TH
Publications
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Title Published in Access level OA Policy Year Views Downloads
Transcription–replication conflicts underlie sensitivity to PARP inhibitorsNature
accessLevelPublic
2024 33 15
High-resolution mapping of mitotic DNA synthesis under conditions of replication stress in cultured cellsSTAR protocols
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2023 55 75
Non-covalent SARS-CoV-2 Mpro inhibitors developed from in silico screen hitsScientific reports
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2022 59 20
Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cellsMolecular cell
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2022 58 16
RAD51 protects human cells from transcription-replication conflictsMolecular cell
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2022 86 53
A method to sequence genomic sites of mitotic DNA synthesis in mammalian cellsMethods in enzymology
accessLevelRestricted
2021 51 0
Delayed DNA break repair for genome stabilityNature cell biology
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2021 49 0
Genomic Instability Profiles at the Single Cell Level in Mouse Colorectal Cancers of Defined GenotypesCancers
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2021 64 47
A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cellsNature communications
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2021 57 8
A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screeningiScience
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2021 57 39
Draining the FEN1s for cancer therapyProceedings of the National Academy of Sciences of the United States of America
accessLevelRestricted
2020 63 0
High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencingCell Research
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2020 77 14
Remodeling Collapsed DNA Replication Forks for Cancer DevelopmentCancer research
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2019 47 0
Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stressNature
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2018 41 12
Monitoring early S-phase origin firing and replication fork movement by sequencing nascent DNA from synchronized cellsNature protocols
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2018 54 0
The role of SMARCAL1 in replication fork stability and telomere maintenanceDNA repair
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2017 54 0
Enhanced Rate of Acquisition of Point Mutations in Mouse Intestinal Adenomas Compared to Normal TissueCell reports
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2017 44 11
Increased Cell Proliferation and Gene Expression of Genes Related to Bone Remodeling, Cell Adhesion and Collagen Metabolism in the Periodontal Ligament of Unopposed Molars in Growing RatsFrontiers in Physiology
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2017 501 227
A Model to Investigate Single-Strand DNA Responses in G1 Human Cells via a Telomere-Targeted, Nuclease-Deficient CRISPR-Cas9 SystemPloS one
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2017 57 6
POLD3 is haploinsufficient for DNA replication in miceMolecular cell
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2016 56 22
Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication ForksMolecular cell
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2016 38 60
Alternative lengthening of human telomeres is a conservative DNA replication process with features of break‐induced replicationEMBO reports
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2016 45 22
Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2EMBO molecular medicine
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2016 42 7
R‐spondin 1 and noggin facilitate expansion of resident stem cells from non‐damaged gallbladdersEMBO reports
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2016 58 14
DNA Replication Stress as a Hallmark of CancerAnnual review of pathology
accessLevelRestricted
2015 49 0
Ubiquitin-H2AX fusions render 53BP1 recruitment to DNA damage sites independent of RNF8 or RNF168Cell cycle
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2015 42 17
PARP inhibitors and IR join forces to strike glioblastoma-initiating cellsCell death and differentiation
accessLevelRestricted
2014 51 0
Reversal of the DNA-Binding-Induced Loop L1 Conformational Switch in an Engineered Human p53 ProteinJournal of Molecular Biology
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2014 34 20
DNA replication stress as an Achilles' heel of cancerOncotarget
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2014 33 0
Break-Induced Replication Repair of Damaged Forks Induces Genomic Duplications in Human CellsScience
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2014 55 45
Conservative DNA ReplicationNature reviews. Molecular cell biology
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2014 30 0
Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancerNature cell biology
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2013 43 0
Ultraviolet-B-mediated induction of protein-protein interactions in mammalian cellsNature communications
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2013 664 171
A high resolution genomic portrait of bladder cancer: correlation between genomic aberrations and the DNA damage responseOncogene
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2012 45 0
A single-nucleotide substitution mutator phenotype revealed by exome sequencing of human colon adenomasCancer research
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2012 665 1
Structural basis of transcriptional gene silencing mediated by Arabidopsis MOM1PLOS genetics
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2012 715 395
Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanomaNature genetics
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2012 635 3
The helicase domain and C-terminus of human RecQL4 facilitate replication elongation on DNA templates damaged by ionizing radiationCarcinogenesis
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2012 46 15
Crystal Structure of a Multidomain Human p53 Tetramer Bound to the Natural CDKN1A (p21) p53-Response ElementMolecular cancer research
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2011 30 0
Studies of genomic copy number changes in human cancers reveal signatures of DNA replication stressMolecular oncology
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2011 33 8
Genomic instability in induced stem cellsCell death and differentiation
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2011 35 0
An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificityEMBO journal
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2011 659 385
DNA polymerases ν and θ are required for efficient immunoglobulin V gene diversification in chickenThe journal of cell biology
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2010 30 6
Genomic instability — an evolving hallmark of cancerNature reviews. Molecular cell biology
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2010 47 0
TopBP1 functions with 53BP1 in the G1 DNA damage checkpointEMBO journal
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2010 33 0
Expression, crystallization and preliminary X-ray diffraction analysis of the CMM2 region of the Arabidopsis thaliana Morpheus' molecule 1 proteinActa crystallographica. Section F, Structural biology and crystallization communications
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2010 568 2
Oncogene-induced senescence: the bright and dark side of the responseCurrent opinion in cell biology
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2010 44 0
14-3-3 Binding Sites in the Snail Protein Are Essential for Snail-Mediated Transcriptional Repression and Epithelial-Mesenchymal DifferentiationCancer research
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2010 44 0
Cyclic olefin homopolymer-based microfluidics for protein crystallization and in situ X-ray diffractionActa crystallographica. Section D, Biological crystallography
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2009 33 9
Emerging common themes in regulation of PIKKs and PI3KsEMBO journal
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2009 27 7
Microcollimator for Micrometer-Wide Stripe Irradiation of Cells Using 20–30 keV X RaysRadiation research
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2009 37 0
The Biochemistry Department of the University of Geneva: Understanding the Molecular Basis and Function of Intracellular OrganizationChimia
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2009 214 123
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