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 TitleAuthors / EditorsDate
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Cell growth control: little eukaryotes make big contributions De Virgilio, Claudio; Loewith, Robbie Joséph 2006
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The TOR signalling network from yeast to man De Virgilio, Claudio; Loewith, Robbie Joséph 2006
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A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling Knight, Zachary A; Gonzalez, Beatriz; Feldman, Morri E; Zunder, Eli R; ... Shokat, Kevan M 2006
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TOR signaling in growth and metabolism Wullschleger, Stephan; Loewith, Robbie Joséph; Hall, Michael N 2006
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Caffeine extends yeast lifespan by targeting TORC1 Wanke, Valeria; Cameroni, Elisabetta; Lempiainen, Aino; Piccolis, Manuele; ... De Virgilio, Claudio 2008
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The Vam6 GEF controls TORC1 by activating the EGO complex Binda, Matteo; Péli-Gulli, Marie-Pierre; Bonfils, Grégory; Panchaud, Nicolas; ... De Virgilio, Claudio 2009
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Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis Huber, Alexandre; Bodenmiller, Bernd; Lempiainen, Aino; Stahl, Michael; ... Loewith, Robbie Joséph 2009
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Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2 Feldman, Morris E; Apsel, Beth; Lempiainen, Aino; Loewith, Robbie Joséph; ... Shokat, Kevan M 2009
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Arsenic toxicity to Saccharomyces cerevisiae is a consequence of inhibition of the TORC1 kinase combined with a chronic stress response Hosiner, Dagmar; Lempiainen, Harri; Reiter, Wolfgang; Urban, Joerg; ... Schüller, Christoph 2009
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Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling Lempiainen, Harri; Lempiainen, Aino; Urban, Joerg; Dohnal, Ilse; ... Shore, David M. 2009
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Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology Guan, Xue Li; Souza, Cleiton; Pichler, Harald; Dewhurst, Gisele; ... Riezman, Howard 2009
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Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast Bodenmiller, Bernd; Wanka, Stefanie; Kraft, Claudine; Urban, Joerg; ... Aebersold, Ruedi 2010
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Chemical Biology Approaches to Membrane Homeostasis and Function Umebayashi, Miwa; Pineau, Ludovic; Hannich, Joerg Thomas; Zumbuehl, Andréas; ... Riezman, Howard 2011
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Mitochondrial genomic dysfunction causes dephosphorylation of Sch9 in the yeast Saccharomyces cerevisiae Kawai, Shigeyuki; Urban, Joerg; Piccolis, Manuele; Panchaud, Nicolas; ... Loewith, Robbie Joséph 2011
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Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L Huber, Alexandre; French, Sarah L; Tekotte, Hille; Yerlikaya, Seda; ... Loewith, Robbie Joséph 2011
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A brief history of TOR Loewith, Robbie Joséph 2011
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Target of rapamycin (TOR) in nutrient signaling and growth control Loewith, Robbie Joséph; Hall, Michael N 2011
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Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry Chen, Jun; Young, Susan M; Allen, Chris; Seeber, Andrew; ... Sklar, Larry A 2012
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Amino acid signaling in high definition Gaubitz, Christl; Loewith, Robbie Joséph 2012
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Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis Berchtold, Doris; Piccolis, Manuele; Chiaruttini, Nicolas; Riezman, Isabelle; ... Loewith, Robbie Joséph 2012
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Growth control: function follows form Loewith, Robbie Joséph 2013
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TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks Shimada, Kenji; Filipuzzi, Ireos; Stahl, Michael; Helliwell, Stephen B; ... Gasser, Susan Margaret 2013
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Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis da Silveira Dos Santos, Aline Xavier; Riezman, Isabelle; Aguilera-Romero, Maria Auxiliadora; David, Fabrice Pierre André; ... Riezman, Howard 2014
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Roles for PI(3,5)P2 in nutrient sensing through TORC1 Jin, Natsuko; Mao, Kai; Jin, Yui; Tevzadze, Gela Guram; ... Weisman, Lois S 2014
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A neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeast Kennedy, Michael A; Gable, Kenneth; Niewola-Staszkowska, Karolina; Abreu, Susana; ... Baetz, Kristin 2014
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Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2 Gaubitz, Christl; Oliveira, Taiana M; Prouteau, Manoel; Leitner, Alexander; ... Loewith, Robbie Joséph 2015
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Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways Rispal, Delphine; Eltschinger, Sandra; Stahl, Michael; Vaga, Stefania; ... Loewith, Robbie Joséph 2015
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Dual action antifungal small molecule modulates multidrug efflux and TOR signaling Shekhar-Guturja, Tanvi; Gunaherath, G M Kamal B; Wijeratne, E M Kithsiri; Lambert, Jean-Philippe; ... Cowen, Leah E 2016
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TORC2 Structure and Function Gaubitz, Christl; Prouteau, Manoel; Kusmider, Beata; Loewith, Robbie Joséph 2016
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A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction Kennedy, Michael A; Moffat, Tia C; Gable, Kenneth; Ganesan, Suriakarthiga; ... Baetz, Kristin 2016
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TORC1 and TORC2 work together to regulate ribosomal protein S6 phosphorylation in Saccharomyces cerevisiae Yerlikaya, Seda; Meusburger, Madeleine; Kumari, Romika; Huber, Alexandre; ... Loewith, Robbie Joséph 2016
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TOR Complexes and the Maintenance of Cellular Homeostasis Eltschinger, Sandra; Loewith, Robbie Joséph 2016
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TORC1 organized in inhibited domains (TOROIDs) regulate TORC1 activity Prouteau, Manoel; Desfosses, Ambroise; Sieben, Christian; Bourgoint, Clelia; ... Loewith, Robbie Joséph 2017
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Tensing Up for Lipid Droplet Formation Roux, Aurélien; Loewith, Robbie Joséph 2017
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A pathway of targeted autophagy is induced by DNA damage in budding yeast Eapen, Vinay V; Waterman, David P; Bernard, Amélie; Schiffmann, Nathan; ... Haber, James E 2017
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Reciprocal Regulation of Target of Rapamycin Complex 1 and Potassium Accumulation Primo, Cecilia; Ferri-Blázquez, Alba; Loewith, Robbie Joséph; Yenush, Lynne 2017
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Cryo-EM structure of Saccharomyces cerevisiae target of rapamycin complex 2 Karuppasamy, Manikandan; Kusmider, Beata; Oliveira, Taiana M; Gaubitz, Christl; ... Schaffitzel, Christiane 2017
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Decrease in plasma membrane tension triggers PtdIns(4,5)P2 phase separation to inactivate TORC2 Riggi, Margot; Niewola-Staszkowska, Karolina; Chiaruttini, Nicolas; Colom Diego, Adai; ... Loewith, Robbie Joséph 2018
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Regulation of Cellular Metabolism through Phase Separation of Enzymes Prouteau, Manoel; Loewith, Robbie Joséph 2018
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Sphingolipids and membrane targets for therapeutics Loewith, Robbie Joséph; Riezman, Howard; Winssinger, Nicolas 2019
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TORC2 controls endocytosis through plasma membrane tension Riggi, Margot; Bourgoint, Clelia; Macchione, Mariano; Matile, Stefan; ... Roux, Aurélien 2019