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A generic workflow for the characterization of therapeutic monoclonal antibodies—application to daratumumab Duivelshof, Bastiaan; Fekete, Szabolcs; Guillarme, Davy; D'Atri, Valentina 2019
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A workflow for column interchangeability in liquid chromatographyusing modeling software and quality-by-design principles Kormany, Robert; Tamas, Katalin; Guillarme, Davy; Fekete, Szabolcs 2017
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Achievable separation performance and analysis time in current liquid chromatographic practice for monoclonal antibody separations Fekete, Szabolcs; Veuthey, Jean-Luc; Guillarme, Davy 2017
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Analysis of antibody-drug conjugates by comprehensive on-line two-dimensional hydrophobic interaction chromatography x reversed phase liquid chromatography hyphenated to high resolution mass spectrometry. I − Optimization of separation conditions Sarrut, Morgane; Corgier, Amélie; Fekete, Szabolcs; Guillarme, Davy; ... Heinisch, Sabine 2016
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Analysis of recombinant monoclonal antibodies by RPLC: Toward a generic method development approach Fekete, Szabolcs; Rudaz, Serge; Fekete, Jenő; Guillarme, Davy 2012
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Analysis of recombinant monoclonal antibodies in hydrophilicinteraction chromatography: A generic method developmentapproach Bobaly, Balazs; D'Atri, Valentina; Beck, Alain; Guillarme, Davy; Fekete, Szabolcs 2017
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Analytical strategies for the characterization of therapeutic monoclonal antibodies Fekete, Szabolcs; Gassner Perruche, Anne-Laure; Rudaz, Serge; Schappler, Julie; Guillarme, Davy 2013
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Apparent efficiency of serially coupled columns in isocratic and gradient elution modes Fekete, Szabolcs; Codesido Sanchez, Santiago; Rudaz, Serge; Guillarme, Davy; Horváth, Krisztián 2018
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Characterization of 30 therapeutic antibodies and related products by size exclusion chromatography: Feasibility assessment for future mass spectrometry hyphenation Goyon, Alexandre; D'Atri, Valentina; Colas, Olivier; Fekete, Szabolcs; ... Guillarme, Davy 2017
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Characterization of an antibody-drug conjugate by hydrophilic interaction chromatography coupled to mass spectrometry D'Atri, Valentina; Fekete, Szabolcs; Stoll, Dwight; Lauber, Matthew; ... Guillarme, Davy 2018
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Characterizing various monoclonal antibodies with milder reversed phase chromatography conditions Bobaly, Balazs; D'Atri, Valentina; Lauber, Matthew; Beck, Alain; ... Fekete, Szabolcs 2018
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Chromatographic, Electrophoretic, and Mass Spectrometric Methods for the Analytical Characterization of Protein Biopharmaceuticals Fekete, Szabolcs; Guillarme, Davy; Pat, Sandra; Koen, Sandra 2016
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Comparative study of recent wide-pore materials of different stationary phase morphology, applied for the reversed-phase analysis of recombinant monoclonal antibodies Fekete, Szabolcs; Veuthey, Jean-Luc; Eeltink, Sebastiaan; Guillarme, Davy 2013
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Comparison of liquid chromatography and supercritical luidchromatography coupled to compact single quadrupole massspectrometer for targeted in vitro metabolism assay Spaggiari, Dany; Mehl, Florence; Desfontaine, Vincent; Grand-Guillaume-Perrenoud, Alexandre; ... Guillarme, Davy 2014
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Comparison of originator and biosimilar therapeutic monoclonal antibodies using comprehensive two-dimensional liquid chromatography coupled with time-of-flight mass spectrometry Sorensen, Matthew; Harmes, David C.; Stoll, Dwight R.; Staples, Gergory O.; ... Beck, Alain 2016
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Comparison of the most recent chromatographic approaches applied for fast and high resolution separations: Theory and practice Fekete, Szabolcs; Veuthey, Jean-Luc; Guillarme, Davy 2015
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Comparison of various silica-based monoliths for the analysis of large biomolecules Vuignier, Karine; Fekete, Szabolcs; Carrupt, Pierre-Alain; Veuthey, Jean-Luc; Guillarme, Davy 2013
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Comprehensive study on the effects of sodium and potassiumadditives in size exclusion chromatographic separations of proteinbiopharmaceuticals Goyon, Alexandre; Beck, Alain; Veuthey, Jean-Luc; Guillarme, Davy; Fekete, Szabolcs 2017
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Computer assisted liquid chromatographic method development for the separation of therapeutic proteins Tyteca, Eva; Veuthey, Jean-Luc; Desmet, Gert; Guillarme, Davy; Fekete, Szabolcs 2016
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Computer-Assisted Method Development for Small and Large Molecules Fekete, Szabolcs; Kormàni, Robert; Guillarme, Davy 2017
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Computer-assisted UHPLC–MS method development and optimization for the determination of 24 antineoplastic drugs used in hospital pharmacy Guichard, Nicolas; Fekete, Szabolcs; Guillarme, Davy; Bonnabry, Pascal; Fleury, Sandrine 2019
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Contribution of various types of liquid chromatography–mass spectrometry instruments to band broadening in fast analysis Spaggiari, Dany; Fekete, Szabolcs; Eugster, Philippe; Veuthey, Jean-Luc; ... Guillarme, Davy 2013
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Critical evaluation of fast size exclusion chromatographic separations of protein aggregates, applying sub-2μm particles Fekete, Szabolcs; Ganzler, Katalin; Guillarme, Davy 2013
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Current and future trends in UHPLC Fekete, Szabolcs; Schappler, Julie; Veuthey, Jean-Luc; Guillarme, Davy 2014
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Current possibilities of liquid chromatography for the characterization of antibody-drug conjugates Bobaly, Balazs; Fleury, Sandrine; Beck, Alain; Veuthey, Jean-Luc; ... Fekete, Szabolcs 2018
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Cutting-edge multi-level analytical and structural characterization of antibody-drug conjugates: present and future Beck, Alain; D'Atri, Valentina; Ehkirch, Anthony; Fekete, Szabolcs; ... Cianférani, Sarah 2019
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Development of a fast workflow to screen the charge variants of therapeutic antibodies Wagner-Rousset, Elsa; Fekete, Szabolcs; Morel-Chevillet, Laura; Colas, Olivier; ... Beck, Alain 2017
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Evaluation of a new wide pore core–shell material (Aeris™ WIDEPORE) and comparison with other existing stationary phases for the analysis of intact proteins Fekete, Szabolcs; Berky, Róbert; Fekete, Jenő; Veuthey, Jean-Luc; Guillarme, Davy 2012
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Evaluation of recent very efficient wide-pore stationary phases for the reversed-phase separation of proteins Fekete, Szabolcs; Berky, Róbert; Fekete, Jenő; Veuthey, Jean-Luc; Guillarme, Davy 2012
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Evolution and Current Trends in Liquid and Supercritical Fluid Chromatography Fekete, Szabolcs; Grand-Guillaume-Perrenoud, Alexandre; Guillarme, Davy 2014
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High resolution reversed phase analysis of recombinant monoclonal antibodies by ultra-high pressure liquid chromatography column coupling Fekete, Szabolcs; Dong, Michael W.; Zhang, Taylor; Guillarme, Davy 2013
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Hydrophobic interaction chromatography for the characterization ofmonoclonal antibodies and related products Fekete, Szabolcs; Veuthey, Jean-Luc; Beck, Alain; Guillarme, Davy 2016
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Impact of mobile phase temperature on recovery and stability of monoclonal antibodies using recent reversed-phase stationary phases Fekete, Szabolcs; Rudaz, Serge; Veuthey, Jean-Luc; Guillarme, Davy 2012
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Impact of organic modifier and temperature on protein denaturationin hydrophobic interaction chromatography Bobaly, Balazs; Beck, Alain; Veuthey, Jean-Luc; Guillarme, Davy; Fekete, Szabolcs 2016
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Implementation of a generic liquid chromatographic methoddevelopment workflow: Application to the analysis ofphytocannabinoids and Cannabis sativa extracts Fekete, Szabolcs; Sadat-Noorbakhsh, Vida; Schelling, Cédric; Molnar, Imre; ... Veuthey, Jean-Luc 2018
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Importance of instrumentation for fast liquid chromatography in pharmaceutical analysis Fekete, Szabolcs; Kohler, Isabelle; Rudaz, Serge; Guillarme, Davy 2014
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Influence of connection tubing in modern size exclusionchromatography and its impact on the characterization of mAbs Fekete, Szabolcs; Guillarme, Davy 2018
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Ion-exchange chromatography for the characterization of biopharmaceuticals Fekete, Szabolcs; Beck, Alain; Veuthey, Jean-Luc; Guillarme, Davy 2015
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Is hydrophobic interaction chromatography the most suitable technique to characterize site-specific antibody-drug conjugates? D'Atri, Valentina; Pell, Reinhard; Clarke, Adrian; Guillarme, Davy; Fekete, Szabolcs 2019
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Korszerű méretkizáráso kromatográfia: fehérje aggregátumok elválasztása Fekete, Szabolcs; Fekete, Jenö; Guillarme, Davy 2016
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Maximizing kinetic performance in supercritical fluid chromatography using state-of-the-art instruments Grand-Guillaume-Perrenoud, Alexandre; Hamman, Chris; Goel, Meenakshi; Veuthey, Jean-Luc; ... Fekete, Szabolcs 2013
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Modern Column Technologies for the Analytical Characterization of Biopharmaceuticals in Various Liquid Chromatographic Modes Fekete, Szabolcs; Veuthey, Jean-Luc; Guillarme, Davy 2015
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New developments and possibilities of wide-pore superficially porous particle technology applied for the liquid chromatographic analysis of therapeutic proteins Bobaly, Balazs; Veuthey, Jean-Luc; Guillarme, Davy; Fekete, Szabolcs 2018
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New trends in reversed-phase liquid chromatographic separations of therapeutic peptides and proteins: Theory and applications Fekete, Szabolcs; Veuthey, Jean-Luc; Guillarme, Davy 2012
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Optimization of MS-Compatible Mobile Phases for IEX Separation of Monoclonal Antibodies Farsang, Evelin; Murisier, Amarande; Horvath, Krisztián; Colas, Olivier; ... Fekete, Szabolcs 2019
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Optimization of non-linear gradient in hydrophobic interaction chromatography for the analytical characterization of antibody-drug conjugates Bobaly, Balazs; Randazzo, Giuseppe Marco; Rudaz, Serge; Guillarme, Davy; Fekete, Szabolcs 2017
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Orthogonal Middle-up Approaches for Characterization of the Glycan Heterogeneity of Etanercept by Hydrophilic Interaction Chromatography Coupled to High-Resolution Mass Spectrometry D'Atri, Valentina; Nováková, Lucie; Fekete, Szabolcs; Stoll, Dwight; ... Guillarme, Davy 2019
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Potential of hydrophilic interaction chromatography for the analyticalcharacterization of protein biopharmaceuticals Periat, Aurélie Claudine; Fekete, Szabolcs; Cusumano, Alessandra; Veuthey, Jean-Luc; ... Guillarme, Davy 2016
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Practical method development for the separation of monoclonal antibodies and antibody-drug-conjugate species in hydrophobic interaction chromatoraphy, part 2: Optimization of the phase system Cusumano, Alessandra; Guillarme, Davy; Beck, Alain; Fekete, Szabolcs 2016
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Protocols for the analytical characterization of therapeutic monoclonal antibodies. I - Non-denaturing chromatographic techniques Goyon, Alexandre; D'Atri, Valentina; Bobaly, Balazs; Wagner-Rousset, Elsa; ... Guillarme, Davy 2017
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