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Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
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Transcription–replication conflicts underlie sensitivity to PARP inhibitors | Nature | 2024 | 24 | 7 | |||
High-resolution mapping of mitotic DNA synthesis under conditions of replication stress in cultured cells | STAR protocols | 2023 | 22 | 43 | |||
Non-covalent SARS-CoV-2 Mpro inhibitors developed from in silico screen hits | Scientific reports | 2022 | 48 | 7 | |||
Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells | Molecular cell | 2022 | 45 | 5 | |||
RAD51 protects human cells from transcription-replication conflicts | Molecular cell | 2022 | 66 | 36 | |||
A method to sequence genomic sites of mitotic DNA synthesis in mammalian cells | Methods in enzymology | 2021 | 40 | 0 | |||
Delayed DNA break repair for genome stability | Nature cell biology | 2021 | 41 | 0 | |||
Genomic Instability Profiles at the Single Cell Level in Mouse Colorectal Cancers of Defined Genotypes | Cancers | 2021 | 47 | 27 | |||
A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells | Nature communications | 2021 | 43 | 5 | |||
A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening | iScience | 2021 | 38 | 20 | |||
Draining the FEN1s for cancer therapy | Proceedings of the National Academy of Sciences of the United States of America | 2020 | 42 | 0 | |||
High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencing | Cell Research | 2020 | 56 | 6 | |||
Remodeling Collapsed DNA Replication Forks for Cancer Development | Cancer research | 2019 | 33 | 0 | |||
Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stress | Nature | 2018 | 25 | 7 | |||
Monitoring early S-phase origin firing and replication fork movement by sequencing nascent DNA from synchronized cells | Nature protocols | 2018 | 38 | 0 | |||
The role of SMARCAL1 in replication fork stability and telomere maintenance | DNA repair | 2017 | 42 | 0 | |||
Enhanced Rate of Acquisition of Point Mutations in Mouse Intestinal Adenomas Compared to Normal Tissue | Cell reports | 2017 | 39 | 6 | |||
Increased Cell Proliferation and Gene Expression of Genes Related to Bone Remodeling, Cell Adhesion and Collagen Metabolism in the Periodontal Ligament of Unopposed Molars in Growing Rats | Frontiers in Physiology | 2017 | 482 | 221 | |||
A Model to Investigate Single-Strand DNA Responses in G1 Human Cells via a Telomere-Targeted, Nuclease-Deficient CRISPR-Cas9 System | PloS one | 2017 | 50 | 4 | |||
POLD3 is haploinsufficient for DNA replication in mice | Molecular cell | 2016 | 46 | 14 | |||
Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks | Molecular cell | 2016 | 28 | 22 | |||
Alternative lengthening of human telomeres is a conservative DNA replication process with features of break‐induced replication | EMBO reports | 2016 | 34 | 13 | |||
Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2 | EMBO molecular medicine | 2016 | 38 | 6 | |||
R‐spondin 1 and noggin facilitate expansion of resident stem cells from non‐damaged gallbladders | EMBO reports | 2016 | 44 | 4 | |||
DNA Replication Stress as a Hallmark of Cancer | Annual review of pathology | 2015 | 36 | 0 | |||
Ubiquitin-H2AX fusions render 53BP1 recruitment to DNA damage sites independent of RNF8 or RNF168 | Cell cycle | 2015 | 34 | 6 | |||
PARP inhibitors and IR join forces to strike glioblastoma-initiating cells | Cell death and differentiation | 2014 | 35 | 0 | |||
Reversal of the DNA-Binding-Induced Loop L1 Conformational Switch in an Engineered Human p53 Protein | Journal of Molecular Biology | 2014 | 25 | 9 | |||
DNA replication stress as an Achilles' heel of cancer | Oncotarget | 2014 | 25 | 0 | |||
Break-Induced Replication Repair of Damaged Forks Induces Genomic Duplications in Human Cells | Science | 2014 | 38 | 4 | |||
Conservative DNA Replication | Nature reviews. Molecular cell biology | 2014 | 22 | 0 | |||
Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer | Nature cell biology | 2013 | 26 | 0 | |||
Ultraviolet-B-mediated induction of protein-protein interactions in mammalian cells | Nature communications | 2013 | 647 | 169 | |||
A high resolution genomic portrait of bladder cancer: correlation between genomic aberrations and the DNA damage response | Oncogene | 2012 | 33 | 0 | |||
A single-nucleotide substitution mutator phenotype revealed by exome sequencing of human colon adenomas | Cancer research | 2012 | 649 | 1 | |||
Structural basis of transcriptional gene silencing mediated by Arabidopsis MOM1 | PLOS genetics | 2012 | 688 | 379 | |||
Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma | Nature genetics | 2012 | 617 | 3 | |||
The helicase domain and C-terminus of human RecQL4 facilitate replication elongation on DNA templates damaged by ionizing radiation | Carcinogenesis | 2012 | 40 | 11 | |||
Crystal Structure of a Multidomain Human p53 Tetramer Bound to the Natural CDKN1A (p21) p53-Response Element | Molecular cancer research | 2011 | 23 | 0 | |||
Studies of genomic copy number changes in human cancers reveal signatures of DNA replication stress | Molecular oncology | 2011 | 28 | 5 | |||
Genomic instability in induced stem cells | Cell death and differentiation | 2011 | 29 | 0 | |||
An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity | EMBO journal | 2011 | 623 | 378 | |||
DNA polymerases ν and θ are required for efficient immunoglobulin V gene diversification in chicken | The journal of cell biology | 2010 | 23 | 4 | |||
Genomic instability — an evolving hallmark of cancer | Nature reviews. Molecular cell biology | 2010 | 35 | 0 | |||
TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint | EMBO journal | 2010 | 23 | 0 | |||
Expression, crystallization and preliminary X-ray diffraction analysis of the CMM2 region of the Arabidopsis thaliana Morpheus' molecule 1 protein | Acta crystallographica. Section F, Structural biology and crystallization communications | 2010 | 549 | 2 | |||
Oncogene-induced senescence: the bright and dark side of the response | Current opinion in cell biology | 2010 | 32 | 0 | |||
14-3-3 Binding Sites in the Snail Protein Are Essential for Snail-Mediated Transcriptional Repression and Epithelial-Mesenchymal Differentiation | Cancer research | 2010 | 37 | 0 | |||
Cyclic olefin homopolymer-based microfluidics for protein crystallization and in situ X-ray diffraction | Acta crystallographica. Section D, Biological crystallography | 2009 | 26 | 5 | |||
Emerging common themes in regulation of PIKKs and PI3Ks | EMBO journal | 2009 | 22 | 5 | |||
Microcollimator for Micrometer-Wide Stripe Irradiation of Cells Using 20–30 keV X Rays | Radiation research | 2009 | 26 | 0 | |||
The Biochemistry Department of the University of Geneva: Understanding the Molecular Basis and Function of Intracellular Organization | Chimia | 2009 | 189 | 110 |