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A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survivalNature communications
accessLevelPublic
2024 52 14
Multiple allelic configurations govern long-range Shh enhancer-promoter communication in the embryonic forebrainMolecular cell
accessLevelRestricted
2024 52 0
Pre-hypertrophic chondrogenic enhancer landscape of limb and axial skeleton developmentNature communications
accessLevelPublic
2024 54 20
Genetic cold cases: lessons from solving complex congenital limb disordersGenes & development
accessLevelPublic
2023 75 31
Inhibitory SMAD6 interferes with BMP dependent generation of muscle progenitor cells and perturbs proximodistal pattern of murine limb musclesDevelopment
accessLevelPublic
2023 109 34
MAZ regulates chromatin domain insulation and genome architectureNature genetics
accessLevelRestricted
2022 151 3
Context-dependent enhancer function revealed by targeted inter-TAD relocationNature communications
accessLevelPublic
2022 234 82
Non-coding deletions identify Maenli lncRNA as a limb-specific En1 regulatorNature
accessLevelRestricted
2021 283 0
Cell-specific alterations in Pitx1 regulatory landscape activation caused by the loss of a single enhancerNature communications
accessLevelPublic
2021 196 94
Preformed chromatin topology assists transcriptional robustness of Shh during limb developmentProceedings of the National Academy of Sciences
accessLevelRestricted
2019 336 0
Modeling single-molecule conformations of the HoxD region in mouse embryonic stem and cortical neuronal cellsCell Reports
accessLevelPublic
2019 353 138
Serial genomic inversions induce tissue-specific architectural stripes, gene misexpression and congenital malformationsNature Cell Biology
accessLevelRestricted
2019 391 2
Chromatin topology in development and diseaseCurrent Opinion in Genetics & Development
accessLevelPublic
2019 503 148
Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesisNature Genetics
accessLevelRestricted
2018 464 1
Polymer physics predicts the effects of structural variants on chromatin architectureNature Genetics
accessLevelRestricted
2018 455 0
Similarities and differences in the regulation of HoxD genes during chick and mouse limb developmentPLOS Biology
accessLevelPublic
2018 452 204
CRISPR/Cas9 Genome Editing in Embryonic Stem CellsMethods in Molecular Biology
accessLevelRestricted
2017 333 2
Characterization of hundreds of regulatory landscapes in developing limbs reveals two regimes of chromatin foldingGenome Research
accessLevelPublic
2017 453 242
The three-dimensional genome: regulating gene expression during pluripotency and developmentDevelopment
accessLevelPublic
2017 451 405
Integration of Shh and Fgf signaling in controlling Hox gene expression in cultured limb cellsProceedings of the National Academy of Sciences
accessLevelPublic
2017 390 163
Formation of new chromatin domains determines pathogenicity of genomic duplicationsNature
accessLevelRestricted
2016 429 0
Control of Hoxd gene transcription in the mammary bud by hijacking a preexisting regulatory landscapeProceedings of the National Academy of Sciences
accessLevelPublic
2016 382 222
Deletions, Inversions, Duplications: Engineering of Structural Variants using CRISPR/Cas in MiceCell Reports
accessLevelPublic
2015 364 255
SnapShot: Hox gene regulationCell
accessLevelRestricted
2014 327 0
Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbsNature
accessLevelRestricted
2014 420 1
A switch between topological domains underlies HoxD genes collinearity in mouse limbsScience
accessLevelRestricted
2013 384 1
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