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 TitleAuthors / EditorsDate
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A cocktail approach for assessing the in vitro activity of human cytochrome P450s: An overview of current methodologies Spaggiari, Dany; Geiser, Laurent; Daali, Youssef; Rudaz, Serge 2014
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A randomized, controlled trial validates a peripheral supra-additive antihyperalgesic effect of a paracetamol-ketorolac combination Ing Lorenzini, Kuntheavy; Besson, Marie; Daali, Youssef; Salomon, Denis; ... Desmeules, Jules Alexandre 2011
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A simplified method for busulfan monitoring using dried blood spot in combination with liquid chromatography/tandem mass spectrometry Ansari Djaberi, Marc Georges; Uppugunduri Satyanarayana, Chakradhara Rao; Deglon, Julien; Théorêt, Yves; ... Daali, Youssef 2012
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An extensive cocktail approach for rapid risk assessment of in vitro CYP450 direct reversible inhibition by xenobiotic exposure Spaggiari, Dany; Daali, Youssef; Rudaz, Serge 2016
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Analgesics in patients with hepatic impairment: pharmacology and clinical implications Bosilkovska Weisskopf, Marija; Walder, Bernhard; Besson, Marie; Daali, Youssef; Desmeules, Jules Alexandre 2012
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Antihyperalgesic Effect of the GABA(A) Ligand Clobazam in a Neuropathic Pain Model in Mice: A Pharmacokinetic-Pharmacodynamic Study Besson, Marie; Daali, Youssef; Di Lio, Alessandra; Dayer, Pierre; ... Desmeules, Jules Alexandre 2013
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Antiplatelet Therapy: Targeting the TxA2 Pathway Fontana, Pierre; Zufferey Bakos, Anne; Daali, Youssef; Reny, Jean-Luc 2014
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Applications of CYP450 Testing in the Clinical Setting Samer, Caroline Flora; Ing Lorenzini, Kuntheavy; Rollason Gumprecht, Victoria; Daali, Youssef; Desmeules, Jules Alexandre 2013
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Aspirin response: Differences in serum thromboxane B2 levels between clinical studies Brun, Charlotte; Daali, Youssef; Combescure, Christophe; Zufferey Bakos, Anne; ... Frelinger, Andrew L (3rd) 2016
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Augmented renal clearance, low β-lactam concentrations and clinical outcomes in the critically ill: An observational prospective cohort study Csaki Huttner, Angela; Von Dach, Elodie; Renzoni, Adriana Maria; Huttner, Benedikt; ... Harbarth, Stéphan Juergen 2015
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Automated system for on-line desorption of dried blood spots applied to LC/MS/MS pharmacokinetic study of flurbiprofen and its metabolite Deglon, Julien; Thomas, Aurélien; Daali, Youssef; Lauer, Estelle; ... Staub, Christian 2011
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Calystegine distribution in some solanaceous species Bekkouche, K.; Daali, Youssef; Cherkaoui, Samir; Veuthey, Jean-Luc; Christen, Philippe 2001
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Capillary electrophoresis and high-performance anion exchange chromatography for monitoring caseinoglycomacropeptide sialylation Daali, Youssef; Cherkaoui, Samir; Veuthey, Jean-Luc 2001
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Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferases Romand, Stéphanie Anne; Spaggiari, Dany; Marsousi, Niloufar; Samer, Caroline Flora; ... Rudaz, Serge 2017
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Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approach Marsousi, Niloufar; Samer, Caroline Flora; Fontana, Pierre; Reny, Jean-Luc; ... Daali, Youssef 2016
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Codeine intoxication associated with ultrarapid CYP2D6 metabolism Gasche, Yvan; Daali, Youssef; Fathi, Marc; Chiappe, Alberto; ... Desmeules, Jules Alexandre 2004
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Complex Drug-Drug-Gene-Disease Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical Perspectives Storelli, Flavia; Samer, Caroline Flora; Reny, Jean-Luc; Desmeules, Jules Alexandre; Daali, Youssef 2018
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CYP450 activities before and after Roux-en-Y gastric bypass: correlation with their intestinal and liver content Lloret-Linares, Célia; Daali, Youssef; Abbara, Chadi; Carette, Claire; ... Declèves, Xavier 2019
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Detection of busulfan adducts on proteins Acosta Martin, Adelina Elena; Antinori Malaspina, Paola; Uppugunduri Satyanarayana, Chakradhara Rao; Daali, Youssef; ... Lescuyer, Pierre 2016
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Development and validation of a chemical hydrolysis method for dextromethorphan and dextrophan determination in urine samples: application to the assessment of CYP2D6 activity in fibromyalgia patients Daali, Youssef; Cherkaoui, Samir; Doffey-Lazeyras, Fabienne; Dayer, Pierre; Desmeules, Jules Alexandre 2008
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Development and validation of a new reversed-phase ion pairing liquid chromatographic method with fluorescence detection for penciclovir analysis in plasma and aqueous humor Schenkel, F.; Rudaz, Serge; Daali, Youssef; Oestreicher, M Kondo; ... Dayer, Pierre 2005
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Development and validation of liquid chromatography and capillary electrophoresis methods for acarbose determination in pharmaceutical tablets Cherkaoui, Samir; Daali, Youssef; Christen, Philippe; Veuthey, Jean-Luc 1998
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Dual reuptake inhibitor milnacipran and spinal pain pathways in fibromyalgia patients: a randomized, double-blind, placebo-controlled trial Matthey, Alain; Cedraschi, Christine; Piguet, Valérie; Besson, Marie; ... Desmeules, Jules Alexandre 2013
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Evaluation of Mutual Drug-Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method Bosilkovska Weisskopf, Marija; Samer, Caroline Flora; Deglon, Julien; Thomas, Aurélien; ... Daali, Youssef 2016
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Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis Seredenin, Tamara; Nayernia, Zeynab; Sorce, Silvia; Maghzal, Ghassan J; ... Jaquet, Vincent 2016
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Evidence of Drug-Drug Interactions through Uptake and Efflux Transport Systems in Rat Hepatocytes: Implications for Cellular Concentrations of Competing Drugs Daali, Youssef; Millet, Philippe; Dayer, Pierre; Pastor, Catherine 2013
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Evidence-Based Choice of P2Y12 Inhibitors in End Stage Renal Disease Patients: A Mini-Review Bouatou, Yassine; Samer, Caroline Flora; Fontana, Pierre; Daali, Youssef; Desmeules, Jules Alexandre 2015
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Experimental design for enantioselective separation of celiprolol by capillary electrophoresis using sulfated beta-cyclodextrin Daali, Youssef; Cherkaoui, Samir; Christen, Philippe; Veuthey, Jean-Luc 1999
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Exploring venlafaxine pharmacokinetic variability with a phenotyping approach, a multicentric french-swiss study (MARVEL study) Lloret-Linares, Célia; Daali, Youssef; Chevret, Sylvie; Nieto, Isabelle; ... Bellivier, Frank 2017
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GABAergic modulation in central sensitization in humans: a randomized placebo-controlled pharmacokinetic-pharmacodynamic study comparing clobazam with clonazepam in healthy volunteers Besson, Marie; Matthey, Alain; Daali, Youssef; Poncet, Antoine; ... Desmeules, Jules Alexandre 2015
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Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety Samer, Caroline Flora; Daali, Youssef; Wagner, M.; Hopfgartner, Gerard; ... Desmeules, Jules Alexandre 2010
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Geneva Cocktail for Cytochrome P450 and P-glycoprotein Activity Assessment Using Dried Blood Spots Bosilkovska Weisskopf, Marija; Samer, Caroline Flora; Deglon, Julien; Rebsamen, Michela; ... Daali, Youssef 2014
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Genotype-sensitive reversible and time-dependent CYP2D6 inhibition in human liver microsomes Storelli, Flavia; Desmeules, Jules Alexandre; Daali, Youssef 2018
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Hepatocyte Concentrations of Indocyanin Green (ICG) Reflects Transfer Rates Across Membrane Transporters Cusin, Fabien; Azevedo, Liliana; Bonnaventure, Pierre; Desmeules, Jules Alexandre; ... Pastor, Catherine 2017
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High performance liquid chromatography of acarbose and its metabolite on porous graphitic carbon column Daali, Youssef; Cherkaoui, Samir; Cahours, Xavier; Varesio, Emmanuel; Veuthey, Jean-Luc 2002
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How organic anions accumulate in hepatocytes lacking Mrp2: evidence in rat liver Millet, Philippe; Moulin, Marcelle; Stieger, Bruno; Daali, Youssef; Pastor, Catherine 2011
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HZ166, a novel GABAA receptor subtype-selective benzodiazepine site ligand, is antihyperalgesic in mouse models of inflammatory and neuropathic pain Di Lio, Alessandra; Benke, Dietmar; Besson, Marie; Desmeules, Jules Alexandre; ... Zeilhofer, Hanns Ulrich 2011
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Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites Marsousi, Niloufar; Daali, Youssef; Fontana, Pierre; Reny, Jean-Luc; ... Samer, Caroline Flora 2018
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Impact of CYP2D6 functional allelic variations on phenoconversion and drug-drug interactions Storelli, Flavia; Matthey, Alain; Lenglet, Sébastien; Thomas, Aurélien; ... Daali, Youssef 2017
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Impact of genetic polymorphisms and drug-drug interactions on clopidogrel and prasugrel response variability Ancrenaz, Virginie; Daali, Youssef; Fontana, Pierre; Besson, M.; ... Desmeules, Jules Alexandre 2010
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Incorporation of Flurbiprofen in a 4-Drug Cytochrome P450 Phenotyping Cocktail Bosilkovska Weisskopf, Marija; Clement, Mallorie; Dayer, Pierre; Desmeules, Jules Alexandre; Daali, Youssef 2014
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Influence of ABCB1 gene polymorphisms and P-glycoprotein activity on cyclosporine pharmacokinetics in peripheral blood mononuclear cells in healthy volunteers Ansermot, Nicolas; Rebsamen, Michela; Chabert, Jocelyne; Fathi, Marc; ... Desmeules, Jules Alexandre 2008
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Influence of CYP2D6 activity on pre-emptive analgesia by the N-methyl-D-aspartate antagonist dextromethorphan in a randomized controlled trial of acute pain Ehret, Georg Benedikt; Daali, Youssef; Chabert, Jocelyne; Rebsamen, Michela; ... Desmeules, Jules Alexandre 2013
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Influence of the paraoxonase-1 Q192R genetic variant on clopidogrel responsiveness and recurrent cardiovascular events: a systematic review and meta-analysis Reny, Jean-Luc; Combescure, Christophe; Daali, Youssef; Fontana, Pierre 2012
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Intestinal permeability and P-glycoprotein-mediated efflux transport of ticagrelor in Caco-2 monolayer cells Marsousi, Niloufar; Doffey-Lazeyras, Fabienne; Rudaz, Serge; Desmeules, Jules Alexandre; Daali, Youssef 2016
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Intraocular penetration of penciclovir after oral administration of famciclovir: a population pharmacokinetic model Schenkel, Fanny; Csajka, Chantal; Baglivo, Edoardo; Kondo Ostreicher, Mitsuko; ... Daali, Youssef 2013
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Lack of interaction of the NMDA receptor antagonists dextromethorphan and dextrorphan with P-glycoprotein Kanaan, Mouna; Daali, Youssef; Dayer, Pierre; Desmeules, Jules Alexandre 2008
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Liver kidney microsomal type 1 antibodies reduce the CYP2D6 activity in patients with chronic hepatitis C virus infection Girardin, François; Daali, Youssef; Gex-Fabry, Marianne; Rebsamen, Michela; ... Desmeules, Jules Alexandre 2012
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Markers of Individual Drug Metabolism: Towards the Development of a Personalized Antidepressant Prescription Lloret-Linares, Celia; Bellivier, Frank; Haffen, Emmanuel; Aubry, Jean-Michel; ... Besson, Marie 2015
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Molecular imaging reveals rapid reduction of endothelial activation in early atherosclerosis with apocynin independent of antioxidative properties Khanicheh, Elham; Qi, Yue; Xie, Aris; Mitterhuber, Martina; ... Kaufmann, Beat A 2013
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