Scapozza, Leonardo

 
 
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2018

Scientific Articles

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Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targetsTrofimov, Valentin; Kicka, Sébastien; Mucaria, Sabrina; Hanna, Nabil; ... Soldati, Thierry
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Autoregulation of Class II Alpha PI3K Activity by Its Lipid-Binding PX-C2 Domain ModuleWang, Haibin; Lo, Wen-Ting; Vujičić Žagar, Andreja; Gulluni, Federico; ... Vadas, Oscar
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Modeling and resistant alleles explain the selectivity of antimalarial compound 49c towards apicomplexan aspartyl proteasesMukherjee, Budhaditya; Tessaro, Francesca; Vahokoski, Juha; Kursula, Inari; ... Soldati-Favre, Dominique
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Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathyGayi, Elinam; Neff, Laurence Anne; Massana Muñoz, Xènia; Ismail, Hesham; ... Scapozza, Leonardo

Preprints

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Identification of novel anti-bacterial compounds from a chemically highly diverse pathways-based library using phenotypic screens in amoebae host modelsKicka, Sébastien; Hanna, Nabil; Chiriano, Gianpaolo; Harrison, Christopher; ... Soldati, Thierry

Thesis supervisions

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Development of new chemical and physical strategies to enhance topical drug deliverySanter, Verena;
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Identification and analysis of the putative AMP-activated protein kinase (AMPK) in blood stream form of Trypanosoma bruceiAmbuehl, Chiara;
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Nanocarrier systems and iontophoresis: complementary approaches for targeted cutaneous delivery of hydrophobic and hydrophilic drugsKandekar, Somnath;

2013

Scientific Articles

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Synthesis and in vitro evaluation of a novel radioligand for αvβ3 integrin receptor imaging: [18F]FPPA-c(RGDfK)Monaco, Alessandra; Zoete, Vincent; Alghisi, Gian Carlo; Rüegg, Curzio; ... Seimbille, Yann

Thesis supervisions

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Cerebrospinal fluid biomarkers for stage determination and treatment outcome evaluation in patients affected by Human African trypanosomiasisTiberti, Natalia;
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From compound to target: chemical proteomics and in silico screening for target identification in Plasmodium falciparumLauciello, Leonardo;
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Genetic and chemical validation of Trypanosoma brucei adenosine kinase, the intracellular target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]-morpholineGraven, Patricia;
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Genomic profiling of Anaplastic Large Cell LymphomaBoi, Michela;
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Intravitreal formulations targeting the retinal vasculature in posterior segment eye diseasesVeurink, Marieke;
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Role of oxidative stress and calcium regulation in Duchenne muscular dystrophy: pharmacological investigationsIsmail, Hesham;
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Synthesis of small molecules via click chemistry for positron emission tomography (PET) imaging of tumor integrin αvβ3 and/or α5β1 expressionMonaco, Alessandra;
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Targeting STAT3 for cancer therapy: definition of mechanisms of action of direct STAT3 inhibitorsBrambilla, Lara;
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Transgenic enrichment strategies for cardiac cells derived from mouse embryonic stem cells using HSV1-TK-ganciclovir and CD-5-fluorouracilHeuking, Pernilla;
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