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 TitleAuthors / EditorsDate
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Mitochondrial function and insulin secretion Maechler, Pierre 2013
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Mitochondrial function in normal and diabetic beta-cells Maechler, Pierre; Wollheim, Claes 2001
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Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis Maechler, Pierre; Wollheim, Claes 1999
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Mitochondrial glutamate carrier GC1 as a newly identified player in the control of glucose-stimulated insulin secretion Casimir, Marina Shamini; Lasorsa, Francesco M.; Rubi, Blanca; Caille, Dorothée; ... Maechler, Pierre 2009
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Mitochondrial hormesis in pancreatic β cells: does uncoupling protein 2 play a role? Li, Ning; Stojanovski, Suzana; Maechler, Pierre 2012
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Mitochondrial signal transduction in pancreatic β-cells Maechler, Pierre 2012
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Mitochondrial signals in glucose-stimulated insulin secretion in the beta cell Maechler, Pierre; Wollheim, Claes 2000
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Modulation of glutamate generation in mitochondria affects hormone secretion in INS-1E beta cells Maechler, Pierre; Antinozzi, Peter; Wollheim, Claes 2000
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NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion Li, Ning; Li, Bin; Brun, Thierry; Deffert-Delbouille, Christine; ... Maechler, Pierre 2012
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Non-invasive imaging of ferucarbotran labeled INS-1E cells and rodent islets in vitro and in transplanted diabetic rats Auer, Veronika J; Bucher, Julian; Schremmer-Danninger, Elisabeth; Paulmurugan, Ramasamy; ... Berger, Frank 2011
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Novel hexahydropyridoindole derivative as prospective agent against oxidative damage in pancreatic β cells Račková, Lucia; Cumaoğlu, Ahmet; Bağrıacık, E Umit; Štefek, Milan; ... Karasu, Çimen 2011
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Overexpression of the malate-aspartate NADH shuttle member Aralar1 in the clonal beta-cell line BRIN-BD11 enhances amino-acid-stimulated insulin secretion and cell metabolism Bender, Katrin; Maechler, Pierre; McClenaghan, Neville H.; Flatt, Peter R.; Newsholme, Philip 2009
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Pancreatic polypeptide regulates glucagon release through PPYR1 receptors expressed in mouse and human alpha-cells Aragón, F; Karaca Emre, Melis; Novials, A; Maldonado, R; ... Rubí, B 2015
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Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation Wang, Haiyan; Maechler, Pierre; Ritz-Laser, B; Hagenfeldt-Johansson, Kerstin Arlette; ... Wollheim, Claes 2001
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Peroxisome proliferator-activated receptor alpha (PPARalpha) protects against oleate-induced INS-1E beta cell dysfunction by preserving carbohydrate metabolism Frigerio, Francesca; Brun, Thierry; Bartley, C.; Usardi, A.; ... Maechler, Pierre 2010
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PPARdelta is a fatty acid sensor that enhances mitochondrial oxidation in insulin-secreting cells and protects against fatty acid-induced dysfunction Ravnskjaer, Kim; Frigerio, Francesca; Boergesen, Michael; Nielsen, Tina; ... Mandrup, Susanne 2010
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Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA Parone, Philippe; Da Cruz, Sandrine; Tondera, Daniel; Mattenberger, Yves Benoît; ... Martinou, Jean-Claude 2008
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Procyanidins modify insulinemia by affecting insulin production and degradation Castell-Auví, Anna; Cedó, Lídia; Pallarès, Victor; Blay, M Teresa; ... Ardévol, Anna 2012
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Reactive oxygen metabolites increase mitochondrial calcium in endothelial cells: implication of the Ca2+/Na+ exchanger Jornot, L; Maechler, Pierre; Wollheim, Claes; Junod, A F 1999
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Reply to Mishra: prohibitin heterodimers—a complex time dependence for carcinogenesis Martin-Levilain, Juliette; Li, Lingzi; Maechler, Pierre 2019
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Resveratrol long-term treatment differentiates INS-1E beta-cell towards improved glucose response and insulin secretion Casimir, Marina Shamini; Chaffard, Gaelle; Maechler, Pierre 2019
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Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism Vetterli, Laurene Marine; Brun, Thierry; Giovannoni, Laurianne; Bosco, Domenico; Maechler, Pierre 2011
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Resveratrol-activated SIRT1 in liver and pancreatic β-cells: a Janus head looking to the same direction of metabolic homeostasis Vetterli, Laurene Marine; Maechler, Pierre 2011
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Role of mitochondria in beta-cell function and dysfunction Maechler, Pierre; Li, Ning; Casimir, Marina Shamini; Vetterli, Laurene Marine; ... Brun, Thierry 2010
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Role of mitochondria in metabolism-secretion coupling of insulin release in the pancreatic beta-cell Maechler, Pierre; Wollheim, Claes 1998
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Saturated fatty acid-induced insulin resistance is associated with mitochondrial dysfunction in skeletal muscle cells Hirabara, Sandro M.; Curi, Rui; Maechler, Pierre 2010
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Sclerocarya birrea (Anacardiaceae) stem-bark extract corrects glycaemia in diabetic rats and acts on beta-cells by enhancing glucose-stimulated insulin secretion Makom Ndifossap, Ivonne Gisele; Frigerio, Francesca; Casimir, Marina Shamini; Ngueguim Tsofack, Florence; ... Maechler, Pierre 2010
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Silencing of the mitochondrial NADH shuttle component aspartate-glutamate carrier AGC1/Aralar1 in INS-1E cells and rat islets Casimir, Marina Shamini; Rubi, Blanca; Frigerio, Francesca; Chaffard, Gaelle; Maechler, Pierre 2009
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Small molecule kaempferol modulates PDX-1 protein expression and subsequently promotes pancreatic β-cell survival and function via CREB. Zhang, Yanling; Zhen, Wei; Maechler, Pierre; Liu, Dongmin 2013
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The Amplifying Pathway of the β-Cell Contributes to Diet-induced Obesity Vetterli, Laurene Marine; Carobbio, Stefania; Frigerio, Francesca; Karaca Emre, Melis; Maechler, Pierre 2016
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The dopamine receptor D2 agonist bromocriptine inhibits glucose-stimulated insulin secretion by direct activation of the alpha2-adrenergic receptors in beta cells de Leeuw van Weenen, J. E.; Parlevliet, E. T.; Maechler, Pierre; Havekes, L. M.; ... Guigas, B. 2010
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The sensitivity of pancreatic beta-cells to mitochondrial injuries triggered by lipotoxicity and oxidative stress Li, Ning; Frigerio, Francesca; Maechler, Pierre 2008
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Tissue specificity of mitochondrial glutamate pathways and the control of metabolic homeostasis Frigerio, Francesca; Casimir, Marina Shamini; Carobbio, Stefania; Maechler, Pierre 2008
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Transglutaminase 2 transamidation activity during first-phase insulin secretion: natural substrates in INS-1E. Russo, Lucia; Marsella, Claudia; Nardo, Giovanni; Massignan, Tania; ... Massa, Ornella 2013
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Transient oxidative stress damages mitochondrial machinery inducing persistent beta-cell dysfunction Li, Ning; Brun, Thierry; Cnop, Miriam; Cunha, Daniel A.; ... Maechler, Pierre 2009
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Upregulation of UCP2 in beta-cells confers partial protection against both oxidative stress and glucotoxicity Li, Ning; Karaca Emre, Melis; Maechler, Pierre 2017
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