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Theory and practice of size exclusion chromatography for the analysis of protein aggregates Fekete, Szabolcs; Beck, Alain; Veuthey, Jean-Luc; Guillarme, Davy 2014
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Ion-exchange chromatography for the characterization of biopharmaceuticals Fekete, Szabolcs; Beck, Alain; Veuthey, Jean-Luc; Guillarme, Davy 2015
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Hydrophobic interaction chromatography for the characterization ofmonoclonal antibodies and related products Fekete, Szabolcs; Veuthey, Jean-Luc; Beck, Alain; Guillarme, Davy 2016
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Potential of hydrophilic interaction chromatography for the analyticalcharacterization of protein biopharmaceuticals Periat, Aurélie Claudine; Fekete, Szabolcs; Cusumano, Alessandra; Veuthey, Jean-Luc; ... Guillarme, Davy 2016
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Impact of organic modifier and temperature on protein denaturationin hydrophobic interaction chromatography Bobaly, Balazs; Beck, Alain; Veuthey, Jean-Luc; Guillarme, Davy; Fekete, Szabolcs 2016
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Practical method development for the separation of monoclonal antibodies and antibody-drug-conjugate species in hydrophobic interaction chromatoraphy, part 2: Optimization of the phase system Cusumano, Alessandra; Guillarme, Davy; Beck, Alain; Fekete, Szabolcs 2016
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Comparison of originator and biosimilar therapeutic monoclonal antibodies using comprehensive two-dimensional liquid chromatography coupled with time-of-flight mass spectrometry Sorensen, Matthew; Harmes, David C.; Stoll, Dwight R.; Staples, Gergory O.; ... Beck, Alain 2016
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Analysis of antibody-drug conjugates by comprehensive on-line two-dimensional hydrophobic interaction chromatography x reversed phase liquid chromatography hyphenated to high resolution mass spectrometry. I − Optimization of separation conditions Sarrut, Morgane; Corgier, Amélie; Fekete, Szabolcs; Guillarme, Davy; ... Heinisch, Sabine 2016
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Importance of vial shape and type on the reproducibility of sizeexclusion chromatography measurement of monoclonal antibodies Rodriguez Aller, Marta Ruth; Cusumano, Alessandra; Beck, Alain; Guillarme, Davy 2016
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A New Anti-CXCR4 Antibody That Blocks the CXCR4/SDF-1 Axis and Mobilizes Effector Cells Broussas, Matthieu; Boute, Nicolas; Akla, Barbara; Berger, Sven; ... Klinguer-Hamour, Christine 2016
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Development of a fast workflow to screen the charge variants of therapeutic antibodies Wagner-Rousset, Elsa; Fekete, Szabolcs; Morel-Chevillet, Laura; Colas, Olivier; ... Beck, Alain 2017
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Comprehensive study on the effects of sodium and potassiumadditives in size exclusion chromatographic separations of proteinbiopharmaceuticals Goyon, Alexandre; Beck, Alain; Veuthey, Jean-Luc; Guillarme, Davy; Fekete, Szabolcs 2017
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Analysis of recombinant monoclonal antibodies in hydrophilicinteraction chromatography: A generic method developmentapproach Bobaly, Balazs; D'Atri, Valentina; Beck, Alain; Guillarme, Davy; Fekete, Szabolcs 2017
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Protocols for the analytical characterization of therapeutic monoclonal antibodies. II – Enzymatic and chemical sample preparation Bobaly, Balazs; Goyon, Alexandre; D'Atri, Valentina; Colas, Olivier; ... Guillarme, Davy 2017
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Characterization of 30 therapeutic antibodies and related products by size exclusion chromatography: Feasibility assessment for future mass spectrometry hyphenation Goyon, Alexandre; D'Atri, Valentina; Colas, Olivier; Fekete, Szabolcs; ... Guillarme, Davy 2017
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Protocols for the analytical characterization of therapeutic monoclonal antibodies. I - Non-denaturing chromatographic techniques Goyon, Alexandre; D'Atri, Valentina; Bobaly, Balazs; Wagner-Rousset, Elsa; ... Guillarme, Davy 2017
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Monoclonal antibody N-glycosylation profiling using capillary electrophoresis – Mass spectrometry: Assessment and method validation Giorgetti, Jérémie; D'Atri, Valentina; Canonge, Julie; Lechner, Antony; ... François, Yannis-Nicolas 2018
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Current possibilities of liquid chromatography for the characterization of antibody-drug conjugates Bobaly, Balazs; Fleury, Sandrine; Beck, Alain; Veuthey, Jean-Luc; ... Fekete, Szabolcs 2018
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An Online Four-Dimensional HIC×SEC-IM×MS Methodology for Proof-of-Concept Characterization of Antibody Drug Conjugates Ehkirch, Antony; D'Atri, Valentina; Rouviere, Florent; Hernandez-Alba, Oscar; ... Cianferani, Sarah 2018
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Characterization of an antibody-drug conjugate by hydrophilic interaction chromatography coupled to mass spectrometry D'Atri, Valentina; Fekete, Szabolcs; Stoll, Dwight; Lauber, Matthew; ... Guillarme, Davy 2018
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Utility of a high coverage phenyl-bonding and wide-pore superficially porous particle for the analysis of monoclonal antibodies and relatedproducts Bobaly, Balazs; Lauber, Matthew; Beck, Alain; Guillarme, Davy; Fekete, Szabolcs 2018
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Development of Comprehensive Online Two-Dimensional Liquid Chromatography/Mass Spectrometry Using Hydrophilic Interaction and Reversed-Phase Separations for Rapid and Deep Profiling of Therapeutic Antibodies Stoll, Dwight R.; Harmes, David C.; Staples, Gregory O.; Potter, Oscar G.; ... Beck, Alain 2018
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Unraveling the mysteries of modern size exclusion chromatography – the way to achieve confident characterization of therapeutic proteins Goyon, Alexandre; Fekete, Szabolcs; Beck, Alain; Veuthey, Jean-Luc; Guillarme, Davy 2018
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High-resolution separation of monoclonal antibodies mixtures and their charge variants by an alternative and generic CZE method Goyon, Alexandre; Francois, Yannis Nicolas; Colas, Olivier; Beck, Alain; ... Guillarme, Davy 2018
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Protocols for the analytical characterization of therapeutic monoclonal antibodies. III – Denaturing chromatographic techniques hyphenated to mass spectrometry D'Atri, Valentina; Goyon, Alexandre; Bobaly, Balazs; Beck, Alain; ... Guillarme, Davy 2018
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Characterizing various monoclonal antibodies with milder reversed phase chromatography conditions Bobaly, Balazs; D'Atri, Valentina; Lauber, Matthew; Beck, Alain; ... Fekete, Szabolcs 2018
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Orthogonal Middle-up Approaches for Characterization of the Glycan Heterogeneity of Etanercept by Hydrophilic Interaction Chromatography Coupled to High-Resolution Mass Spectrometry D'Atri, Valentina; Nováková, Lucie; Fekete, Szabolcs; Stoll, Dwight; ... Guillarme, Davy 2019
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Optimization of MS-Compatible Mobile Phases for IEX Separation of Monoclonal Antibodies Farsang, Evelin; Murisier, Amarande; Horvath, Krisztián; Colas, Olivier; ... Fekete, Szabolcs 2019
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Tuning selectivity in cation-exchange chromatography applied for monoclonal antibody separations, part 2: Evaluation of recent stationary phases Murisier, Amarande; Farsang, Evelin; Horváth, Krisztián; Lauber, Matthew; ... Fekete, Szabolcs 2019
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Cutting-edge multi-level analytical and structural characterization of antibody-drug conjugates: present and future Beck, Alain; D'Atri, Valentina; Ehkirch, Anthony; Fekete, Szabolcs; ... Cianférani, Sarah 2019