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A consensus motif in the RFX DNA binding domain and binding domain mutants with altered specificity Emery, P.; Strubin, M.; Hofmann, K.; Bucher, Philipp; ... Reith, Walter 1996
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A large-scale protein-function database Apweiler, Rolf; Armstrong, Richard; Bairoch, Amos Marc; Cornish-Bowden, Athel; ... Tipton, Keith 2010
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A new genetic selection identifies essential residues in SecG, a component of the Escherichia coli protein export machinery Bost, S.; Belin, Dominique 1995
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A short amino-terminal part of Arabidopsis phytochrome A induces constitutive photomorphogenic response Viczián, András; Ádám, Éva; Wolf, Iris; Bindics, János; ... Nagy, Ferenc 2012
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A short peptide at the amino terminus of the Sendai virus C protein acts as an independent element that induces STAT1 instability Garcin, Dominique; Marq, Jean-Baptiste; Iseni, Frédéric; Martin, Stephen; Kolakofsky, Daniel 2004
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A systems approach to molecular structure, intermolecular recognition, and emergence-dissolvence in medicinal research Testa, Bernard; Kier, Lemont B.; Carrupt, Pierre-Alain 1997
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A unique signature identifies a family of zinc-dependent metallopeptidases Jongeneel, C Victor; Bouvier, Jacques; Bairoch, Amos Marc 1989
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Afibrinogénémie congénitale et contrôle de qualité de la sécrétion du fibrinogène Vu, Dung; Neerman Arbez, Marguerite 2006
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Amino acid residues essential for function of the MexF efflux pump protein of Pseudomonas aeruginosa Aires, J. R.; Pechere, Jean-Claude; Van Delden, Christian; Kohler, Thilo 2002
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An excitatory effect of vasopressin on neuronal firing in the hippocampus: structure-activity studies Muhlethaler, Michel; Dreifuss, Jean-Jacques 1982
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Antimitotic and antiproliferative activities of chalcones: forward structure-activity relationship Boumendjel, Ahcène; Boccard, Julien; Carrupt, Pierre-Alain; Nicolle, Edwige; ... Dumontet, Charles 2008
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Antioxidant profiles of new chemical entities as multifunctional hits for the treatment of neurodegenerative disorders Cressend, Delphine 2010
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Beta-adrenoceptor modeling based on MEP studies el Tayar, Nabil; Van de Waterbeemd, Hans; Carrupt, Pierre-Alain; Testa, Bernard 1989
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Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models Gaillard, Patrick; Carrupt, Pierre-Alain; Testa, Bernard; Schambel, P. 1996
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Bioactive Natural Products Prioritization Using Massive Multi-informational Molecular Networks Olivon, Florent; Allard, Pierre-Marie; Koval, Alexey; Righi, Davide; ... Litaudon, Marc 2017
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Biphenyl-4-yl-acrylohydroxamic acids: Identification of a novel indolyl-substituted HDAC inhibitor with antitumor activity Cincinelli, Raffaella; Zwick, Vincent; Musso, Loana; Zuco, Valentina; ... Dallavalle, Sabrina 2016
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Cell-based multi-substrate assay coupled to UHPLC-ESI-MS/MS for a quick identification of class-specific HDAC inhibitors Zwick, Vincent; Simoes Avello, Claudia; Cuendet, Muriel 2016
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Characterization of a uterine-type oxytocin receptor in the rat hippocampus Muhlethaler, Michel; Sawyer, W. H.; Manning, M. M.; Dreifuss, Jean-Jacques 1983
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Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor Mata, Miguel A; Satterly, Neal; Versteeg, Gijs A; Frantz, Doug; ... Fontoura, Beatriz M A 2011
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Clathrin-coated pit-mediated receptor internalization. Role of internalization signals and receptor mobility Paccaud, Jean-Pierre; Reith, Walter; Johansson, B.; Magnusson, K. E.; ... Carpentier, J. L. 1993
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Clinical-pharmacology of oxicams - new insights into the mechanisms of their dose-dependent toxicity Albengres, E.; Urien, S.; Barre, J.; Nguyen, P.; ... Testa, Bernard 1993
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Combining topology and sequence design for the discovery of potent antimicrobial peptide dendrimers against multidrug-resistant Pseudomonas aeruginosa Stach, Michaela; Siriwardena, Thissa N; Kohler, Thilo; Van Delden, Christian; ... Reymond, Jean-Louis 2014
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Conjugation of N-acylhydrazone and 1,2,4-oxadiazole leads to the identification of active antimalarial agents Dos Santos Filho, José Maurício; de Queiroz E Silva, Diogo Manoel Alves; Macedo, Taís Soares; Teixeira, Helena Mariana Pitangueira; ... Soares, Milena Botelho Pereira 2016
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Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase Bruhlmann, C.; Ooms, F.; Carrupt, Pierre-Alain; Testa, Bernard; ... Carotti, Angelo 2001
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Cross metathesis with hydroxamate and benzamide BOC-protected alkenes to access HDAC inhibitors and their biological evaluation highlighted intrinsic activity of BOC-protected dihydroxamates Zwick, Vincent; Nurisso, Alessandra; Simoes Avello, Claudia; Bouchet, Samuel; ... Bertrand, Philippe 2016
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Crucial role of aspartic acid at position 265 in the CH2 domain for murine IgG2a and IgG2b Fc-associated effector functions Baudino, Lucie Clementine; Shinohara, Yasuro; Nimmerjahn, Falk; Furukawa, Jun-ichi; ... Izui, Shozo 2008
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Degradation of pork insulin and biosynthetic human insulin in vitro and in vivo: a comparative study Halban, Philippe A.; Duckworth, W. C. 1981
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DESBASE, a multiparameter substituent database Van de Waterbeemd, Hans; Carrupt, Pierre-Alain; el Tayar, Nabil 1989
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Development of molecular hydrogen-bonding potentials (MHBPs) and their application to structure-permeation relations Rey, S.; Caron, Giulia; Ermondi, Giuseppe; Gaillard, Patrick; ... Testa, Bernard 2001
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Effects of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mitochondrial respiration McNaught, K. S.; Thull, Ulrike; Carrupt, Pierre-Alain; Altomare, Cosimo; ... Marsden, C. D. 1996
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Effects of solvation on the ionization and conformation of raclopride and other antidopaminergic 6-methoxysalicylamides: insight into the pharmacophore Tsai, Ruey-Shiuan; Carrupt, Pierre-Alain; Testa, Bernard; Gaillard, Patrick; ... Hogberg, Thomas 1993
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Engineering chemokines to develop optimized HIV inhibitors Hartley, Oliver; Offord, Robin Ewart 2005
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Esters of L-dopa: structure-hydrolysis relationships and ability to induce circling behaviour in an experimental model of hemiparkinsonism Brunner-Guenat, M.; Carrupt, Pierre-Alain; Lisa, G.; Testa, Bernard; ... Ventura, P. 1995
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Exploration of the pharmacophore of 3-alkyl-5-arylimidazolidinediones as new CB(1) cannabinoid receptor ligands and potential antagonists: synthesis, lipophilicity, affinity, and molecular modeling Ooms, F.; Wouters, J.; Oscari, O.; Happaerts, T.; ... Lambert, D. M. 2002
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Extraction of amino acids by reverse iontophoresis: simulation of therapeutic monitoring in vitro Sieg, Anke; Jeanneret, Fabienne; Fathi, Marc; Hochstrasser, Denis; ... Delgado-Charro, Begoña M. 2008
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GnRH antagonists: a new generation of long acting analogues incorporating p-ureido-phenylalanines at positions 5 and 6 Jiang, G; Stalewski, J; Galyean, R; Dykert, J; ... Rivier, J E 2001
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H3-receptor antagonists: synthesis and structure-activity relationships of para- and meta-substituted 4(5)-phenyl-2-[[2-[4(5)-imidazolyl]ethyl]thio]imidazoles Mor, M.; Bordi, F.; Silva, C.; Rivara, S.; ... Testa, Bernard 1997
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Highly potent HIV inhibition: engineering a key anti-HIV structure from PSC-RANTES into MIP-1 beta/CCL4 Gaertner, Hubert François; Lebeau, Olivier; Borlat, Irène; Cerini, Fabrice; ... Hartley, Oliver 2008
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How do antibodies and lectins recognize histo-blood group antigens? A 3D-QSAR study by comparative molecular field analysis (CoMFA) Imberty, A.; Mollicone, R.; Mikros, E.; Carrupt, Pierre-Alain; ... Oriol, R. 1996
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How many is enough? Exploring the myosin repertoire in the model eukaryote Dictyostelium discoideum Soldati, Thierry; Geissler, H; Schwarz, E C 1999
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Imidazole H3-antagonists: relationship between structure and ex vivo binding to rat brain H3-receptors Vacondio, F.; Mor, M.; Silva, C.; Zuliani, V.; ... Testa, Bernard 2004
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Immediate-early gene regulation by interplay between different post-translational modifications on human histone H3 Kaleem, Afshan; Hoessli, Daniel; Ahmad, Ishtiaq; Walker-Nasir, Evelyne; ... Nasir-ud-Din, 2008
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Immobilized artificial membrane HPLC in drug research Taillardat-Bertschinger, Agnès; Carrupt, Pierre-Alain; Barbato, F.; Testa, Bernard 2003
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Impact of species-dependent differences on screening, design, and development of MAO B inhibitors Novaroli, L.; Daina, Antoine; Favre, Elisabeth; Bravo, Juan; ... Reist, Marianne 2006
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Inherited dysfibrinogenemia: clinical phenotypes associated with five different fibrinogen structure defects Miesbach, Wolfgang; Scharrer, Inge; Henschen, Agnes; Neerman Arbez, Marguerite; ... Galanakis, Dennis 2010
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Inhibition of [3H]dopamine uptake into striatal synaptosomes by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine McNaught, K. S.; Thull, Ulrike; Carrupt, Pierre-Alain; Altomare, Cosimo; ... Marsden, C. D. 1996
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Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) McNaught, K. S.; Thull, Ulrike; Carrupt, Pierre-Alain; Altomare, Cosimo; ... Marsden, C. D. 1995
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Inhibition of monoamine oxidase by isoquinoline derivatives. Qualitative and 3D-quantitative structure-activity relationships Thull, Ulrike; Kneubuhler, S.; Gaillard, Patrick; Carrupt, Pierre-Alain; ... McNaught, K. S. 1995
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Inhibition of monoamine oxidase-B by 5H-indeno[1,2-c]pyridazines: biological activities, quantitative structure-activity relationships (QSARs) and 3D-QSARs Kneubuhler, S.; Thull, Ulrike; Altomare, Cosimo; Carta, V.; ... Testa, Bernard 1995
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Inhibition of monoamine oxidase-B by condensed pyridazines and pyrimidines: Effects of lipophilicity and structure-activity relationships Altomare, Cosimo; Cellamare, S.; Summo, L.; Catto, M.; ... Stoeckli-Evans, H. 1998
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