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Temporal constraints on enhancer usage shape the regulation of limb gene transcriptionNature communications
accessLevelPublic
2026 9 5
Comparative single-cell analyses reveal evolutionary repurposing of a conserved gene programme in bat wing developmentNature ecology & evolution
accessLevelPublic
2025 13 18
Liebenberg syndrome severity arises from variations in Pitx1 locus topology and proportion of ectopically transcribing cellsNature communications
accessLevelPublic
2025 17 21
Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypesNature genetics
accessLevelPublic
2025 20 16
A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survivalNature communications
accessLevelPublic
2024 71 30
Multiple allelic configurations govern long-range Shh enhancer-promoter communication in the embryonic forebrainMolecular cell
accessLevelRestricted
2024 73 0
Pre-hypertrophic chondrogenic enhancer landscape of limb and axial skeleton developmentNature communications
accessLevelPublic
2024 81 34
Genetic cold cases: lessons from solving complex congenital limb disordersGenes & development
accessLevelPublic
2023 88 43
Inhibitory SMAD6 interferes with BMP dependent generation of muscle progenitor cells and perturbs proximodistal pattern of murine limb musclesDevelopment
accessLevelPublic
2023 140 64
MAZ regulates chromatin domain insulation and genome architectureNature genetics
accessLevelRestricted
2022 176 3
Context-dependent enhancer function revealed by targeted inter-TAD relocationNature communications
accessLevelPublic
2022 256 127
Non-coding deletions identify Maenli lncRNA as a limb-specific En1 regulatorNature
accessLevelRestricted
2021 317 0
Cell-specific alterations in Pitx1 regulatory landscape activation caused by the loss of a single enhancerNature communications
accessLevelPublic
2021 214 143
Preformed chromatin topology assists transcriptional robustness of Shh during limb developmentProceedings of the National Academy of Sciences
accessLevelRestricted
2019 354 0
Modeling single-molecule conformations of the HoxD region in mouse embryonic stem and cortical neuronal cellsCell Reports
accessLevelPublic
2019 386 150
Serial genomic inversions induce tissue-specific architectural stripes, gene misexpression and congenital malformationsNature Cell Biology
accessLevelRestricted
2019 418 2
Chromatin topology in development and diseaseCurrent Opinion in Genetics & Development
accessLevelPublic
2019 530 217
Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesisNature Genetics
accessLevelRestricted
2018 483 1
Polymer physics predicts the effects of structural variants on chromatin architectureNature Genetics
accessLevelRestricted
2018 482 0
Similarities and differences in the regulation of HoxD genes during chick and mouse limb developmentPLOS Biology
accessLevelPublic
2018 483 231
CRISPR/Cas9 Genome Editing in Embryonic Stem CellsMethods in Molecular Biology
accessLevelRestricted
2017 350 2
Characterization of hundreds of regulatory landscapes in developing limbs reveals two regimes of chromatin foldingGenome Research
accessLevelPublic
2017 470 272
The three-dimensional genome: regulating gene expression during pluripotency and developmentDevelopment
accessLevelPublic
2017 474 497
Integration of Shh and Fgf signaling in controlling Hox gene expression in cultured limb cellsProceedings of the National Academy of Sciences
accessLevelPublic
2017 406 190
Formation of new chromatin domains determines pathogenicity of genomic duplicationsNature
accessLevelRestricted
2016 463 0
Control of Hoxd gene transcription in the mammary bud by hijacking a preexisting regulatory landscapeProceedings of the National Academy of Sciences
accessLevelPublic
2016 403 299
Deletions, Inversions, Duplications: Engineering of Structural Variants using CRISPR/Cas in MiceCell Reports
accessLevelPublic
2015 400 288
SnapShot: Hox gene regulationCell
accessLevelRestricted
2014 344 0
Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbsNature
accessLevelRestricted
2014 449 1
A switch between topological domains underlies HoxD genes collinearity in mouse limbsScience
accessLevelRestricted
2013 401 1
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