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Integration of Wnt-inhibitory activity and structural novelty scoring results to uncover novel bioactive natural products : new Bicyclo[3.3.1]non-3-ene-2,9-diones from the leaves of Hymenocardia punctataFrontiers in chemistry
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2024 48 21
Germline mutations in a G protein identify signaling cross-talk in T cellsScience
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2024 112 0
Neomorphic Gαo mutations gain interaction with Ric8 proteins in GNAO1 encephalopathiesThe journal of clinical investigation
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2024 47 22
Cortical neurons obtained from patient-derived iPSCs with GNAO1 p.G203R variant show altered differentiation and functional propertiesHeliyon
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2024 146 28
Ganoderma lucidum spore oil synergistically enhances the function of cyclophosphamide in the prevention of breast cancer metastasisJournal of the Chinese Medical Association
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2024 183 55
Response to Mortimer et al. “Clinical and molecular profiling in GNAO1 permits phenotype–genotype correlation”Movement disorders
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2024 36 0
Antimicrobial Action Mechanisms of Natural Compounds Isolated from Endophytic MicroorganismsAntibiotics
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2024 58 34
Zinc for GNAO1 encephalopathy : preclinical profiling and a clinical caseMed
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2024 47 25
Challenging Reported Frizzled-Targeting Compounds in Selective Assays Reveals Lack of Functional Inhibition and Claimed ProfilesACS pharmacology & translational science
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2024 141 27
Chemical and Biological Characterization of Metabolites from Silene viridiflora Using Mass Spectrometric and Cell-Based AssaysBiomolecules
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2024 48 33
Clinical and Molecular Profiling in GNAO1 Permits Phenotype–Genotype CorrelationMovement disorders
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2024 52 51
GNAO1 Mutations Affecting the N‐Terminal α‐Helix of Gαo Lead to ParkinsonismMovement disorders
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2024 71 43
Cis-regulatory polymorphism at fiz ecdysone oxidase contributes to polygenic evolutionary response to malnutrition in DrosophilaPLOS genetics
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2024 39 29
Route to measure exact parameters of bio-nanostructures self-assemblyBiomolecules
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2024 32 50
Clinical Cases and the Molecular Profiling of a Novel Childhood Encephalopathy-Causing GNAO1 Mutation P170RCells
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2023 69 15
Humanization for neurological disease modeling: A roadmap to increase the potential of Drosophila model systemsAnimal models and experimental medicine
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2023 53 46
Wnt-Independent SARS-CoV-2 Infection in Pulmonary Epithelial CellsMicrobiology spectrum
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2023 126 49
Shallow- and deep-water Ophiura species produce a panel of chlorin compounds with potent photodynamic anticancer activitiesAntioxidants
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2023 161 37
Clofazimine: a journey of a drugBiomedicine & pharmacotherapy
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2023 60 79
In-depth molecular profiling of an intronic GNAO1 mutant as the basis for personalized high-throughput drug screeningMed
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2023 108 1
Pediatric GNAO1 encephalopathies: from molecular etiology of the disease to drug discoveryNeural Regeneration Research
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2023 77 60
Gln52 mutations in GNAO1-related disorders and personalized drug discoveryEpilepsy & behavior reports
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2023 134 26
Ganoderma lucidum extract promotes tumor cell pyroptosis and inhibits metastasis in breast cancerFood and chemical toxicology
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2023 109 2
Long cruising aptamer-albumin nanobots intelligently capture and restrain circulating tumor cellsNano today
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2023 63 0
Cells of the tumor microenvironment speak the Wnt languageTrends in molecular medicine
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2023 107 4
Improved approaches to channel capacity estimation discover compromised GPCR signaling in diverse cancer cellsiScience
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2023 66 22
Local and substrate-specific S-palmitoylation determines subcellular localization of GαoNature Communications
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2022 271 119
Gαi2-induced conductin/axin2 condensates inhibit Wnt/β-catenin signaling and suppress cancer growthNature communications
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2022 295 174
Wnt-pathway inhibitors with selective activity against triple-negative breast cancer: from thienopyrimidine to quinazoline inhibitorsFrontiers in pharmacology
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2022 160 92
Bactericidal and antiviral bionic metalized nanocoatingsNanomaterials
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2022 175 85
Chemoenzymatic synthesis of complex phenylpropanoid derivatives by the Botrytis cinerea secretome and evaluation of their wnt inhibition activityFrontiers in plant science
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2022 270 104
Chlorin endogenous to the north pacific brittle star ophiura sarsii for photodynamic therapy applications in breast cancer and glioblastoma modelsBiomedicines
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2022 438 109
Chemoenzymatic synthesis of original stilbene dimers possessing wnt inhibition activity in triple-negative breast cancer cells using the enzymatic secretome of Botrytis cinerea persFrontiers in chemistry
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2022 190 91
Restoration of the GTPase activity and cellular interactions of Gαo mutants by Zn2+ in GNAO1 encephalopathy modelsScience advances
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2022 162 126
Mouse models characterize GNAO1 encephalopathy as a neurodevelopmental disorder leading to motor anomalies: from a severe G203R to a milder C215Y mutationActa neuropathologica communications
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2022 237 102
Marine natural products from the russian pacific as sources of drugs for neurodegenerative diseasesMarine drugs
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2022 113 113
Embedding similarities between embryos and circulating tumor cells: fundamentals of abortifacients used for cancer metastasis chemopreventionJournal of experimental & clinical cancer research
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2021 169 77
Mining natural compounds to target WNT signaling: land and sea talesPharmacology of the WNT signaling system
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2021 178 1
Pediatric encephalopathy: cinical, biochemical and cellular insights into the role of Gln52 of GNAO1 and GNAI1 for the dominant diseaseCells
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2021 364 137
Knockdown of dehydrodolichyl diphosphate synthase in the drosophila retina leads to a unique pattern of retinal degenerationFrontiers in Molecular Neuroscience
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2021 154 64
A cytotoxic porphyrin from North Pacific brittle star Ophiura sarsiiMarine Drugs
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2021 461 213
Optimization of the clofazimine structure leads to a highly water-soluble C3-aminopyridinyl riminophenazine endowed with improved anti-Wnt and anti-cancer activity in vitro and in vivoEuropean Journal of Medicinal Chemistry
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2021 220 131
Unlocking the Wnt pathway: therapeutic potential of selective targeting FZD7 in cancerDrug discovery today
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2021 469 210
Light polarization by biological nanocoatingsACS Applied Materials & Interfaces
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2021 238 2
Short stature and combined immunodeficiency associated with mutations in RGS10Science Signaling
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2021 186 0
Isolation and identification of isocoumarin derivatives with specific inhibitory activity against wnt pathway and metabolome characterization of lasiodiplodia venezuelensisFrontiers in Chemistry
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2021 287 336
Macropinocytosis requires Gal-3 in a subset of patient-derived glioblastoma stem cellsCommunications Biology
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2021 297 182
NOL7 facilitates melanoma progression and metastasisSignal transduction and targeted therapy
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2021 139 44
The signaling duo CXCL12 and CXCR4: chemokine fuel for breast cancer tumorigenesisCancers
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2020 237 107
Generation of stilbene antimicrobials against multiresistant strains of Staphylococcus aureus through biotransformation by the enzymatic secretome of Botrytis cinereaJournal of Natural Products
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2020 312 291
Small molecule wnt pathway modulators from natural sources: history, state of the art and perspectivesCells
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2020 216 114
Reverse and forward engineering of Drosophila corneal nanocoatingsNature
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2020 371 1
Beyond TNBC: repositioning of clofazimine against a broad range of Wnt-dependent cancersFrontiers in Oncology
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2020 257 157
WDR74 induces nuclear β-catenin accumulation and activates Wnt-responsive genes to promote lung cancer growth and metastasisCancer Letters
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2020 390 1
Humanization of Drosophila Gαo to model GNAO1 paediatric encephalopathiesBiomedicines
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2020 270 110
HumanaFly: high-throughput transgenesis and expression of breast cancer transcripts in Drosophila eye discovers the RPS12-Wingless signaling axisScientific Reports
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2020 256 80
WDR74 modulates melanoma tumorigenesis and metastasis through the RPL5–MDM2–p53 pathwayOncogene
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2020 205 0
LDL receptor-related protein LRP6 senses nutrient levels and regulates Hippo signalingEMBO Reports
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2020 166 2
Niclosamide exerts anti-tumor activity through generation of reactive oxygen species and by suppression of Wnt/ β-catenin signaling axis in HGC-27, MKN-74 human gastric cancer cellsAsia-Pacific journal of oncology
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2020 466 157
One nanometer self-assembled aptamer-DNA dendrimers carry 350 doxorubicin: super-stability and intra-nuclear DNA comet tailChemical Engineering Journal
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2020 253 0
Targeting the Wnt signalling pathway in cancer: prospects and perilsSwiss Medical Weekly
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2019 544 291
Chemo-diversification of plant extracts using a generic bromination reaction and monitoring by metabolite profilingACS Combinational Science
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2019 367 0
A high-throughput assay pipeline for specific targeting of frizzled GPCRs in cancerMethods in Cell Biology
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2019 330 0
Towards the first targeted therapy for triple-negative breast cancer: Repositioning of clofazimine as a chemotherapy-compatible selective Wnt pathway inhibitorCancer Letters
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2019 1,107 398
Simultaneous blocking of CD47 and PD-L1 increases innate and adaptive cancer immune responses and cytokine releaseEBioMedicine
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2019 327 154
The anticancer drug discovery potential of marine invertebrates from russian pacificMarine Drugs
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2019 347 159
Information theory: new look at oncogenic signaling pathwaysTrends in Cell Biology
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2019 278 390
Dramatic dysbalancing of the Wnt pathway in breast cancersScientific Reports
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2018 284 119
Medicinal mushrooms as an attractive new source of natural compounds for future cancer therapyOncotarget
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2018 208 140
Costunolide specifically binds and inhibits thioredoxin reductase 1 to induce apoptosis in colon cancerCancer Letters
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2018 171 0
Antagonistic PCP signaling pathways in the developing Drosophila eyeScientific Reports
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2018 185 84
Versatility of Turing patterns potentiates rapid evolution in tarsal attachment microstructures of stick and leaf insects (Phasmatodea)Journal of the Royal Society. Interface
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2018 166 0
High capacity in G protein-coupled receptor signalingNature Communications
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2018 362 147
Gαo (GNAO1)encephalopathies: plasma membrane vs. Golgi functionsOncotarget
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2018 230 94
Tannins from Syzygium guineense suppress Wnt signaling and proliferation of Wnt-dependent tumors through a direct effect on secreted WntsCancer Letters
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2018 290 589
Antireflective nanocoatings for UV-sensation: the case of predatory owlfly insectsJournal of Nanobiotechnology
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2017 445 150
Bioactive Natural Products Prioritization Using Massive Multi-informational Molecular NetworksACS Chemical Biology
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2017 467 352
Arthropod corneal nanocoatings: diversity, mechanisms, and functionsFunctional surfaces in biology III : diversity of the physical phenomena
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2017 363 0
Renal Fanconi Syndrome and Hypophosphatemic Rickets in the Absence of Xenotropic and Polytropic Retroviral Receptor in the NephronJournal of the American Society of Nephrology
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2017 393 0
High-throughput targeted screening in triple-negative breast cancer cells identifies Wnt-inhibiting activities in Pacific brittle starsScientific Reports
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2017 371 189
Phosphorylation by NLK inhibits YAP‐14‐3‐3‐interactions and induces its nuclear localizationEMBO Reports
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2017 347 254
Golgi-Resident Gαo Promotes Protrusive Membrane DynamicsCell
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2017 451 434
Alternative moth-eye nanostructures: antireflective properties and composition of dimpled corneal nanocoatings in silk-moth ancestorsJournal of Nanobiotechnology
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2017 394 182
Cardamonin, a chalcone, inhibits human triple negative breast cancer cell invasiveness by downregulation of Wnt/β-catenin signaling cascades and reversal of epithelial-mesenchymal transitionBioFactors
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2017 397 646
Inhibition of Wnt signalling and breast tumour growth by the multi-purpose drug suramin through suppression of heterotrimeric G proteins and Wnt endocytosisBiochemical Journal
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2016 373 271
USP2-45 Is a Circadian Clock Output Effector Regulating Calcium Absorption at the Post-Translational LevelPLOS ONE
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2016 437 175
A Second WNT for Old Drugs: Drug Repositioning against WNT-Dependent CancersCancers
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2016 378 197
Reggie-1/Flotillin-2 regulates integrin trafficking and focal adhesion turnover via Rab11aEuropean Journal of Cell Biology
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2015 399 0
Mode of interaction of the G o subunit of heterotrimeric G proteins with the GoLoco1 motif of Drosophila Pins is determined by guanine nucleotidesBioscience Reports
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2015 297 125
Origin of order in bionanostructuresRSC Advances
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2015 360 0
Diverse set of Turing nanopatterns coat corneae across insect lineagesProceedings of the National Academy of Sciences
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2015 377 259
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