2014

Scientific Articles

unige:40568	cIEF for rapid pKa determination of small molecules: A proof of concept	Romand, Stéphanie Anne; Schappler, Julie; Veuthey, Jean-Luc; Carrupt, Pierre-Alain; Martel, Sophie
unige:46356	Predicting both passive intestinal absorption and the dissociation constant toward albumin using the PAMPA technique	Bujard, Alban; Sol, Marine; Carrupt, Pierre-Alain; Martel, Sophie;

2013

Scientific Articles

unige:28608	Large, chemically diverse dataset of logP measurements for benchmarking studies	Martel, Sophie; Gillerat, Fabrice; Carosati, E.; Maiarelli, D.; ... Carrupt, Pierre-Alain
unige:97047	New high throughput screening method for drug release measurements	Pelczarska, Aleksandra Paulina; Delie Salmon, Florence; Domańska, Urszula; Carrupt, Pierre-Alain; Martel, Sophie

2012

Scientific Articles

unige:19413

Synthesis physicochemical profile and PAMPA study of new NO-donor edaravone co-drugs

Rolando, Barbara; Filieri, Andrea; Chegaev, Konstantin; Lazzarato, Loretta; ... Gasco, Alberto

2011

Scientific Articles

unige:17531

Biarylmethoxy isonipecotanilides as potent and selctive inhibitors of blood coagulation facture Xa

Lopoplo, G.; Fiorella, F.; de Candia, M.; Nicoletti, O.; ... Altomare, C.

2010

Scientific Articles

unige:6344	Advances in LC platforms for drug discovery	Nicoli, Raul; Martel, Sophie; Rudaz, Serge; Wolfender, Jean-Luc; ... Guillarme, Davy
unige:11802	Drug-protein binding: a critical review of analytical tools	Vuignier, Karine; Schappler, Julie; Veuthey, Jean-Luc; Carrupt, Pierre-Alain; Martel, Sophie
unige:11035	Improvement of a capillary electrophoresis/frontal analysis (CE/FA) method for determining binding constants: Discussion on relevant parameters	Vuignier, Karine; Schappler, Julie; Veuthey, Jean-Luc; Carrupt, Pierre-Alain; Martel, Sophie
unige:14543	In vitro blood brain barrier models as a screening tool for colloidal drug delivery systems and other nanosystems	Garcel, Aude; Martel, Sophie; Carrupt, Pierre-Alain; Doelker, Eric; Delie Salmon, Florence
unige:10644	Physicochemical profile and in vitro permeation behavior of a new class of non-steroidal anti-inflammatory drug candidates	Rolando, B.; Lazzarato, L.; Di Stilo, A.; Fruttero, Roberta; ... Gasco, Alberto

2009

Scientific Articles

unige:1631	Analytical tools for the physicochemical profiling of drug candidates to predict absorption/distribution	Henchoz, Yveline; Bard, Bruno; Guillarme, Davy; Carrupt, Pierre-Alain; ... Martel, Sophie
unige:2356	Fast log P determination by ultra-high-pressure liquid chromatography coupled with UV and mass spectrometry detections	Henchoz, Yveline; Guillarme, Davy; Martel, Sophie; Rudaz, Serge; ... Carrupt, Pierre-Alain
unige:4718	Lipophilicity determination of highly lipophilic compounds by liquid chromatography	Guillot, Amandine; Henchoz, Yveline; Moccand, Cyril; Guillarme, Davy; ... Martel, Sophie
unige:3981	Lipophilicity of basic drugs measured by hydrophilic interaction chromatography	Bard, Bruno; Carrupt, Pierre-Alain; Martel, Sophie;
unige:9930	Rapid log P determination of natural products in crude plant extracts from UHPLC-TOF-MS profiling data - an additional parameter for dereplication and bioavailability	Eugster, Philippe; Martel, Sophie; Guillarme, Davy; Carrupt, Pierre-Alain; Wolfender, Jean-Luc

Book Chapters

unige:4129

In silico tools and in vitro HTS approaches to determine lipophilicity during the drug discovery process

Martel, Sophie; Gasparik, Vincent; Carrupt, Pierre-Alain;

2008

Scientific Articles

unige:4068	High throughput UV method for the estimation of thermodynamic solubility and the determination of the solubility in biorelevant media	Bard, Bruno; Martel, Sophie; Carrupt, Pierre-Alain;
unige:1242	Isolation and quantification by high-performance liquid chromatography-ion-trap mass spectrometry of androgen sulfoconjugates in human urine	Strahm, Emmanuel; Kohler, Isabelle; Rudaz, Serge; Martel, Sophie; ... Saudan, Christophe
unige:4004	Physicochemical Profiling of Sartans: Detailed Study of Ionisation Constants and Distribution Coefficients	Tosco, Paolo; Rolando, Barbara; Fruttero, Roberta; Henchoz, Yveline; ... Gasco, Alberto
unige:4081	The PAMPA technique as a HTS tool for partition coefficients determination in different solvent/water systems	Ottaviani, Giorgio; Martel, Sophie; Escarala, Caroline; Nicolle, Edwige; Carrupt, Pierre-Alain

Book Chapters

unige:14365

Chromatographic approaches for measuring log P

Martel, Sophie; Guillarme, Davy; Henchoz, Yveline; Galland, Alexandra; ... Carrupt, Pierre-Alain

2007

Scientific Articles

unige:10623

In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities

Ottaviani, G.; Martel, Sophie; Carrupt, Pierre-Alain;

2006

Scientific Articles

unige:10622

Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability

Ottaviani, G.; Martel, Sophie; Carrupt, Pierre-Alain;

2005

Scientific Articles

unige:9947	Experimental and virtual physicochemical and pharmacokinetic profiling of new chemical entities	Martel, Sophie; Castella, M. E.; Bajot, F.; Ottaviani, G.; ... Carrupt, Pierre-Alain
unige:10535	Influence of lipophilicity and stereochemistry at the C-7 position on the cardioprotective and antioxidant effect of ginkgolides during rat heart ischemia and reperfusion	Billottet, L.; Martel, Sophie; Culcasi, M.; Drieu, K.; ... Pietri, S.
unige:9964	The medicinal chemist's dream: Faster design of better and safer drug candidates	Reist, Marianne; Novaroli, L.; Daina, Antoine; Martel, Sophie; Carrupt, Pierre-Alain