2020

Scientific Articles

unige:142008	Consensus summary report for CEPI/BC March 12–13, 2020 meeting: Assessment of risk of disease enhancement with COVID-19 vaccines	Lambert, Paul Henri; Ambrosino, Donna M.; Andersen, Svein R.; Baric, Ralph S.; ... Cramer, Jakob P.
unige:149076	Rapid dose-dependent Natural Killer (NK) cell modulation and cytokine responses following human rVSV-ZEBOV Ebolavirus vaccination	Pejoski, David; De Rham, Casimir; Martinez Murillo, Paola Andréa; Santoro, Francesco; ... Siegrist, Claire-Anne

2019

Scientific Articles

unige:143451	Maternal antibodies inhibit neonatal and infant responses to vaccination by shaping the early-life B cell repertoire within germinal centers	Vono, Maria; Eberhardt, Christiane Sigrid; Auderset, Floriane; Mastelic-Gavillet, Beatris; ... Siegrist, Claire-Anne
unige:143450	Neonatal T follicular helper cells are lodged in a pre-T follicular helper stage favoring innate over adaptive germinal center responses	Mastelic-Gavillet, Beatris; Vono, Maria; Gonzalez-Dias, Patrícia; Ferreira, Frederico Moraes; ... Siegrist, Claire-Anne
unige:143480	Reactivating Immunity Primed by Acellular Pertussis Vaccines in the Absence of Circulating Antibodies: Enhanced Bacterial Control by TLR9 Rather Than TLR4 Agonist-Including Formulation	Auderset, Floriane; Ballester, Marie; Mastelic-Gavillet, Beatris; Fontannaz, Paola; ... Siegrist, Claire-Anne
unige:143454	Site-specific DC surface signatures influence CD4+ T cell co-stimulation and lung-homing	Pejoski, David; Ballester, Marie; Auderset, Floriane; Vono, Maria; ... Siegrist, Claire-Anne

2018

Scientific Articles

unige:123150

Overcoming the neonatal limitations of inducing germinal centers through liposome-based adjuvants including c-type lectin agonists trehalose dibehenate or curdlan

Vono, Maria; Eberhardt, Christiane Sigrid; Mohr, Elodie; Auderset, Floriane; ... Siegrist, Claire-Anne

2015

Scientific Articles

unige:80122	Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection	Sommerstein, Rami; Flatz, Lukas Roland; Remy, Mélissa; Malinge, Pauline; ... Pinschewer, Daniel
unige:76370	MF59 Mediates Its B Cell Adjuvanticity by Promoting T Follicular Helper Cells and Thus Germinal Center Responses in Adult and Early Life	Mastelic-Gavillet, Beatris; Eberhardt, Christiane Sigrid; Auderset, Floriane; Castellino, Flora; ... Siegrist, Claire-Anne
unige:76358	Needle-free and adjuvant-free epicutaneous boosting of pertussis immunity: Preclinical proof of concept	Mastelic-Gavillet, Beatris; Mondoulet, Lucie; Dhelft, Véronique; Eberhardt, Christiane Sigrid; ... Siegrist, Claire-Anne
unige:76333	Protective efficacy of individual CD8+ T cell specificities in chronic viral infection	Johnson, Susan; Bergthaler, Andréas; Graw, Frederik; Flatz, Lukas Roland; ... Pinschewer, Daniel

Professional Articles

unige:80105

The Nucleoprotein Is Required for Lymphocytic Choriomeningitis Virus-Based Vaccine Vector Immunogenicity

Darbre, Stéphanie; Johnson, Susan; Kallert, Sandra; Lambert, Paul Henri; ... Pinschewer, Daniel

2013

Scientific Articles

unige:35596

Functional limitations of plasmacytoid dendritic cells limit type I interferon, T cell responses and virus control in early life

Belnoue, Elodie; Fontannaz, Paola; Rochat, Anne-Françoise; Tougne, Chantal; ... Siegrist, Claire-Anne

2012

Scientific Articles

unige:31430	A cationic vaccine adjuvant based on a saturated quaternary ammonium lipid have different in vivo distribution kinetics and display a distinct CD4 T cell-inducing capacity compared to its unsaturated analog	Christensen, Dennis; Henriksen-Lacey, Malou; Kamath, Arun; Lindenstrøm, Thomas; ... Agger, Else Marie
unige:31487	Environmental and T cell-intrinsic factors limit the expansion of neonatal follicular T helper cells but may be circumvented by specific adjuvants	Mastelic-Gavillet, Beatris; Kamath, Arun; Fontannaz, Paola; Tougne, Chantal; ... Siegrist, Claire-Anne
unige:31370	Homing and adhesion patterns determine the cellular composition of the bone marrow plasma cell niche	Belnoue, Elodie; Tougne, Chantal; Rochat, Anne-Françoise; Lambert, Paul Henri; ... Siegrist, Claire-Anne
unige:31724	Synchronization of dendritic cell activation and antigen exposure is required for the induction of Th1/Th17 responses	Kamath, Arun; Mastelic-Gavillet, Beatris; Christensen, Dennis; Rochat, Anne-Françoise; ... Siegrist, Claire-Anne

2010

Scientific Articles

unige:11247	Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity	Flatz, Lukas; Hegazy, A. N.; Bergthaler, Andréas; Verschoor, Admar; ... Pinschewer, Daniel
unige:21227	Frequent failure of adolescent booster responses to tetanus toxoid despite infant immunization: waning of infancy-induced immune memory?	Posfay Barbe, Klara; Kobela, Marie; Sottas, Cédric Ernest; Grillet, Stéphane; ... Siegrist, Claire-Anne
unige:21121	Mode of action of adjuvants: implications for vaccine safety and design	Mastelic-Gavillet, Beatris; Ahmed, Sohail; Egan, William M.; Del Giudice, Giuseppe; ... Lambert, Paul Henri

2009

Scientific Articles

unige:19544	A liposome-based mycobacterial vaccine induces potent adult and neonatal multifunctional T cells through the exquisite targeting of dendritic cells	Kamath, Arun; Rochat, Anne-Françoise; Christensen, Dennis; Agger, Else Marie; ... Siegrist, Claire-Anne
unige:19969	Advocating vaccination of adults aged 60 years and older in Western Europe: statement by the Joint Vaccine Working Group of the European Union Geriatric Medicine Society and the International Association of Gerontology and Geriatrics-European Region	Michel, Jean-Pierre; Chidiac, Christian; Grubeck-Loebenstein, Beatrix; Johnson, Robert W.; ... Werner, Hans-Martin
unige:19564	Coalition of advocates to vaccinate of Western European citizens aged 60 years and older	Michel, Jean-Pierre; Chidiac, Christian; Grubeck-Loebenstein, Beatrix; Johnson, Robert W.; ... Werner, Hans-Martin
unige:5586	Global safety of vaccines: strengthening systems for monitoring, management and the role of GACVS	Autran, Brigitte; Asturias, Edwin J.; Evans, Stephen; Hartigan-Go, Kenneth; ... Wood, David

2008

Scientific Articles

unige:2518	Adult-like anti-mycobacterial T cell and in vivo dendritic cell responses following neonatal immunization with Ag85B-ESAT-6 in the IC31 adjuvant	Kamath, Arun; Rochat, Anne-Françoise; Valenti, Mario Paolo; Agger, Else Marie; ... Siegrist, Claire-Anne
unige:1113	Intradermal vaccine delivery: will new delivery systems transform vaccine administration?	Lambert, Paul Henri; Laurent, Philippe E.;
unige:2517	Protective anti-mycobacterial T cell responses through exquisite in vivo activation of vaccine-targeted dendritic cells	Kamath, Arun; Valenti, Mario Paolo; Rochat, Anne-Françoise; Agger, Else Marie; ... Siegrist, Claire-Anne

2007

Scientific Articles

unige:44927

Protracted course of lymphocytic choriomeningitis virus WE infection in early life: induction but limited expansion of CD8+ effector T cells and absence of memory CD8+ T cells

Belnoue, Elodie; Fontannaz, Paola; Grillet, Stéphane; Lambert, Paul Henri; Siegrist, Claire-Anne

2006

Scientific Articles

unige:72878	Predominant influence of environmental determinants on the persistence and avidity maturation of antibody responses to vaccines in infants	Marchant, Arnaud; Pihlgren Bosch, Maria Astrid Louise; Goetghebuer, Tessa; Weiss, Helen A; ... Siegrist, Claire-Anne
unige:46933	Reduced ability of neonatal and early-life bone marrow stromal cells to support plasmablast survival	Pihlgren Bosch, Maria Astrid Louise; Friedli, Mathieu; Tougne, Chantal; Rochat, Anne-Françoise; ... Siegrist, Claire-Anne

2005

Scientific Articles

unige:46638	Can successful vaccines teach us how to induce efficient protective immune responses?	Lambert, Paul Henri; Liu, Margaret; Siegrist, Claire-Anne;
unige:46641	The immunomodulating properties of human respiratory syncytial virus and immunostimulating complexes containing Quillaja saponin components QH-A, QH-C and ISCOPREP703	Hu, Ke-Fei; Regner, Matthias; Siegrist, Claire-Anne; Lambert, Paul Henri; ... Morein, Bror
unige:46799	Vaccine safety controversies and the future of vaccination programs	François, Guido; Duclos, Philippe; Margolis, Harold; Lavanchy, Daniel; ... Van Damme, Pierre

2004

Scientific Articles

unige:55634	A global perspective on vaccine safety and public health: the Global Advisory Committee on Vaccine Safety	Folb, Peter I; Bernatowska, Ewa; Chen, Robert; Clemens, John; ... Wimalaratne, Omala
unige:55346	Co-administration of CpG oligonucleotides enhances the late affinity maturation process of human anti-hepatitis B vaccine response	Siegrist, Claire-Anne; Pihlgren Bosch, Maria Astrid Louise; Tougne, Chantal; Efler, Sue M; ... Lambert, Paul Henri
unige:55495	Hepatitis B immunisation induces higher antibody and memory Th2 responses in new-borns than in adults	Ota, Martin OC; Vekemans, Johan; Schlegel Heueter, Susanna; Fielding, Katherine; ... Marchant, Arnaud
unige:55491	Influence of complement C3 amount on IgG responses in early life: immunization with C3b-conjugated antigen increases murine neonatal antibody responses	Pihlgren Bosch, Maria Astrid Louise; Fulurija, Alma; Villiers, Marie-Bernadette; Tougne, Chantal; ... Siegrist, Claire-Anne
unige:55486	Partial activation of neonatal CD11c+ dendritic cells and induction of adult-like CD8+ cytotoxic T cell responses by synthetic microspheres	Regner, Matthias; Martinez, Javier; Belnoue, Elodie; Sun, Cheng Min; ... Siegrist, Claire-Anne
unige:55485	Safety and efficacy of immune-stimulating complex-based antigen delivery systems for neonatal immunisation against respiratory syncytial virus infection	Regner, Matthias; Culley, Fiona; Fontannaz, Paola; Hu, Kefei; ... Siegrist, Claire-Anne

2003

Scientific Articles

unige:47578	CD4-independent protective cytotoxic T cells induced in early life by a non-replicative delivery system based on virus-like particles	Martinez, Javier; Regner, Matthias; Kovarik, Jiri; Zarei Haller, Shohreh; ... Siegrist, Claire-Anne
unige:55314	CpG-motifs enhance initial and sustained primary tetanus-specific antibody secreting cell responses in spleen and bone marrow, but are more effective in adult than in neonatal mice	Pihlgren Bosch, Maria Astrid Louise; Tougne, Chantal; Schallert, Nadine; Bozzotti, Paola; ... Siegrist, Claire-Anne
unige:55268	Unresponsiveness to lymphoid-mediated signals at the neonatal follicular dendritic cell precursor level contributes to delayed germinal center induction and limitations of neonatal antibody responses to T-dependent antigens	Pihlgren Bosch, Maria Astrid Louise; Tougne, Chantal; Bozzotti, Paola; Fulurija, Alma; ... Siegrist, Claire-Anne

2002

Scientific Articles

unige:55907	Generation of adult-like antibody avidity profiles after early-life immunization with protein vaccines	Schallert, Nadine; Pihlgren Bosch, Maria Astrid Louise; Kovarik, Jiri; Roduit, Caroline Monique; ... Lambert, Paul Henri
unige:55966	Immunogenicity and protective efficacy of neonatal vaccination against Bordetella pertussis in a murine model: evidence for early control of pertussis	Roduit, Caroline Monique; Bozzotti, Paola; Mielcarek, Nathalie; Lambert, Paul Henri; ... Siegrist, Claire-Anne
unige:55975	Influence of Mycobacterium bovis bacillus Calmette-Guérin on antibody and cytokine responses to human neonatal vaccination	Ota, Martin O C; Vekemans, Johan; Schlegel Heueter, Susanna; Fielding, Katherine; ... Marchant, Arnaud

2001

Scientific Articles

unige:72696	Adjuvant effects of CpG oligodeoxynucleotides on responses against T-independent type 2 antigens	Kovarik, Jiri; Bozzotti, P; Tougne, Chantal; Davis, HL; ... Siegrist, Claire-Anne
unige:72628	Delayed and deficient establishment of the long-term bone marrow plasma cell pool during early life	Pihlgren Bosch, Maria Astrid Louise; Schallert, N; Tougne, Chantal; Bozzotti, P; ... Siegrist, Claire-Anne
unige:72695	Induction of adult-like antibody, Th1, and CTL responses to measles hemagglutinin by early life murine immunization with an attenuated vaccinia-derived NYVAC(K1L) viral vector	Kovarik, Jiri; Gaillard, Muriel; Martinez, Javier; Bozzotti, P; ... Siegrist, Claire-Anne

1999

Scientific Articles

unige:84211	Antigen-Presentation Systems, Immunomodulators, and Immune Responses to Vaccines	Siegrist, Claire-Anne; Lambert, Paul Henri;
unige:74353	Combining DNA and protein vaccines for early life immunization against respiratory syncytial virus in mice	Martinez, Javier; Lin, Xiao; Kovarik, Jiri; Klein, Michael Joséph; ... Siegrist, Claire-Anne