2020

Scientific Articles

unige:131894	Chronic viral infection promotes efficient germinal center B cell responses	Fallet, Bénédict; Hao, Yi; Florova, Marianna; Cornille, Karen; ... Pinschewer, Daniel D
unige:131892	Microglial A20 protects the brain from CD8 T-cell-mediated immunopathology	Mohebiany, Alma Nazlie; Ramphal, Nishada Shakunty; Karram, Khalad; Di Liberto, Giovanni; ... Waisman, Ari

2019

Scientific Articles

unige:122799	Bassoon proteinopathy drives neurodegeneration in multiple sclerosis	Schattling, Benjamin; Engler, Jan Broder; Volkmann, Constantin; Rothammer, Nicola; ... Friese, Manuel A
unige:122543	Brain-resident memory T cells generated early in life predispose to autoimmune disease in mice	Steinbach, Karin; Vincenti, Ilena; Egervari, Kristof Levente; Kreutzfeldt, Mario; ... Merkler, Doron
unige:122877	CD8+ T cells induce cachexia during chronic viral infection	Baazim, Hatoon; Schweiger, Martina; Moschinger, Michael; Xu, Haifeng; ... Bergthaler, Andreas
unige:130024	Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity	Fecher, Caroline; Trovò, Laura; Müller, Stephan A; Snaidero, Nicolas; ... Misgeld, Thomas
unige:122892	Dendritic cell accumulation in the gut and central nervous system is differentially dependent on α4 integrins	Sie, Christopher; Perez, Laura Garcia; Kreutzfeldt, Mario; Potthast, Maria; ... Korn, Thomas
unige:127697	Expression of the DNA-binding factor TOX promotes the encephalitogenic potential of microbe-induced autoreactive CD8+ T cells	Page, Nicolas; Klimek, Bogna; De Roo, Mathias; Steinbach, Karin; ... Merkler, Doron
unige:122879	Fulminant multifocal relapse in a fingolimod-treated multiple sclerosis patient	Breville, Gauthier; Lascano, Agustina Maria; Merkler, Doron; Roth, Serge; Lalive d'Epinay, Patrice
unige:130025	In vivo function of the lipid raft protein flotillin-1 during CD8+ T cell-mediated host surveillance	Ficht, Xenia; Ruef, Nora; Stolp, Bettina; Samson, Guerric P B; ... Stein, Jens V
unige:130027	Initial viral inoculum determines kinapse-and synapse-like T cell motility in reactive lymph nodes	Sivapatham, Sujana; Ficht, Xenia; Barreto de Albuquerque, Juliana; Page, Nicolas; ... Stein, Jens V
unige:122779	Melanocytic colonization of choroid plexus papilloma: a previously undocumented source of pigment storage in the plexogenic epithelium	Egervari, Kristof Levente; Lobrinus, Johannes Alexander; Merkler, Doron; Vajtai, Istvan;
unige:120077	Phase I/II trial testing safety and immunogenicity of the multipeptide IMA950/poly-ICLC vaccine in newly diagnosed adult malignant astrocytoma patients	Migliorini, Denis; Dutoit Vallotton, Valérie; Allard, Mathilde Camille; Grandjean Hallez, Nicole; ... Dietrich, Pierre-Yves
unige:122794	TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection	Alfei, Francesca; Kanev, Kristiyan; Hofmann, Maike; Wu, Ming; ... Zehn, Dietmar

Thesis supervisions

unige:131624	In vivo RNA interference screening to explore T cell behaviour in neuroinflammation	Klimek, Bogna;
unige:118261	Synaptic stripping in CD8+ T cell mediated encephalitis	Di Liberto, Giovanni;

2018

Scientific Articles

unige:109372	Concurrent IDH1 and SMARCB1 Mutations in Pediatric Medulloblastoma: A Case Report	El-Ayadi, Moatasem; Egervari, Kristof Levente; Merkler, Doron; Mckee, Thomas Alexander; ... Von Bueren, André
unige:109366	Enhanced Voluntary Exercise Improves Functional Recovery following Spinal Cord Injury by Impacting the Local Neuroglial Injury Response and Supporting the Rewiring of Supraspinal Circuits	Loy, Kristina; Schmalz, Anja; Hoche, Tobias; Jacobi, Anne; ... Bareyre, Florence M
unige:105764	Expression of the DNA-binding factor TOX promotes the encephalitogenic potential of microbe-induced autoreactive CD8+ T cells	Page, Nicolas; Klimek, Bogna; De Roo, Mathias; Steinbach, Karin; ... Merkler, Doron
unige:108173	Functional Gut Microbiota Remodeling Contributes to the Caloric Restriction-Induced Metabolic Improvements	Fabbiano, Salvatore; Suarez Zamorano, Nicolas; Chevalier, Claire; Lazarevic, Vladimir; ... Trajkovski, Mirko
unige:105129	High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease	Mrdjen, Dunja; Pavlovic, Anto; Hartmann, Felix J; Schreiner, Bettina; ... Becher, Burkhard
unige:105761	Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner	Datta, Moumita; Staszewski, Ori; Raschi, Elena; Frosch, Maximilian; ... Prinz, Marco
unige:115499	Myeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunity	Knier, Benjamin; Hiltensperger, Michael; Sie, Christopher; Aly, Lilian; ... Korn, Thomas
unige:107292	Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping	Di Liberto, Giovanni; Pantelyushin, Stanislav; Kreutzfeldt, Mario; Page, Nicolas; ... Merkler, Doron
unige:115234	Resident-memory T cells in tissue-restricted immune responses: for better or worse?	Steinbach, Karin; Vincenti, Ilena; Merkler, Doron;
unige:109367	The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8+ T cells	Moalli, Federica; Ficht, Xenia; Germann, Philipp; Vladymyrov, Mykhailo; ... Stein, Jens V
unige:109365	The Swiss Multiple Sclerosis Registry (SMSR): study protocol of a participatory, nationwide registry to promote epidemiological and patient-centered MS research	Steinemann, Nina; Kuhle, Jens; Calabrese, Pasquale; Kesselring, Jürg; ... von Wyl, Viktor

Thesis supervisions

unige:113169

Brain-resident memory CD8+ T cells: roles in protection and disease

Vincenti, Ilena;

2017

Scientific Articles

unige:98402	Clival chordoma: a single-centre outcome analysis	Jaegersberg, Max; El Rahal, Amir Mohamed; Dammann, Philipp; Merkler, Doron; ... Schaller, Karl Lothard
unige:98395	Germline PMS2 and somatic POLEexo mutations cause hypermutability of the leading DNA strand in Biallelic Mismatch Repair Deficiency syndrome brain tumors	Andrianova, Maria A; Chetan, Ghati Kasturirangan; Sibin, Madathan Kandi; Mckee, Thomas Alexander; ... Nikolaev, Sergey Igorievich
unige:98396	Increased interleukin-27 cytokine expression in the central nervous system of multiple sclerosis patients	Lalive d'Epinay, Patrice; Kreutzfeldt, Mario; Devergne, Odile; Metz, Imke; ... Pot, Caroline
unige:98394	Interferon-γ-Driven iNOS: A Molecular Pathway to Terminal Shock in Arenavirus Hemorrhagic Fever	Remy, Mélissa; Sahin, Mehmet; Flatz, Lukas Roland; Regen, Tommy; ... Pinschewer, Daniel
unige:98397	Replicating viral vector platform exploits alarmin signals for potent CD8(+) T cell-mediated tumour immunotherapy	Kallert, Sandra M; Darbre, Stéphanie; Bonilla, Weldy V; Kreutzfeldt, Mario; ... Pinschewer, Daniel
unige:100197	STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells	Nunes-Hasler, Paula; Maschalidi, Sophia; Lippens, Carla; Castelbou, Cyril; ... Demaurex, Nicolas
unige:101824	The Immune System Bridges the Gut Microbiota with Systemic Energy Homeostasis: Focus on TLRs, Mucosal Barrier, and SCFAs	Spiljar, Martina; Merkler, Doron; Trajkovski, Mirko;

2016

Scientific Articles

unige:89091	B cell-derived transforming growth factor-β1 expression limits the induction phase of autoimmune neuroinflammation	Bjarnadottir, Kristbjorg; Benkhoucha, Mahdia; Merkler, Doron; Weber, Martin S; ... Lalive d'Epinay, Patrice
unige:86049	Brain-resident memory T cells represent an autonomous cytotoxic barrier to viral infection	Steinbach, Karin; Vincenti, Ilena; Kreutzfeldt, Mario; Page, Nicolas; ... Merkler, Doron
unige:88584	In vivo imaging reveals rapid astrocyte depletion and axon damage in a model of neuromyelitis optica-related pathology	Herwerth, Marina; Kalluri, Sudhakar Reddy; Srivastava, Rajneesh; Kleele, Tatjana; ... Hemmer, Bernhard
unige:94180	Interferon-driven deletion of antiviral B cells at the onset of chronic infection	Fallet, Benedict; Narr, Kerstin; Ertuna, Yusuf I; Remy, Mélissa; ... Pinschewer, Daniel
unige:84462	Macroautophagy Proteins Control MHC Class I Levels on Dendritic Cells and Shape Anti-viral CD8(+) T Cell Responses	Loi, Monica; Müller, Anne; Steinbach, Karin; Niven, Jennifer; ... Gannagé, Monique
unige:96653	Medulloblastoma in children and adults: one distinct disease entity?	Von Bueren, André; Ares Molina, Carmen; Bartoli, Andréa; Fluss, Joel Victor; ... Ansari Djaberi, Marc Georges
unige:94181	Myelinosome formation represents an early stage of oligodendrocyte damage in multiple sclerosis and its animal model	Romanelli, Elisa; Merkler, Doron; Mezydlo, Aleksandra; Weil, Marie-Theres; ... Kerschensteiner, Martin
unige:77875	pDC therapy induces recovery from EAE by recruiting endogenous pDC to sites of CNS inflammation	Duraes, Fernanda V; Lippens, Carla; Steinbach, Karin; Dubrot Armendariz, Juan; ... Hugues, Stéphanie
unige:94182	pMHC affinity controls duration of CD8+ T cell-DC interactions and imprints timing of effector differentiation versus expansion	Ozga, Aleksandra J; Moalli, Federica; Abe, Jun; Swoger, Jim; ... Koritzinsky, Marianne
unige:79115	Reconstruction of single cortical projection neurons reveals primary spine loss in multiple sclerosis	Jürgens, Tanja; Jafari, Mehrnoosh; Kreutzfeldt, Mario; Bahn, Erik; ... Merkler, Doron
unige:88585	TGFβ regulates persistent neuroinflammation by controlling Th1 polarization and ROS production via monocyte-derived dendritic cells	Parsa, Roham; Lund, Harald; Tosevski, Ivana; Zhang, Xing-Mei; ... Harris, Robert A

Thesis supervisions

unige:86373

La nucléoprotéine est nécessaire à l'immunogénicité des vecteurs vaccinaux basés sur les virus de la chorioméningite lymphocytaire recombinants (rLCMV)

Darbre, Stéphanie;

2015

Scientific Articles

unige:77899	IL-27 Induces Th17 Differentiation in the Absence of STAT1 Signaling	Peters, Anneli; Fowler, Kevin D; Chalmin, Fanny; Merkler, Doron; ... Pot, Caroline
unige:45174	Oxysterols regulate encephalitogenic CD4+ T cell trafficking during central nervous system autoimmunity	Chalmin, Fanny; Rochemont, Viviane; Lippens, Carla; Clottu, Aurélie Sarah; ... Pot, Caroline
unige:84085	Recurrent multiple CNS hemangioblastomas with VHL disease treated with pazopanib: a case report and literature review	Migliorini, Denis; Haller, Sven; Merkler, Doron; Pugliesi-Rinaldi, Angela; ... Dietrich, Pierre-Yves