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 TitleAuthors / EditorsDate
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A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets Marchetti, P; Lupi, R; Bugliani, Marco; Kirkpatrick, Clare; ... Dotta, F 2012
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A neuronal isoform of nitric oxide synthase expressed in pancreatic beta-cells controls insulin secretion Lajoix, A D; Reggio, H; Chardès, T; Péraldi-Roux, S; ... Gross, R 2001
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A Systems Genetics Approach Identifies Genes and Pathways for Type 2 Diabetes in Human Islets Taneera, Jalal; Lang, Stefan; Sharma, Amitabh; Fadista, Joao; ... Groop, Leif 2012
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Abnormal glucose metabolism accompanies failure of glucose to stimulate insulin release from a rat pancreatic cell line (RINm5F) Halban, Philippe A.; Praz, G. A.; Wollheim, Claes 1983
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Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells Epstein, Sharon; Kirkpatrick, Clare; Castillon, Guillaume Alain; Muniz, Manuel; ... Riezman, Howard 2012
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Acute von Willebrand factor secretion from the endothelium in vivo: assessment through plasma propeptide (vWf:AgII) Levels Vischer, Ulrich Max; Ingerslev, J; Wollheim, Claes; Mestries, J C; ... Kruithof, E K 1997
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Adenovirus-mediated silencing of synaptotagmin 9 inhibits Ca2+-dependent insulin secretion in islets Iezzi-Bakhtiari, Mariella; Eliasson, Lena; Fukuda, Mitsunori; Wollheim, Claes 2005
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Alpha-cells of the endocrine pancreas: 35 years of research but the enigma remains Gromada, Jesper; Franklin, Isobel; Wollheim, Claes 2007
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Amiloride derivatives induce apoptosis by depleting ER Ca(2+) stores in vascular endothelial cells Park, Kyu-Sang; Poburko, Damon; Wollheim, Claes; Demaurex, Nicolas 2009
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AMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through activation of the pro-apoptotic Bcl-2 homology domain-3-only protein BMF. Kilbride, Seán M; Farrelly, Angela M; Bonner, Caroline; Ward, Manus W; ... Prehn, Jochen H M 2010
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Autocrine regulation of endothelial exocytosis: von Willebrand factor release is induced by prostacyclin in cultured endothelial cells Vischer, Ulrich Max; Lang, U; Wollheim, Claes 1998
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Beta cell glutamate receptor antagonists: novel oral antidiabetic drugs? Wollheim, Claes; Maechler, Pierre 2015
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Beta-cell mitochondria and insulin secretion: messenger role of nucleotides and metabolites Wollheim, Claes; Maechler, Pierre 2002
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Beta-cell mitochondria in the regulation of insulin secretion: a new culprit in type II diabetes Wollheim, Claes 2000
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Beta-cell-targeted expression of a dominant-negative hepatocyte nuclear factor-1 alpha induces a maturity-onset diabetes of the young (MODY)3-like phenotype in transgenic mice Hagenfeldt-Johansson, K. A.; Herrera, Pedro Luis; Wang, Haiyan; Gjinovci, A.; ... Wollheim, Claes 2001
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Beta-cell-targeted expression of a dominant-negative mutant of hepatocyte nuclear factor-1alpha in mice: diabetes model with beta-cell dysfunction partially rescued by nonglucose secretagogues Winzell, Maria Sörhede; Pacini, Giovanni; Wollheim, Claes; Ahrén, Bo 2004
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Biphasic insulin release in rat islets of Langerhans and the role of Intracellular Ca++ stores Kikuchi, M; Wollheim, Claes; Siegel, Eberhard Gottfried; Renold, A E; Sharp, G 1979
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Bone morphogenetic protein 3 controls insulin gene expression and is down-regulated in INS-1 cells inducibly expressing a hepatocyte nuclear factor 1A-maturity-onset diabetes of the young mutation Bonner, Caroline; Farrelly, Angela M; Concannon, Caoimhín G; Dussmann, Heiko; ... Prehn, Jochen H M 2011
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Ca2+-independent insulin exocytosis induced by alpha-latrotoxin requires latrophilin, a G protein-coupled receptor Lang, Jochen; Ushkaryov, Y; Grasso, A; Wollheim, Claes 1998
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Calcium signalling: comparison of the role of Ca2+ influx in excitable endocrine and non-excitable myeloid cells Schlegel, Werner; Mollard, P.; Demaurex, Nicolas; Theler, J. M.; ... Wollheim, Claes 1993
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Calcium-induced insulin release in monolayer culture of the endocrine pancreas. Studies with ionophore A23187 Wollheim, Claes; Blondel, B; Trueheart, P A; Renold, A E; Sharp, G W 1975
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Characterization of pancreatic transcription factor Pdx-1 binding sites using promoter microarray and serial analysis of chromatin occupancy Keller, David M; McWeeney, Shannon; Arsenlis, Athanasios; Drouin, Jacques; ... Goodman, Richard H 2007
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Characterization of two distinct liver progenitor cell subpopulations of hematopoietic and hepatic origins Corcelle, Véronique; Stieger, B; Gjinovci, Aslan; Wollheim, Claes; Gauthier, Benoît 2006
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Chemotactic peptide activation of human neutrophils and HL-60 cells. Pertussis toxin reveals correlation between inositol trisphosphate generation, calcium ion transients, and cellular activation Krause, Karl-Heinz; Schlegel, Werner; Wollheim, Claes; Andersson, T.; ... Lew, Daniel Pablo 1985
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Cytoplasmic calcium ions and other signalling events in insulin secretion Wollheim, Claes; Pralong, William 1990
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Cytosolic free Ca2+ in insulin secreting cells and its regulation by isolated organelles Prentki, M; Wollheim, Claes 1984
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Defective Mitochondrial Function and Motility Due to Mitofusin 1 Overexpression in Insulin Secreting Cells Park, Kyu-Sang; Wiederkehr, Andreas; Wollheim, Claes 2012
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Desensitization of mitochondrial Ca2+ and insulin secretion responses in the beta cell Maechler, Pierre; Kennedy, Eleanor; Wang, Haiyan; Wollheim, Claes 1998
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DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets Hall, Elin; Dayeh, Tasnim; Kirkpatrick, Clare; Wollheim, Claes; ... Ling, Charlotte 2013
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Does chasing selected 'Fox' to the nucleus prevent diabetes? Wang, Haiyan; Wollheim, Claes 2005
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Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death Wobser, Hella; Düssmann, Heiko; Kögel, Donat; Wang, Haiyan; ... Prehn, Jochen H M 2002
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Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line Wang, Haiyan; Maechler, Pierre; Hagenfeldt-Johansson, Kerstin Arlette; Wollheim, Claes 1998
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Dual effect of cell-cell contact disruption on cytosolic calcium and insulin secretion Jaques, Fabienne; Jousset, Hélène; Tomas Catala, Alejandra Del Don; Prost, Anne-Lise; ... Halban, Philippe A. 2008
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Dynamin-related protein 1 mediates high glucose induced pancreatic beta cell apoptosis Men, Xiuli; Wang, Haiyan; Li, Mi; Cai, Hanqing; ... Lou, Jinning 2009
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Early activation of the fatty acid metabolism pathway by chronic high glucose exposure in rat insulin secretory beta-cells Coute, Yohann; Brunner, Yannick; Schvartz, Domitille; Hernandez, Celine; ... Sanchez, Jean-Charles 2010
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Effect of insulin on glucose- and arginine-stimulated somatostatin secretion from the isolated perfused rat pancreas Gerber, Pietro; Trimble, E R; Wollheim, Claes; Renold, A E 1981
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Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell Ofori, Jones K.; Salunkhe, Vishal A.; Bagge, Annika; Vishnu, Neelanjan; ... Esguerra, Jonathan L. S. 2017
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Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes Shcherbina, L.; Edlund, A.; Esguerra, J.L.S.; Abels, M.; ... Wierup, N. 2017
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Essential Role of Mitochondrial Ca2+ Uniporter in the Generation of Mitochondrial pH Gradient and Metabolism-Secretion Coupling in Insulin-releasing Cells Quan, Xianglan; Nguyen, Tuyet Thi; Choi, Seong-Kyung; Xu, Shanhua; ... Park, Kyu-Sang 2015
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Establishment of rat pancreatic endocrine cell lines by infection with simian virus 40 Niesor, E; Wollheim, Claes; Mintz, D; Blondel, B; ... Weil, R 1979
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Evidence against a direct role of klotho in insulin resistance Lorenzi, Olivier; Veyrat-Durebex, Christelle; Wollheim, Claes; Villemin, Pascal; ... Vischer, Ulrich Max 2010
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Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes Prasad, Rashmi B; Lessmark, Anna; Almgren, Peter; Kovacs, Györgyi; ... Groop, Leif 2016
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Experimental models of transcription factor-associated maturity-onset diabetes of the young Wang, Haiyan; Hagenfeldt-Johansson, Kerstin; Otten, L. A.; Gauthier, B. R.; ... Wollheim, Claes 2002
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Expression and localisation of synaptotagmin isoforms in endocrine beta-cells: their function in insulin exocytosis Gut, A; Kiraly-Borri, Catherine Eva; Fukuda, M; Mikoshiba, K; ... Lang, Jochen 2001
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Expression of alpha-1 proteinase inhibitor in human islet microvascular endothelial cells Lou, Jinning; Triponez, Frédéric; Oberholzer, José; Wang, Haiyan; ... Morel, Philippe 1999
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Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation Wallin, Tina; Ma, Zuheng; Ogata, Hirotaka; Jørgensen, Ingrid Hals; ... Björklund, Anneli 2010
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Foxa2 (HNF3beta) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin release Wang, Haiyan; Gauthier, Benoît; Hagenfeldt-Johansson, Kerstin Arlette; Iezzi-Bakhtiari, Mariella; Wollheim, Claes 2002
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Functional differences between rat islets of ventral and dorsal pancreatic origin Trimble, E. R.; Halban, Philippe A.; Wollheim, Claes; Renold, A. E. 1982
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GABA in the endocrine pancreas: its putative role as an islet cell paracrine-signalling molecule Franklin, Isobel; Wollheim, Claes 2004
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GAD65-mediated glutamate decarboxylation reduces glucose-stimulated insulin secretion in pancreatic beta cells Rubi, Blanca; Ishihara, Hisamitsu; Hegardt, F G; Wollheim, Claes; Maechler, Pierre 2001
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