| Title | Authors / Editors | Date |
unige:9918 |
3-Dimensional and Electronic Analysis of Na+-Dependent Antidopaminergic Agents - Tropapride and Zetidoline |
Collin, S.; Vercauteren, D. P.; Evrard, G.; Durant, F.; ... Testa, Bernard |
1986 |
unige:10010 |
8-Substituted Xanthines As Phosphodiesterase Inhibitors - Conformation-Dependent Lipophilicity and Structure-Activity-Relationships |
Walther, B.; Carrupt, Pierre-Alain; el Tayar, Nabil; Testa, Bernard |
1989 |
unige:9990 |
[Chirality and drugs] |
Testa, Bernard; Reist, Marianne; Carrupt, Pierre-Alain |
2000 |
unige:10594 |
A cellular automata model of diffusion in aqueous systems |
Kier, Lemont B.; Cheng, Chao-Kun; Testa, Bernard; Carrupt, Pierre-Alain |
1997 |
unige:10592 |
A cellular automata model of enzyme kinetics |
Kier, Lemont B.; Cheng, Chao-Kun; Testa, Bernard; Carrupt, Pierre-Alain |
1996 |
unige:10593 |
A cellular automata model of micelle formation |
Kier, Lemont B.; Cheng, Chao-Kun; Testa, Bernard; Carrupt, Pierre-Alain |
1996 |
unige:9940 |
A cellular automata model of the hydrophobic effect |
Kier, Lemont B.; Cheng, Chao-Kun; Testa, Bernard; Carrupt, Pierre-Alain |
1995 |
unige:10646 |
A continuous fluorimetric method to monitor the enzymatic hydrolysis of medicinal esters |
Salvi, A.; Mayer, J. M.; Carrupt, Pierre-Alain; Testa, Bernard |
1996 |
unige:121591 |
A graphical similarity function to help ligand docking to proteins based on the molecular lipophilicity potential : the case of the D2 dopamine receptor |
Carrupt, Pierre-Alain; Raynaud, Isabelle; McLoughlin, David; Bouchard, Géraldine; ... Testa, Bernard |
2004 |
unige:10619 |
A simple model to predict blood-brain barrier permeation from 3D molecular fields |
Ooms, F.; Weber, P.; Carrupt, Pierre-Alain; Testa, Bernard |
2002 |
unige:10659 |
A systems approach to molecular structure, intermolecular recognition, and emergence-dissolvence in medicinal research |
Testa, Bernard; Kier, Lemont B.; Carrupt, Pierre-Alain |
1997 |
unige:9958 |
A theoretical conformational study of substituted O-anisamides as models of a class of dopamine antagonists |
Pannatier, A.; Anker, L.; Testa, Bernard; Carrupt, Pierre-Alain |
1981 |
unige:10666 |
Additions et corrections : structure genotoxicity relationships of allylbenzenes and propenylbenzenes - A quantum-chemical Study |
Tsai, Ruey-Shiuan; Carrupt, Pierre-Alain; Testa, Bernard; Caldwell, J. |
1995 |
unige:9928 |
Beta-adrenoceptor modeling based on MEP studies |
el Tayar, Nabil; Van de Waterbeemd, Hans; Carrupt, Pierre-Alain; Testa, Bernard |
1989 |
unige:10576 |
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models |
Gaillard, Patrick; Carrupt, Pierre-Alain; Testa, Bernard; Schambel, P. |
1996 |
unige:10591 |
Blood-to-brain transfer of various oxicams: effects of plasma binding on their brain delivery |
Jolliet, Philippe; Simon, N.; Bree, F.; Urien, S.; ... Tillement, J. P. |
1997 |
unige:10641 |
Charge and delocalisation effects on the lipophilicity of protonable drugs |
Reymond, F.; Carrupt, Pierre-Alain; Testa, Bernard; Girault, H. H. |
1999 |
unige:10632 |
Chiral inversion and hydrolysis of thalidomide: mechanisms and catalysis by bases and serum albumin, and chiral stability of teratogenic metabolites |
Reist, Marianne; Carrupt, Pierre-Alain; Francotte, Eric; Testa, Bernard |
1998 |
unige:9981 |
Chirality in drug research - stereomania, stereophobia, or stereophilia |
Testa, Bernard; Carrupt, Pierre-Alain; Christiansen, L. H.; Christoffersen, P.; Reist, Marianne |
1993 |
unige:9887 |
Clinical-pharmacology of oxicams - new insights into the mechanisms of their dose-dependent toxicity |
Albengres, E.; Urien, S.; Barre, J.; Nguyen, P.; ... Testa, Bernard |
1993 |
unige:10548 |
Combined molecular lipophilicity descriptors and their role in understanding intramolecular effects |
Caron, Giulia; Reymond, F.; Carrupt, Pierre-Alain; Girault, H. H.; Testa, Bernard |
1999 |
unige:9991 |
Conformation, Electrostatic Potential and Pharmacophoric Pattern of Orthopramides and Other Dopamine Receptor Antagonists |
Testa, Bernard; Van de Waterbeemd, Hans; Carrupt, Pierre-Alain |
1986 |
unige:10543 |
Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase |
Bruhlmann, C.; Ooms, F.; Carrupt, Pierre-Alain; Testa, Bernard; ... Carotti, Angelo |
2001 |
unige:10648 |
Development of a capillary electrophoresis method to monitor protein oxidation and antioxidant protection |
Salvi, A.; Carrupt, Pierre-Alain; Testa, Bernard |
1999 |
unige:10556 |
Development of an in vitro rat intestine segmental perfusion model to investigate permeability and predict oral fraction absorbed |
Castella, M. E.; Reist, Marianne; Mayer, J. M.; Turban, J. J.; ... Carrupt, Pierre-Alain |
2006 |
unige:10634 |
Development of molecular hydrogen-bonding potentials (MHBPs) and their application to structure-permeation relations |
Rey, S.; Caron, Giulia; Ermondi, Giuseppe; Gaillard, Patrick; ... Testa, Bernard |
2001 |
unige:9966 |
Drug racemization and its significance in pharmaceutical research |
Reist, Marianne; Testa, Bernard; Carrupt, Pierre-Alain |
2003 |
unige:10560 |
Effects of charge and intramolecular structure on the lipophilicity of nitrophenols |
Chopineaux-Courtois, V.; Reymond, F.; Bouchard, Géraldine; Carrupt, Pierre-Alain; ... Girault, H. H. |
1999 |
unige:10606 |
Effects of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mitochondrial respiration |
McNaught, K. S.; Thull, Ulrike; Carrupt, Pierre-Alain; Altomare, Cosimo; ... Marsden, C. D. |
1996 |
unige:10662 |
Effects of Solvation on the Ionization and Conformation of Raclopride and Other Antidopaminergic 6-Methoxysalicylamides - Insight Into the Pharmacophore. [Erratum to document cited in CA118(7):51870w] |
Tsai, Ruey-Shiuan; Carrupt, Pierre-Alain; Testa, Bernard; Gaillard, Patrick; ... Hogberg, Thomas |
1993 |
unige:10663 |
Effects of solvation on the ionization and conformation of raclopride and other antidopaminergic 6-methoxysalicylamides: insight into the pharmacophore |
Tsai, Ruey-Shiuan; Carrupt, Pierre-Alain; Testa, Bernard; Gaillard, Patrick; ... Hogberg, Thomas |
1993 |
unige:10537 |
Electrochemical behaviour and antioxidant activity of some natural polyphenols |
Born, M.; Carrupt, Pierre-Alain; Zini, R.; Bree, F.; ... Testa, Bernard |
1996 |
unige:9890 |
Electronic and Conformational Effects on the Lipophilicity of Isomers and Analogs of the Neurotoxin 1-Methyl-4-Phenylpyridinium (Mpp+) |
Altomare, Cosimo; Carrupt, Pierre-Alain; el Tayar, Nabil; Testa, Bernard; Nagatsu, T. |
1991 |
unige:9889 |
Enantiomeric resolution of sulfoxides on a Dach-Dnb chiral stationary-phase : a quantitative structure-enantioselective retention relationship (Qserr) study |
Altomare, Cosimo; Carotti, Angelo; Cellamare, S.; Fanelli, F.; ... Testa, Bernard |
1993 |
unige:10647 |
Esterase-like activity of human serum albumin toward prodrug esters of nicotinic acid |
Salvi, A.; Carrupt, Pierre-Alain; Mayer, J. M.; Testa, Bernard |
1997 |
unige:9898 |
Esters of L-dopa: structure-hydrolysis relationships and ability to induce circling behaviour in an experimental model of hemiparkinsonism |
Brunner-Guenat, M.; Carrupt, Pierre-Alain; Lisa, G.; Testa, Bernard; ... Ventura, P. |
1995 |
unige:10626 |
Evaluation and prediction of drug permeation |
Pagliara, Alessandra; Reist, Marianne; Geinoz, S.; Carrupt, Pierre-Alain; Testa, Bernard |
1999 |
unige:10613 |
Evidence for the existence of [3H]-trimetazidine binding sites involved in the regulation of the mitochondrial permeability transition pore |
Morin, D.; Elimadi, A.; Sapena, R.; Crevat, A.; ... Tillement, J. P. |
1998 |
unige:10621 |
Exploration of the pharmacophore of 3-alkyl-5-arylimidazolidinediones as new CB(1) cannabinoid receptor ligands and potential antagonists: synthesis, lipophilicity, affinity, and molecular modeling |
Ooms, F.; Wouters, J.; Oscari, O.; Happaerts, T.; ... Lambert, D. M. |
2002 |
unige:10620 |
Exploration of the pharmacophore of 3-alkyl-5-arylimidazolidinediones as new CB1 cannabinoid receptor ligands and potential antagonists: Synthesis, lipophilicity, affinity, and molecular modeling : additions and corrections |
Ooms, F.; Wouters, J.; Oscari, O.; Happaerts, T.; ... Lambert, D. M. |
2002 |
unige:10584 |
Generalization of ionic partition diagrams to lipophilic compounds and to biphasic systems with variable phase volume ratios |
Gobry, V.; Ulmeanu, S. M.; Reymond, F.; Bouchard, Géraldine; ... Girault, H. H. |
2001 |
unige:10612 |
H3-receptor antagonists: synthesis and structure-activity relationships of para- and meta-substituted 4(5)-phenyl-2-[[2-[4(5)-imidazolyl]ethyl]thio]imidazoles |
Mor, M.; Bordi, F.; Silva, C.; Rivara, S.; ... Testa, Bernard |
1997 |
unige:9975 |
Hydration of substituted benzenes - experimental studies and relationship with lipophilicity |
Rothlisberger, T.; Testa, Bernard; Van de Waterbeemd, Hans; Carrupt, Pierre-Alain |
1989 |
unige:10671 |
Imidazole H3-antagonists: relationship between structure and ex vivo binding to rat brain H3-receptors |
Vacondio, F.; Mor, M.; Silva, C.; Zuliani, V.; ... Testa, Bernard |
2004 |
unige:10657 |
Immobilized artificial membrane HPLC in drug research |
Taillardat-Bertschinger, Agnès; Carrupt, Pierre-Alain; Barbato, F.; Testa, Bernard |
2003 |
unige:10658 |
Immobilized artificial membrane liquid chromatography: proposed guidelines for technical optimization of retention measurements |
Taillardat-Bertschinger, Agnès; Galland, Alexandra; Carrupt, Pierre-Alain; Testa, Bernard |
2002 |
unige:9924 |
Influence of lipophilicity and chirality on the selectivity of ligands for beta 1- and beta 2-adrenoceptors |
el Tayar, Nabil; Testa, Bernard; Van de Waterbeemd, Hans; Carrupt, Pierre-Alain; Kaumann, A. J. |
1988 |
unige:9997 |
Influence of stereochemical factors on the partition-coefficient of diastereoisomers in a biphasic octan-1-Ol water-system |
Tsai, Ruey-Shiuan; Carrupt, Pierre-Alain; Testa, Bernard; el Tayar, Nabil; ... Casy, A. F. |
1993 |
unige:10607 |
Inhibition of [3H]dopamine uptake into striatal synaptosomes by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine |
McNaught, K. S.; Thull, Ulrike; Carrupt, Pierre-Alain; Altomare, Cosimo; ... Marsden, C. D. |
1996 |
unige:9948 |
Inhibition of alpha-ketoglutarate dehydrogenase by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) |
McNaught, K. S.; Altomare, Cosimo; Cellamare, S.; Carotti, Angelo; ... Marsden, C. D. |
1995 |