. P.; Durant, F.; ... Testa, Bernard 1989
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MHC class II regulatory factor RFX has a novel DNA-binding domain and a functionally independent dimerization domain Reith, Walter; Herrero Sanchez, Carlos; Kobr, M.; Silacci, P.; ... Mach, Bernard 1990
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Toxication of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and analogs by monoamine oxidase. A structure-reactivity relationship study Maret, G.; el Tayar, Nabil; Carrupt, Pierre-Alain; Testa, Bernard; ... Baird, M. 1990
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Neutrophil bactericidal activity against Staphylococcus aureus adherent on biological surfaces. Surface-bound extracellular matrix proteins activate intracellular killing by oxygen-dependent and -independent mechanisms Hermann, M.; Jaconi, Marisa; Dahlgren, C.; Waldvogel, Francis; ... Lew, Daniel Pablo 1990
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Isolation of high-affinity murine interleukin 2 receptors as detergent-resistant membrane complexes Hoessli, Daniel; Poincelet, Monique; Rungger-Brandle, Elisabeth 1990
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Percutaneous penetration of drugs: a quantitative structure-permeability relationship study el Tayar, Nabil; Tsai, Ruey-Shiuan; Testa, Bernard; Carrupt, Pierre-Alain; ... Leo, A. 1991
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Quantitative structure-metabolism relationship analyses of MAO-mediated toxication of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and analogues Altomare, Cosimo; Carrupt, Pierre-Alain; Gaillard, Patrick; el Tayar, Nabil; ... Carotti, Angelo 1992
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Clathrin-coated pit-mediated receptor internalization. Role of internalization signals and receptor mobility Paccaud, Jean-Pierre; Reith, Walter; Johansson, B.; Magnusson, K. E.; ... Carpentier, J. L. 1993
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Clinical-pharmacology of oxicams - new insights into the mechanisms of their dose-dependent toxicity Albengres, E.; Urien, S.; Barre, J.; Nguyen, P.; ... Testa, Bernard 1993
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The importance of dominant negative effects of amino acid side chain substitution in peptide-MHC molecule interactions and T cell recognition Boehncke, Wolf-Henning; Takeshita, T.; Pendleton, C. D.; Houghten, R. A.; ... Germain, R. N. 1993
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Effects of solvation on the ionization and conformation of raclopride and other antidopaminergic 6-methoxysalicylamides: insight into the pharmacophore Tsai, Ruey-Shiuan; Carrupt, Pierre-Alain; Testa, Bernard; Gaillard, Patrick; ... Hogberg, Thomas 1993
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Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network Riederer, M A; Soldati, Thierry; Shapiro, A D; Lin, J; Pfeffer, S R 1994
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Structure-genotoxicity relationships of allylbenzenes and propenylbenzenes: a quantum chemical study Tsai, Ruey-Shiuan; Carrupt, Pierre-Alain; Testa, Bernard; Caldwell, J. 1994
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Second messenger specificity of the inositol trisphosphate receptor: reappraisal based on novel inositol phosphates DeLisle, S.; Radenberg, T.; Wintermantel, M. R.; Tietz, C.; ... Mayr, G. W. 1994
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A new genetic selection identifies essential residues in SecG, a component of the Escherichia coli protein export machinery Bost, S.; Belin, Dominique 1995
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Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) McNaught, K. S.; Thull, Ulrike; Carrupt, Pierre-Alain; Altomare, Cosimo; ... Marsden, C. D. 1995
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Structure-affinity relationships of baclofen and 3-heteroaromatic analogues Pirard, B.; Carrupt, Pierre-Alain; Testa, Bernard; Tsai, Ruey-Shiuan; ... Durant, F. 1995
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Inhibition of monoamine oxidase by isoquinoline derivatives. Qualitative and 3D-quantitative structure-activity relationships Thull, Ulrike; Kneubuhler, S.; Gaillard, Patrick; Carrupt, Pierre-Alain; ... McNaught, K. S. 1995
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Esters of L-dopa: structure-hydrolysis relationships and ability to induce circling behaviour in an experimental model of hemiparkinsonism Brunner-Guenat, M.; Carrupt, Pierre-Alain; Lisa, G.; Testa, Bernard; ... Ventura, P. 1995
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X-ray crystal structure, partitioning behavior, and molecular modeling study of piracetam-type nootropics: insights into the pharmacophore Altomare, Cosimo; Cellamare, S.; Carotti, Angelo; Casini, G.; ... Testa, Bernard 1995
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Inhibition of monoamine oxidase-B by 5H-indeno[1,2-c]pyridazines: biological activities, quantitative structure-activity relationships (QSARs) and 3D-QSARs Kneubuhler, S.; Thull, Ulrike; Altomare, Cosimo; Carta, V.; ... Testa, Bernard 1995
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A consensus motif in the RFX DNA binding domain and binding domain mutants with altered specificity Emery, P.; Strubin, M.; Hofmann, K.; Bucher, Philipp; ... Reith, Walter 1996
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Effects of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mitochondrial respiration McNaught, K. S.; Thull, Ulrike; Carrupt, Pierre-Alain; Altomare, Cosimo; ... Marsden, C. D. 1996
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Inhibition of [3H]dopamine uptake into striatal synaptosomes by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine McNaught, K. S.; Thull, Ulrike; Carrupt, Pierre-Alain; Altomare, Cosimo; ... Marsden, C. D. 1996
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Toxicity to PC12 cells of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine McNaught, K. S.; Thull, Ulrike; Carrupt, Pierre-Alain; Altomare, Cosimo; ... Marsden, C. D. 1996
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How do antibodies and lectins recognize histo-blood group antigens? A 3D-QSAR study by comparative molecular field analysis (CoMFA) Imberty, A.; Mollicone, R.; Mikros, E.; Carrupt, Pierre-Alain; ... Oriol, R. 1996
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Lipophilicity in molecular modeling Testa, Bernard; Carrupt, Pierre-Alain; Gaillard, Patrick; Billois, F.; Weber, P. 1996
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Transdermal delivery of peptides by iontophoresis Hirvonen, J; Kalia, Yogeshvar; Guy, Richard H. 1996
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Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models Gaillard, Patrick; Carrupt, Pierre-Alain; Testa, Bernard; Schambel, P. 1996
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Phalloidin binding and rheological differences among actin isoforms Allen, P. G.; Shuster, C. B.; Kas, J.; Chaponnier, Christine; ... Herman, I. M. 1996
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A systems approach to molecular structure, intermolecular recognition, and emergence-dissolvence in medicinal research Testa, Bernard; Kier, Lemont B.; Carrupt, Pierre-Alain 1997
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H3-receptor antagonists: synthesis and structure-activity relationships of para- and meta-substituted 4(5)-phenyl-2-[[2-[4(5)-imidazolyl]ethyl]thio]imidazoles Mor, M.; Bordi, F.; Silva, C.; Rivara, S.; ... Testa, Bernard 1997
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Pharmacologie du tramadol Dayer, Pierre; Desmeules, Jules Alexandre; Collart Leemann, Laurence 1997
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Structure-function analyses of the Ssc1p, Mdj1p, and Mge1p Saccharomyces cerevisiae mitochondrial proteins in Escherichia coli Deloche, Olivier; Kelley, William; Georgopoulos, C. 1997
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Structure-property relationships of trimetazidine derivatives and model compounds as potential antioxidants Ancerewicz, J.; Migliavacca, E.; Carrupt, Pierre-Alain; Testa, Bernard; ... Le Ridant, A. 1998
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Ligand specificity of the genetic variants of human alpha1-acid glycoprotein: generation of a three-dimensional quantitative structure-activity relationship model for drug binding to the A variant Herve, F.; Caron, Giulia; Duche, J. C.; Gaillard, Patrick; ... Testa, Bernard 1998
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