2018

Scientific Articles

unige:105764	Expression of the DNA-Binding Factor TOX Promotes the Encephalitogenic Potential of Microbe-Induced Autoreactive CD8+ T Cells	Page, Nicolas; Klimek, Bogna; De Roo, Mathias; Steinbach, Karin; ... Merkler, Doron
unige:108173	Functional Gut Microbiota Remodeling Contributes to the Caloric Restriction-Induced Metabolic Improvements	Fabbiano, Salvatore; Suarez Zamorano, Nicolas; Chevalier, Claire; Lazarević, Vladimir; ... Trajkovski, Mirko
unige:105129	High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease	Mrdjen, Dunja; Pavlovic, Anto; Hartmann, Felix J; Schreiner, Bettina; ... Becher, Burkhard
unige:105761	Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner	Datta, Moumita; Staszewski, Ori; Raschi, Elena; Frosch, Maximilian; ... Prinz, Marco
unige:107292	Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping	Di Liberto, Giovanni; Pantelyushin, Stanislav; Kreutzfeldt, Mario; Page, Nicolas; ... Merkler, Doron

2017

Scientific Articles

unige:98402	Clival chordoma: a single-centre outcome analysis	Jaegersberg, Max; El Rahal, Amir Mohamed; Dammann, Philipp; Merkler, Doron; ... Schaller, Karl Lothard
unige:98395	Germline PMS2 and somatic POLEexo mutations cause hypermutability of the leading DNA strand in Biallelic Mismatch Repair Deficiency syndrome brain tumors	Andrianova, Maria A; Chetan, Ghati Kasturirangan; Sibin, Madathan Kandi; Mckee, Thomas Alexander; ... Nikolaev, Sergey Igorievich
unige:98396	Increased interleukin-27 cytokine expression in the central nervous system of multiple sclerosis patients	Lalive d'Epinay, Patrice; Kreutzfeldt, Mario; Devergne, Odile; Metz, Imke; ... Pot, Caroline
unige:98394	Interferon-γ-Driven iNOS: A Molecular Pathway to Terminal Shock in Arenavirus Hemorrhagic Fever	Remy, Mélissa; Sahin, Mehmet; Flatz, Lukas Roland; Regen, Tommy; ... Pinschewer, Daniel
unige:98397	Replicating viral vector platform exploits alarmin signals for potent CD8(+) T cell-mediated tumour immunotherapy	Kallert, Sandra M; Darbre, Stéphanie; Bonilla, Weldy V; Kreutzfeldt, Mario; ... Pinschewer, Daniel
unige:100197	STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells	Nunes-Hasler, Paula; Maschalidi, Sophia; Lippens, Carla; Castelbou, Cyril; ... Demaurex, Nicolas
unige:101824	The Immune System Bridges the Gut Microbiota with Systemic Energy Homeostasis: Focus on TLRs, Mucosal Barrier, and SCFAs	Spiljar, Martina; Merkler, Doron; Trajkovski, Mirko;

2016

Scientific Articles

unige:89091	B cell-derived transforming growth factor-β1 expression limits the induction phase of autoimmune neuroinflammation	Bjarnadottir, Kristbjorg; Benkhoucha, Mahdia; Merkler, Doron; Weber, Martin S; ... Lalive d'Epinay, Patrice
unige:86049	Brain-resident memory T cells represent an autonomous cytotoxic barrier to viral infection	Steinbach, Karin; Vincenti, Ilena; Kreutzfeldt, Mario; Page, Nicolas; ... Merkler, Doron
unige:88584	In vivo imaging reveals rapid astrocyte depletion and axon damage in a model of neuromyelitis optica-related pathology	Herwerth, Marina; Kalluri, Sudhakar Reddy; Srivastava, Rajneesh; Kleele, Tatjana; ... Hemmer, Bernhard
unige:94180	Interferon-driven deletion of antiviral B cells at the onset of chronic infection	Fallet, Benedict; Narr, Kerstin; Ertuna, Yusuf I; Remy, Mélissa; ... Pinschewer, Daniel
unige:84462	Macroautophagy Proteins Control MHC Class I Levels on Dendritic Cells and Shape Anti-viral CD8(+) T Cell Responses	Loi, Monica; Müller, Anne; Steinbach, Karin; Niven, Jennifer; ... Gannagé, Monique
unige:96653	Medulloblastoma in children and adults: one distinct disease entity?	Von Bueren, André; Ares Molina, Carmen; Bartoli, Andréa; Fluss, Joel Victor; ... Ansari Djaberi, Marc Georges
unige:94181	Myelinosome formation represents an early stage of oligodendrocyte damage in multiple sclerosis and its animal model	Romanelli, Elisa; Merkler, Doron; Mezydlo, Aleksandra; Weil, Marie-Theres; ... Kerschensteiner, Martin
unige:77875	pDC therapy induces recovery from EAE by recruiting endogenous pDC to sites of CNS inflammation	Duraes, Fernanda V; Lippens, Carla; Steinbach, Karin; Dubrot Armendariz, Juan; ... Hugues, Stéphanie
unige:94182	pMHC affinity controls duration of CD8+ T cell-DC interactions and imprints timing of effector differentiation versus expansion	Ozga, Aleksandra J; Moalli, Federica; Abe, Jun; Swoger, Jim; ... Koritzinsky, Marianne
unige:79115	Reconstruction of single cortical projection neurons reveals primary spine loss in multiple sclerosis	Jürgens, Tanja; Jafari, Mehrnoosh; Kreutzfeldt, Mario; Bahn, Erik; ... Merkler, Doron
unige:88585	TGFβ regulates persistent neuroinflammation by controlling Th1 polarization and ROS production via monocyte-derived dendritic cells	Parsa, Roham; Lund, Harald; Tosevski, Ivana; Zhang, Xing-Mei; ... Harris, Robert A

Thesis supervisions

unige:86373

La nucléoprotéine est nécessaire à l'immunogénicité des vecteurs vaccinaux basés sur les virus de la chorioméningite lymphocytaire recombinants (rLCMV)

Darbre, Stéphanie;

2015

Scientific Articles

unige:77899	IL-27 Induces Th17 Differentiation in the Absence of STAT1 Signaling	Peters, Anneli; Fowler, Kevin D; Chalmin, Fanny; Merkler, Doron; ... Pot, Caroline
unige:45174	Oxysterols regulate encephalitogenic CD4+ T cell trafficking during central nervous system autoimmunity	Chalmin, Fanny; Rochemont, Viviane; Lippens, Carla; Clottu, Aurélie Sarah; ... Pot, Caroline
unige:84085	Recurrent multiple CNS hemangioblastomas with VHL disease treated with pazopanib: a case report and literature review	Migliorini, Denis; Haller, Sven; Merkler, Doron; Pugliesi-Rinaldi, Angela; ... Dietrich, Pierre-Yves
unige:79114	Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage	Bhattacharya, Anannya; Hegazy, Ahmed N; Deigendesch, Nikolaus; Kosack, Lindsay; ... Bergthaler, Andréas
unige:44170	The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection	Schliehe, Christopher; Flynn, Elizabeth K; Vilagos, Bojan; Richson, Udochuku; ... Bergthaler, Andréas
unige:73892	USP18 lack in microglia causes destructive interferonopathy of the mouse brain	Goldmann, Tobias; Zeller, Nicolas; Raasch, Jenni; Kierdorf, Katrin; ... Prinz, Marco

2014

Scientific Articles

unige:42844	Hepatocyte growth factor limits autoimmune neuroinflammation via glucocorticoid-induced leucine zipper expression in dendritic cells	Benkhoucha, Mahdia; Molnarfi, Nicolas; Dunand-Sauthier, Isabelle; Merkler, Doron; ... Lalive d'Epinay, Patrice
unige:39266	Immunological mechanism of action and clinical profile of disease-modifying treatments in multiple sclerosis	Du Pasquier, Renaud A.; Pinschewer, Daniel; Merkler, Doron;
unige:36221	Myelin Membrane Wrapping of CNS Axons by PI(3,4,5)P3-Dependent Polarized Growth at the Inner Tongue	Snaidero, Nicolas; Möbius, Wiebke; Czopka, Tim; Hekking, Liesbeth H.P.; ... Simons, Mikael
unige:45633	Neuropathological Techniques to Investigate CNS Pathology in Experimental Autoimmune Encephalomyelitis (EAE)	Steinbach, Karin; Merkler, Doron;
unige:36222	Oligodendroglia in cortical multiple sclerosis lesions decrease with disease progression, but regenerate after repeated experimental demyelination	Rodriguez, Enrique Garea; Wegner, Christiane; Kreutzfeldt, Mario; Neid, Katharina; ... Merkler, Doron
unige:44378	Pervasive Axonal Transport Deficits in Multiple Sclerosis Models	Sorbara, Catherine Diamante; Wagner, Naomi Elizabeth; Ladwig, Anne; Nikić, Ivana; ... Kerschensteiner, Martin
unige:33448	TLR7 signaling exacerbates CNS autoimmunity through downregulation of Foxp3(+) Treg cells	Lalive, PH; Benkhoucha, Mahdia; Tran, Ngoc Lan; Kreutzfeldt, Mario; ... Santiago-Raber, Marie-Laure

2013

Scientific Articles

unige:33446	Infection of type I interferon receptor-deficient mice with various old world arenaviruses: a model for studying virulence and host species barriers	Rieger, Toni; Merkler, Doron; Günther, Stephan;
unige:28452	Intracranial hypertension following highly active antiretroviral therapy interruption in an HIV-infected woman: case report and review of the literature	Daou, Samira; Ambrosioni Czyrko, Juan; Merkler, Doron; Calmy, Alexandra;
unige:28454	Magnetic resonance imaging reveals therapeutic effects of interferon-beta on cytokine-induced reactivation of rat model of multiple sclerosis	Serres, Sébastien; Bristow, Claire; de Pablos, Rocío M; Merkler, Doron; ... Anthony, Daniel C
unige:28444	Neuroaxonal regeneration is more pronounced in early multiple sclerosis than in traumatic brain injury lesions	Schirmer, Lucas; Merkler, Doron; König, Fatima B; Brück, Wolfgang; Stadelmann, Christine
unige:33447	Neuroprotective intervention by interferon-γ blockade prevents CD8+ T cell-mediated dendrite and synapse loss	Kreutzfeldt, Mario; Bergthaler, Andréas; Fernandez, Marylise; Brück, Wolfgang; ... Merkler, Doron

2012

Scientific Articles

unige:28448	Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection	Enouz, Sarah; Carrié, Lucie; Merkler, Doron; Bevan, Michael J; Zehn, Dietmar
unige:28430	Endogenous ciliary neurotrophic factor modulates anxiety and depressive-like behavior	Peruga, Isabella; Hartwig, Silvia; Merkler, Doron; Thöne, Jan; ... Linker, Ralf A
unige:28443	Focal immune-mediated white matter demyelination reveals an age-associated increase in axonal vulnerability and decreased remyelination efficiency	Hampton, David W; Innes, Neill; Merkler, Doron; Zhao, Chao; ... Chandran, Siddharthan
unige:28447	IgG glycan hydrolysis by EndoS inhibits experimental autoimmune encephalomyelitis	Benkhoucha, Mahdia; Molnarfi, Nicolas; Santiago-Raber, Marie-Laure; Weber, Martin S; ... Lalive d'Epinay, Patrice
unige:28432	Late motor decline after accomplished remyelination: impact for progressive multiple sclerosis	Manrique-Hoyos, Natalia; Grønborg, Mads; Kreutzfeldt, Mario; Schedensack, Mariann; ... Jürgens, Tanja
unige:28431	The alarmin interleukin-33 drives protective antiviral CD8+ T cell responses	Bonilla, Weldy V; Fröhlich, Anja; Senn, Karin; Kallert, Sandra; ... Pinschewer, Daniel
unige:28445	Toll-like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia	Scheffel, Jörg; Regen, Tommy; Van Rossum, Denise; Seifert, Stefanie; ... Hanisch, Uwe-Karsten
unige:28450	TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis	Schattling, Benjamin; Steinbach, Karin; Thies, Edda; Kruse, Martin; ... Friese, Manuel A