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Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells Ishihara, Hisamitsu; Wang, Haiyan; Drewes, L R; Wollheim, Claes 1999
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What couples glycolysis to mitochondrial signal generation in glucose-stimulated insulin secretion? Ishihara, Hisamitsu; Wollheim, Claes 2000
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Beta-cell-targeted expression of a dominant-negative hepatocyte nuclear factor-1 alpha induces a maturity-onset diabetes of the young (MODY)3-like phenotype in transgenic mice Hagenfeldt-Johansson, K. A.; Herrera, Pedro Luis; Wang, Haiyan; Gjinovci, A.; ... Wollheim, Claes 2001
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Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation Wang, Haiyan; Maechler, Pierre; Ritz-Laser, B; Hagenfeldt-Johansson, Kerstin Arlette; ... Wollheim, Claes 2001
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GAD65-mediated glutamate decarboxylation reduces glucose-stimulated insulin secretion in pancreatic beta cells Rubi, Blanca; Ishihara, Hisamitsu; Hegardt, F G; Wollheim, Claes; Maechler, Pierre 2001
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Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues Antinozzi, Peter; Ishihara, Hisamitsu; Newgard, Christopher B; Wollheim, Claes 2002
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Islet beta-cell secretion determines glucagon release from neighbouring alpha-cells Ishihara, Hisamitsu; Maechler, Pierre; Gjinovci, Asllan; Herrera, Pedro Luis; Wollheim, Claes 2003
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Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stress Kirkpatrick, Clare; Wiederkehr, Andreas; Baquie, Mathurin; Akhmedov, Dmitry; ... Wollheim, Claes 2011