2018

Scientific Articles

unige:110999	Complex Drug-Drug-Gene-Disease Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical Perspectives	Storelli, Flavia; Samer, Caroline Flora; Reny, Jean-Luc; Desmeules, Jules Alexandre; Daali, Youssef
unige:101831	Cost-effectiveness of HLA-DQB1/HLA-B pharmacogenetic-guided treatment and blood monitoring in US patients taking clozapine	Girardin, François; Poncet, Antoine; Perrier, Arnaud; Vernaz-Hegi, Nathalie; ... Villard, Jean
unige:111012	Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites	Marsousi, Niloufar; Daali, Youssef; Fontana, Pierre; Reny, Jean-Luc; ... Samer, Caroline Flora
unige:110991	Severe and persistent morphine-induced respiratory depression associated with ATP-Binding Cassette Subfamily B Member 1 and catechol-O-methyltransferase genetic defects: A case report	Aebischer, Gaspard; Ing Lorenzini, Kuntheavy; Tomala, Simon; Desmeules, Jules Alexandre; ... Samer, Caroline Flora
unige:107473	When the Safe Alternative Is Not That Safe: Tramadol Prescribing in Children	Rodieux, Frédérique; Vutskits, Laszlo; Posfay Barbe, Clara; Habre, Walid; ... Samer, Caroline Flora

2017

Scientific Articles

unige:98712	"Late" Withdrawal Syndrome after Carbamazepine In Utero Exposure in a CYP2C9 Slow Metabolizer Newborn	Passia, Evangelia; Rock, Nathalie; Pfister, Riccardo; Ing Lorenzini, Kuntheavy; ... Samer, Caroline Flora
unige:99765	Apixaban Pharmacokinetics at Steady State in Hemodialysis Patients	Mavrakanas, Thomas A; Samer, Caroline Flora; Nessim, Sharon J; Frisch, Gershon; Lipman, Mark L
unige:90072	Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferases	Romand, Stéphanie Anne; Spaggiari, Dany; Marsousi, Niloufar; Samer, Caroline Flora; ... Rudaz, Serge
unige:107400	Creation of the Swiss group of Pharmacogenomics and personalised Therapy (SPT)	Amstutz, Ursula; Mlakar, Vid; Huezo-Diaz Curtis, Patricia; Samer, Caroline Flora; ... Ansari Djaberi, Marc Georges
unige:107409	Grundlagen und praktische Hinweise fur pharmakogenetische Tests : Personalisierte Therapie bei Psychopharmaka = Notions de base et aspects pratiques à propos de tests pharmacogénétiques : pharmacogénomique et thérapie personnalisée	Baumann, Pierre; Amstutz, Ursula; Jetter, Alexander; Samer, Caroline Flora; Ansari Djaberi, Marc Georges
unige:107410	Notions de base et aspects pratiques à propos de tests pharmacogénétiques : pharmacogénomique et thérapie personnalisée = Grundlagen und praktische Hinweise für pharmakogenetische Tests : Personalisierte Therapie bei Psychopharmaka	Baumann, Pierre; Amstutz, ursula; Jetter, Alexander; Samer, Caroline Flora; Ansari Djaberi, Marc Georges
unige:99763	Pharmacogénomique et thérapie personnalisée	Baumann, Pierre-Pascal; Amstutz, Ursula; Bühlmann, Roland P; Meier-Abt, Peter; ... Ansari Djaberi, Marc Georges
unige:98702	PIM-Check: development of an international prescription-screening checklist designed by a Delphi method for internal medicine patients	Desnoyer, Aude; Blanc, Anne-Laure; Pourcher, Valérie; Besson, Marie; ... Guignard, Bertrand
unige:86303	Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective study	Lloret-Linares, Célia; Rollason Gumprecht, Victoria; Ing Lorenzini, Kuntheavy; Samer, Caroline Flora; ... Besson, Marie

Privat-docent Thesis

unige:94125

Cytochromes P450 activity and functionality: biomarker of drug response and valuable tool for Precision Medicine

Samer, Caroline Flora;

2016

Scientific Articles

unige:86304	Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approach	Marsousi, Niloufar; Samer, Caroline Flora; Fontana, Pierre; Reny, Jean-Luc; ... Daali, Youssef
unige:86308	Evaluation of Mutual Drug-Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method	Bosilkovska Weisskopf, Marija; Samer, Caroline Flora; Deglon, Julien; Thomas, Aurélien; ... Daali, Youssef
unige:89764	HIV-Positive-to-HIV-Positive Liver Transplantation	Calmy, Alexandra; Van Delden, Christian; Giostra, Emiliano; Junet, C; ... Berney, Thierry
unige:85403	Letter by Bouatou et al Regarding Article, "Polypharmacy and the Efficacy and Safety of Rivaroxaban Versus Warfarin in the Prevention of Stroke in Patients With Nonvalvular Atrial Fibrillation"	Bouatou, Yassine; El Biali, Myriam; Samer, Caroline Flora;
unige:93800	Rivaroxaban-Induced Hemorrhage Associated with ABCB1 Genetic Defect	Ing Lorenzini, Kuntheavy; Daali, Youssef; Fontana, Pierre; Desmeules, Jules Alexandre; Samer, Caroline Flora
unige:99764	Une histoire qui ne manque pas de mordant	Amstutz, Cédric; Samer, Caroline Flora; Plan, Pierre-Alain;

2015

Scientific Articles

unige:89815	Corrigendum to "Dolutegravir-based antiretroviral therapy in a severely overweight child with a multi-drug resistant human immunodeficiency virus infection. A case report and review" [New Microbes New Infect] 6 (2015) 1-4]	Wagner, Noémie; Wyler, Claire-Anne; Yerly Ferrillo, Sabine; Samer, Caroline Flora; ... Ambrosioni Czyrko, Juan
unige:74012	Direct oral anticoagulants: efficacy and safety in patient subgroups	Mavrakanas, Thomas; Samer, Caroline Flora; Fontana, Pierre; Perrier, Arnaud;
unige:76220	Dolutegravir-based antiretroviral therapy in a severely overweight child with a multidrug-resistant human immunodeficiency virus infection. A case report and review	Wagner, Noémie; Wyler, Claire-Anne; Yerly Ferrillo, Sabine; Samer, Caroline Flora; ... Ambrosioni Czyrko, Juan
unige:78721	Drug-related problems identification in general internal medicine: The impact and role of the clinical pharmacist and pharmacologist	Guignard, Bertrand; Bonnabry, Pascal; Perrier, Arnaud; Dayer, Pierre; ... Samer, Caroline Flora
unige:74755	Evidence-Based Choice of P2Y12 Inhibitors in End Stage Renal Disease Patients: A Mini-Review	Bouatou, Yassine; Samer, Caroline Flora; Fontana, Pierre; Daali, Youssef; Desmeules, Jules Alexandre
unige:78720	Providing Quality Therapeutics in Switzerland: Role of the Stakeholders and Recent Incentives for Further Improvements	Besson, Marie; Samer, Caroline Flora; Rollason Gumprecht, Victoria; Dayer, Pierre; Desmeules, Jules Alexandre

2014

Scientific Articles

unige:36848	Geneva Cocktail for Cytochrome P450 and P-glycoprotein Activity Assessment Using Dried Blood Spots	Bosilkovska Weisskopf, Marija; Samer, Caroline Flora; Deglon, Julien; Rebsamen, Michela; ... Daali, Youssef
unige:38282	Prediction by pharmacogenetics of safety and efficacy of non-steroidal anti- inflammatory drugs: a review	Rollason Gumprecht, Victoria; Samer, Caroline Flora; Daali, Youssef; Desmeules, Jules Alexandre;
unige:54963	Prediction of Metabolic Interactions With Oxycodone via CYP2D6 and CYP3A Inhibition Using a Physiologically Based Pharmacokinetic Model	Marsousi, Niloufar; Daali, Youssef; Rudaz, Serge; Almond, L; ... Samer, Caroline Flora
unige:43679	Simultaneous LC-MS/MS quantification of P-glycoprotein and cytochrome P450 probe substrates and their metabolites in DBS and plasma	Bosilkovska Weisskopf, Marija; Deglon, Julien; Samer, Caroline Flora; Walder, Bernhard; ... Daali, Youssef
unige:43677	Therapeutic drug monitoring of voriconazole: a case report of multiple drug interactions in a patient with an increased CYP2C19 activity	Bouatou, Yassine; Samer, Caroline Flora; Ing Lorenzini, Kuntheavy Roseline; Daali, Youssef; ... Escher, Monica

2013

Scientific Articles

unige:27792	Applications of CYP450 Testing in the Clinical Setting	Samer, Caroline Flora; Ing Lorenzini, Kuntheavy; Rollason Gumprecht, Victoria; Daali, Youssef; Desmeules, Jules Alexandre
unige:90157	Carbimazole-induced, ANCA-associated, crescentic glomerulonephritis: case report and literature review	Mavrakanas, Thomas A; Bouatou, Yassine; Samer, Caroline Flora; De Seigneux Matthey, Sophie; Meyer, Patrick
unige:99750	Clinical Course and Management of Iatrogenic Cushing’s Syndrome after Co-Administration of Injected-Triamcinolone and Ritonavir: a Systematic Review	John, Gregor Raphaël; Ollo, Diana; Meyer, Patrick; Herold, Markus; ... Calmy, Alexandra
unige:90155	Hepatic fat loss in advanced nonalcoholic steatohepatitis: are alterations in serum adiponectin the cause?	van der Poorten, David; Samer, Caroline Flora; Ramezani-Moghadam, Mehdi; Coulter, Sally; ... George, Jacob
unige:33236	Human urinary biomarkers of dioxin exposure: Analysis by metabolomics and biologically driven data dimensionality reduction	Jeanneret, Fabienne; Boccard, Julien; Badoud, Flavia; Sorg, Olivier; ... Rudaz, Serge
unige:27159	Pharmacokinetic interaction between prasugrel and ritonavir in healthy volunteers	Ancrenaz, Virginie; Deglon, Julien; Samer, Caroline Flora; Staub, Christian Olivier; ... Desmeules, Jules Alexandre
unige:90406	Pulmonary embolism and iatrogenic Cushing's syndrome after co-administration of injected-triamcinolone and ritonavir	John, Gregor Raphaël; Ollo, Diana; Meyer, Patrick; Samer, Caroline Flora; Calmy, Alexandra
unige:33753	Traiter efficacement la douleur incidente chez l'adulte. Donnez le bon antalgique au bon moment	Berna, Chantal; Luthy, Christophe Samuel; Samer, Caroline Flora; Spechbach, Hervé; ... Piguet, Valérie

2012

Scientific Articles

unige:19333	Oral flurbiprofen metabolic ratio assessment using a single-point dried blood spot	Daali, Youssef; Samer, Caroline Flora; Deglon, Julien; Thomas, Aurélien; ... Desmeules, Jules Alexandre
unige:27154	Quel programme informatique de détection des interactions médicamenteuses néfastes ?	Ing Lorenzini, Kuntheavy; Reutemann, Barbara; Samer, Caroline Flora; Guignard, Bertrand; ... Desmeules, Jules Alexandre
unige:27156	Serotonin syndrome following drug-drug interactions and CYP2D6 and CYP2C19 genetic polymorphisms in an HIV-infected patient	Lorenzini, Kuntheavy I.; Calmy, Alexandra; Ambrosioni Czyrko, Juan; Assouline, Benjamin; ... Samer, Caroline Flora

2011

Scientific Articles

unige:42027	Automated system for on-line desorption of dried blood spots applied to LC/MS/MS pharmacokinetic study of flurbiprofen and its metabolite	Deglon, Julien; Thomas, Aurélien; Daali, Youssef; Lauer, Estelle; ... Staub, Christian
unige:92715	Moving towards dose individualization of tyrosine kinase inhibitors	Klümpen, Heinz-Josef; Samer, Caroline Flora; Mathijssen, Ron H J; Schellens, Jan H M; Gurney, Howard

2010

Scientific Articles

unige:21282	Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety	Samer, Caroline Flora; Daali, Youssef; Wagner, M.; Hopfgartner, Gerard; ... Desmeules, Jules Alexandre
unige:20425	Impact of genetic polymorphisms and drug-drug interactions on clopidogrel and prasugrel response variability	Ancrenaz, Virginie; Daali, Youssef; Fontana, Pierre; Besson, M.; ... Desmeules, Jules Alexandre
unige:20440	Réactions d'hypersensibilité immédiates aux anti-inflammatoires non stéroïdiens: allergie ou pseudo-allergie?	Brandstätter, Hilda; Samer, Caroline Flora; Ribi, Camillo; Piguet, Valérie;
unige:21283	The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone	Samer, Caroline Flora; Daali, Youssef; Wagner, M.; Hopfgartner, Gerard; ... Desmeules, Jules Alexandre

2008

Scientific Articles

unige:19003

Pharmacogenetics of analgesics: toward the individualization of prescription

Rollason, Victoria; Samer, Caroline Flora; Piguet, Valérie; Dayer, Pierre; Desmeules, Jules Alexandre