2019

Scientific Articles

unige:134650

Liquid Chromatography-Tandem Mass Spectrometry Method for Ticagrelor and its Active Metabolite Determination in Human Plasma: Application to a Pharmacokinetic Study

Marsousi, Niloufar; Rudaz, Serge; Desmeules, Jules Alexandre; Daali, Youssef;

2018

Scientific Articles

unige:111012	Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites	Marsousi, Niloufar; Daali, Youssef; Fontana, Pierre; Reny, Jean-Luc; ... Samer, Caroline Flora
unige:98710	Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software	Marsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef;

2017

Scientific Articles

unige:90072	Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferases	Romand, Stéphanie Anne; Spaggiari, Dany; Marsousi, Niloufar; Samer, Caroline Flora; ... Rudaz, Serge
unige:97051	Usefulness of PBPK Modeling in Incorporation of Clinical Conditions in Personalized Medicine	Marsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef;
unige:98706	Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future	Darwich, A S; Ogungbenro, K; Vinks, A A; Powell, J R; ... Rostami-Hodjegan, A

Doctoral Thesis

unige:100121

CYP450-mediated drug-drug interactions: towards prediction and informed dose recommendation using physiologically-based pharmacokinetic (PBPK) modeling

Marsousi, Niloufar;

2016

Scientific Articles

unige:86304	Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approach	Marsousi, Niloufar; Samer, Caroline Flora; Fontana, Pierre; Reny, Jean-Luc; ... Daali, Youssef
unige:86301	Intestinal permeability and P-glycoprotein-mediated efflux transport of ticagrelor in Caco-2 monolayer cells	Marsousi, Niloufar; Doffey-Lazeyras, Fabienne; Rudaz, Serge; Desmeules, Jules Alexandre; Daali, Youssef

2014

Scientific Articles

unige:54963

Prediction of Metabolic Interactions With Oxycodone via CYP2D6 and CYP3A Inhibition Using a Physiologically Based Pharmacokinetic Model

Marsousi, Niloufar; Daali, Youssef; Rudaz, Serge; Almond, L; ... Samer, Caroline Flora