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Bioactivation of the narcotic drug codeine in human liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation (cytochrome P-450 dbl/bufI) Dayer, Pierre; Desmeules, Jules Alexandre; Leemann, Thierry; Striberni, Rita 1988
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In vitro forecasting of drugs that may interfere with codeine bioactivation Dayer, Pierre; Desmeules, Jules Alexandre; Striberni, Rita 1992
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Influence of rifampin on fleroxacin pharmacokinetics Schrenzel, Jacques; Dayer, Pierre; Leemann, Thierry; Weidekamm, E.; ... Lew, Daniel Pablo 1993
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Stereoselective interaction between piroxicam and acenocoumarol Bonnabry, Pascal; Desmeules, Jules Alexandre; Rudaz, Serge; Leemann, T.; ... Dayer, Pierre 1996
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Contribution of monoaminergic modulation to the analgesic effect of tramadol Desmeules, Jules Alexandre; Piguet, Valérie; Collart Leemann, Laurence; Dayer, Pierre 1996
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Pharmacologie du tramadol Dayer, Pierre; Desmeules, Jules Alexandre; Collart Leemann, Laurence 1997
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Use of the label "litigation neurosis" in patients with somatoform pain disorder Allaz, Anne-Françoise; Vannotti, M; Desmeules, Jules Alexandre; Piguet, Valérie; ... Dayer, Pierre 1998
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Lack of acetaminophen ceiling effect on R-III nociceptive flexion reflex Piguet, Valérie; Desmeules, Jules Alexandre; Dayer, Pierre 1998
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Contribution of cytochrome P-4502D6 phenotype to the neuromodulatory effects of dextromethorphan Desmeules, Jules Alexandre; Oestreicher, M K; Piguet, Valérie; Allaz, Anne-Françoise; Dayer, Pierre 1999
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Simultaneous stereoselective analysis of tramadol and its main phase I metabolites by on-line capillary zone electrophoresis-electrospray ionization mass spectrometry Rudaz, Serge; Cherkaoui, Samir; Dayer, Pierre; Fanali, Salvatore; Veuthey, Jean-Luc 2000
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Advances with analgesics and NSAIDs for the treatment of spinal disorders Desmeules, Jules Alexandre; Cedraschi, Christine; Piguet, Valérie; Allaz, Anne-Françoise; Dayer, Pierre 2002
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Clinical pharmacology and rationale of analgesic combinations Desmeules, Jules Alexandre; Rollason Gumprecht, Victoria; Piguet, Valérie; Dayer, Pierre 2003
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Neurophysiologic evidence for a central sensitization in patients with fibromyalgia Desmeules, Jules Alexandre; Cedraschi, Christine; Rapiti Aylward, Elisabetta; Baumgartner, E; ... Vischer, T L 2003
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QT interval prolongation in patients on methadone with concomitant drugs Piguet, Valérie; Desmeules, Jules Alexandre; Ehret, Georg Benedikt; Stoller, Rudolf; Dayer, Pierre 2004
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Codeine intoxication associated with ultrarapid CYP2D6 metabolism Gasche, Yvan; Daali, Youssef; Fathi, Marc; Chiappe, Alberto; ... Desmeules, Jules Alexandre 2004
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Polymorphisme génétique et interactions médicamenteuses: leur importance dans le traitement de la douleur Samer, Caroline Flora; Piguet, Valérie; Dayer, Pierre; Desmeules, Jules Alexandre 2005
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Sélection d'un médicament dans une classe thérapeutique donnée : l'exemple des «inhibiteurs de l'HMG-CoA réductase» Girardin, François; Desmeules, Jules Alexandre; Dayer, Pierre 2005
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Systemic allergic reaction and diffuse bone pain after exposure to a preparation of betamethasone Ehret, Georg Benedikt; Deluze, Christophe; Dayer, Pierre; Desmeules, Jules Alexandre 2005
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Le traitement de l'hypertension artérielle : un défi pour le praticien Seboe, Paul; Pechere, Antoinette; Desmeules, Jules Alexandre; Dayer, Pierre 2005
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Development and validation of a new reversed-phase ion pairing liquid chromatographic method with fluorescence detection for penciclovir analysis in plasma and aqueous humor Schenkel, F.; Rudaz, Serge; Daali, Youssef; Oestreicher, M Kondo; ... Dayer, Pierre 2005
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CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis Vuilleumier, Nicolas; Rossier, Michel; Chiappe, Alberto; Degoumois, Florence; ... Hochstrasser, Denis 2006
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Prise en charge médicamenteuse des troubles psychologiques et comportementaux lies à la démence Gillabert, Cédric François; Desmeules, Jules Alexandre; Vogt-Ferrier, Nicole Barbara; Dayer, Pierre 2006
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Entre sel et gènes ou pharmacogénomique des antihypertenseurs Ernandez, Thomas; Pechere, Antoinette; Dayer, Pierre; Desmeules, Jules Alexandre 2006
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Drug-induced long QT syndrome in injection drug users receiving methadone: high frequency in hospitalized patients and risk factors Ehret, Georg Benedikt; Voide, Cathy; Gex-Fabry, Marianne; Chabert, Jocelyne; ... Desmeules, Jules Alexandre 2006
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Anticoagulation orale et pharmacogénétique : perspectives pour la pratique clinique Benusiglio, Patrick Raphaël; Desmeules, Jules Alexandre; De Moerloose, Philippe; Dayer, Pierre 2007
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Pharmacokinetic and pharmacodynamic properties of buprenorphine after a single intravenous administration in healthy volunteers: a randomized, double-blind, placebo-controlled, crossover study Escher, Monica; Daali, Youssef; Chabert, Jocelyne; Hopfgartner, Gerard; ... Desmeules, Jules Alexandre 2007
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Patients' representations of antidepressants: a clue to nonadherence? Piguet, Valérie; Cedraschi, Christine; Dumont, Patricia; Desmeules, Jules Alexandre; ... Dayer, Pierre 2007
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Pharmacogenetics of analgesics: toward the individualization of prescription Rollason, Victoria; Samer, Caroline Flora; Piguet, Valérie; Dayer, Pierre; Desmeules, Jules Alexandre 2008
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La prescription « off-label » Blondon, Katherine; Desmeules, Jules Alexandre; Vogt-Ferrier, Nicole Barbara; Besson, Marie; ... Dayer, Pierre 2008
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New approaches to the pharmacotherapy of neuropathic pain Besson, Marie; Piguet, Valérie; Dayer, Pierre; Desmeules, Jules Alexandre 2008
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Development and validation of a chemical hydrolysis method for dextromethorphan and dextrophan determination in urine samples: application to the assessment of CYP2D6 activity in fibromyalgia patients Daali, Youssef; Cherkaoui, Samir; Doffey-Lazeyras, Fabienne; Dayer, Pierre; Desmeules, Jules Alexandre 2008
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Lack of interaction of the NMDA receptor antagonists dextromethorphan and dextrorphan with P-glycoprotein Kanaan, Mouna; Daali, Youssef; Dayer, Pierre; Desmeules, Jules Alexandre 2008
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Influence of ABCB1 gene polymorphisms and P-glycoprotein activity on cyclosporine pharmacokinetics in peripheral blood mononuclear cells in healthy volunteers Ansermot, Nicolas; Rebsamen, Michela; Chabert, Jocelyne; Fathi, Marc; ... Desmeules, Jules Alexandre 2008
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Low-energy femoral fractures associated with the long-term use of bisphosphonates: a case series from a Swiss university hospital Ing Lorenzini, Kuntheavy; Desmeules, Jules Alexandre; Plachta, Olivier; Suva, Domizio; ... Peter, Robin 2009
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Two-dimensional liquid chromatography-ion trap mass spectrometry for the simultaneous determination of ketorolac enantiomers and paracetamol in human plasma: application to a pharmacokinetic study Ing Lorenzini, Kuntheavy; Desmeules, Jules Alexandre; Besson, Marie; Veuthey, Jean-Luc; ... Daali, Youssef 2009
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The AmpliChip CYP450 test: cytochrome P450 2D6 genotype assessment and phenotype prediction Rebsamen, M C.; Desmeules, Jules Alexandre; Daali, Youssef; Chiappe, A.; ... Rossier, M. F. 2009
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Uptake/efflux transport of tramadol enantiomers and O-desmethyl-tramadol: focus on P-glycoprotein Kanaan, Mouna; Daali, Youssef; Dayer, Pierre; Desmeules, Jules Alexandre 2009
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P-glycoprotein is not involved in the differential oral potency of naloxone and naltrexone Kanaan, Mouna; Daali, Youssef; Dayer, Pierre; Desmeules, Jules Alexandre 2009
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Ritonavir inhibits the two main prasugrel bioactivation pathways in vitro: a potential drug-drug interaction in HIV patients Daali, Youssef; Ancrenaz, Virginie; Bosilkovska Weisskopf, Marija; Dayer, Pierre; Desmeules, Jules Alexandre 2011
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Automated system for on-line desorption of dried blood spots applied to LC/MS/MS pharmacokinetic study of flurbiprofen and its metabolite Deglon, Julien; Thomas, Aurélien; Daali, Youssef; Lauer, Estelle; ... Staub, Christian 2011
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A randomized, controlled trial validates a peripheral supra-additive antihyperalgesic effect of a paracetamol-ketorolac combination Ing Lorenzini, Kuntheavy; Besson, Marie; Daali, Youssef; Salomon, Denis; ... Desmeules, Jules Alexandre 2011
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ABCB1 polymorphisms and neuropsychiatric adverse events in oseltamivir-treated children during influenza H1N1/09 pandemia L'Huillier, Arnaud; Ing Lorenzini, Kuntheavy; Crisinel, Pierre-Alex; Rebsamen, Michela; ... Desmeules, Jules Alexandre 2011
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Oral flurbiprofen metabolic ratio assessment using a single-point dried blood spot Daali, Youssef; Samer, Caroline Flora; Deglon, Julien; Thomas, Aurélien; ... Desmeules, Jules Alexandre 2012
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Quel programme informatique de détection des interactions médicamenteuses néfastes ? Ing Lorenzini, Kuntheavy; Reutemann, Barbara; Samer, Caroline Flora; Guignard, Bertrand; ... Desmeules, Jules Alexandre 2012
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Fracture atypique du fémur sous bisphosphonates, un effet indésirable à ne pas manquer Ing Lorenzini, Kuntheavy; Meier, Raphaël; Suva, Domizio; Dayer, Pierre; ... Peter, Robin 2012
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Psychological distress in fibromyalgia patients: a role for catechol-O-methyl-transferase Val158met polymorphism Desmeules, Jules Alexandre; Piguet, Valérie; Besson, Marie; Chabert, Jocelyne; ... Cedraschi, Christine 2012
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The paraoxonase-1 pathway is not a major bioactivation pathway of clopidogrel in vitro Ancrenaz, Virginie; Desmeules, Jules Alexandre; James, Richard William; Fontana, Pierre; ... Daali, Youssef 2012
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Pharmacokinetic-pharmacodynamic modelling of opioids in healthy human volunteers. A minireview Ing Lorenzini, Kuntheavy; Daali, Youssef; Dayer, Pierre; Desmeules, Jules Alexandre 2012
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A simplified method for busulfan monitoring using dried blood spot in combination with liquid chromatography/tandem mass spectrometry Ansari Djaberi, Marc Georges; Uppugunduri Satyanarayana, Chakradhara Rao; Deglon, Julien; Théorêt, Yves; ... Daali, Youssef 2012
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Validation of the simplified UVB model to assess the pharmacodynamics of analgesics in healthy human volunteers Ing Lorenzini, Kuntheavy; Besson, Marie; Daali, Youssef; Salomon, Denis; ... Desmeules, Jules Alexandre 2012
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